Tyrosinase

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S4921 MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN) <1 mg/mL 39 mg/mL <1 mg/mL
S1652 Monobenzone <1 mg/mL 40 mg/mL 40 mg/mL
S4132 Deoxyarbutin <1 mg/mL 39 mg/mL 39 mg/mL
S4571 Hexylresorcinol <1 mg/mL 38 mg/mL 38 mg/mL
S2375 Aloin 83 mg/mL 83 mg/mL 2 mg/mL
S4997 4-Butylresorcinol -1 mg/mL 34 mg/mL -1 mg/mL
S5174 Kojic acid -1 mg/mL 28 mg/mL -1 mg/mL
S2263 Arbutin 55 mg/mL 55 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S4921

MNS (3,4-Methylenedioxy-β-nitrostyrene, MDBN)

MNS is a tyrosine kinase inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.

S1652

Monobenzone

Monobenzone is a compound used as a topical agent for medical depigmentation. It can specifically block tyrosinase.

S4132

Deoxyarbutin

DeoxyArbutin is a reversible tyrosinase inhibitor, inhibiting tyrosinase activity with IC50 of 50 nM.

S4571

Hexylresorcinol

Hexylresorcinol is an organic compound with local anaesthetic, antiseptic and anthelmintic properties, is a potent inhibitor of mushroom tyrosinase. The IC50 values of hexylresorcinol for monophenolase is 1.24 μM and for diphenolase is 0.85 μM.

S2375

Aloin

Aloin, a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.

S4997New

4-Butylresorcinol

4-Butylresorcinol is a potent inhibitor of tyrosinase and is used in cosmetics as a depigmenting agent.

S9284New

Aloesin

Aloesin is a kind of herbal extraction form the aloe vera. It is a strong inhibitor of tyrosinase activity and up-regulates cyclin E-dependent kinase activity in vitro.

S9089New

Magnoflorine

Magnoflorine, an important compound in Aristolochia, was usually used as an anxiolytic chemical. It shows significant antioxidant activity as a DPPH free radical scavenger and inhibits α-tyrosinase.

S9111New

Isorhamnetin

Isorhamnetin, a natural flavonol aglycon, is a tyrosinase inhibitor and has antioxidant activity.

S5174New

Kojic acid

Kojic acid is a fungal metabolite that inhibits tyrosinase with an IC50 value of 30.6 µM for mushroom tyrosinase. It is a synthetic intermediate used for production of food additives.

S2263

Arbutin

Arbutin is a tyrosinase inhibitor with an IC50 of 1.09 mM.