ALK6 Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S7359 K02288

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

Pan ALK6, IC50: 6.4 nM; ALK6, IC50: 6.4 nM
S7148 ML347

ML347 is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.

Pan ALK6, IC50: 9.83 μM