Retinoid Receptor

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1653 Tretinoin <1 mg/mL 60 mg/mL 6 mg/mL
S2098 Bexarotene <1 mg/mL 8 mg/mL <1 mg/mL
S1276 Adapalene <1 mg/mL 8 mg/mL <1 mg/mL
S1368 Acitretin <1 mg/mL 20 mg/mL <1 mg/mL
S1569 Tazarotene <1 mg/mL 10 mg/mL 10 mg/mL
S4699 Etretinate <1 mg/mL 70 mg/mL 70 mg/mL
S4627 TTNPB (Arotinoid Acid) <1 mg/mL 15 mg/mL <1 mg/mL
S4260 Tamibarotene <1 mg/mL 70 mg/mL 70 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations
S1653

Tretinoin

Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

S2098

Bexarotene

Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.

S1276

Adapalene

Adapalene is a dual RAR and RXR agonist, used in the treatment of acne.

S1368

Acitretin

Acitretin is a second generation retinoid used for psoriasis.

S1569

Tazarotene

Tazarotene is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.

S4699New

Etretinate

Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.

S4627

TTNPB (Arotinoid Acid)

TTNPB (Arotinoid Acid) is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.

S4260

Tamibarotene

Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.

Catalog No. Information Product Use Citations Product Validations
S1653

Tretinoin

Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.

S2098

Bexarotene

Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.

S1276

Adapalene

Adapalene is a dual RAR and RXR agonist, used in the treatment of acne.

S1368

Acitretin

Acitretin is a second generation retinoid used for psoriasis.

S1569

Tazarotene

Tazarotene is a retinoid prodrug of tazarotenic acid, which is a RAR agonist, used to treat psoriasis, acne, and sun damaged skin.

2013, 123(9):3941-51

S4699New

Etretinate

Etretinate is an oral aromatic retinoid acid which is effective in psoriasis and other dermatological syndromes. It activates retinoid receptors, causing an induction of cell differentiation, inhibition of cell proliferation, and inhibition of tissue infiltration by inflammatory cells.

S4627

TTNPB (Arotinoid Acid)

TTNPB (Arotinoid Acid) is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.

S4260

Tamibarotene

Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.