WH-4-023

Catalog No.S7565 Synonyms: KIN001-112, KIN112

WH-4-023 Chemical Structure

Molecular Weight(MW): 568.67

WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.

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Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
Targets
Lck [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
2 nM 6 nM
In vitro

WH-4-023 shows little activity on p38 and KDR. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human EM-2 cell Mny0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4rRTmlvcGmkaYTpc44hd2ZiaIXtZY4hTU1vMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuPVFmNTB6IN88US=> M{j2U3NCVkeHUh?=
human LAMA-84 cell M2PMfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIq0e4lKdmirYnn0bY9vKG:oIHj1cYFvKEyDTVGtPFQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0{Njd6ZT2wOkDPxE1? MWXTRW5ITVJ?
human EoL-1-cell cell NELlcY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1uxXmlvcGmkaYTpc44hd2ZiaIXtZY4hTW:OLUGtZ4VtdCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTlwNUHlMVA3KM7:TR?= M{\uT3NCVkeHUh?=
human MEG-01 cell MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NW\IOnUxUW6qaXLpeIlwdiCxZjDoeY1idiCPRVetNFEh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjZ|ZT2wOUDPxE1? MVPTRW5ITVJ?
human CTV-1 cell M3LXRWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoLkTY5pcWKrdHnvckBw\iCqdX3hckBEXFZvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuNVhmNTB3IN88US=> MWTTRW5ITVJ?
human BL-70 cell NEjZdoxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWLJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTdyIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND63NoUuODVizszN NEHkfG1USU6JRWK=
human K-562 cell NVixZox3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEjs[mtKdmirYnn0bY9vKG:oIHj1cYFvKEtvNU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODBzNkKg{txO M4rxRXNCVkeHUh?=
human BV-173 cell NFfk[XpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3\nfWlvcGmkaYTpc44hd2ZiaIXtZY4hSlZvMUezJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODB3MUSg{txO M{G0OHNCVkeHUh?=
human DOHH-2 cell M2L1d2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUfJcohq[mm2aX;uJI9nKGi3bXHuJGRQUEhvMjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAxPTl5IN88US=> NWK5TGVtW0GQR1XS
human A704 cell MVLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2jmNWlvcGmkaYTpc44hd2ZiaIXtZY4hSTdyNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAyOjdizszN NHry[oRUSU6JRWK=
human NCI-SNU-16 cell M3\3e2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3judWlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLWPOWU0yPiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMEG1O|Ih|ryP MnnKV2FPT0WU
human LC-2-ad cell NULTNFdrT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Ml7ZTY5pcWKrdHnvckBw\iCqdX3hckBNSy1{LXHkJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xOjB|MzFOwG0> NVf5dlZYW0GQR1XS
human LB2518-MEL cell Mme2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3LlTGlvcGmkaYTpc44hd2ZiaIXtZY4hVEJ{NUG4MW1GVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwMES2Olch|ryP NGTEPG1USU6JRWK=
human D-336MG cell M13uPWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUnJcohq[mm2aX;uJI9nKGi3bXHuJGQuOzN4TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA1PjhzIN88US=> NYXqZnVrW0GQR1XS
human LB996-RCC cell NG\tTHlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVjJcohq[mm2aX;uJI9nKGi3bXHuJGxDQTl4LWLDR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODV4Nkig{txO MlvKV2FPT0WU
human Becker cell MXLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVrZVIFUUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB4M{ixJO69VQ>? NEXZNVlUSU6JRWK=
human LB1047-RCC cell M1L3VWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEiydGxKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkC3OVkzKM7:TR?= NUHOcXpqW0GQR1XS
human KS-1 cell NVnsW|I3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWnBZlFmUW6qaXLpeIlwdiCxZjDoeY1idiCNUz2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xPzd3ODFOwG0> Mm\uV2FPT0WU
human MPP-89 cell NF\GPVFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXvJcohq[mm2aX;uJI9nKGi3bXHuJG1RWC16OTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFgzOjlizszN M4XMSXNCVkeHUh?=
human RXF393 cell NILEOpFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUX3WJJkUW6qaXLpeIlwdiCxZjDoeY1idiCUWF[zPVMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjFyNkOzJO69VQ>? NXLld3dmW0GQR1XS
LB831-BLC cell NWHn[4dET3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVjmTY9mUW6qaXLpeIlwdiCxZjDoeY1idiCOQkizNU1DVENiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkGyO|E2KM7:TR?= NF:1d49USU6JRWK=
HUTU-80 cell MkPKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXfJcohq[mm2aX;uJI9nKGi3bXHuJGhWXFVvOECgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlE4PTJ7IN88US=> NY\ifJduW0GQR1XS
A498 cell MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYDJcohq[mm2aX;uJI9nKGi3bXHuJGE1QThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG4PVQ2KM7:TR?= M4L0b3NCVkeHUh?=
MZ1-PC cell MkLpS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYjzNXl3UW6qaXLpeIlwdiCxZjDoeY1idiCPWkGtVGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjJ{N{G2JO69VQ>? M{L2N3NCVkeHUh?=
TE-8 cell NEHYd2pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MoK5TY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yN|kzPCEQvF2= MonrV2FPT0WU
MFH-ino cell  M1XpUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4\HR2lvcGmkaYTpc44hd2ZiaIXtZY4hVU[KLXnuc{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOjN7MkWg{txO M2L2cHNCVkeHUh?=
TE-15 cell NH7vZY1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4rLZ2lvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1Ojd4IN88US=> MnfYV2FPT0WU
NTERA-S-cl-D1 cell NXHRNm9iT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NY\NcopXUW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zQDh3NTFOwG0> NYH5d2R4W0GQR1XS
COLO-829 cell MUnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4jnO2lvcGmkaYTpc44hd2ZiaIXtZY4hS0:OTz24Nlkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjNzMkGyJO69VQ>? NF7kbWxUSU6JRWK=
SW684 cell MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUfReJQ6UW6qaXLpeIlwdiCxZjDoeY1idiCVV{[4OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzJ3OEig{txO NUSx[Gl7W0GQR1XS
OS-RC-2 cell MnzKS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGfVT3pKdmirYnn0bY9vKG:oIHj1cYFvKE:VLWLDMVIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN3MEGxJO69VQ>? Mlf0V2FPT0WU
IST-MES1 cell NITEcGRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2LtdWlvcGmkaYTpc44hd2ZiaIXtZY4hUVOWLV3FV|Eh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjN3N{KzJO69VQ>? NEfwc2JUSU6JRWK=
SNB75 cell NEnERllIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NUPSOppCUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzV5N{Sg{txO MYDTRW5ITVJ?
SW954 cell MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4jp[mlvcGmkaYTpc44hd2ZiaIXtZY4hW1d7NUSgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlM4OTZ|IN88US=> NHHRb4ZUSU6JRWK=
RCC10RGB cell MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2TkV2lvcGmkaYTpc44hd2ZiaIXtZY4hWkOFMUDSS2Ih[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjR{NkOxJO69VQ>? MnzpV2FPT0WU
VA-ES-BJ cell MWjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXzvZVNRUW6qaXLpeIlwdiCxZjDoeY1idiCYQT3FV{1DUiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNE[yOkDPxE1? MWTTRW5ITVJ?
NCI-H1648 cell MV3Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYHRdFVYUW6qaXLpeIlwdiCxZjDoeY1idiCQQ1mtTFE3PDhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkWxOVgzKM7:TR?= NXPvUppNW0GQR1XS
PF-382 cell NHjXeIhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1fHUWlvcGmkaYTpc44hd2ZiaIXtZY4hWEZvM{iyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE44ODd4MzFOwG0> NXPRXWVjW0GQR1XS
human Daudi cell MnjCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIjy[FdKdmirYnn0bY9vKG:oIHj1cYFvKESjdXTpJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE44OTRzMTFOwG0> NXvDZ4ZFW0GQR1XS
SW982 cell M4q4c2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OVgyQSEQvF2= NVXae5M4W0GQR1XS
SW872 cell NUnWeYNkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NULOU2luUW6qaXLpeIlwdiCxZjDoeY1idiCVV{i3NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQDZ2NUig{txO M1L5PXNCVkeHUh?=
TE-12 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYTJcohq[mm2aX;uJI9nKGi3bXHuJHRGNTF{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64PFg{OSEQvF2= M1;PXnNCVkeHUh?=
human HOP-62 cell MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn;FTY5pcWKrdHnvckBw\iCqdX3hckBJV1BvNkKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlkyPTl7IN88US=> M4PFcnNCVkeHUh?=
human NOS-1 cell NEXOVpRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYHBcWlVUW6qaXLpeIlwdiCxZjDoeY1idiCQT2OtNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvQTVyNEWg{txO MoK5V2FPT0WU
human BL-41 cell Mn:xS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2XyXWlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvNEGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlAxODF|IN88US=> Mly2V2FPT0WU
human TGBC24TKB cell NV:1U4RWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXjCPXBnUW6qaXLpeIlwdiCxZjDoeY1idiCWR1LDNlRVU0JiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkCzPFMyKM7:TR?= MlXVV2FPT0WU
human KGN cell MYHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHzs[JdKdmirYnn0bY9vKG:oIHj1cYFvKEuJTjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNFUzOSEQvF2= MYPTRW5ITVJ?
human TK10 cell M1LyNGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHHLV3hKdmirYnn0bY9vKG:oIHj1cYFvKFSNMUCgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlA5PDF6IN88US=> NY\aXpdJW0GQR1XS
human GB-1 cell NGrvdIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYPJcohq[mm2aX;uJI9nKGi3bXHuJGdDNTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkG2NFY1KM7:TR?= MVjTRW5ITVJ?
human GCIY cell MoHsS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWDj[ItEUW6qaXLpeIlwdiCxZjDoeY1idiCJQ1nZJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zOzBzIN88US=> MWHTRW5ITVJ?
human LXF-289 cell NXXqVW5NT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MnrwTY5pcWKrdHnvckBw\iCqdX3hckBNYEZvMki5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4zPzJ3NjFOwG0> M4nBcHNCVkeHUh?=
RL95-2 cell MVnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4nl[GlvcGmkaYTpc44hd2ZiaIXtZY4hWkx7NT2yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU4{OjR|NjFOwG0> MkLTV2FPT0WU
human SW962 cell NX;MdpNqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYTCXGVRUW6qaXLpeIlwdiCxZjDoeY1idiCVV{m2NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOzN5NEKg{txO M{T5OnNCVkeHUh?=
human HT-144 cell NHKzeZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmHoTY5pcWKrdHnvckBw\iCqdX3hckBJXC1zNESgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlQ1PTF5IN8ccS=> NVTs[JlsW0GQR1XS
human IST-SL2 cell M{\jfmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWTVWohpUW6qaXLpeIlwdiCxZjDoeY1idiCLU2StV2wzKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS52N{SyNUDPxE1? M4fV[XNCVkeHUh?=
human NB6 cell M3jhXWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnTJTY5pcWKrdHnvckBw\iCqdX3hckBPSjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLk[5Olk5KM7:TR?= NFWxeXdUSU6JRWK=
human SF126 cell MmnnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkHMTY5pcWKrdHnvckBw\iCqdX3hckBUTjF{NjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuO|MyPzhizszN MYrTRW5ITVJ?
human BOKU cell NYDlSGxoT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXHROI5WUW6qaXLpeIlwdiCxZjDoeY1idiCET1vVJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45ODV{NzFOwG0> NVyxc3o6W0GQR1XS
human BB30-HNC cell NVy2N3FkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Mlf0TY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQDV2N{Kg{txO MoS5V2FPT0WU
human KLE cell M32zUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVLJcohq[mm2aX;uJI9nKGi3bXHuJGtNTSClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwOE[yN|Ih|ryP M4\VeHNCVkeHUh?=
human MLMA cell NWTXRlMzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NEG4c5BKdmirYnn0bY9vKG:oIHj1cYFvKE2OTVGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlkzOzFizszN MkDoV2FPT0WU
human KINGS-1 cell NYTtRolwT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MV\Jcohq[mm2aX;uJI9nKGi3bXHuJGtKVkeVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlk3QDl5IN88US=> NIL3W4VUSU6JRWK=
human ES6 cell MonYS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4Dl[mlvcGmkaYTpc44hd2ZiaIXtZY4hTVN4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6wOVQxOSEQvF2= NF\aRYtUSU6JRWK=
human SH-4 cell MYfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkHuTY5pcWKrdHnvckBw\iCqdX3hckBUUC12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6xNlA2PSEQvF2= M1vLZ3NCVkeHUh?=
human D-263MG cell NVHT[mF{T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MU\Jcohq[mm2aX;uJI9nKGi3bXHuJGQuOjZ|TVegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlI5QDV|IN88US=> Ml;rV2FPT0WU
human SF268 cell M{jtdGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlfiTY5pcWKrdHnvckBw\iCqdX3hckBUTjJ4ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOFg3QDJizszN NYf5VHk{W0GQR1XS
human NB17 cell NEHtU3pIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUDJcohq[mm2aX;uJI9nKGi3bXHuJG5DOTdiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1{Lk[yPFc2KM7:TR?= MXjTRW5ITVJ?
human DMS-114 cell M3PYTWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGfJ[YJKdmirYnn0bY9vKG:oIHj1cYFvKESPUz2xNVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjd7MEKyJO69VQ>? NH3ocJNUSU6JRWK=
MC116 cell M4m3dWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M{LNRWlvcGmkaYTpc44hd2ZiaIXtZY4hVUNzMU[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlg2PzB2IN88US=> MXvTRW5ITVJ?
human NCI-H747 cell M1nZPGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFvIVphKdmirYnn0bY9vKG:oIHj1cYFvKE6FST3IO|Q4KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS55NEG1PUDPxE1? MlfZV2FPT0WU
human A388 cell M4jGSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M36xd2lvcGmkaYTpc44hd2ZiaIXtZY4hSTN6ODDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUG0MlY4PThizszN NHj5V5FUSU6JRWK=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 12 mg/mL warmed (21.1 mM)
Ethanol 6 mg/mL warmed (10.55 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 568.67
Formula

C32H36N6O4

CAS No. 837422-57-8
Storage powder
Synonyms KIN001-112, KIN112

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Related Antibodies

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID