WH-4-023

Catalog No.S7565 Synonyms: KIN001-112, KIN112

WH-4-023 Chemical Structure

Molecular Weight(MW): 568.67

WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.

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Purity & Quality Control

Choose Selective Src Inhibitors

Biological Activity

Description WH-4-023 is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
Targets
Lck [1]
(Cell-free assay)
Src [1]
(Cell-free assay)
2 nM 6 nM
In vitro

WH-4-023 shows little activity on p38 and KDR. [1]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human EM-2 cell M13lbWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Ml\RTY5pcWKrdHnvckBw\iCqdX3hckBGVS1{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz65NYUuODhizszN MY\TRW5ITVJ?
human LAMA-84 cell NGDMTJVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXr2boFbUW6qaXLpeIlwdiCxZjDoeY1idiCOQV3BMVg1KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:Oy55OHWtNFYh|ryP NVrGWGdYW0GQR1XS
human EoL-1-cell cell NX3L[npsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3PPW2lvcGmkaYTpc44hd2ZiaIXtZY4hTW:OLUGtZ4VtdCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTlwNUHlMVA3KM7:TR?= M3KyWHNCVkeHUh?=
human MEG-01 cell MmSzS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MX\Jcohq[mm2aX;uJI9nKGi3bXHuJG1GTy1yMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuOlNmNTB3IN88US=> MVvTRW5ITVJ?
human CTV-1 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mnr3TY5pcWKrdHnvckBw\iCqdX3hckBEXFZvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuNVhmNTB3IN88US=> NXvGWHA5W0GQR1XS
human BL-70 cell NGLX[49Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2ewXmlvcGmkaYTpc44hd2ZiaIXtZY4hSkxvN{CgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME20Mlcz\S1yNTFOwG0> Mm\OV2FPT0WU
human K-562 cell NIq0cXZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHLGd41KdmirYnn0bY9vKG:oIHj1cYFvKEtvNU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xODBzNkKg{txO NUPPOHZ[W0GQR1XS
human BV-173 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHTYeIxKdmirYnn0bY9vKG:oIHj1cYFvKEKYLUG3N{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODByNUG0JO69VQ>? NWPRS3lIW0GQR1XS
human DOHH-2 cell MmK1S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFnido9KdmirYnn0bY9vKG:oIHj1cYFvKESRSFitNkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODByNUm3JO69VQ>? M4jlbHNCVkeHUh?=
human A704 cell Mn;DS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4nlXWlvcGmkaYTpc44hd2ZiaIXtZY4hSTdyNDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuNFAyOjdizszN M4jpb3NCVkeHUh?=
human NCI-SNU-16 cell Mki3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MULJcohq[mm2aX;uJI9nKGi3bXHuJG5EUS2VTmWtNVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjBzNUeyJO69VQ>? M1PWTHNCVkeHUh?=
human LC-2-ad cell NV7pcVlPT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3nyVGlvcGmkaYTpc44hd2ZiaIXtZY4hVENvMj3h[EBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvODJyM{Og{txO MUXTRW5ITVJ?
human LB2518-MEL cell NIDaXG5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MmS0TY5pcWKrdHnvckBw\iCqdX3hckBNSjJ3MUitUWVNKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5yNE[2O{DPxE1? MmD0V2FPT0WU
human D-336MG cell NYTL[phtT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MojFTY5pcWKrdHnvckBw\iCqdX3hckBFNTN|Nl3HJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4xPDZ6MTFOwG0> NFzx[25USU6JRWK=
human LB996-RCC cell NWTYXpRLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MmTlTY5pcWKrdHnvckBw\iCqdX3hckBNSjl7Nj3SR2Mh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB3Nk[4JO69VQ>? NYG1PXFZW0GQR1XS
human Becker cell MWTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NWm0NXZCUW6qaXLpeIlwdiCxZjDoeY1idiCEZXPr[ZIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB4M{ixJO69VQ>? NWT2VnVXW0GQR1XS
human LB1047-RCC cell M3Tifmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NEDFU4hKdmirYnn0bY9vKG:oIHj1cYFvKEyEMUC0O{1TS0NiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkC3OVkzKM7:TR?= Mn3PV2FPT0WU
human KS-1 cell MmLQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEOzVHpKdmirYnn0bY9vKG:oIHj1cYFvKEuVLUGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlA4PzV6IN88US=> M1rtfnNCVkeHUh?=
human MPP-89 cell NYXYW|lbT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NW\idJppUW6qaXLpeIlwdiCxZjDoeY1idiCPUGCtPFkh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjB6MkK5JO69VQ>? NWn3bJBpW0GQR1XS
human RXF393 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2XCdmlvcGmkaYTpc44hd2ZiaIXtZY4hWliIM{mzJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4yODZ|MzFOwG0> NVLPbHc6W0GQR1XS
LB831-BLC cell M2ewSGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mmr4TY5pcWKrdHnvckBw\iCqdX3hckBNSjh|MT3CUGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjF{N{G1JO69VQ>? Mmr0V2FPT0WU
HUTU-80 cell M4rrRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUPneodwUW6qaXLpeIlwdiCxZjDoeY1idiCKVWTVMVgxKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5zN{WyPUDPxE1? M{i3WXNCVkeHUh?=
A498 cell MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXjJcohq[mm2aX;uJI9nKGi3bXHuJGE1QThiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1yLkG4PVQ2KM7:TR?= MXXTRW5ITVJ?
MZ1-PC cell NU\3RZBXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX\BdG1LUW6qaXLpeIlwdiCxZjDoeY1idiCPWkGtVGMh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjJ{N{G2JO69VQ>? NHPNfGpUSU6JRWK=
TE-8 cell M{[zUmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn;STY5pcWKrdHnvckBw\iCqdX3hckBVTS16IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD6yN|kzPCEQvF2= NUPVcYtoW0GQR1XS
MFH-ino cell  NEH2V3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlHKTY5pcWKrdHnvckBw\iCqdX3hckBOTkhvaX7vJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zOzl{NTFOwG0> NEXOdYFUSU6JRWK=
TE-15 cell MofIS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1XJZ2lvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUWgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlI1Ojd4IN88US=> MmruV2FPT0WU
NTERA-S-cl-D1 cell MkjoS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NX34SWJ4UW6qaXLpeIlwdiCxZjDoeY1idiCQVFXSRU1UNWOuLVSxJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4zQDh3NTFOwG0> M3zqSnNCVkeHUh?=
COLO-829 cell M1nIRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVzJcohq[mm2aX;uJI9nKGi3bXHuJGNQVE9vOEK5JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE4{OTJzMjFOwG0> MVjTRW5ITVJ?
SW684 cell NUjGOGdOT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkHTTY5pcWKrdHnvckBw\iCqdX3hckBUXzZ6NDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuN|I2QDhizszN NVPkbYlIW0GQR1XS
OS-RC-2 cell NI\URYxIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWfXe|RYUW6qaXLpeIlwdiCxZjDoeY1idiCRUz3SR{0zKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC5|NUCxNUDPxE1? NWnwT5FQW0GQR1XS
IST-MES1 cell NXG2XGZkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MknqTY5pcWKrdHnvckBw\iCqdX3hckBKW1RvTVXTNUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzV5MkOg{txO MWLTRW5ITVJ?
SNB75 cell MonWS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWP0bJRVUW6qaXLpeIlwdiCxZjDoeY1idiCVTlK3OUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzV5N{Sg{txO MlnvV2FPT0WU
SW954 cell M3zVZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUW5[YR4UW6qaXLpeIlwdiCxZjDoeY1idiCVV{m1OEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvOzdzNkOg{txO NVfqXVFTW0GQR1XS
RCC10RGB cell NVi0OJFiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NUXlNVVGUW6qaXLpeIlwdiCxZjDoeY1idiCUQ1OxNHJISiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTBwNEK2N|Eh|ryP MkmzV2FPT0WU
VA-ES-BJ cell NEjT[XpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MW\Jcohq[mm2aX;uJI9nKGi3bXHuJHZCNUWVLVLKJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE41PjJ4IN88US=> NXfpT5NsW0GQR1XS
NCI-H1648 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{\I[GlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLVixOlQ5KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OC53MUW4NkDPxE1? NYrvWFI6W0GQR1XS
PF-382 cell M3yzZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NH;CRmhKdmirYnn0bY9vKG:oIHj1cYFvKFCILUO4NkBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVAvPzB5NkOg{txO MWHTRW5ITVJ?
human Daudi cell MmDHS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MnjSTY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuO|E1OTFizszN M3OwSnNCVkeHUh?=
SW982 cell NG\5cI1Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWrJcohq[mm2aX;uJI9nKGi3bXHuJHNYQTh{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MD64OVgyQSEQvF2= NYe2T5ZwW0GQR1XS
SW872 cell NYjqOIdYT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NF7IV3VKdmirYnn0bY9vKG:oIHj1cYFvKFOZOEeyJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE45PjR3ODFOwG0> MkeyV2FPT0WU
TE-12 cell NHT0WWZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4SwSmlvcGmkaYTpc44hd2ZiaIXtZY4hXEVvMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2wMlg5QDNzIN88US=> NXG4RoxzW0GQR1XS
human HOP-62 cell NULv[XNmT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4XHbmlvcGmkaYTpc44hd2ZiaIXtZY4hUE:SLU[yJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NE46OTV7OTFOwG0> NE\HSY9USU6JRWK=
human NOS-1 cell MnG3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Ml;hTY5pcWKrdHnvckBw\iCqdX3hckBPV1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUCuPVUxPDVizszN NH3KfZZUSU6JRWK=
human BL-41 cell M3PSOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MXrJcohq[mm2aX;uJI9nKGi3bXHuJGJNNTRzIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT6wNFAyOyEQvF2= MmLPV2FPT0WU
human TGBC24TKB cell MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2i5NWlvcGmkaYTpc44hd2ZiaIXtZY4hXEeEQ{K0WGtDKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5yM{izNUDPxE1? NHjrNXVUSU6JRWK=
human KGN cell NYrHWVJxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVK3RmN7UW6qaXLpeIlwdiCxZjDoeY1idiCNR16gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlA2OjFizszN MmTlV2FPT0WU
human TK10 cell MnflS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV;Jcohq[mm2aX;uJI9nKGi3bXHuJHRMOTBiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkC4OFE5KM7:TR?= M2\xZ3NCVkeHUh?=
human GB-1 cell NWL2SoxST3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2S0UWlvcGmkaYTpc44hd2ZiaIXtZY4hT0JvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuNVYxPjRizszN Mn64V2FPT0WU
human GCIY cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXvJcohq[mm2aX;uJI9nKGi3bXHuJGdEUVliY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zLkKzNFEh|ryP NX7Cb2FEW0GQR1XS
human LXF-289 cell MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NVHHTWE4UW6qaXLpeIlwdiCxZjDoeY1idiCOWF[tNlg6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS5{N{K1OkDPxE1? Mn\ZV2FPT0WU
RL95-2 cell MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoXRTY5pcWKrdHnvckBw\iCqdX3hckBTVDl3LUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlMzPDN4IN88US=> NGXxcmZUSU6JRWK=
human SW962 cell MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlvRTY5pcWKrdHnvckBw\iCqdX3hckBUXzl4MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuN|M4PDJizszN M3fncHNCVkeHUh?=
human HT-144 cell MmO0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3yzdmlvcGmkaYTpc44hd2ZiaIXtZY4hUFRvMUS0JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU41PDVzNzFOoI0> MXTTRW5ITVJ?
human IST-SL2 cell M2PXSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NFS1[XRKdmirYnn0bY9vKG:oIHj1cYFvKEmVVD3TUFIh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yNjR5NEKxJO69VQ>? M1LRc3NCVkeHUh?=
human NB6 cell NE\m[VJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXzYTWhsUW6qaXLpeIlwdiCxZjDoeY1idiCQQk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlY6Pjl6IN88US=> NGDuN2VUSU6JRWK=
human SF126 cell NWrwTnBlT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWXJcohq[mm2aX;uJI9nKGi3bXHuJHNHOTJ4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MT63N|E4QCEQvF2= MWLTRW5ITVJ?
human BOKU cell NITBSYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWe2fGY6UW6qaXLpeIlwdiCxZjDoeY1idiCET1vVJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NU45ODV{NzFOwG0> M{\QUXNCVkeHUh?=
human BB30-HNC cell M2XB[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmflTY5pcWKrdHnvckBw\iCqdX3hckBDSjNyLVjOR{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvQDV2N{Kg{txO MWXTRW5ITVJ?
human KLE cell MXHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEjRfVNKdmirYnn0bY9vKG:oIHj1cYFvKEuORTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUGuPFYzOzJizszN NXLyRmxtW0GQR1XS
human MLMA cell Mo[5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NIrqNGVKdmirYnn0bY9vKG:oIHj1cYFvKE2OTVGgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xMlkzOzFizszN NEXaSpZUSU6JRWK=
human KINGS-1 cell MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYPh[nhxUW6qaXLpeIlwdiCxZjDoeY1idiCNSV7HV{0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OS57Nki5O{DPxE1? M4fyTnNCVkeHUh?=
human ES6 cell NWXjelh4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1OyRmlvcGmkaYTpc44hd2ZiaIXtZY4hTVN4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6wOVQxOSEQvF2= Mk\yV2FPT0WU
human SH-4 cell MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmiwTY5pcWKrdHnvckBw\iCqdX3hckBUUC12IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mj6xNlA2PSEQvF2= NVX4NoN{W0GQR1XS
human D-263MG cell MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFy1XoJKdmirYnn0bY9vKG:oIHj1cYFvKERvMk[zUWch[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjJ6OEWzJO69VQ>? MoTCV2FPT0WU
human SF268 cell M{fPZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NX[wUllmUW6qaXLpeIlwdiCxZjDoeY1idiCVRkK2PEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVIvPDh4OEKg{txO M{TzTHNCVkeHUh?=
human NB17 cell NVnzR2w2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M134Z2lvcGmkaYTpc44hd2ZiaIXtZY4hVkJzNzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuOlI5PzVizszN M3LkR3NCVkeHUh?=
human DMS-114 cell NVjaOpV6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NFnldZpKdmirYnn0bY9vKG:oIHj1cYFvKESPUz2xNVQh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjd7MEKyJO69VQ>? M2Ptb3NCVkeHUh?=
MC116 cell NEXHOFVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mnr1TY5pcWKrdHnvckBw\iCqdX3hckBOSzFzNjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuPFU4ODRizszN NFTKfpRUSU6JRWK=
human NCI-H747 cell NXS2NolJT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlHnTY5pcWKrdHnvckBw\iCqdX3hckBPS0lvSEe0O{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPzRzNUmg{txO NFXyV4tUSU6JRWK=
human A388 cell NX:wR3g6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVXJcohq[mm2aX;uJI9nKGi3bXHuJGE{QDhiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1zND62O|U5KM7:TR?= MVnTRW5ITVJ?

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Protocol

Solubility (25°C)

In vitro DMSO 12 mg/mL warmed (21.1 mM)
Ethanol 6 mg/mL warmed (10.55 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 568.67
Formula

C32H36N6O4

CAS No. 837422-57-8
Storage powder
in solvent
Synonyms KIN001-112, KIN112

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Src Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID