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Tanshinone IIA
Synonyms: Tanshinone B
Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.
Tanshinone IIA Chemical Structure
CAS: 568-72-9
Selleck's Tanshinone IIA has been cited by 17 Publications
2 Customer Reviews
Purity & Quality Control
Batch:
Purity:
99.85%
99.85
Tanshinone IIA Related Products
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Biological Activity
| Description | Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor. | |
|---|---|---|
| Targets |
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| In vitro | ||||
| In vitro | Tanshinone IIA (Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases. Tanshinone IIA protects cardiac myocytes against oxidative stress-induced apoptosis. The in vivo protection is mediated by increased scavenging of oxygen free radicals, prevention of lipid peroxidation and upregulation of the Bcl-2/Bax ratio. [1] Recently, tanshinone IIA was demonstrated to induce cell death and apoptosis in a variety of tumors. [2] | |||
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| In Vivo | ||
| In vivo | LD50: Rats 25g/kg (i.g.) [3] | |
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Chemical Information & Solubility
| Molecular Weight | 294.34 | Formula | C19H18O3 |
| CAS No. | 568-72-9 | SDF | Download Tanshinone IIA SDF |
| Smiles | CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C | ||
| Storage (From the date of receipt) | |||
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In vitro |
DMSO : 1 mg/mL ( (3.39 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.) Water : Insoluble Ethanol : Insoluble |
Molecular Weight Calculator |
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In vivo Add solvents to the product individually and in order. |
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