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Moxifloxacin HCl

Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent.

Catalog No.S1465

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50mg

USD 97

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Moxifloxacin HCl Chemical Structure
Molecular Weight: 437.89

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Quality Control & MSDS

Related Compound Libraries

Moxifloxacin HCl is available in the following compound libraries:

FDA Approved Drug Library (96-well) Chemical Library (96-well)

Product Information

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Research Area
Research Area
Dr. Antonino Maria Sparta demonstrates a breakthrough in leukemia research by utilizing two inhibitors produced by Selleck Chemicals.

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S1465	Moxifloxacin HCl	<1 mg/mL	88 mg/mL	<1 mg/mL
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Product Description

Biological Activity Chemical Information Tech Support & FAQs

Biological Activity

Moxifloxacin(Avelox, Avalox) is a fourth generation synthetic fluoroquinolone antibacterial agent. Moxifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase and topoisomerase IV, which is an enzyme necessary to separate bacterial DNA, thereby inhibiting cell replication. ^[1]

Chemical Information

Download Moxifloxacin HCl SDF

Molecular Weight (MW)	437.89
Formula	C₂₁H₂₄FN₃O₄.HCl
CAS No.	186826-86-8
Synonyms	Avelox, Avalox

Solubility (25°C) DMSO 88 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Storage	2 years -20°CPowder
	2 weeks4°Cin DMSO
	6 months-80°Cin DMSO

Chemical Name	1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

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Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Related Topoisomerase Inhibitors

Camptothecin
Camptothecin (Camptohecine, 20-(S)-Camptothecin, CPT, NSC100880) is a specific inhibitor of DNA topoisomerase I (Topo I) with IC50 of 0.68 μM.
Amonafide
Amonafide (NSC-308847) is a selective topoisomerase II inhibitor.
SN-38
SN-38 is an active metabolite of CPT-11 that inhibits DNA topoisomerase I.
ABT-888 (Veliparib)

ABT-888 (Veliparib, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with K_i of 5.2 nM and 2.9 nM, respectively.
Olaparib (AZD2281)

Olaparib (AZD2281, KU0059436) is a selective inhibitor of PARP1 and PARP2 with IC50 of 5 nM and 1 nM, respectively.
Iniparib (BSI-201)

BSI-201 (Iniparib, SAR240550) is a PARP1 inhibitor.
KU-55933

KU-55933 is a potent and specific ATM inhibitor with IC50 and K_i of 13 nM and 2.2 nM, respectively.
Rucaparib (AG-014699 , PF-01367338)

Rucaparib (AG-014699, PF-01367338) is an inhibitor of PARP with K_i of 1.4 nM.
INO-1001
INO-1001 is a potent inhibitor of PARP with IC50 of 50 nM and a mediator of oxidant-induced myocyte dysfunction during reperfusion.
BIBR 1532
BIBR 1532 is a potent and selective telomerase inhibitor with IC50 of 100 nM.

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