| S2457 |
Clindamycin HCl
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Clindamycin HCl inhibits protein synthesis by acting on the 50S ribosomal, used for the treatment of bacterial infections.
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Proc Natl Acad Sci U S A, 2016, 113(50):14408-14413
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| S7894 |
Tunicamycin
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Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.
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Proc Natl Acad Sci U S A, 2025, 122(22):e2505975122
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Cell Rep, 2025, 44(5):115686
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Eur Endod J, 2024, 9(4):335-343
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| S5159 |
Doxycycline
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Doxycycline (Vibramycin, Doxytetracycline, Doxiciclina, Doxycyclinum) is an antibiotic that is used in the treatment of a number of types of infections caused by bacteria and protozoa. Doxycycline is also a nonspecific matrix metalloproteinase (MMP) inhibitor.
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Nature, 2025, 10.1038/s41586-025-09222-5
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Cell Stem Cell, 2025, S1934-5909(25)00181-X
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Nat Commun, 2025, 16(1):7898
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| S9046 |
Berberine
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Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.
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J Inflamm Res, 2025, 18:10919-10937
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BMC Biol, 2024, 22(1):280
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Chin Med, 2024, 19(1):128.
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| S1097 |
BTZ043 Racemate
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BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
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Drug Deliv Transl Res, 2021, 11(4):1766-1778
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J Med Chem, 2020, 28;63(10):5367-5386
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Blood Adv, 2019, 3(5):797-812
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| S1399 |
Teicoplanin
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Teicoplanin (Teichomycin,Targocid,MDL-507) is a glycopeptide antibiotic, used to treat serious infections caused by Gram-positive bacteria.
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Front Microbiol, 2022, 13:884034
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ACS Omega, 2022, 7(48):43657-43664
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Bioeng Transl Med, 2021, 6(1):e10196
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| S3015 |
Amoxicillin
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Amoxicillin (Amoxycillin) is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms.
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Ther Drug Monit, 2023, 10.1097/FTD.0000000000001100
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J Pharm Biomed Anal, 2022, 219:114904
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ChemMedChem, 2022, e202200043
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| S5535 |
Moxifloxacin
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Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.
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Microorganisms, 2022, 10(7)1421
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Transl Vis Sci Technol, 2018, 7(2):11
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J Pharmacol Toxicol Methods, 2017, 90:39-47
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| S5492 |
Econazole
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Econazole is a broad spectrum antimycotic with some action against Gram positive bacteria.
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Glia, 2025, 73(11):2289-2304
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Toxicol Appl Pharmacol, 2023, 475:116638
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Acta Pharm Sin B, 2022, 12(7):3085-3102
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| S1839 |
Chloroxine
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Chloroxine is a synthetic antibacterial compound that is effective in the treatment of dandruff and seborrheic dermatitis when incorporated in a shampoo.
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Biosensors (Basel), 2023, 13(6)571
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ACS Synth Biol, 2022, 11(8):2820-2828
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Front Microbiol, 2020, 10:2936
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