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Calcitriol (Rocaltrol)

Catalog No.S1466
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Calcitriol (Rocaltrol) Chemical Structure

  • [Ala92]-p16 (84-103)

    [Ala92]-p16 (84-103) is a CDK inhibitor with IC50 of 1.5μM for cyclin-dependent kinase-4 (cdk4)/cyclin D1

  • Bax inhibitor peptide,negative control

    Bax inhibitor peptide,negative control is a negative control peptide for the Bax inhibitor peptides V5 and P5.

  • JIP-1(153-163)

    JNK and p38 MAPK inhibitor

  • STF-62247

    Targeting VHL-deficient RCC cells, in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 μM).

  • BTZ043 racemate

    BTZ043 racemate is a decaprenylphosphoryl-b-D-ribose 2’-epimerase inhibitor with MIC of 2.3 and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.

  • GSK690693

    GSK690693 is a pan-Akt kinase inhibitor,IC50 of Akt 1, 2, and 3 at 2, 13, and 9 nM respectively.

  • Odanacatib (MK 0822)

    cathepsin K inhibitor with an IC50 of 0.2nM.

  • Malotilate

    Malotilate is a liver protein metabolism improved compound.

  • PA-824

    PA-824 is an experimental anti-tuberculosis drug with MIC of less than 1 μg/mL for tuberculosis.

Biological Activity

Calcitriol, also called 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3, is the hormonally active form of vitamin D with three hydroxyl groups (abbreviated 1,25-(OH)2D3 or simply 1,25(OH)2D). It increases the level of calcium (Ca2+) in the blood by increasing the uptake of calcium from the gut into the blood, decreasing the transfer of calcium from blood to the urine by the kidney, and increasing the release of calcium into the blood from bone. [1]

Molecular Weight (WM): 416.64
Formula:

C27H44O3

CAS No.: 32222-06-3
Synonyms:
Calcijex, Silkis, Rocaltrol, Topitriol, Cholecalciferol
Dissolve in (25°C): DMSO ≥83mg/mL 
Water <1mg/mL 
Ethanol ≥83mg/mL 
Storage: 2 years-20°CPowder
1 week-4°Cin DMSO
1 month-80°in DMSO

Quality Control & MSDS

View current batch:
COA H-NMR

Research Area

Related Inhibitors

Recommended Screening Libraries

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