P-gp Inhibitors & Chemicals

Cat.No.	Product Name	Information	Product Citations
S1481	LY335979 (Zosuquidar 3HCl)	LY335979 (Zosuquidar) is a potent modulator of P-glycoprotein-mediated multidrug resistance with K_i of 60 nM.	Pharmacol Res, 2013, 67(1):79-83
S8028	Tariquidar	Tariquidar (XR9576) is a potent and selective noncompetitive inhibitor of P-glycoprotein with K_d of 5.1 nM.
S1082	Vismodegib (GDC-0449)	GDC-0449 (Vismodegib, HhAntag691) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM.	Gastroenterology, 2012, 143(5):1319-29.e1-11 Hepatology, 2011, 54(5):1580-90 Gut, 2012, 61(9):1323-9

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