Insulin-like growth factor 1 receptor

Cat.No. Product Name Feedback Added

S1012

BMS-536924

Feb 2010
BMS-536924 is a small molecule ATP-competitive IGF-IR kinase inhibitor with an IC50 of 80 nM.
S1086

BMS-554417

Jul 2009
Inhibitor of IGF-IR/ IR (insulin receptor),IC50 at 67.9 and 50.6 nmol/L respectively.
S1124

BMS-754807

Nov 2009
IGF-1R inhibitor with an IC50 of 13nM.
S2703

GSK1838705A 

Oct 2011
GSK1838705A is a potent small-molecule IGF-IR, the insulin receptor and anaplastic lymphoma kinase (ALK) inhibitor with IC50 of 2.0, 1.6 and 0.5 nM, respectively.
S1093

GSK1904529A

Jul 2009
GSK1904529A, is a inhibitor of IGF-IR (IC50= 27 nM) and IR (IC50= 25 nM).
S1088

NVP-ADW742

Jul 2009
NVP-ADW742 is an IGF-1R inhibitor with an IC50 of 0.1 to 0.2 μM.
S1034

NVP-AEW541

Apr 2009
NVP-AEW541 is an IGF-IR inhibitor with an IC50 of median 3.6 μM.
S1091

OSI-906

Jul 2009
IGF-1R inhibitor (EC50 < 400 nM).
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Dongfeng Chen, The Rausing Lab
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"I am very satisfied with your product and costumer service. Bortezomib works very well in our assay, it is comparably cheaper than other inhibitors that we tested is more reliable for our assays. We see a great effect by using 10nM concentration."

R.B. Cambridge
"I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more."

Zhenghe John Wang Assistant Professor, Case Western Reserve University
"We have purchased LBH-589, Saha and MS-275 from you and they all worked well."

Jenny Sun
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Yu Wang, Harvard University
"The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research."

Philip Seeman, Toronto University
"Your LY404039 compound was well synthesized, its complicated stereochemical structure confirmed by NMR spectroscopy, and was biologically excellent in acting on brain dopamine receptors."

Dung-Fang Lee
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