Integrin

Sigaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S7077 Cilengitide trifluoroacetate 8 mg/mL 100 mg/mL <1 mg/mL
S8008 RGD (Arg-Gly-Asp) Peptides 12 mg/mL <1 mg/mL <1 mg/mL
S2885 A-205804 <1 mg/mL 60 mg/mL <1 mg/mL
S3085 Tirofiban <1 mg/mL 0.005 mg/mL <1 mg/mL
S7540 SB273005 <1 mg/mL 90 mg/mL 16 mg/mL
S8594 Tirofiban Hydrochloride 95 mg/mL 95 mg/mL 95 mg/mL
S8306 Leukadherin-1 <1 mg/mL 15 mg/mL <1 mg/mL
S7834 Cyclo (-RGDfK) 84 mg/mL 100 mg/mL <1 mg/mL
S7844 Cyclo(RGDyK) 100 mg/mL 100 mg/mL 20 mg/mL
Catalog No. Information Product Use Citations Product Validations
S7077

Cilengitide trifluoroacetate

Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

S8008

RGD (Arg-Gly-Asp) Peptides

RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.

S2885

A-205804

A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.

S3085

Tirofiban

Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.

S7540

SB273005

SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.

S7834

Cyclo (-RGDfK)

Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.

S7844

Cyclo(RGDyK)

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

S8306New

Leukadherin-1

Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)).

S8594New

Tirofiban Hydrochloride

Tirofiban Hydrochloride is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation.

Catalog No. Information Product Use Citations Product Validations
S7077

Cilengitide trifluoroacetate

Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

S8008

RGD (Arg-Gly-Asp) Peptides

RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.

S2885

A-205804

A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively.

S3085

Tirofiban

Tirofiban (MK-383) is a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.

S7540

SB273005

SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.

S7834

Cyclo (-RGDfK)

Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor.

S7844

Cyclo(RGDyK)

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Catalog No. Information Product Use Citations Product Validations
S8594New

Tirofiban Hydrochloride

Tirofiban Hydrochloride is the hydrochloride salt form of tirofiban, a selective platelet GPIIb/IIIa antagonist which inhibits platelet aggregation.

Catalog No. Information Product Use Citations Product Validations
S8306New

Leukadherin-1

Leukadherin-1 (LA1) is a small molecule agonist that enhances CD11b/CD18-dependent cell adhesion to its ligand ICAM-1(an agonist for the complement receptor 3 (CD11b/CD18)).