Serine/threonin kinase

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S8388 ML-7 HCl <1 mg/mL 90 mg/mL <1 mg/mL
S8465 GSK'872 (GSK2399872A) <1 mg/mL 76 mg/mL 40 mg/mL
S8366 CRT0066101 82 mg/mL 25 mg/mL 2 mg/mL
S8215 BAY 1217389 <1 mg/mL 100 mg/mL 3 mg/mL
S7188 CID755673 <1 mg/mL 43 mg/mL <1 mg/mL
Catalog No. Information Product Use Citations Product Validations
S8388

ML-7 HCl

ML-7 is an inhibitor of smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+-calmodulin-dependent and -independent smooth muscle MLCKs.

S8465New

GSK'872 (GSK2399872A)

GSK'872 (GSK2399872A) is a potent and selective RIP3 kinase inhibitor which binds RIP3 kinase domain with high affinity (IC50=1.8 nM) and inhibits kinase activity with IC50 of 1.3 nM. It has minimal cross-reactivity.

S8366New

CRT0066101

CRT0066101 is a small molecule PKD family specific inhibitor which specifically blocks PKD1/2 activity and does not suppress PKCα/PKCβ/PKCε activity in multiple.

S8215New

BAY 1217389

BAY 1217389 is an orally bioavailable, selective inhibitor of the serine/threonine kinase monopolar spindle 1 (Mps1) with IC50 values below 10 nmol/L while showing an excellent selectivity profile.

S7188

CID755673

CID755673 is a cell-active pan-PKD1/2/3 inhibitor with IC50 of 180 nM, 280nM, and 227 nM, respectively, about 200-fold selectivity over other CAMKs.

Catalog No. Information Product Use Citations Product Validations
A5116New

Daxx Rabbit Recombinant mAb

WBELISA

A5134New

CDC5 Rabbit Recombinant mAb

WBELISA

A5149New

ULK1 Rabbit Recombinant mAb

A5157New

PKN2 Rabbit Recombinant mAb

WBELISA

A5166New

RIP Rabbit Recombinant mAb

Tags: STK activation | STK kinase family | STK family kinases | STK activity | STK cancer | Serine/threonine kinase | STK phosphorylation | STK inhibition | STK inhibitors cancer | STK inhibitor review