Factor Xa

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Factor Xa Inhibitors (3)


Cat.No. Product Name Information Product Use Citation Customer Product Validation
S3002 Rivaroxaban Rivaroxaban is a direct inhibitor of Factor Xa with Ki and IC50 of 0.4 nM and 0.7 nM in cell-free assays, respectively.
S1593 Apixaban Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.
  • J Thromb Haemost, 2014, 12(2):147-58
  • PLoS Comput Biol, 2015, 11(2):e1004118
  • Thrombo Res, 2015, 10.1016/j.thromres.2015.04.030
S7280 Edoxaban Edoxaban is a selective factor Xa inhibitor with Ki of 0.561 nM, >10 000-fold selectivity over thrombin and FIXa, and is also an orally bioavailable anticoagulant drug.

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Cat.No. Product Name Solubility (25°C)
Water DMSO Ethanol
S3002 Rivaroxaban <1 mg/mL 87 mg/mL <1 mg/mL
S1593 Apixaban <1 mg/mL 18 mg/mL <1 mg/mL
S7280 Edoxaban <1 mg/mL 100 mg/mL <1 mg/mL
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