CYP2 Selective Inhibitors

Catalog No. Product Name Information Selective / Pan IC50 / Ki
S4221 Benzbromarone

Benzbromarone is a CYP2C9 inhibitor, it binds to CYP2C9 with Ki value of 19.3 nM.

Selective CYP2C9, Ki: 19.3 nM
S2262 Apigenin

Apigenin is a potent P450 inhibitor for CYP2C9 with Ki of 2 μM.

Selective CYP2C9, Ki: 2 μM
S2268 Baicalein

Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor.

Selective
S2046 Pioglitazone HCl

Pioglitazone HCl is a hydrochloride salt form of pioglitazone which is a cytochrome P450 (CYP)2C8 and CYP3A4 enzymes inhibitor for CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively.

Pan CYP2C9, Ki: 32.1 μM; CYP2C8, Ki: 1.7 μM
S2187 Avasimibe

Avasimibe inhibits ACAT with IC50 of 3.3 μM, also inhibits human P450 isoenzymes CYP2C9, CYP1A2 and CYP2C19 with IC50 of 2.9 μM, 13.9 μM and 26.5 μM, respectively.

Pan CYP2C19, IC50: 26.5 μM; CYP2C9, IC50: 2.9 μM