VU-29

Catalog No.S1970

For research use only.

VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor, with EC50 of 9 nM and Ki=244 nM for rat mGluR5, which is selective for mGluR5 relative to other mGluR subtypes.

VU-29 Chemical Structure

CAS No. 890764-36-0

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Biological Activity

Description VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor, with EC50 of 9 nM and Ki=244 nM for rat mGluR5, which is selective for mGluR5 relative to other mGluR subtypes.
Targets
rat mGluR5 [1] rat mGluR5 [1]
9 nM(EC50) 244 nM(Ki)

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 384.39
Formula

C22H16N4O3

CAS No. 890764-36-0
Storage 3 years -20°C powder
2 years -80°C in solvent

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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