Vindesine sulfate

Synonyms: Desacetyl Vinblastine amide, DAVA, DVA, VDS

Vindesine sulfate, a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities. Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.

Vindesine sulfate Chemical Structure

Vindesine sulfate Chemical Structure

CAS: 59917-39-4

Selleck's Vindesine sulfate has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 98.60%
98.60

Vindesine sulfate Related Products

Choose Selective Microtubule Associated Inhibitors

Biological Activity

Description Vindesine sulfate, a vinca alkaloid derived from Catharanthus roseus, is a potent inhibitor of mitosis with antineoplastic activities. Vindesine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death.
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Chemical Information & Solubility

Molecular Weight 852 Formula

C43H57N5O11S

CAS No. 59917-39-4 SDF --
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (117.37 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : Insoluble


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In vivo
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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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