Sapropterin Dihydrochloride

Catalog No.S9568 Synonyms: Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride

Sapropterin Dihydrochloride Chemical Structure

Molecular Weight(MW): 314.17

Sapropterin Dihydrochloride, a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator.

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Biological Activity

Description Sapropterin Dihydrochloride, a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4), is a phenylalanine hydroxylase activator.

Protocol

References

Solubility (25°C)

In vitro DMSO 63 mg/mL (200.52 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 314.17
Formula

C9H17Cl2N5O3

CAS No. 69056-38-8
Storage powder
in solvent
Synonyms Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03493412 Not yet recruiting Peripheral Artery Disease|Peripheral Arterial Disease University of Nebraska Omaha August 2018 Phase 4
NCT03493412 Not yet recruiting Peripheral Artery Disease|Peripheral Arterial Disease University of Nebraska Omaha August 2018 Phase 4
NCT01412437 Withdrawn PKU Children''s Research Institute|Georgetown University April 2011 Not Applicable
NCT01412437 Withdrawn PKU Children''s Research Institute|Georgetown University April 2011 Not Applicable
NCT01274026 Completed Phenylketonuria|Behavior and Behavior Mechanisms|PAH Gene Expression Tulane University School of Medicine|BioMarin Pharmaceutical|Tulane University January 2011 --
NCT01274026 Completed Phenylketonuria|Behavior and Behavior Mechanisms|PAH Gene Expression Tulane University School of Medicine|BioMarin Pharmaceutical|Tulane University January 2011 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Hydroxylase Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID