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Ranitidine

Name: Ranitidine
Brand: Selleck Chemicals
SKU: S5662
Rating: 5 (3 reviews)

Synonyms: AH-19065

Catalog No.S5662 Purity: 98%

Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.

Ranitidine Chemical Structure

CAS: 66357-35-5

Selleck's Ranitidine has been cited by 3 publications

Purity & Quality Control

Batch: S566201 DMSO] 63 mg/mL] false] ] ] false] ] ] false Purity: 98%

Ranitidine Related Products

Related Targets	H1 receptor H2 receptor H3 receptor H4 receptor	Click to Expand
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Signaling Pathway

Histamine Receptor Signaling Pathway

Choose Selective Histamine Receptor Inhibitors

Biological Activity

Description	Ranitidine(AH-19065) is an H2 histamine receptor antagonist that works by blocking histamine and thus decreasing the amount of acid released by cells of the stomach.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05399927	Completed	Music Therapy\|Cardiovascular Diseases\|Critical Care\|Emergencies	Universidad Miguel Hernandez de Elche	July 2015	Not Applicable
NCT01539655	Completed	Medullary Thyroid Cancer	Sanofi	February 2012	Phase 1
NCT01017198	Completed	Advanced Solid Tumors	Biogen	November 2009	Phase 1

Chemical Information & Solubility

Molecular Weight	314.40	Formula	C₁₃H₂₂N₄O₃S
CAS No.	66357-35-5	SDF	--
Smiles	CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 63 mg/mL ( (200.38 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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