Mizolastine

Synonyms: SL 850324

Mizolastine (SL 850324) is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.

Mizolastine  Chemical Structure

Mizolastine Chemical Structure

CAS: 108612-45-9

Purity & Quality Control

Batch: S210701 0.5MNAOH] 6 mg/mL] false] DMSO] Insoluble] false] Water] Insoluble] false Purity: 99.95%
99.95

Mizolastine Related Products

Choose Selective Histamine Receptor Inhibitors

Biological Activity

Description Mizolastine (SL 850324) is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic reactions.
Targets
Histamine H1 receptor [1]
47 nM

Chemical Information & Solubility

Molecular Weight 432.49 Formula

C24H25FN6O

CAS No. 108612-45-9 SDF --
Smiles CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5
Storage (From the date of receipt)

In vitro
Batch:

0.5MNAOH : 6 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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