Phosphonoacetic acid

Catalog No.S3356 Synonyms: PAA

For research use only.

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

Phosphonoacetic acid Chemical Structure

CAS No. 4408-78-0

Purity & Quality Control

Choose Selective Antiviral Inhibitors

Biological Activity

Description

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 140.03
Formula

C2H5O5P

CAS No. 4408-78-0
Storage 3 years -20°C powder
2 years -80°C in solvent

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05478135 Active not recruiting Device: NAVIFY Oncology Hub Oncology Prova Health Limited|Hoffmann-La Roche May 15 2022 Not Applicable
NCT04466488 Active not recruiting Behavioral: Choice Architecture HIV/AIDS|Tuberculosis Johns Hopkins University|University of Witwatersrand South Africa|National Institute of Allergy and Infectious Diseases (NIAID) September 15 2021 Not Applicable
NCT04817761 Recruiting Drug: Calaspargase pegol (S95015) Acute Lymphoblastic Leukemia Institut de Recherches Internationales Servier|ADIR a Servier Group company|Servier July 7 2021 Phase 2|Phase 3
NCT04540458 Completed Other: 3D printed model|Other: Placebo Maternal-Fetal Relations|Paternal Behavior|Maternal Behavior Creighton University February 4 2020 Not Applicable
NCT03335488 Recruiting Drug: RAVICTI|Drug: NaPBA Urea Cycle Disorder Horizon Therapeutics LLC|Horizon Pharma Ireland Ltd. Dublin Ireland February 20 2018 Phase 4

(data from https://clinicaltrials.gov, updated on 2022-08-01)

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