Phosphonoacetic acid

For research use only.

Catalog No.S3356 Synonyms: PAA

Phosphonoacetic acid Chemical Structure

CAS No. 4408-78-0

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

Purity & Quality Control

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Biological Activity

Description

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. Phosphonoacetic acid exhibits anti-viral activities.

Protocol

Solubility (25°C)

In vitro DMSO 28 mg/mL (199.95 mM)
Water 28 mg/mL (199.95 mM)
Ethanol '''28 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 140.03
Formula

C2H5O5P

CAS No. 4408-78-0
Storage powder
in solvent
Synonyms PAA

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

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Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04466488 Not yet recruiting Behavioral: Choice Architecture HIV/AIDS|Tuberculosis Johns Hopkins University|University of Witwatersrand South Africa|National Institute of Allergy and Infectious Diseases (NIAID) September 1 2021 Not Applicable
NCT04817761 Not yet recruiting Drug: Calaspargase pegol (S95015) Acute Lymphoblastic Leukemia Institut de Recherches Internationales Servier|ADIR a Servier Group company|Servier June 2021 Phase 2|Phase 3
NCT04540458 Recruiting Other: 3D printed model|Other: Placebo Maternal-Fetal Relations|Paternal Behavior|Maternal Behavior Creighton University February 4 2020 Not Applicable
NCT03335488 Recruiting Drug: RAVICTI|Drug: NaPBA Urea Cycle Disorder Horizon Therapeutics LLC|Horizon Pharma Ireland Ltd. Dublin Ireland February 20 2018 Phase 4
NCT03385824 Completed Behavioral: Self-Advocacy for Independent Life (SAIL) TBI (Traumatic Brain Injury) Craig Hospital February 1 2018 Not Applicable

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID