Home DNA Damage/DNA Repair Antiviral inhibitor Phosphonoacetic acid

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Phosphonoacetic acid Antiviral inhibitor

Cat.No.S3356

Phosphonoacetic acid (PAA) is an active endogenous metabolite that possesses a restricted potential to block DNA biosynthesis. This compound exhibits anti-viral activities.

Phosphonoacetic acid Antiviral inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 140.03

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Quality Control

Batch: S335601 DMSO]28 mg/mL]false]Water]28 mg/mL]false]Ethanol]28 mg/mL]false Purity: 98.91%
98.91

Solubility

In vitro
Batch:

DMSO : 28 mg/mL (199.95 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 28 mg/mL

Ethanol : 28 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%
% Tween 80
% ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 140.03 Formula

C2H5O5P

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 4408-78-0 -- Storage of Stock Solutions

Synonyms PAA Smiles OC(=O)C[P](O)(O)=O

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06168656 Not yet recruiting
Mobile Application|Expectant Fathers|Antenatal Education
Pamukkale University
 December 31 2023 Not Applicable
NCT05718180 Not yet recruiting
Labor Obstetric
University of Padova|Azienda Ospedaliera di Padova
 June 1 2023 Not Applicable
NCT05776264 Completed
Chronic Lung Disease|Cardiopulmonary Disease
Columbia University
 March 29 2023 Not Applicable
NCT05895175 Recruiting
Perinatal Disorder
Fundación IVI
 July 1 2022 --

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