Pentosan Polysulfate Sodium
For research use only.
Catalog No.S3500 Synonyms: PPS, Elmiron
CAS No. 140207-93-8, 37319-17-8
Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.
Purity & Quality Control
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|Description||Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.|
|In vitro||Water||100 mg/mL|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|CAS No.||140207-93-8, 37319-17-8|
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation ()|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take μL DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT04869904||Not yet recruiting||Procedure: dental and plaque sampling||Periodontitis|Alzheimer Disease||Centre Hospitalier Universitaire de Nice||June 1 2021||--|
|NCT04685343||Recruiting||Behavioral: Quantitative Sensory Testing|Other: fMRI||Primary Dysmenorrhea||Mclean Hospital|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)||December 14 2020||Not Applicable|
|NCT04910009||Completed||Other: Four sessions of practical privacy education||Education||Gazi University||November 13 2020||Not Applicable|
|NCT04595032||Recruiting||Device: 3DCRT IMRT VMAT SBRT||Metastatic Disease||National Cancer Institute Naples||September 11 2020||--|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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