Pentosan Polysulfate Sodium

For research use only.

Catalog No.S3500 Synonyms: PPS, Elmiron

Pentosan Polysulfate Sodium Chemical Structure

CAS No. 140207-93-8, 37319-17-8

Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.

Purity & Quality Control

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Biological Activity

Description Pentosan Polysulfate Sodium (PPS, Elmiron) is an orally bioavailable, semi-synthetic medication with anti-inflammatory and pro-chondrogenic properties. Pentosan Polysulfate Sodium also exhibits anti-HIV-1 activity.
Targets
HIV-1 [1]
()

Protocol

Solubility (25°C)

In vitro Water 100 mg/mL
DMSO Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight
Formula

(C5H6Na2O10S2)n

CAS No. 140207-93-8, 37319-17-8
Storage powder
in solvent
Synonyms PPS, Elmiron

In vivo Formulation Calculator (Clear solution)

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04869904 Not yet recruiting Procedure: dental and plaque sampling Periodontitis|Alzheimer Disease Centre Hospitalier Universitaire de Nice June 1 2021 --
NCT04685343 Recruiting Behavioral: Quantitative Sensory Testing|Other: fMRI Primary Dysmenorrhea Mclean Hospital|Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) December 14 2020 Not Applicable
NCT04910009 Completed Other: Four sessions of practical privacy education Education Gazi University November 13 2020 Not Applicable
NCT04595032 Recruiting Device: 3DCRT IMRT VMAT SBRT Metastatic Disease National Cancer Institute Naples September 11 2020 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID