Home Immunology & Inflammation ROS chemical Norgestrel For research use only.

Norgestrel

Synonyms: WY-3707, SH-70850, SH-850, FH 122-A

Norgestrel (WY-3707, SH-70850, SH-850, FH 122-A) is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.

Norgestrel Chemical Structure

Norgestrel Chemical Structure

CAS: 6533-00-2

Purity & Quality Control

Batch: S570901 DMSO] 62 mg/mL] false] Ethanol] 21 mg/mL] false] Water] Insoluble] false Purity: 99.91%
99.91

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Biological Activity

Description Norgestrel (WY-3707, SH-70850, SH-850, FH 122-A) is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05896384 Recruiting
Healthy
Boehringer Ingelheim
 December 7 2023 Phase 1
NCT06048536 Recruiting
Contraception
Viatris Inc.
 March 7 2023 Phase 2
NCT04131517 Terminated
Healthy Female Participants
UCB Biopharma SRL|UCB Pharma
 October 23 2019 Phase 1
NCT03745144 Completed
Relapsing Multiple Sclerosis (RMS)
Merck KGaA Darmstadt Germany
 January 17 2019 Phase 1

Chemical Information & Solubility

Molecular Weight 312.45 Formula

C21H28O2
CAS No. 6533-00-2 SDF --
Smiles CCC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 62 mg/mL ( (198.43 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 21 mg/mL

Water : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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