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Nerol ROS chemical

Cat.No.S4970

Nerol (Cis-Geraniol, Neryl alcohol) is a monoterpene found in many essential oils such as lemongrass and hops. This compound has antifungal activity, and it can trigger mitochondrial dysfunction and disruption via elevation of Ca2+ and ROS leading to apoptosis.
Nerol ROS chemical Chemical Structure

Chemical Structure

Molecular Weight: 154.25

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Chemical Information, Storage & Stability

Molecular Weight 154.25 Formula

C10H18O

 Storage (From the date of receipt) 2 years  -20°C  liquid
CAS No. 106-25-2 -- Storage of Stock Solutions

Synonyms Cis-Geraniol, Neryl alcohol Smiles CC(=CCCC(=CCO)C)C

Solubility

In vitro
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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Mechanism of Action

In vivo
Nerol possesses a possible anxiolytic effect in mice. In the open field test, groups treated with this compound show a significant decrease in motor activity (number of crossings, rearings and groomings) when compared with vehicle group. In the elevated plus-maze test, these groups significantly increase the number of entries and time of permanence in the open arms. In the light-dark test, they show a significant increase the time of permanence in the room clear when compared with vehicle group. In the rota rod test, the groups treated with this chemical do not show modification in time spent and number of falls in the revolving bar when compared with vehicle group[1].
References

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