Midostaurin

Synonyms: PKC412, CGP 41251

Midostaurin is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.

Midostaurin Chemical Structure

Midostaurin Chemical Structure

CAS No. 120685-11-2

Purity & Quality Control

Midostaurin Related Products

Signaling Pathway

Cell Data

Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
EOL-1 Cytotoxicity assay 72 hrs Cytotoxicity against human EOL-1 cells after 72 hrs by MTS assay, IC50 = 0.0038 μM. 29350920
MOLM13 Cytotoxicity assay 72 hrs Cytotoxicity against human MOLM13 cells after 72 hrs by MTS assay, IC50 = 0.0047 μM. 29350920
MV4-11 Cytotoxicity assay 72 hrs Cytotoxicity against human MV4-11 cells after 72 hrs by cell titer-blue assay, IC50 = 0.012 μM. 19654408
RS4-11 Function assay 2 hrs Inhibition of FLT3 ITD mutant autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assay, IC50 = 0.013 μM. 19654408
RS4-11 Function assay 2 hrs Inhibition of FLT3 autophosphorylation in human RS4-11 cells after 2 hrs by electrochemiluminescence assay, IC50 = 0.015 μM. 19654408
Sf9 Function assay 4 hrs Inhibition of wild type GST-tagged FLT3 kinase domain (Y567 to S993) (unknown origin) expressed in baculovirus infected insect Sf9 cells using Her2 peptide as substrate after 4 hrs by Kinase-Glo assay, IC50 = 0.037 μM. 26081023
MV4-11 Function assay 72 hrs Inhibition of FLT3 ITD homozygous mutant in human MV4-11 cells assessed as cell growth inhibition after 72 hrs by MTS assay, GI50 = 0.038 μM. 26081023
MOLM-13 Function assay 72 hrs Inhibition of FLT3 ITD heterozygous mutant in human MOLM-13 cells assessed as cell growth inhibition after 72 hrs by MTS assay, GI50 = 0.055 μM. 26081023
Sf9 Function assay 90 mins Inhibition of recombinant GST-tagged Aurora-A kinase domain (S123 to S401) (unknown origin) expressed in insect Sf9 cells using tetra(LRRASLG) peptide as substrate after 90 mins by Kinase-Glo assay, IC50 = 0.08 μM. 26081023
FDC-P1 Function assay 48 hrs Inhibition of human FMS expressed in growth factor dependent mouse FDC-P1 cells assessed as inhibition of FMS-mediated cell proliferation in presence human CSF1 after 48 hrs by resazurin dye reduction assay, IC50 = 0.142 μM. 20156689
A375 Toxicity assay 72 hrs Toxicity against human A375 cells after 72 hrs by cell titer-blue assay, IC50 = 0.18 μM. 19654408
FDC-P1 Function assay 48 hrs Inhibition of mouse GM-CSF-stimulated cell proliferation of growth factor dependent mouse FDC-P1 cells expressing human FMS after 48 hrs by resazurin dye reduction assay, IC50 = 0.2 μM. 20156689
BAF3 Antiproliferative assay Antiproliferative activity against mouse BAF3 cells transformed with ZNF198-FGFR1 construct, IC50 = 0.2 μM. 21936542
Sf9 Function assay 120 mins Inhibition of recombinant GST-tagged VEGFR2 kinase domain (V789 to V1356) (unknown origin) expressed in insect Sf9 cells using polyGlu4:Tyr peptide as substrate after 120 mins by Kinase-Glo assay, IC50 = 0.25 μM. 26081023
RS4:11 Function assay 72 hrs Inhibition of wild type homozygous FLT3 in human RS4:11 cells assessed as cell growth inhibition after 72 hrs by MTS assay, GI50 = 0.4 μM. 26081023
U937 Cytotoxicity assay 72 hrs Cytotoxicity against FLT3-deficient human U937 cells assessed as cell growth inhibition after 72 hrs by MTS assay, GI50 = 1.4 μM. 26081023
SJ-GBM2 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SJ-GBM2 cells 29435139
A673 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for A673 cells 29435139
SK-N-MC qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-MC cells 29435139
U-2 OS qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for U-2 OS cells 29435139
Saos-2 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Saos-2 cells 29435139
SK-N-SH qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for SK-N-SH cells 29435139
LAN-5 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for LAN-5 cells 29435139
Rh18 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for Rh18 cells 29435139
OHS-50 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for OHS-50 cells 29435139
MG 63 (6-TG R) qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Primary screen for MG 63 (6-TG R) cells 29435139
NB1643 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for NB1643 cells 29435139
Rh18 qHTS assay qHTS of pediatric cancer cell lines to identify multiple opportunities for drug repurposing: Confirmatory screen for Rh18 cells 29435139
MOLM13 Apoptosis assay 10 nM 72 hrs Induction of apoptosis in human MOLM13 cells assessed as caspase-3 activation at 10 nM after 72 hrs by immunoblotting analysis 29350920
EOL-1 Apoptosis assay 10 nM 72 hrs Induction of apoptosis in human EOL-1 cells assessed as caspase-3 activation at 10 nM after 72 hrs by immunoblotting analysis 29350920
SN12C Function assay Identifying Small Molecule Inhibitors of Pancreatic Cancer Stem Cells (SN12C, Adherent), Potency = 1.6626 μM. ChEMBL
MV-4-11 Growth Inhibition Assay Inhibition of human MV-4-11 cell growth in a cell viability assay, IC50 = 0.01983 μM. SANGER
NKM-1 Growth Inhibition Assay Inhibition of human NKM-1 cell growth in a cell viability assay, IC50 = 0.03942 μM. SANGER
CGTH-W-1 Growth Inhibition Assay Inhibition of human CGTH-W-1 cell growth in a cell viability assay, IC50 = 0.04265 μM. SANGER
SW982 Growth Inhibition Assay Inhibition of human SW982 cell growth in a cell viability assay, IC50 = 0.04558 μM. SANGER
EoL-1-cell Growth Inhibition Assay Inhibition of human EoL-1-cell cell growth in a cell viability assay, IC50 = 0.05208 μM. SANGER
KASUMI-1 Growth Inhibition Assay Inhibition of human KASUMI-1 cell growth in a cell viability assay, IC50 = 0.06016 μM. SANGER
NCI-H1755 Growth Inhibition Assay Inhibition of human NCI-H1755 cell growth in a cell viability assay, IC50 = 0.06273 μM. SANGER
MES-SA Growth Inhibition Assay Inhibition of human MES-SA cell growth in a cell viability assay, IC50 = 0.07544 μM. SANGER
HCC1395 Growth Inhibition Assay Inhibition of human HCC1395 cell growth in a cell viability assay, IC50 = 0.08428 μM. SANGER
D-336MG Growth Inhibition Assay Inhibition of human D-336MG cell growth in a cell viability assay, IC50 = 0.08754 μM. SANGER
CHP-212 Growth Inhibition Assay Inhibition of human CHP-212 cell growth in a cell viability assay, IC50 = 0.08773 μM. SANGER
KM12 Growth Inhibition Assay Inhibition of human KM12 cell growth in a cell viability assay, IC50 = 0.09275 μM. SANGER
A204 Growth Inhibition Assay Inhibition of human A204 cell growth in a cell viability assay, IC50 = 0.10052 μM. SANGER
CAL-51 Growth Inhibition Assay Inhibition of human CAL-51 cell growth in a cell viability assay, IC50 = 0.10709 μM. SANGER
NALM-6 Growth Inhibition Assay Inhibition of human NALM-6 cell growth in a cell viability assay, IC50 = 0.10803 μM. SANGER
NCI-H2342 Growth Inhibition Assay Inhibition of human NCI-H2342 cell growth in a cell viability assay, IC50 = 0.10881 μM. SANGER
MONO-MAC-6 Growth Inhibition Assay Inhibition of human MONO-MAC-6 cell growth in a cell viability assay, IC50 = 0.11136 μM. SANGER
A431 Growth Inhibition Assay Inhibition of human A431 cell growth in a cell viability assay, IC50 = 0.11216 μM. SANGER
LC-2-ad Growth Inhibition Assay Inhibition of human LC-2-ad cell growth in a cell viability assay, IC50 = 0.11345 μM. SANGER
NCI-H650 Growth Inhibition Assay Inhibition of human NCI-H650 cell growth in a cell viability assay, IC50 = 0.11708 μM. SANGER
KGN Growth Inhibition Assay Inhibition of human KGN cell growth in a cell viability assay, IC50 = 0.11741 μM. SANGER
A427 Growth Inhibition Assay Inhibition of human A427 cell growth in a cell viability assay, IC50 = 0.11918 μM. SANGER
769-P Growth Inhibition Assay Inhibition of human 769-P cell growth in a cell viability assay, IC50 = 0.12082 μM. SANGER
EFO-21 Growth Inhibition Assay Inhibition of human EFO-21 cell growth in a cell viability assay, IC50 = 0.12972 μM. SANGER
KS-1 Growth Inhibition Assay Inhibition of human KS-1 cell growth in a cell viability assay, IC50 = 0.13006 μM. SANGER
SNU-449 Growth Inhibition Assay Inhibition of human SNU-449 cell growth in a cell viability assay, IC50 = 0.1317 μM. SANGER
SW1710 Growth Inhibition Assay Inhibition of human SW1710 cell growth in a cell viability assay, IC50 = 0.13316 μM. SANGER
ABC-1 Growth Inhibition Assay Inhibition of human ABC-1 cell growth in a cell viability assay, IC50 = 0.13415 μM. SANGER
NY Growth Inhibition Assay Inhibition of human NY cell growth in a cell viability assay, IC50 = 0.13748 μM. SANGER
SNU-387 Growth Inhibition Assay Inhibition of human SNU-387 cell growth in a cell viability assay, IC50 = 0.13872 μM. SANGER
H4 Growth Inhibition Assay Inhibition of human H4 cell growth in a cell viability assay, IC50 = 0.13963 μM. SANGER
ALL-PO Growth Inhibition Assay Inhibition of human ALL-PO cell growth in a cell viability assay, IC50 = 0.14546 μM. SANGER
HuO-3N1 Growth Inhibition Assay Inhibition of human HuO-3N1 cell growth in a cell viability assay, IC50 = 0.15463 μM. SANGER
LB1047-RCC Growth Inhibition Assay Inhibition of human LB1047-RCC cell growth in a cell viability assay, IC50 = 0.15487 μM. SANGER
HT-1080 Growth Inhibition Assay Inhibition of human HT-1080 cell growth in a cell viability assay, IC50 = 0.15982 μM. SANGER
PANC-03-27 Growth Inhibition Assay Inhibition of human PANC-03-27 cell growth in a cell viability assay, IC50 = 0.1602 μM. SANGER
MG-63 Growth Inhibition Assay Inhibition of human MG-63 cell growth in a cell viability assay, IC50 = 0.16437 μM. SANGER
TCCSUP Growth Inhibition Assay Inhibition of human TCCSUP cell growth in a cell viability assay, IC50 = 0.16469 μM. SANGER
KYSE-270 Growth Inhibition Assay Inhibition of human KYSE-270 cell growth in a cell viability assay, IC50 = 0.16778 μM. SANGER
GDM-1 Growth Inhibition Assay Inhibition of human GDM-1 cell growth in a cell viability assay, IC50 = 0.17262 μM. SANGER
HUTU-80 Growth Inhibition Assay Inhibition of human HUTU-80 cell growth in a cell viability assay, IC50 = 0.17279 μM. SANGER
AGS Growth Inhibition Assay Inhibition of human AGS cell growth in a cell viability assay, IC50 = 0.17352 μM. SANGER
MFH-ino Growth Inhibition Assay Inhibition of human MFH-ino cell growth in a cell viability assay, IC50 = 0.17455 μM. SANGER
HuCCT1 Growth Inhibition Assay Inhibition of human HuCCT1 cell growth in a cell viability assay, IC50 = 0.17856 μM. SANGER
HOP-62 Growth Inhibition Assay Inhibition of human HOP-62 cell growth in a cell viability assay, IC50 = 0.18073 μM. SANGER
CAS-1 Growth Inhibition Assay Inhibition of human CAS-1 cell growth in a cell viability assay, IC50 = 0.18165 μM. SANGER
PA-1 Growth Inhibition Assay Inhibition of human PA-1 cell growth in a cell viability assay, IC50 = 0.18499 μM. SANGER
T98G Growth Inhibition Assay Inhibition of human T98G cell growth in a cell viability assay, IC50 = 0.18995 μM. SANGER
GI-ME-N Growth Inhibition Assay Inhibition of human GI-ME-N cell growth in a cell viability assay, IC50 = 0.19475 μM. SANGER
YKG-1 Growth Inhibition Assay Inhibition of human YKG-1 cell growth in a cell viability assay, IC50 = 0.19568 μM. SANGER
U031 Growth Inhibition Assay Inhibition of human U031 cell growth in a cell viability assay, IC50 = 0.19698 μM. SANGER
8-MG-BA Growth Inhibition Assay Inhibition of human 8-MG-BA cell growth in a cell viability assay, IC50 = 0.1981 μM. SANGER
G-402 Growth Inhibition Assay Inhibition of human G-402 cell growth in a cell viability assay, IC50 = 0.20253 μM. SANGER
G-361 Growth Inhibition Assay Inhibition of human G-361 cell growth in a cell viability assay, IC50 = 0.20853 μM. SANGER
CAL-54 Growth Inhibition Assay Inhibition of human CAL-54 cell growth in a cell viability assay, IC50 = 0.20859 μM. SANGER
NTERA-S-cl-D1 Growth Inhibition Assay Inhibition of human NTERA-S-cl-D1 cell growth in a cell viability assay, IC50 = 0.20895 μM. SANGER
NCI-H810 Growth Inhibition Assay Inhibition of human NCI-H810 cell growth in a cell viability assay, IC50 = 0.21027 μM. SANGER
CAL-120 Growth Inhibition Assay Inhibition of human CAL-120 cell growth in a cell viability assay, IC50 = 0.21061 μM. SANGER
EFM-19 Growth Inhibition Assay Inhibition of human EFM-19 cell growth in a cell viability assay, IC50 = 0.21213 μM. SANGER
LCLC-103H Growth Inhibition Assay Inhibition of human LCLC-103H cell growth in a cell viability assay, IC50 = 0.21496 μM. SANGER
CAKI-1 Growth Inhibition Assay Inhibition of human CAKI-1 cell growth in a cell viability assay, IC50 = 0.21505 μM. SANGER
G-401 Growth Inhibition Assay Inhibition of human G-401 cell growth in a cell viability assay, IC50 = 0.22339 μM. SANGER
NMC-G1 Growth Inhibition Assay Inhibition of human NMC-G1 cell growth in a cell viability assay, IC50 = 0.22359 μM. SANGER
NCI-H2030 Growth Inhibition Assay Inhibition of human NCI-H2030 cell growth in a cell viability assay, IC50 = 0.23006 μM. SANGER
HCT-116 Growth Inhibition Assay Inhibition of human HCT-116 cell growth in a cell viability assay, IC50 = 0.23568 μM. SANGER
SNU-423 Growth Inhibition Assay Inhibition of human SNU-423 cell growth in a cell viability assay, IC50 = 0.23657 μM. SANGER
SCC-4 Growth Inhibition Assay Inhibition of human SCC-4 cell growth in a cell viability assay, IC50 = 0.23967 μM. SANGER
SF126 Growth Inhibition Assay Inhibition of human SF126 cell growth in a cell viability assay, IC50 = 0.24731 μM. SANGER
HSC-2 Growth Inhibition Assay Inhibition of human HSC-2 cell growth in a cell viability assay, IC50 = 0.24734 μM. SANGER
VA-ES-BJ Growth Inhibition Assay Inhibition of human VA-ES-BJ cell growth in a cell viability assay, IC50 = 0.24883 μM. SANGER
MHH-ES-1 Growth Inhibition Assay Inhibition of human MHH-ES-1 cell growth in a cell viability assay, IC50 = 0.2494 μM. SANGER
D-247MG Growth Inhibition Assay Inhibition of human D-247MG cell growth in a cell viability assay, IC50 = 0.25013 μM. SANGER
CCF-STTG1 Growth Inhibition Assay Inhibition of human CCF-STTG1 cell growth in a cell viability assay, IC50 = 0.25335 μM. SANGER
BFTC-905 Growth Inhibition Assay Inhibition of human BFTC-905 cell growth in a cell viability assay, IC50 = 0.25458 μM. SANGER
YT Growth Inhibition Assay Inhibition of human YT cell growth in a cell viability assay, IC50 = 0.26282 μM. SANGER
KYSE-150 Growth Inhibition Assay Inhibition of human KYSE-150 cell growth in a cell viability assay, IC50 = 0.26282 μM. SANGER
NCI-H28 Growth Inhibition Assay Inhibition of human NCI-H28 cell growth in a cell viability assay, IC50 = 0.26585 μM. SANGER
MC-IXC Growth Inhibition Assay Inhibition of human MC-IXC cell growth in a cell viability assay, IC50 = 0.26629 μM. SANGER
SW48 Growth Inhibition Assay Inhibition of human SW48 cell growth in a cell viability assay, IC50 = 0.2668 μM. SANGER
SF295 Growth Inhibition Assay Inhibition of human SF295 cell growth in a cell viability assay, IC50 = 0.27257 μM. SANGER
8505C Growth Inhibition Assay Inhibition of human 8505C cell growth in a cell viability assay, IC50 = 0.27604 μM. SANGER
ONS-76 Growth Inhibition Assay Inhibition of human ONS-76 cell growth in a cell viability assay, IC50 = 0.27841 μM. SANGER
CAL-12T Growth Inhibition Assay Inhibition of human CAL-12T cell growth in a cell viability assay, IC50 = 0.28001 μM. SANGER
MDA-MB-231 Growth Inhibition Assay Inhibition of human MDA-MB-231 cell growth in a cell viability assay, IC50 = 0.28101 μM. SANGER
GCIY Growth Inhibition Assay Inhibition of human GCIY cell growth in a cell viability assay, IC50 = 0.28692 μM. SANGER
DoTc2-4510 Growth Inhibition Assay Inhibition of human DoTc2-4510 cell growth in a cell viability assay, IC50 = 0.29002 μM. SANGER
A172 Growth Inhibition Assay Inhibition of human A172 cell growth in a cell viability assay, IC50 = 0.2915 μM. SANGER
BCPAP Growth Inhibition Assay Inhibition of human BCPAP cell growth in a cell viability assay, IC50 = 0.29879 μM. SANGER
LB831-BLC Growth Inhibition Assay Inhibition of human LB831-BLC cell growth in a cell viability assay, IC50 = 0.29946 μM. SANGER
COLO-792 Growth Inhibition Assay Inhibition of human COLO-792 cell growth in a cell viability assay, IC50 = 0.29972 μM. SANGER
BFTC-909 Growth Inhibition Assay Inhibition of human BFTC-909 cell growth in a cell viability assay, IC50 = 0.3107 μM. SANGER
KYSE-410 Growth Inhibition Assay Inhibition of human KYSE-410 cell growth in a cell viability assay, IC50 = 0.31254 μM. SANGER
EW-16 Growth Inhibition Assay Inhibition of human EW-16 cell growth in a cell viability assay, IC50 = 0.3143 μM. SANGER
SK-MES-1 Growth Inhibition Assay Inhibition of human SK-MES-1 cell growth in a cell viability assay, IC50 = 0.31485 μM. SANGER
DU-145 Growth Inhibition Assay Inhibition of human DU-145 cell growth in a cell viability assay, IC50 = 0.31889 μM. SANGER
GI-1 Growth Inhibition Assay Inhibition of human GI-1 cell growth in a cell viability assay, IC50 = 0.31902 μM. SANGER
AN3-CA Growth Inhibition Assay Inhibition of human AN3-CA cell growth in a cell viability assay, IC50 = 0.32198 μM. SANGER
EW-18 Growth Inhibition Assay Inhibition of human EW-18 cell growth in a cell viability assay, IC50 = 0.32233 μM. SANGER
NCI-H2122 Growth Inhibition Assay Inhibition of human NCI-H2122 cell growth in a cell viability assay, IC50 = 0.32285 μM. SANGER
BB30-HNC Growth Inhibition Assay Inhibition of human BB30-HNC cell growth in a cell viability assay, IC50 = 0.32367 μM. SANGER
DMS-273 Growth Inhibition Assay Inhibition of human DMS-273 cell growth in a cell viability assay, IC50 = 0.32388 μM. SANGER
SK-UT-1 Growth Inhibition Assay Inhibition of human SK-UT-1 cell growth in a cell viability assay, IC50 = 0.32952 μM. SANGER
LXF-289 Growth Inhibition Assay Inhibition of human LXF-289 cell growth in a cell viability assay, IC50 = 0.32965 μM. SANGER
NCI-H1792 Growth Inhibition Assay Inhibition of human NCI-H1792 cell growth in a cell viability assay, IC50 = 0.33096 μM. SANGER
ACHN Growth Inhibition Assay Inhibition of human ACHN cell growth in a cell viability assay, IC50 = 0.33117 μM. SANGER
D-392MG Growth Inhibition Assay Inhibition of human D-392MG cell growth in a cell viability assay, IC50 = 0.3312 μM. SANGER
MCF7 Growth Inhibition Assay Inhibition of human MCF7 cell growth in a cell viability assay, IC50 = 0.33274 μM. SANGER
HCT-15 Growth Inhibition Assay Inhibition of human HCT-15 cell growth in a cell viability assay, IC50 = 0.33432 μM. SANGER
OS-RC-2 Growth Inhibition Assay Inhibition of human OS-RC-2 cell growth in a cell viability assay, IC50 = 0.33512 μM. SANGER
NCI-H358 Growth Inhibition Assay Inhibition of human NCI-H358 cell growth in a cell viability assay, IC50 = 0.33551 μM. SANGER
HLE Growth Inhibition Assay Inhibition of human HLE cell growth in a cell viability assay, IC50 = 0.33752 μM. SANGER
SW1088 Growth Inhibition Assay Inhibition of human SW1088 cell growth in a cell viability assay, IC50 = 0.33797 μM. SANGER
MRK-nu-1 Growth Inhibition Assay Inhibition of human MRK-nu-1 cell growth in a cell viability assay, IC50 = 0.3396 μM. SANGER
C-4-II Growth Inhibition Assay Inhibition of human C-4-II cell growth in a cell viability assay, IC50 = 0.34889 μM. SANGER
ST486 Growth Inhibition Assay Inhibition of human ST486 cell growth in a cell viability assay, IC50 = 0.34939 μM. SANGER
NCI-H2405 Growth Inhibition Assay Inhibition of human NCI-H2405 cell growth in a cell viability assay, IC50 = 0.35115 μM. SANGER
SK-LMS-1 Growth Inhibition Assay Inhibition of human SK-LMS-1 cell growth in a cell viability assay, IC50 = 0.35335 μM. SANGER
PANC-10-05 Growth Inhibition Assay Inhibition of human PANC-10-05 cell growth in a cell viability assay, IC50 = 0.35633 μM. SANGER
K5 Growth Inhibition Assay Inhibition of human K5 cell growth in a cell viability assay, IC50 = 0.36149 μM. SANGER
SR Growth Inhibition Assay Inhibition of human SR cell growth in a cell viability assay, IC50 = 0.36571 μM. SANGER
Calu-3 Growth Inhibition Assay Inhibition of human Calu-3 cell growth in a cell viability assay, IC50 = 0.36825 μM. SANGER
VMRC-RCZ Growth Inhibition Assay Inhibition of human VMRC-RCZ cell growth in a cell viability assay, IC50 = 0.36935 μM. SANGER
COR-L105 Growth Inhibition Assay Inhibition of human COR-L105 cell growth in a cell viability assay, IC50 = 0.37071 μM. SANGER
ETK-1 Growth Inhibition Assay Inhibition of human ETK-1 cell growth in a cell viability assay, IC50 = 0.37693 μM. SANGER
GT3TKB Growth Inhibition Assay Inhibition of human GT3TKB cell growth in a cell viability assay, IC50 = 0.38043 μM. SANGER
PF-382 Growth Inhibition Assay Inhibition of human PF-382 cell growth in a cell viability assay, IC50 = 0.38756 μM. SANGER
HT-144 Growth Inhibition Assay Inhibition of human HT-144 cell growth in a cell viability assay, IC50 = 0.38948 μM. SANGER
TK10 Growth Inhibition Assay Inhibition of human TK10 cell growth in a cell viability assay, IC50 = 0.39144 μM. SANGER
IGR-1 Growth Inhibition Assay Inhibition of human IGR-1 cell growth in a cell viability assay, IC50 = 0.39369 μM. SANGER
SF268 Growth Inhibition Assay Inhibition of human SF268 cell growth in a cell viability assay, IC50 = 0.39381 μM. SANGER
L-540 Growth Inhibition Assay Inhibition of human L-540 cell growth in a cell viability assay, IC50 = 0.39454 μM. SANGER
SK-MEL-30 Growth Inhibition Assay Inhibition of human SK-MEL-30 cell growth in a cell viability assay, IC50 = 0.39913 μM. SANGER
KYSE-520 Growth Inhibition Assay Inhibition of human KYSE-520 cell growth in a cell viability assay, IC50 = 0.40238 μM. SANGER
RXF393 Growth Inhibition Assay Inhibition of human RXF393 cell growth in a cell viability assay, IC50 = 0.40604 μM. SANGER
A704 Growth Inhibition Assay Inhibition of human A704 cell growth in a cell viability assay, IC50 = 0.40917 μM. SANGER
HCE-4 Growth Inhibition Assay Inhibition of human HCE-4 cell growth in a cell viability assay, IC50 = 0.4101 μM. SANGER
SW780 Growth Inhibition Assay Inhibition of human SW780 cell growth in a cell viability assay, IC50 = 0.41142 μM. SANGER
TUR Growth Inhibition Assay Inhibition of human TUR cell growth in a cell viability assay, IC50 = 0.41374 μM. SANGER
D-263MG Growth Inhibition Assay Inhibition of human D-263MG cell growth in a cell viability assay, IC50 = 0.41413 μM. SANGER
NCI-H1563 Growth Inhibition Assay Inhibition of human NCI-H1563 cell growth in a cell viability assay, IC50 = 0.41484 μM. SANGER
MZ1-PC Growth Inhibition Assay Inhibition of human MZ1-PC cell growth in a cell viability assay, IC50 = 0.41783 μM. SANGER
MKN45 Growth Inhibition Assay Inhibition of human MKN45 cell growth in a cell viability assay, IC50 = 0.41931 μM. SANGER
MDA-MB-157 Growth Inhibition Assay Inhibition of human MDA-MB-157 cell growth in a cell viability assay, IC50 = 0.42015 μM. SANGER
RKO Growth Inhibition Assay Inhibition of human RKO cell growth in a cell viability assay, IC50 = 0.42017 μM. SANGER
NCI-H522 Growth Inhibition Assay Inhibition of human NCI-H522 cell growth in a cell viability assay, IC50 = 0.423 μM. SANGER
ECC12 Growth Inhibition Assay Inhibition of human ECC12 cell growth in a cell viability assay, IC50 = 0.42923 μM. SANGER
COLO-205 Growth Inhibition Assay Inhibition of human COLO-205 cell growth in a cell viability assay, IC50 = 0.43222 μM. SANGER
EW-13 Growth Inhibition Assay Inhibition of human EW-13 cell growth in a cell viability assay, IC50 = 0.43548 μM. SANGER
CAL-39 Growth Inhibition Assay Inhibition of human CAL-39 cell growth in a cell viability assay, IC50 = 0.43719 μM. SANGER
MPP-89 Growth Inhibition Assay Inhibition of human MPP-89 cell growth in a cell viability assay, IC50 = 0.43945 μM. SANGER
SK-LU-1 Growth Inhibition Assay Inhibition of human SK-LU-1 cell growth in a cell viability assay, IC50 = 0.43985 μM. SANGER
HuO9 Growth Inhibition Assay Inhibition of human HuO9 cell growth in a cell viability assay, IC50 = 0.44135 μM. SANGER
NCI-H2170 Growth Inhibition Assay Inhibition of human NCI-H2170 cell growth in a cell viability assay, IC50 = 0.44353 μM. SANGER
HOS Growth Inhibition Assay Inhibition of human HOS cell growth in a cell viability assay, IC50 = 0.45888 μM. SANGER
CCRF-CEM Growth Inhibition Assay Inhibition of human CCRF-CEM cell growth in a cell viability assay, IC50 = 0.47081 μM. SANGER
COLO-680N Growth Inhibition Assay Inhibition of human COLO-680N cell growth in a cell viability assay, IC50 = 0.47106 μM. SANGER
786-0 Growth Inhibition Assay Inhibition of human 786-0 cell growth in a cell viability assay, IC50 = 0.47344 μM. SANGER
EFE-184 Growth Inhibition Assay Inhibition of human EFE-184 cell growth in a cell viability assay, IC50 = 0.47346 μM. SANGER
A2780 Growth Inhibition Assay Inhibition of human A2780 cell growth in a cell viability assay, IC50 = 0.47503 μM. SANGER
A498 Growth Inhibition Assay Inhibition of human A498 cell growth in a cell viability assay, IC50 = 0.47693 μM. SANGER
KYSE-180 Growth Inhibition Assay Inhibition of human KYSE-180 cell growth in a cell viability assay, IC50 = 0.47825 μM. SANGER
SIG-M5 Growth Inhibition Assay Inhibition of human SIG-M5 cell growth in a cell viability assay, IC50 = 0.48299 μM. SANGER
NCI-H2009 Growth Inhibition Assay Inhibition of human NCI-H2009 cell growth in a cell viability assay, IC50 = 0.48689 μM. SANGER
BC-3 Growth Inhibition Assay Inhibition of human BC-3 cell growth in a cell viability assay, IC50 = 0.48741 μM. SANGER
MEL-JUSO Growth Inhibition Assay Inhibition of human MEL-JUSO cell growth in a cell viability assay, IC50 = 0.49214 μM. SANGER
SH-4 Growth Inhibition Assay Inhibition of human SH-4 cell growth in a cell viability assay, IC50 = 0.49271 μM. SANGER
SNG-M Growth Inhibition Assay Inhibition of human SNG-M cell growth in a cell viability assay, IC50 = 0.49283 μM. SANGER
BxPC-3 Growth Inhibition Assay Inhibition of human BxPC-3 cell growth in a cell viability assay, IC50 = 0.49366 μM. SANGER
HCC38 Growth Inhibition Assay Inhibition of human HCC38 cell growth in a cell viability assay, IC50 = 0.49828 μM. SANGER
SK-HEP-1 Growth Inhibition Assay Inhibition of human SK-HEP-1 cell growth in a cell viability assay, IC50 = 0.51297 μM. SANGER
REH Growth Inhibition Assay Inhibition of human REH cell growth in a cell viability assay, IC50 = 0.51334 μM. SANGER
NCI-H1299 Growth Inhibition Assay Inhibition of human NCI-H1299 cell growth in a cell viability assay, IC50 = 0.51572 μM. SANGER
SK-CO-1 Growth Inhibition Assay Inhibition of human SK-CO-1 cell growth in a cell viability assay, IC50 = 0.51849 μM. SANGER
EFO-27 Growth Inhibition Assay Inhibition of human EFO-27 cell growth in a cell viability assay, IC50 = 0.52524 μM. SANGER
A2058 Growth Inhibition Assay Inhibition of human A2058 cell growth in a cell viability assay, IC50 = 0.52844 μM. SANGER
GCT Growth Inhibition Assay Inhibition of human GCT cell growth in a cell viability assay, IC50 = 0.52897 μM. SANGER
EW-1 Growth Inhibition Assay Inhibition of human EW-1 cell growth in a cell viability assay, IC50 = 0.53155 μM. SANGER
PC-14 Growth Inhibition Assay Inhibition of human PC-14 cell growth in a cell viability assay, IC50 = 0.53855 μM. SANGER
KG-1 Growth Inhibition Assay Inhibition of human KG-1 cell growth in a cell viability assay, IC50 = 0.55419 μM. SANGER
LU-99A Growth Inhibition Assay Inhibition of human LU-99A cell growth in a cell viability assay, IC50 = 0.55849 μM. SANGER
DEL Growth Inhibition Assay Inhibition of human DEL cell growth in a cell viability assay, IC50 = 0.55898 μM. SANGER
GB-1 Growth Inhibition Assay Inhibition of human GB-1 cell growth in a cell viability assay, IC50 = 0.56007 μM. SANGER
A4-Fuk Growth Inhibition Assay Inhibition of human A4-Fuk cell growth in a cell viability assay, IC50 = 0.56048 μM. SANGER
A375 Growth Inhibition Assay Inhibition of human A375 cell growth in a cell viability assay, IC50 = 0.56103 μM. SANGER
CAL-85-1 Growth Inhibition Assay Inhibition of human CAL-85-1 cell growth in a cell viability assay, IC50 = 0.56518 μM. SANGER
BC-1 Growth Inhibition Assay Inhibition of human BC-1 cell growth in a cell viability assay, IC50 = 0.56558 μM. SANGER
SCC-15 Growth Inhibition Assay Inhibition of human SCC-15 cell growth in a cell viability assay, IC50 = 0.57407 μM. SANGER
RPMI-8402 Growth Inhibition Assay Inhibition of human RPMI-8402 cell growth in a cell viability assay, IC50 = 0.57766 μM. SANGER
OAW-42 Growth Inhibition Assay Inhibition of human OAW-42 cell growth in a cell viability assay, IC50 = 0.58091 μM. SANGER
A101D Growth Inhibition Assay Inhibition of human A101D cell growth in a cell viability assay, IC50 = 0.58789 μM. SANGER
RPMI-7951 Growth Inhibition Assay Inhibition of human RPMI-7951 cell growth in a cell viability assay, IC50 = 0.61123 μM. SANGER
TE-12 Growth Inhibition Assay Inhibition of human TE-12 cell growth in a cell viability assay, IC50 = 0.61199 μM. SANGER
P30-OHK Growth Inhibition Assay Inhibition of human P30-OHK cell growth in a cell viability assay, IC50 = 0.61246 μM. SANGER
KP-4 Growth Inhibition Assay Inhibition of human KP-4 cell growth in a cell viability assay, IC50 = 0.61585 μM. SANGER
U251 Growth Inhibition Assay Inhibition of human U251 cell growth in a cell viability assay, IC50 = 0.61621 μM. SANGER
RS4-11 Growth Inhibition Assay Inhibition of human RS4-11 cell growth in a cell viability assay, IC50 = 0.62417 μM. SANGER
CA46 Growth Inhibition Assay Inhibition of human CA46 cell growth in a cell viability assay, IC50 = 0.62885 μM. SANGER
DOK Growth Inhibition Assay Inhibition of human DOK cell growth in a cell viability assay, IC50 = 0.6367 μM. SANGER
NCI-H2126 Growth Inhibition Assay Inhibition of human NCI-H2126 cell growth in a cell viability assay, IC50 = 0.64325 μM. SANGER
CaR-1 Growth Inhibition Assay Inhibition of human CaR-1 cell growth in a cell viability assay, IC50 = 0.64476 μM. SANGER
ACN Growth Inhibition Assay Inhibition of human ACN cell growth in a cell viability assay, IC50 = 0.64832 μM. SANGER
SUP-T1 Growth Inhibition Assay Inhibition of human SUP-T1 cell growth in a cell viability assay, IC50 = 0.65424 μM. SANGER
KALS-1 Growth Inhibition Assay Inhibition of human KALS-1 cell growth in a cell viability assay, IC50 = 0.65903 μM. SANGER
697 Growth Inhibition Assay Inhibition of human 697 cell growth in a cell viability assay, IC50 = 0.67132 μM. SANGER
NCI-H2087 Growth Inhibition Assay Inhibition of human NCI-H2087 cell growth in a cell viability assay, IC50 = 0.67782 μM. SANGER
NCI-H1355 Growth Inhibition Assay Inhibition of human NCI-H1355 cell growth in a cell viability assay, IC50 = 0.67816 μM. SANGER
EW-7 Growth Inhibition Assay Inhibition of human EW-7 cell growth in a cell viability assay, IC50 = 0.68195 μM. SANGER
OVCAR-5 Growth Inhibition Assay Inhibition of human OVCAR-5 cell growth in a cell viability assay, IC50 = 0.69167 μM. SANGER
HOP-92 Growth Inhibition Assay Inhibition of human HOP-92 cell growth in a cell viability assay, IC50 = 0.69865 μM. SANGER
NCI-H2052 Growth Inhibition Assay Inhibition of human NCI-H2052 cell growth in a cell viability assay, IC50 = 0.69894 μM. SANGER
NCI-H1703 Growth Inhibition Assay Inhibition of human NCI-H1703 cell growth in a cell viability assay, IC50 = 0.70473 μM. SANGER
NCI-H719 Growth Inhibition Assay Inhibition of human NCI-H719 cell growth in a cell viability assay, IC50 = 0.70676 μM. SANGER
MC116 Growth Inhibition Assay Inhibition of human MC116 cell growth in a cell viability assay, IC50 = 0.71581 μM. SANGER
NCI-H526 Growth Inhibition Assay Inhibition of human NCI-H526 cell growth in a cell viability assay, IC50 = 0.71925 μM. SANGER
MEL-HO Growth Inhibition Assay Inhibition of human MEL-HO cell growth in a cell viability assay, IC50 = 0.72664 μM. SANGER
AM-38 Growth Inhibition Assay Inhibition of human AM-38 cell growth in a cell viability assay, IC50 = 0.72871 μM. SANGER
SW1783 Growth Inhibition Assay Inhibition of human SW1783 cell growth in a cell viability assay, IC50 = 0.73337 μM. SANGER
NB69 Growth Inhibition Assay Inhibition of human NB69 cell growth in a cell viability assay, IC50 = 0.73467 μM. SANGER
VM-CUB-1 Growth Inhibition Assay Inhibition of human VM-CUB-1 cell growth in a cell viability assay, IC50 = 0.7367 μM. SANGER
LCLC-97TM1 Growth Inhibition Assay Inhibition of human LCLC-97TM1 cell growth in a cell viability assay, IC50 = 0.75396 μM. SANGER
NCCIT Growth Inhibition Assay Inhibition of human NCCIT cell growth in a cell viability assay, IC50 = 0.76775 μM. SANGER
SNB75 Growth Inhibition Assay Inhibition of human SNB75 cell growth in a cell viability assay, IC50 = 0.77311 μM. SANGER
NCI-H292 Growth Inhibition Assay Inhibition of human NCI-H292 cell growth in a cell viability assay, IC50 = 0.77393 μM. SANGER
NCI-H1734 Growth Inhibition Assay Inhibition of human NCI-H1734 cell growth in a cell viability assay, IC50 = 0.77483 μM. SANGER
KYSE-510 Growth Inhibition Assay Inhibition of human KYSE-510 cell growth in a cell viability assay, IC50 = 0.78539 μM. SANGER
RL95-2 Growth Inhibition Assay Inhibition of human RL95-2 cell growth in a cell viability assay, IC50 = 0.79572 μM. SANGER
ML-2 Growth Inhibition Assay Inhibition of human ML-2 cell growth in a cell viability assay, IC50 = 0.79859 μM. SANGER
NCI-H1793 Growth Inhibition Assay Inhibition of human NCI-H1793 cell growth in a cell viability assay, IC50 = 0.80088 μM. SANGER
LOUCY Growth Inhibition Assay Inhibition of human LOUCY cell growth in a cell viability assay, IC50 = 0.805 μM. SANGER
KYSE-70 Growth Inhibition Assay Inhibition of human KYSE-70 cell growth in a cell viability assay, IC50 = 0.82041 μM. SANGER
NB13 Growth Inhibition Assay Inhibition of human NB13 cell growth in a cell viability assay, IC50 = 0.82057 μM. SANGER
A3-KAW Growth Inhibition Assay Inhibition of human A3-KAW cell growth in a cell viability assay, IC50 = 0.83993 μM. SANGER
GR-ST Growth Inhibition Assay Inhibition of human GR-ST cell growth in a cell viability assay, IC50 = 0.87237 μM. SANGER
SCC-9 Growth Inhibition Assay Inhibition of human SCC-9 cell growth in a cell viability assay, IC50 = 0.87286 μM. SANGER
HCC1599 Growth Inhibition Assay Inhibition of human HCC1599 cell growth in a cell viability assay, IC50 = 0.8791 μM. SANGER
MKN1 Growth Inhibition Assay Inhibition of human MKN1 cell growth in a cell viability assay, IC50 = 0.88412 μM. SANGER
NCI-H1650 Growth Inhibition Assay Inhibition of human NCI-H1650 cell growth in a cell viability assay, IC50 = 0.88916 μM. SANGER
LS-1034 Growth Inhibition Assay Inhibition of human LS-1034 cell growth in a cell viability assay, IC50 = 0.90528 μM. SANGER
639-V Growth Inhibition Assay Inhibition of human 639-V cell growth in a cell viability assay, IC50 = 0.92063 μM. SANGER
BL-41 Growth Inhibition Assay Inhibition of human BL-41 cell growth in a cell viability assay, IC50 = 0.92539 μM. SANGER
HT-1376 Growth Inhibition Assay Inhibition of human HT-1376 cell growth in a cell viability assay, IC50 = 0.92918 μM. SANGER
CAL-62 Growth Inhibition Assay Inhibition of human CAL-62 cell growth in a cell viability assay, IC50 = 0.93235 μM. SANGER
DBTRG-05MG Growth Inhibition Assay Inhibition of human DBTRG-05MG cell growth in a cell viability assay, IC50 = 0.94197 μM. SANGER
SW872 Growth Inhibition Assay Inhibition of human SW872 cell growth in a cell viability assay, IC50 = 0.94459 μM. SANGER
RT-112 Growth Inhibition Assay Inhibition of human RT-112 cell growth in a cell viability assay, IC50 = 0.97483 μM. SANGER
HT-29 Growth Inhibition Assay Inhibition of human HT-29 cell growth in a cell viability assay, IC50 = 0.97996 μM. SANGER
U-266 Growth Inhibition Assay Inhibition of human U-266 cell growth in a cell viability assay, IC50 = 0.98302 μM. SANGER
HEL Growth Inhibition Assay Inhibition of human HEL cell growth in a cell viability assay, IC50 = 0.98517 μM. SANGER
LB2241-RCC Growth Inhibition Assay Inhibition of human LB2241-RCC cell growth in a cell viability assay, IC50 = 0.98707 μM. SANGER
TE-441-T Growth Inhibition Assay Inhibition of human TE-441-T cell growth in a cell viability assay, IC50 = 0.99434 μM. SANGER
UM-UC-3 Growth Inhibition Assay Inhibition of human UM-UC-3 cell growth in a cell viability assay, IC50 = 1.00689 μM. SANGER
DSH1 Growth Inhibition Assay Inhibition of human DSH1 cell growth in a cell viability assay, IC50 = 1.02389 μM. SANGER
SCC-25 Growth Inhibition Assay Inhibition of human SCC-25 cell growth in a cell viability assay, IC50 = 1.04887 μM. SANGER
OAW-28 Growth Inhibition Assay Inhibition of human OAW-28 cell growth in a cell viability assay, IC50 = 1.0569 μM. SANGER
TE-11 Growth Inhibition Assay Inhibition of human TE-11 cell growth in a cell viability assay, IC50 = 1.07154 μM. SANGER
RD Growth Inhibition Assay Inhibition of human RD cell growth in a cell viability assay, IC50 = 1.07208 μM. SANGER
ESS-1 Growth Inhibition Assay Inhibition of human ESS-1 cell growth in a cell viability assay, IC50 = 1.07618 μM. SANGER
CMK Growth Inhibition Assay Inhibition of human CMK cell growth in a cell viability assay, IC50 = 1.09082 μM. SANGER
KURAMOCHI Growth Inhibition Assay Inhibition of human KURAMOCHI cell growth in a cell viability assay, IC50 = 1.10935 μM. SANGER
KU812 Growth Inhibition Assay Inhibition of human KU812 cell growth in a cell viability assay, IC50 = 1.11164 μM. SANGER
COLO-668 Growth Inhibition Assay Inhibition of human COLO-668 cell growth in a cell viability assay, IC50 = 1.12232 μM. SANGER
KYSE-140 Growth Inhibition Assay Inhibition of human KYSE-140 cell growth in a cell viability assay, IC50 = 1.14444 μM. SANGER
NCI-H716 Growth Inhibition Assay Inhibition of human NCI-H716 cell growth in a cell viability assay, IC50 = 1.15487 μM. SANGER
ES4 Growth Inhibition Assay Inhibition of human ES4 cell growth in a cell viability assay, IC50 = 1.16462 μM. SANGER
SW626 Growth Inhibition Assay Inhibition of human SW626 cell growth in a cell viability assay, IC50 = 1.16813 μM. SANGER
U-2-OS Growth Inhibition Assay Inhibition of human U-2-OS cell growth in a cell viability assay, IC50 = 1.16996 μM. SANGER
HCC1569 Growth Inhibition Assay Inhibition of human HCC1569 cell growth in a cell viability assay, IC50 = 1.17018 μM. SANGER
A673 Growth Inhibition Assay Inhibition of human A673 cell growth in a cell viability assay, IC50 = 1.17069 μM. SANGER
GAMG Growth Inhibition Assay Inhibition of human GAMG cell growth in a cell viability assay, IC50 = 1.17866 μM. SANGER
FADU Growth Inhibition Assay Inhibition of human FADU cell growth in a cell viability assay, IC50 = 1.18547 μM. SANGER
MKN28 Growth Inhibition Assay Inhibition of human MKN28 cell growth in a cell viability assay, IC50 = 1.19816 μM. SANGER
DB Growth Inhibition Assay Inhibition of human DB cell growth in a cell viability assay, IC50 = 1.21929 μM. SANGER
ES8 Growth Inhibition Assay Inhibition of human ES8 cell growth in a cell viability assay, IC50 = 1.22304 μM. SANGER
OVCAR-3 Growth Inhibition Assay Inhibition of human OVCAR-3 cell growth in a cell viability assay, IC50 = 1.22696 μM. SANGER
SW954 Growth Inhibition Assay Inhibition of human SW954 cell growth in a cell viability assay, IC50 = 1.25911 μM. SANGER
ECC4 Growth Inhibition Assay Inhibition of human ECC4 cell growth in a cell viability assay, IC50 = 1.26182 μM. SANGER
SK-MEL-3 Growth Inhibition Assay Inhibition of human SK-MEL-3 cell growth in a cell viability assay, IC50 = 1.26372 μM. SANGER
SBC-5 Growth Inhibition Assay Inhibition of human SBC-5 cell growth in a cell viability assay, IC50 = 1.27389 μM. SANGER
TE-10 Growth Inhibition Assay Inhibition of human TE-10 cell growth in a cell viability assay, IC50 = 1.2814 μM. SANGER
NCI-H630 Growth Inhibition Assay Inhibition of human NCI-H630 cell growth in a cell viability assay, IC50 = 1.28805 μM. SANGER
EGI-1 Growth Inhibition Assay Inhibition of human EGI-1 cell growth in a cell viability assay, IC50 = 1.30089 μM. SANGER
NCI-H1770 Growth Inhibition Assay Inhibition of human NCI-H1770 cell growth in a cell viability assay, IC50 = 1.31382 μM. SANGER
ES5 Growth Inhibition Assay Inhibition of human ES5 cell growth in a cell viability assay, IC50 = 1.32981 μM. SANGER
Daoy Growth Inhibition Assay Inhibition of human Daoy cell growth in a cell viability assay, IC50 = 1.3357 μM. SANGER
OCUB-M Growth Inhibition Assay Inhibition of human OCUB-M cell growth in a cell viability assay, IC50 = 1.35915 μM. SANGER
WSU-NHL Growth Inhibition Assay Inhibition of human WSU-NHL cell growth in a cell viability assay, IC50 = 1.39185 μM. SANGER
M059J Growth Inhibition Assay Inhibition of human M059J cell growth in a cell viability assay, IC50 = 1.39231 μM. SANGER
NCI-H69 Growth Inhibition Assay Inhibition of human NCI-H69 cell growth in a cell viability assay, IC50 = 1.39549 μM. SANGER
NH-12 Growth Inhibition Assay Inhibition of human NH-12 cell growth in a cell viability assay, IC50 = 1.40262 μM. SANGER
COLO-800 Growth Inhibition Assay Inhibition of human COLO-800 cell growth in a cell viability assay, IC50 = 1.4036 μM. SANGER
NB6 Growth Inhibition Assay Inhibition of human NB6 cell growth in a cell viability assay, IC50 = 1.4446 μM. SANGER
C3A Growth Inhibition Assay Inhibition of human C3A cell growth in a cell viability assay, IC50 = 1.44539 μM. SANGER
BB65-RCC Growth Inhibition Assay Inhibition of human BB65-RCC cell growth in a cell viability assay, IC50 = 1.47436 μM. SANGER
CTB-1 Growth Inhibition Assay Inhibition of human CTB-1 cell growth in a cell viability assay, IC50 = 1.486 μM. SANGER
HCC1806 Growth Inhibition Assay Inhibition of human HCC1806 cell growth in a cell viability assay, IC50 = 1.53072 μM. SANGER
TE-15 Growth Inhibition Assay Inhibition of human TE-15 cell growth in a cell viability assay, IC50 = 1.53748 μM. SANGER
GMS-10 Growth Inhibition Assay Inhibition of human GMS-10 cell growth in a cell viability assay, IC50 = 1.53837 μM. SANGER
ES7 Growth Inhibition Assay Inhibition of human ES7 cell growth in a cell viability assay, IC50 = 1.53848 μM. SANGER
RO82-W-1 Growth Inhibition Assay Inhibition of human RO82-W-1 cell growth in a cell viability assay, IC50 = 1.54406 μM. SANGER
NCI-H1522 Growth Inhibition Assay Inhibition of human NCI-H1522 cell growth in a cell viability assay, IC50 = 1.545 μM. SANGER
IST-MES1 Growth Inhibition Assay Inhibition of human IST-MES1 cell growth in a cell viability assay, IC50 = 1.56074 μM. SANGER
EM-2 Growth Inhibition Assay Inhibition of human EM-2 cell growth in a cell viability assay, IC50 = 1.56554 μM. SANGER
NUGC-3 Growth Inhibition Assay Inhibition of human NUGC-3 cell growth in a cell viability assay, IC50 = 1.56928 μM. SANGER
BOKU Growth Inhibition Assay Inhibition of human BOKU cell growth in a cell viability assay, IC50 = 1.5697 μM. SANGER
DK-MG Growth Inhibition Assay Inhibition of human DK-MG cell growth in a cell viability assay, IC50 = 1.58048 μM. SANGER
SW620 Growth Inhibition Assay Inhibition of human SW620 cell growth in a cell viability assay, IC50 = 1.61701 μM. SANGER
NCI-H1693 Growth Inhibition Assay Inhibition of human NCI-H1693 cell growth in a cell viability assay, IC50 = 1.63492 μM. SANGER
NCI-H838 Growth Inhibition Assay Inhibition of human NCI-H838 cell growth in a cell viability assay, IC50 = 1.63895 μM. SANGER
HTC-C3 Growth Inhibition Assay Inhibition of human HTC-C3 cell growth in a cell viability assay, IC50 = 1.64035 μM. SANGER
TE-6 Growth Inhibition Assay Inhibition of human TE-6 cell growth in a cell viability assay, IC50 = 1.64833 μM. SANGER
QIMR-WIL Growth Inhibition Assay Inhibition of human QIMR-WIL cell growth in a cell viability assay, IC50 = 1.65364 μM. SANGER
OPM-2 Growth Inhibition Assay Inhibition of human OPM-2 cell growth in a cell viability assay, IC50 = 1.65801 μM. SANGER
TE-8 Growth Inhibition Assay Inhibition of human TE-8 cell growth in a cell viability assay, IC50 = 1.679 μM. SANGER
MFE-296 Growth Inhibition Assay Inhibition of human MFE-296 cell growth in a cell viability assay, IC50 = 1.67951 μM. SANGER
8305C Growth Inhibition Assay Inhibition of human 8305C cell growth in a cell viability assay, IC50 = 1.68034 μM. SANGER
IGROV-1 Growth Inhibition Assay Inhibition of human IGROV-1 cell growth in a cell viability assay, IC50 = 1.69317 μM. SANGER
HCC2157 Growth Inhibition Assay Inhibition of human HCC2157 cell growth in a cell viability assay, IC50 = 1.73898 μM. SANGER
NCI-H1436 Growth Inhibition Assay Inhibition of human NCI-H1436 cell growth in a cell viability assay, IC50 = 1.74054 μM. SANGER
K052 Growth Inhibition Assay Inhibition of human K052 cell growth in a cell viability assay, IC50 = 1.74614 μM. SANGER
5637 Growth Inhibition Assay Inhibition of human 5637 cell growth in a cell viability assay, IC50 = 1.77422 μM. SANGER
NCI-H747 Growth Inhibition Assay Inhibition of human NCI-H747 cell growth in a cell viability assay, IC50 = 1.77706 μM. SANGER
UMC-11 Growth Inhibition Assay Inhibition of human UMC-11 cell growth in a cell viability assay, IC50 = 1.78278 μM. SANGER
SJRH30 Growth Inhibition Assay Inhibition of human SJRH30 cell growth in a cell viability assay, IC50 = 1.7888 μM. SANGER
HMV-II Growth Inhibition Assay Inhibition of human HMV-II cell growth in a cell viability assay, IC50 = 1.79386 μM. SANGER
HSC-3 Growth Inhibition Assay Inhibition of human HSC-3 cell growth in a cell viability assay, IC50 = 1.81675 μM. SANGER
CESS Growth Inhibition Assay Inhibition of human CESS cell growth in a cell viability assay, IC50 = 1.8191 μM. SANGER
MN-60 Growth Inhibition Assay Inhibition of human MN-60 cell growth in a cell viability assay, IC50 = 1.83489 μM. SANGER
OVCAR-4 Growth Inhibition Assay Inhibition of human OVCAR-4 cell growth in a cell viability assay, IC50 = 1.8477 μM. SANGER
RCC10RGB Growth Inhibition Assay Inhibition of human RCC10RGB cell growth in a cell viability assay, IC50 = 1.85868 μM. SANGER
Caov-4 Growth Inhibition Assay Inhibition of human Caov-4 cell growth in a cell viability assay, IC50 = 1.91696 μM. SANGER
T-24 Growth Inhibition Assay Inhibition of human T-24 cell growth in a cell viability assay, IC50 = 1.91893 μM. SANGER
HCE-T Growth Inhibition Assay Inhibition of human HCE-T cell growth in a cell viability assay, IC50 = 1.93451 μM. SANGER
NCI-H1618 Growth Inhibition Assay Inhibition of human NCI-H1618 cell growth in a cell viability assay, IC50 = 1.95521 μM. SANGER
GOTO Growth Inhibition Assay Inhibition of human GOTO cell growth in a cell viability assay, IC50 = 1.95832 μM. SANGER
CTV-1 Growth Inhibition Assay Inhibition of human CTV-1 cell growth in a cell viability assay, IC50 = 2.01635 μM. SANGER
NCI-H661 Growth Inhibition Assay Inhibition of human NCI-H661 cell growth in a cell viability assay, IC50 = 2.02361 μM. SANGER
OVCAR-8 Growth Inhibition Assay Inhibition of human OVCAR-8 cell growth in a cell viability assay, IC50 = 2.0315 μM. SANGER
OCI-AML2 Growth Inhibition Assay Inhibition of human OCI-AML2 cell growth in a cell viability assay, IC50 = 2.07476 μM. SANGER
GP5d Growth Inhibition Assay Inhibition of human GP5d cell growth in a cell viability assay, IC50 = 2.07534 μM. SANGER
IM-9 Growth Inhibition Assay Inhibition of human IM-9 cell growth in a cell viability assay, IC50 = 2.10517 μM. SANGER
Calu-1 Growth Inhibition Assay Inhibition of human Calu-1 cell growth in a cell viability assay, IC50 = 2.12405 μM. SANGER
LC-1F Growth Inhibition Assay Inhibition of human LC-1F cell growth in a cell viability assay, IC50 = 2.14764 μM. SANGER
NEC8 Growth Inhibition Assay Inhibition of human NEC8 cell growth in a cell viability assay, IC50 = 2.15601 μM. SANGER
SK-MM-2 Growth Inhibition Assay Inhibition of human SK-MM-2 cell growth in a cell viability assay, IC50 = 2.17622 μM. SANGER
BHT-101 Growth Inhibition Assay Inhibition of human BHT-101 cell growth in a cell viability assay, IC50 = 2.19654 μM. SANGER
IST-MEL1 Growth Inhibition Assay Inhibition of human IST-MEL1 cell growth in a cell viability assay, IC50 = 2.2183 μM. SANGER
NCI-H1648 Growth Inhibition Assay Inhibition of human NCI-H1648 cell growth in a cell viability assay, IC50 = 2.23428 μM. SANGER
DV-90 Growth Inhibition Assay Inhibition of human DV-90 cell growth in a cell viability assay, IC50 = 2.24215 μM. SANGER
CAPAN-1 Growth Inhibition Assay Inhibition of human CAPAN-1 cell growth in a cell viability assay, IC50 = 2.24787 μM. SANGER
C-33-A Growth Inhibition Assay Inhibition of human C-33-A cell growth in a cell viability assay, IC50 = 2.26063 μM. SANGER
SW1573 Growth Inhibition Assay Inhibition of human SW1573 cell growth in a cell viability assay, IC50 = 2.28472 μM. SANGER
NCI-H1304 Growth Inhibition Assay Inhibition of human NCI-H1304 cell growth in a cell viability assay, IC50 = 2.28867 μM. SANGER
RCM-1 Growth Inhibition Assay Inhibition of human RCM-1 cell growth in a cell viability assay, IC50 = 2.29298 μM. SANGER
KINGS-1 Growth Inhibition Assay Inhibition of human KINGS-1 cell growth in a cell viability assay, IC50 = 2.30271 μM. SANGER
Hs-578-T Growth Inhibition Assay Inhibition of human Hs-578-T cell growth in a cell viability assay, IC50 = 2.30709 μM. SANGER
KLE Growth Inhibition Assay Inhibition of human KLE cell growth in a cell viability assay, IC50 = 2.30734 μM. SANGER
BHY Growth Inhibition Assay Inhibition of human BHY cell growth in a cell viability assay, IC50 = 2.34912 μM. SANGER
WM-115 Growth Inhibition Assay Inhibition of human WM-115 cell growth in a cell viability assay, IC50 = 2.35968 μM. SANGER
JiyoyeP-2003 Growth Inhibition Assay Inhibition of human JiyoyeP-2003 cell growth in a cell viability assay, IC50 = 2.36405 μM. SANGER
NCI-H2228 Growth Inhibition Assay Inhibition of human NCI-H2228 cell growth in a cell viability assay, IC50 = 2.38384 μM. SANGER
NCI-H226 Growth Inhibition Assay Inhibition of human NCI-H226 cell growth in a cell viability assay, IC50 = 2.38663 μM. SANGER
HCC70 Growth Inhibition Assay Inhibition of human HCC70 cell growth in a cell viability assay, IC50 = 2.44949 μM. SANGER
SK-PN-DW Growth Inhibition Assay Inhibition of human SK-PN-DW cell growth in a cell viability assay, IC50 = 2.46029 μM. SANGER
KYSE-450 Growth Inhibition Assay Inhibition of human KYSE-450 cell growth in a cell viability assay, IC50 = 2.59202 μM. SANGER
SN12C Growth Inhibition Assay Inhibition of human SN12C cell growth in a cell viability assay, IC50 = 2.6275 μM. SANGER
U-87-MG Growth Inhibition Assay Inhibition of human U-87-MG cell growth in a cell viability assay, IC50 = 2.68124 μM. SANGER
Becker Growth Inhibition Assay Inhibition of human Becker cell growth in a cell viability assay, IC50 = 2.69475 μM. SANGER
NCI-SNU-1 Growth Inhibition Assay Inhibition of human NCI-SNU-1 cell growth in a cell viability assay, IC50 = 2.70325 μM. SANGER
IST-SL1 Growth Inhibition Assay Inhibition of human IST-SL1 cell growth in a cell viability assay, IC50 = 2.70327 μM. SANGER
SIMA Growth Inhibition Assay Inhibition of human SIMA cell growth in a cell viability assay, IC50 = 2.7086 μM. SANGER
IMR-5 Growth Inhibition Assay Inhibition of human IMR-5 cell growth in a cell viability assay, IC50 = 2.71465 μM. SANGER
COLO-678 Growth Inhibition Assay Inhibition of human COLO-678 cell growth in a cell viability assay, IC50 = 2.73477 μM. SANGER
LS-411N Growth Inhibition Assay Inhibition of human LS-411N cell growth in a cell viability assay, IC50 = 2.74999 μM. SANGER
Capan-2 Growth Inhibition Assay Inhibition of human Capan-2 cell growth in a cell viability assay, IC50 = 2.7664 μM. SANGER
HT55 Growth Inhibition Assay Inhibition of human HT55 cell growth in a cell viability assay, IC50 = 2.77321 μM. SANGER
RPMI-2650 Growth Inhibition Assay Inhibition of human RPMI-2650 cell growth in a cell viability assay, IC50 = 2.78633 μM. SANGER
HuH-7 Growth Inhibition Assay Inhibition of human HuH-7 cell growth in a cell viability assay, IC50 = 2.78923 μM. SANGER
NCI-H2452 Growth Inhibition Assay Inhibition of human NCI-H2452 cell growth in a cell viability assay, IC50 = 2.80514 μM. SANGER
RMG-I Growth Inhibition Assay Inhibition of human RMG-I cell growth in a cell viability assay, IC50 = 2.86407 μM. SANGER
NCI-H2347 Growth Inhibition Assay Inhibition of human NCI-H2347 cell growth in a cell viability assay, IC50 = 2.86973 μM. SANGER
COLO-824 Growth Inhibition Assay Inhibition of human COLO-824 cell growth in a cell viability assay, IC50 = 2.88433 μM. SANGER
HC-1 Growth Inhibition Assay Inhibition of human HC-1 cell growth in a cell viability assay, IC50 = 2.89529 μM. SANGER
ChaGo-K-1 Growth Inhibition Assay Inhibition of human ChaGo-K-1 cell growth in a cell viability assay, IC50 = 2.89815 μM. SANGER
Ramos-2G6-4C10 Growth Inhibition Assay Inhibition of human Ramos-2G6-4C10 cell growth in a cell viability assay, IC50 = 2.94387 μM. SANGER
SK-MEL-2 Growth Inhibition Assay Inhibition of human SK-MEL-2 cell growth in a cell viability assay, IC50 = 2.97003 μM. SANGER
NCI-H64 Growth Inhibition Assay Inhibition of human NCI-H64 cell growth in a cell viability assay, IC50 = 3.00372 μM. SANGER
MHH-NB-11 Growth Inhibition Assay Inhibition of human MHH-NB-11 cell growth in a cell viability assay, IC50 = 3.01878 μM. SANGER
SU-DHL-1 Growth Inhibition Assay Inhibition of human SU-DHL-1 cell growth in a cell viability assay, IC50 = 3.06959 μM. SANGER
NOS-1 Growth Inhibition Assay Inhibition of human NOS-1 cell growth in a cell viability assay, IC50 = 3.09872 μM. SANGER
ARH-77 Growth Inhibition Assay Inhibition of human ARH-77 cell growth in a cell viability assay, IC50 = 3.14605 μM. SANGER
HO-1-N-1 Growth Inhibition Assay Inhibition of human HO-1-N-1 cell growth in a cell viability assay, IC50 = 3.15569 μM. SANGER
TGBC1TKB Growth Inhibition Assay Inhibition of human TGBC1TKB cell growth in a cell viability assay, IC50 = 3.17557 μM. SANGER
HuP-T3 Growth Inhibition Assay Inhibition of human HuP-T3 cell growth in a cell viability assay, IC50 = 3.2079 μM. SANGER
BEN Growth Inhibition Assay Inhibition of human BEN cell growth in a cell viability assay, IC50 = 3.21481 μM. SANGER
HGC-27 Growth Inhibition Assay Inhibition of human HGC-27 cell growth in a cell viability assay, IC50 = 3.2299 μM. SANGER
no-11 Growth Inhibition Assay Inhibition of human no-11 cell growth in a cell viability assay, IC50 = 3.23209 μM. SANGER
NCI-H460 Growth Inhibition Assay Inhibition of human NCI-H460 cell growth in a cell viability assay, IC50 = 3.26306 μM. SANGER
COLO-684 Growth Inhibition Assay Inhibition of human COLO-684 cell growth in a cell viability assay, IC50 = 3.34745 μM. SANGER
RPMI-6666 Growth Inhibition Assay Inhibition of human RPMI-6666 cell growth in a cell viability assay, IC50 = 3.41159 μM. SANGER
NCI-H1993 Growth Inhibition Assay Inhibition of human NCI-H1993 cell growth in a cell viability assay, IC50 = 3.53667 μM. SANGER
IPC-298 Growth Inhibition Assay Inhibition of human IPC-298 cell growth in a cell viability assay, IC50 = 3.55672 μM. SANGER
NCI-H1437 Growth Inhibition Assay Inhibition of human NCI-H1437 cell growth in a cell viability assay, IC50 = 3.55932 μM. SANGER
COR-L279 Growth Inhibition Assay Inhibition of human COR-L279 cell growth in a cell viability assay, IC50 = 3.56357 μM. SANGER
BT-20 Growth Inhibition Assay Inhibition of human BT-20 cell growth in a cell viability assay, IC50 = 3.6653 μM. SANGER
LK-2 Growth Inhibition Assay Inhibition of human LK-2 cell growth in a cell viability assay, IC50 = 3.71552 μM. SANGER
Saos-2 Growth Inhibition Assay Inhibition of human Saos-2 cell growth in a cell viability assay, IC50 = 3.7428 μM. SANGER
SKG-IIIa Growth Inhibition Assay Inhibition of human SKG-IIIa cell growth in a cell viability assay, IC50 = 3.76572 μM. SANGER
MC-CAR Growth Inhibition Assay Inhibition of human MC-CAR cell growth in a cell viability assay, IC50 = 3.78133 μM. SANGER
UACC-257 Growth Inhibition Assay Inhibition of human UACC-257 cell growth in a cell viability assay, IC50 = 3.81844 μM. SANGER
DU-4475 Growth Inhibition Assay Inhibition of human DU-4475 cell growth in a cell viability assay, IC50 = 3.87134 μM. SANGER
RERF-LC-MS Growth Inhibition Assay Inhibition of human RERF-LC-MS cell growth in a cell viability assay, IC50 = 3.98353 μM. SANGER
LB996-RCC Growth Inhibition Assay Inhibition of human LB996-RCC cell growth in a cell viability assay, IC50 = 3.98644 μM. SANGER
ES3 Growth Inhibition Assay Inhibition of human ES3 cell growth in a cell viability assay, IC50 = 4.05557 μM. SANGER
MMAC-SF Growth Inhibition Assay Inhibition of human MMAC-SF cell growth in a cell viability assay, IC50 = 4.05847 μM. SANGER
MEG-01 Growth Inhibition Assay Inhibition of human MEG-01 cell growth in a cell viability assay, IC50 = 4.06297 μM. SANGER
TE-1 Growth Inhibition Assay Inhibition of human TE-1 cell growth in a cell viability assay, IC50 = 4.09458 μM. SANGER
ES6 Growth Inhibition Assay Inhibition of human ES6 cell growth in a cell viability assay, IC50 = 4.10666 μM. SANGER
NCI-H1963 Growth Inhibition Assay Inhibition of human NCI-H1963 cell growth in a cell viability assay, IC50 = 4.11351 μM. SANGER
MZ7-mel Growth Inhibition Assay Inhibition of human MZ7-mel cell growth in a cell viability assay, IC50 = 4.15662 μM. SANGER
COLO-679 Growth Inhibition Assay Inhibition of human COLO-679 cell growth in a cell viability assay, IC50 = 4.16629 μM. SANGER
LB647-SCLC Growth Inhibition Assay Inhibition of human LB647-SCLC cell growth in a cell viability assay, IC50 = 4.22508 μM. SANGER
LoVo Growth Inhibition Assay Inhibition of human LoVo cell growth in a cell viability assay, IC50 = 4.22985 μM. SANGER
UACC-62 Growth Inhibition Assay Inhibition of human UACC-62 cell growth in a cell viability assay, IC50 = 4.25764 μM. SANGER
BE-13 Growth Inhibition Assay Inhibition of human BE-13 cell growth in a cell viability assay, IC50 = 4.36027 μM. SANGER
SW962 Growth Inhibition Assay Inhibition of human SW962 cell growth in a cell viability assay, IC50 = 4.36427 μM. SANGER
HEC-1 Growth Inhibition Assay Inhibition of human HEC-1 cell growth in a cell viability assay, IC50 = 4.39433 μM. SANGER
KOSC-2 Growth Inhibition Assay Inhibition of human KOSC-2 cell growth in a cell viability assay, IC50 = 4.39928 μM. SANGER
HSC-4 Growth Inhibition Assay Inhibition of human HSC-4 cell growth in a cell viability assay, IC50 = 4.40337 μM. SANGER
J82 Growth Inhibition Assay Inhibition of human J82 cell growth in a cell viability assay, IC50 = 4.43178 μM. SANGER
MLMA Growth Inhibition Assay Inhibition of human MLMA cell growth in a cell viability assay, IC50 = 4.4609 μM. SANGER
LU-165 Growth Inhibition Assay Inhibition of human LU-165 cell growth in a cell viability assay, IC50 = 4.46513 μM. SANGER
C8166 Growth Inhibition Assay Inhibition of human C8166 cell growth in a cell viability assay, IC50 = 4.48793 μM. SANGER
LC4-1 Growth Inhibition Assay Inhibition of human LC4-1 cell growth in a cell viability assay, IC50 = 4.51096 μM. SANGER
RT4 Growth Inhibition Assay Inhibition of human RT4 cell growth in a cell viability assay, IC50 = 4.61734 μM. SANGER
23132-87 Growth Inhibition Assay Inhibition of human 23132-87 cell growth in a cell viability assay, IC50 = 4.63837 μM. SANGER
COLO-320-HSR Growth Inhibition Assay Inhibition of human COLO-320-HSR cell growth in a cell viability assay, IC50 = 4.64656 μM. SANGER
KARPAS-45 Growth Inhibition Assay Inhibition of human KARPAS-45 cell growth in a cell viability assay, IC50 = 4.65165 μM. SANGER
LU-65 Growth Inhibition Assay Inhibition of human LU-65 cell growth in a cell viability assay, IC50 = 4.65198 μM. SANGER
PC-3 Growth Inhibition Assay Inhibition of human PC-3 cell growth in a cell viability assay, IC50 = 4.66509 μM. SANGER
IA-LM Growth Inhibition Assay Inhibition of human IA-LM cell growth in a cell viability assay, IC50 = 4.70635 μM. SANGER
SW684 Growth Inhibition Assay Inhibition of human SW684 cell growth in a cell viability assay, IC50 = 4.78838 μM. SANGER
MDA-MB-134-VI Growth Inhibition Assay Inhibition of human MDA-MB-134-VI cell growth in a cell viability assay, IC50 = 4.79107 μM. SANGER
KMOE-2 Growth Inhibition Assay Inhibition of human KMOE-2 cell growth in a cell viability assay, IC50 = 4.79789 μM. SANGER
PANC-08-13 Growth Inhibition Assay Inhibition of human PANC-08-13 cell growth in a cell viability assay, IC50 = 4.80463 μM. SANGER
NB12 Growth Inhibition Assay Inhibition of human NB12 cell growth in a cell viability assay, IC50 = 4.83764 μM. SANGER
CHP-126 Growth Inhibition Assay Inhibition of human CHP-126 cell growth in a cell viability assay, IC50 = 4.84468 μM. SANGER
HH Growth Inhibition Assay Inhibition of human HH cell growth in a cell viability assay, IC50 = 4.89303 μM. SANGER
A253 Growth Inhibition Assay Inhibition of human A253 cell growth in a cell viability assay, IC50 = 4.90307 μM. SANGER
MS-1 Growth Inhibition Assay Inhibition of human MS-1 cell growth in a cell viability assay, IC50 = 4.92448 μM. SANGER
OE33 Growth Inhibition Assay Inhibition of human OE33 cell growth in a cell viability assay, IC50 = 4.98609 μM. SANGER
LU-134-A Growth Inhibition Assay Inhibition of human LU-134-A cell growth in a cell viability assay, IC50 = 5.00007 μM. SANGER
NCI-H441 Growth Inhibition Assay Inhibition of human NCI-H441 cell growth in a cell viability assay, IC50 = 5.07203 μM. SANGER
Daudi Growth Inhibition Assay Inhibition of human Daudi cell growth in a cell viability assay, IC50 = 5.09119 μM. SANGER
EHEB Growth Inhibition Assay Inhibition of human EHEB cell growth in a cell viability assay, IC50 = 5.11224 μM. SANGER
SNU-C1 Growth Inhibition Assay Inhibition of human SNU-C1 cell growth in a cell viability assay, IC50 = 5.16875 μM. SANGER
TGBC24TKB Growth Inhibition Assay Inhibition of human TGBC24TKB cell growth in a cell viability assay, IC50 = 5.20055 μM. SANGER
T47D Growth Inhibition Assay Inhibition of human T47D cell growth in a cell viability assay, IC50 = 5.24803 μM. SANGER
NCI-N87 Growth Inhibition Assay Inhibition of human NCI-N87 cell growth in a cell viability assay, IC50 = 5.32699 μM. SANGER
MFE-280 Growth Inhibition Assay Inhibition of human MFE-280 cell growth in a cell viability assay, IC50 = 5.39569 μM. SANGER
KNS-81-FD Growth Inhibition Assay Inhibition of human KNS-81-FD cell growth in a cell viability assay, IC50 = 5.43617 μM. SANGER
BV-173 Growth Inhibition Assay Inhibition of human BV-173 cell growth in a cell viability assay, IC50 = 5.44899 μM. SANGER
L-363 Growth Inhibition Assay Inhibition of human L-363 cell growth in a cell viability assay, IC50 = 5.48279 μM. SANGER
SW1417 Growth Inhibition Assay Inhibition of human SW1417 cell growth in a cell viability assay, IC50 = 5.50405 μM. SANGER
OE19 Growth Inhibition Assay Inhibition of human OE19 cell growth in a cell viability assay, IC50 = 5.51721 μM. SANGER
AU565 Growth Inhibition Assay Inhibition of human AU565 cell growth in a cell viability assay, IC50 = 5.54849 μM. SANGER
EB-3 Growth Inhibition Assay Inhibition of human EB-3 cell growth in a cell viability assay, IC50 = 5.59768 μM. SANGER
LS-123 Growth Inhibition Assay Inhibition of human LS-123 cell growth in a cell viability assay, IC50 = 5.63714 μM. SANGER
Detroit562 Growth Inhibition Assay Inhibition of human Detroit562 cell growth in a cell viability assay, IC50 = 5.66765 μM. SANGER
MZ2-MEL Growth Inhibition Assay Inhibition of human MZ2-MEL cell growth in a cell viability assay, IC50 = 5.66902 μM. SANGER
SK-OV-3 Growth Inhibition Assay Inhibition of human SK-OV-3 cell growth in a cell viability assay, IC50 = 5.7181 μM. SANGER
BB49-HNC Growth Inhibition Assay Inhibition of human BB49-HNC cell growth in a cell viability assay, IC50 = 5.7794 μM. SANGER
L-428 Growth Inhibition Assay Inhibition of human L-428 cell growth in a cell viability assay, IC50 = 5.83896 μM. SANGER
D-502MG Growth Inhibition Assay Inhibition of human D-502MG cell growth in a cell viability assay, IC50 = 5.84231 μM. SANGER
IST-SL2 Growth Inhibition Assay Inhibition of human IST-SL2 cell growth in a cell viability assay, IC50 = 6.00753 μM. SANGER
MHH-PREB-1 Growth Inhibition Assay Inhibition of human MHH-PREB-1 cell growth in a cell viability assay, IC50 = 6.09945 μM. SANGER
LB2518-MEL Growth Inhibition Assay Inhibition of human LB2518-MEL cell growth in a cell viability assay, IC50 = 6.25712 μM. SANGER
MOLT-16 Growth Inhibition Assay Inhibition of human MOLT-16 cell growth in a cell viability assay, IC50 = 6.37751 μM. SANGER
EW-3 Growth Inhibition Assay Inhibition of human EW-3 cell growth in a cell viability assay, IC50 = 6.49826 μM. SANGER
SW13 Growth Inhibition Assay Inhibition of human SW13 cell growth in a cell viability assay, IC50 = 6.54451 μM. SANGER
MDA-MB-175-VII Growth Inhibition Assay Inhibition of human MDA-MB-175-VII cell growth in a cell viability assay, IC50 = 6.59915 μM. SANGER
NCI-H1651 Growth Inhibition Assay Inhibition of human NCI-H1651 cell growth in a cell viability assay, IC50 = 6.70771 μM. SANGER
TE-9 Growth Inhibition Assay Inhibition of human TE-9 cell growth in a cell viability assay, IC50 = 6.72501 μM. SANGER
MOLT-4 Growth Inhibition Assay Inhibition of human MOLT-4 cell growth in a cell viability assay, IC50 = 6.73673 μM. SANGER
SHP-77 Growth Inhibition Assay Inhibition of human SHP-77 cell growth in a cell viability assay, IC50 = 6.87231 μM. SANGER
HN Growth Inhibition Assay Inhibition of human HN cell growth in a cell viability assay, IC50 = 6.99041 μM. SANGER
NCI-H2196 Growth Inhibition Assay Inhibition of human NCI-H2196 cell growth in a cell viability assay, IC50 = 7.07134 μM. SANGER
HT-3 Growth Inhibition Assay Inhibition of human HT-3 cell growth in a cell viability assay, IC50 = 7.10261 μM. SANGER
SNU-475 Growth Inhibition Assay Inhibition of human SNU-475 cell growth in a cell viability assay, IC50 = 7.24992 μM. SANGER
LAMA-84 Growth Inhibition Assay Inhibition of human LAMA-84 cell growth in a cell viability assay, IC50 = 7.26693 μM. SANGER
BL-70 Growth Inhibition Assay Inhibition of human BL-70 cell growth in a cell viability assay, IC50 = 7.58685 μM. SANGER
HCC1187 Growth Inhibition Assay Inhibition of human HCC1187 cell growth in a cell viability assay, IC50 = 7.90746 μM. SANGER
CHL-1 Growth Inhibition Assay Inhibition of human CHL-1 cell growth in a cell viability assay, IC50 = 7.9551 μM. SANGER
LOXIMVI Growth Inhibition Assay Inhibition of human LOXIMVI cell growth in a cell viability assay, IC50 = 7.98834 μM. SANGER
NCI-H748 Growth Inhibition Assay Inhibition of human NCI-H748 cell growth in a cell viability assay, IC50 = 8.06778 μM. SANGER
LB771-HNC Growth Inhibition Assay Inhibition of human LB771-HNC cell growth in a cell viability assay, IC50 = 8.1383 μM. SANGER
JVM-2 Growth Inhibition Assay Inhibition of human JVM-2 cell growth in a cell viability assay, IC50 = 8.22065 μM. SANGER
SJSA-1 Growth Inhibition Assay Inhibition of human SJSA-1 cell growth in a cell viability assay, IC50 = 8.40363 μM. SANGER
SW1990 Growth Inhibition Assay Inhibition of human SW1990 cell growth in a cell viability assay, IC50 = 8.47225 μM. SANGER
NB5 Growth Inhibition Assay Inhibition of human NB5 cell growth in a cell viability assay, IC50 = 8.64343 μM. SANGER
ATN-1 Growth Inhibition Assay Inhibition of human ATN-1 cell growth in a cell viability assay, IC50 = 8.65295 μM. SANGER
HAL-01 Growth Inhibition Assay Inhibition of human HAL-01 cell growth in a cell viability assay, IC50 = 8.74413 μM. SANGER
LU-139 Growth Inhibition Assay Inhibition of human LU-139 cell growth in a cell viability assay, IC50 = 8.92615 μM. SANGER
no-10 Growth Inhibition Assay Inhibition of human no-10 cell growth in a cell viability assay, IC50 = 9.30633 μM. SANGER
NCI-H1694 Growth Inhibition Assay Inhibition of human NCI-H1694 cell growth in a cell viability assay, IC50 = 9.37253 μM. SANGER
COR-L88 Growth Inhibition Assay Inhibition of human COR-L88 cell growth in a cell viability assay, IC50 = 9.60055 μM. SANGER
22RV1 Growth Inhibition Assay Inhibition of human 22RV1 cell growth in a cell viability assay, IC50 = 9.72382 μM. SANGER
KM-H2 Growth Inhibition Assay Inhibition of human KM-H2 cell growth in a cell viability assay, IC50 = 9.7619 μM. SANGER
NCI-H1092 Growth Inhibition Assay Inhibition of human NCI-H1092 cell growth in a cell viability assay, IC50 = 9.79253 μM. SANGER
AsPC-1 Growth Inhibition Assay Inhibition of human AsPC-1 cell growth in a cell viability assay, IC50 = 9.85935 μM. SANGER
MHH-CALL-2 Growth Inhibition Assay Inhibition of human MHH-CALL-2 cell growth in a cell viability assay, IC50 = 10.0169 μM. SANGER
NCI-SNU-5 Growth Inhibition Assay Inhibition of human NCI-SNU-5 cell growth in a cell viability assay, IC50 = 10.3242 μM. SANGER
BPH-1 Growth Inhibition Assay Inhibition of human BPH-1 cell growth in a cell viability assay, IC50 = 10.3777 μM. SANGER
P12-ICHIKAWA Growth Inhibition Assay Inhibition of human P12-ICHIKAWA cell growth in a cell viability assay, IC50 = 11.1095 μM. SANGER
NCI-H727 Growth Inhibition Assay Inhibition of human NCI-H727 cell growth in a cell viability assay, IC50 = 11.1392 μM. SANGER
COR-L23 Growth Inhibition Assay Inhibition of human COR-L23 cell growth in a cell viability assay, IC50 = 11.1878 μM. SANGER
U-118-MG Growth Inhibition Assay Inhibition of human U-118-MG cell growth in a cell viability assay, IC50 = 11.2779 μM. SANGER
GAK Growth Inhibition Assay Inhibition of human GAK cell growth in a cell viability assay, IC50 = 11.3348 μM. SANGER
HCC2998 Growth Inhibition Assay Inhibition of human HCC2998 cell growth in a cell viability assay, IC50 = 11.4251 μM. SANGER
COLO-829 Growth Inhibition Assay Inhibition of human COLO-829 cell growth in a cell viability assay, IC50 = 11.6192 μM. SANGER
CAL-33 Growth Inhibition Assay Inhibition of human CAL-33 cell growth in a cell viability assay, IC50 = 11.9946 μM. SANGER
EB2 Growth Inhibition Assay Inhibition of human EB2 cell growth in a cell viability assay, IC50 = 11.9968 μM. SANGER
THP-1 Growth Inhibition Assay Inhibition of human THP-1 cell growth in a cell viability assay, IC50 = 12.0748 μM. SANGER
ES1 Growth Inhibition Assay Inhibition of human ES1 cell growth in a cell viability assay, IC50 = 12.0862 μM. SANGER
647-V Growth Inhibition Assay Inhibition of human 647-V cell growth in a cell viability assay, IC50 = 12.0972 μM. SANGER
NCI-H520 Growth Inhibition Assay Inhibition of human NCI-H520 cell growth in a cell viability assay, IC50 = 12.2896 μM. SANGER
JEG-3 Growth Inhibition Assay Inhibition of human JEG-3 cell growth in a cell viability assay, IC50 = 12.5281 μM. SANGER
A388 Growth Inhibition Assay Inhibition of human A388 cell growth in a cell viability assay, IC50 = 12.6997 μM. SANGER
Mewo Growth Inhibition Assay Inhibition of human Mewo cell growth in a cell viability assay, IC50 = 12.8578 μM. SANGER
KNS-42 Growth Inhibition Assay Inhibition of human KNS-42 cell growth in a cell viability assay, IC50 = 12.9918 μM. SANGER
MDA-MB-468 Growth Inhibition Assay Inhibition of human MDA-MB-468 cell growth in a cell viability assay, IC50 = 13.0366 μM. SANGER
SiHa Growth Inhibition Assay Inhibition of human SiHa cell growth in a cell viability assay, IC50 = 13.1045 μM. SANGER
C2BBe1 Growth Inhibition Assay Inhibition of human C2BBe1 cell growth in a cell viability assay, IC50 = 13.715 μM. SANGER
HDLM-2 Growth Inhibition Assay Inhibition of human HDLM-2 cell growth in a cell viability assay, IC50 = 13.7375 μM. SANGER
PFSK-1 Growth Inhibition Assay Inhibition of human PFSK-1 cell growth in a cell viability assay, IC50 = 14.1067 μM. SANGER
NCI-H446 Growth Inhibition Assay Inhibition of human NCI-H446 cell growth in a cell viability assay, IC50 = 14.3535 μM. SANGER
EKVX Growth Inhibition Assay Inhibition of human EKVX cell growth in a cell viability assay, IC50 = 14.5135 μM. SANGER
DJM-1 Growth Inhibition Assay Inhibition of human DJM-1 cell growth in a cell viability assay, IC50 = 14.5549 μM. SANGER
K-562 Growth Inhibition Assay Inhibition of human K-562 cell growth in a cell viability assay, IC50 = 14.5747 μM. SANGER
CP50-MEL-B Growth Inhibition Assay Inhibition of human CP50-MEL-B cell growth in a cell viability assay, IC50 = 14.6287 μM. SANGER
SK-NEP-1 Growth Inhibition Assay Inhibition of human SK-NEP-1 cell growth in a cell viability assay, IC50 = 15.2382 μM. SANGER
Ca9-22 Growth Inhibition Assay Inhibition of human Ca9-22 cell growth in a cell viability assay, IC50 = 15.3006 μM. SANGER
M14 Growth Inhibition Assay Inhibition of human M14 cell growth in a cell viability assay, IC50 = 15.8452 μM. SANGER
Calu-6 Growth Inhibition Assay Inhibition of human Calu-6 cell growth in a cell viability assay, IC50 = 15.9582 μM. SANGER
NCI-H1838 Growth Inhibition Assay Inhibition of human NCI-H1838 cell growth in a cell viability assay, IC50 = 15.9636 μM. SANGER
T84 Growth Inhibition Assay Inhibition of human T84 cell growth in a cell viability assay, IC50 = 16.4497 μM. SANGER
ME-180 Growth Inhibition Assay Inhibition of human ME-180 cell growth in a cell viability assay, IC50 = 17.4632 μM. SANGER
LP-1 Growth Inhibition Assay Inhibition of human LP-1 cell growth in a cell viability assay, IC50 = 17.5062 μM. SANGER
DMS-153 Growth Inhibition Assay Inhibition of human DMS-153 cell growth in a cell viability assay, IC50 = 18.0166 μM. SANGER
SW1463 Growth Inhibition Assay Inhibition of human SW1463 cell growth in a cell viability assay, IC50 = 18.1741 μM. SANGER
J-RT3-T3-5 Growth Inhibition Assay Inhibition of human J-RT3-T3-5 cell growth in a cell viability assay, IC50 = 18.2392 μM. SANGER
Ca-Ski Growth Inhibition Assay Inhibition of human Ca-Ski cell growth in a cell viability assay, IC50 = 18.5343 μM. SANGER
CAL-148 Growth Inhibition Assay Inhibition of human CAL-148 cell growth in a cell viability assay, IC50 = 18.543 μM. SANGER
NB10 Growth Inhibition Assay Inhibition of human NB10 cell growth in a cell viability assay, IC50 = 18.6146 μM. SANGER
HPAF-II Growth Inhibition Assay Inhibition of human HPAF-II cell growth in a cell viability assay, IC50 = 19.4871 μM. SANGER
CAL-72 Growth Inhibition Assay Inhibition of human CAL-72 cell growth in a cell viability assay, IC50 = 20.1775 μM. SANGER
TT Growth Inhibition Assay Inhibition of human TT cell growth in a cell viability assay, IC50 = 20.2415 μM. SANGER
RPMI-8226 Growth Inhibition Assay Inhibition of human RPMI-8226 cell growth in a cell viability assay, IC50 = 20.3787 μM. SANGER
D-283MED Growth Inhibition Assay Inhibition of human D-283MED cell growth in a cell viability assay, IC50 = 20.7314 μM. SANGER
MIA-PaCa-2 Growth Inhibition Assay Inhibition of human MIA-PaCa-2 cell growth in a cell viability assay, IC50 = 20.74 μM. SANGER
CAMA-1 Growth Inhibition Assay Inhibition of human CAMA-1 cell growth in a cell viability assay, IC50 = 21.2958 μM. SANGER
EW-24 Growth Inhibition Assay Inhibition of human EW-24 cell growth in a cell viability assay, IC50 = 21.296 μM. SANGER
NCI-H2227 Growth Inhibition Assay Inhibition of human NCI-H2227 cell growth in a cell viability assay, IC50 = 21.3845 μM. SANGER
SW948 Growth Inhibition Assay Inhibition of human SW948 cell growth in a cell viability assay, IC50 = 21.4582 μM. SANGER
C32 Growth Inhibition Assay Inhibition of human C32 cell growth in a cell viability assay, IC50 = 21.8635 μM. SANGER
HL-60 Growth Inhibition Assay Inhibition of human HL-60 cell growth in a cell viability assay, IC50 = 22.5901 μM. SANGER
SK-MEL-1 Growth Inhibition Assay Inhibition of human SK-MEL-1 cell growth in a cell viability assay, IC50 = 22.6933 μM. SANGER
D-542MG Growth Inhibition Assay Inhibition of human D-542MG cell growth in a cell viability assay, IC50 = 23.1396 μM. SANGER
NCI-H2081 Growth Inhibition Assay Inhibition of human NCI-H2081 cell growth in a cell viability assay, IC50 = 23.4308 μM. SANGER
NOMO-1 Growth Inhibition Assay Inhibition of human NOMO-1 cell growth in a cell viability assay, IC50 = 23.5328 μM. SANGER
S-117 Growth Inhibition Assay Inhibition of human S-117 cell growth in a cell viability assay, IC50 = 24.1114 μM. SANGER
KP-N-YS Growth Inhibition Assay Inhibition of human KP-N-YS cell growth in a cell viability assay, IC50 = 24.6488 μM. SANGER
HCC1937 Growth Inhibition Assay Inhibition of human HCC1937 cell growth in a cell viability assay, IC50 = 24.6509 μM. SANGER
RVH-421 Growth Inhibition Assay Inhibition of human RVH-421 cell growth in a cell viability assay, IC50 = 24.8948 μM. SANGER
FTC-133 Growth Inhibition Assay Inhibition of human FTC-133 cell growth in a cell viability assay, IC50 = 25.6658 μM. SANGER
NCI-H1395 Growth Inhibition Assay Inhibition of human NCI-H1395 cell growth in a cell viability assay, IC50 = 25.9419 μM. SANGER
KU-19-19 Growth Inhibition Assay Inhibition of human KU-19-19 cell growth in a cell viability assay, IC50 = 26.103 μM. SANGER
NCI-H1623 Growth Inhibition Assay Inhibition of human NCI-H1623 cell growth in a cell viability assay, IC50 = 26.1282 μM. SANGER
LB373-MEL-D Growth Inhibition Assay Inhibition of human LB373-MEL-D cell growth in a cell viability assay, IC50 = 26.4395 μM. SANGER
NCI-H1882 Growth Inhibition Assay Inhibition of human NCI-H1882 cell growth in a cell viability assay, IC50 = 26.4574 μM. SANGER
HT Growth Inhibition Assay Inhibition of human HT cell growth in a cell viability assay, IC50 = 27.1395 μM. SANGER
SF539 Growth Inhibition Assay Inhibition of human SF539 cell growth in a cell viability assay, IC50 = 27.9248 μM. SANGER
NCI-H2171 Growth Inhibition Assay Inhibition of human NCI-H2171 cell growth in a cell viability assay, IC50 = 28.6587 μM. SANGER
MDA-MB-415 Growth Inhibition Assay Inhibition of human MDA-MB-415 cell growth in a cell viability assay, IC50 = 29.1701 μM. SANGER
SW756 Growth Inhibition Assay Inhibition of human SW756 cell growth in a cell viability assay, IC50 = 29.2866 μM. SANGER
MDA-MB-361 Growth Inhibition Assay Inhibition of human MDA-MB-361 cell growth in a cell viability assay, IC50 = 29.5408 μM. SANGER
NCI-H1581 Growth Inhibition Assay Inhibition of human NCI-H1581 cell growth in a cell viability assay, IC50 = 29.8489 μM. SANGER
OMC-1 Growth Inhibition Assay Inhibition of human OMC-1 cell growth in a cell viability assay, IC50 = 30.0647 μM. SANGER
HT-1197 Growth Inhibition Assay Inhibition of human HT-1197 cell growth in a cell viability assay, IC50 = 30.4937 μM. SANGER
TE-5 Growth Inhibition Assay Inhibition of human TE-5 cell growth in a cell viability assay, IC50 = 31.3348 μM. SANGER
HCC1419 Growth Inhibition Assay Inhibition of human HCC1419 cell growth in a cell viability assay, IC50 = 31.5056 μM. SANGER
KE-37 Growth Inhibition Assay Inhibition of human KE-37 cell growth in a cell viability assay, IC50 = 31.9635 μM. SANGER
DMS-53 Growth Inhibition Assay Inhibition of human DMS-53 cell growth in a cell viability assay, IC50 = 32.1035 μM. SANGER
EW-11 Growth Inhibition Assay Inhibition of human EW-11 cell growth in a cell viability assay, IC50 = 32.9248 μM. SANGER
MDA-MB-453 Growth Inhibition Assay Inhibition of human MDA-MB-453 cell growth in a cell viability assay, IC50 = 34.2262 μM. SANGER
SK-MEL-28 Growth Inhibition Assay Inhibition of human SK-MEL-28 cell growth in a cell viability assay, IC50 = 34.81 μM. SANGER
HuP-T4 Growth Inhibition Assay Inhibition of human HuP-T4 cell growth in a cell viability assay, IC50 = 34.9442 μM. SANGER
LNCaP-Clone-FGC Growth Inhibition Assay Inhibition of human LNCaP-Clone-FGC cell growth in a cell viability assay, IC50 = 35.3355 μM. SANGER
SK-N-AS Growth Inhibition Assay Inhibition of human SK-N-AS cell growth in a cell viability assay, IC50 = 35.3997 μM. SANGER
NCI-H1417 Growth Inhibition Assay Inhibition of human NCI-H1417 cell growth in a cell viability assay, IC50 = 35.644 μM. SANGER
SK-N-DZ Growth Inhibition Assay Inhibition of human SK-N-DZ cell growth in a cell viability assay, IC50 = 36.2005 μM. SANGER
MKN7 Growth Inhibition Assay Inhibition of human MKN7 cell growth in a cell viability assay, IC50 = 36.2826 μM. SANGER
YAPC Growth Inhibition Assay Inhibition of human YAPC cell growth in a cell viability assay, IC50 = 37.0099 μM. SANGER
HCC1954 Growth Inhibition Assay Inhibition of human HCC1954 cell growth in a cell viability assay, IC50 = 37.4063 μM. SANGER
NCI-H209 Growth Inhibition Assay Inhibition of human NCI-H209 cell growth in a cell viability assay, IC50 = 37.8896 μM. SANGER
NCI-H2141 Growth Inhibition Assay Inhibition of human NCI-H2141 cell growth in a cell viability assay, IC50 = 38.0329 μM. SANGER
LS-513 Growth Inhibition Assay Inhibition of human LS-513 cell growth in a cell viability assay, IC50 = 38.3118 μM. SANGER
DOHH-2 Growth Inhibition Assay Inhibition of human DOHH-2 cell growth in a cell viability assay, IC50 = 38.9351 μM. SANGER
NCI-H596 Growth Inhibition Assay Inhibition of human NCI-H596 cell growth in a cell viability assay, IC50 = 39.1801 μM. SANGER
TYK-nu Growth Inhibition Assay Inhibition of human TYK-nu cell growth in a cell viability assay, IC50 = 40.3953 μM. SANGER
CP66-MEL Growth Inhibition Assay Inhibition of human CP66-MEL cell growth in a cell viability assay, IC50 = 40.603 μM. SANGER
SK-MEL-24 Growth Inhibition Assay Inhibition of human SK-MEL-24 cell growth in a cell viability assay, IC50 = 41.4873 μM. SANGER
Caov-3 Growth Inhibition Assay Inhibition of human Caov-3 cell growth in a cell viability assay, IC50 = 41.5317 μM. SANGER
HCC1143 Growth Inhibition Assay Inhibition of human HCC1143 cell growth in a cell viability assay, IC50 = 41.6764 μM. SANGER
EVSA-T Growth Inhibition Assay Inhibition of human EVSA-T cell growth in a cell viability assay, IC50 = 42.8954 μM. SANGER
PLC-PRF-5 Growth Inhibition Assay Inhibition of human PLC-PRF-5 cell growth in a cell viability assay, IC50 = 44.411 μM. SANGER
NCI-H187 Growth Inhibition Assay Inhibition of human NCI-H187 cell growth in a cell viability assay, IC50 = 44.9084 μM. SANGER
EC-GI-10 Growth Inhibition Assay Inhibition of human EC-GI-10 cell growth in a cell viability assay, IC50 = 46.7464 μM. SANGER
UACC-893 Growth Inhibition Assay Inhibition of human UACC-893 cell growth in a cell viability assay, IC50 = 47.3736 μM. SANGER
Click to View More Cell Line Experimental Data

Biological Activity

Description Midostaurin is a multi-targeted kinase inhibitor, including PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50 ranging from 80-500 nM.
Targets
PKCα [1]
(Cell-free assay)
PKCγ [1]
(Cell-free assay)
PKCβ1 [1]
(Cell-free assay)
PKCβ2 [1]
(Cell-free assay)
PPK [1]
(Cell-free assay)
Click to View More Targets
22 nM 24 nM 30 nM 31 nM 38 nM
In vitro
In vitro Midostaurin(pkc412) is a broad spectrum protein kinase inhibitor. Midostaurin(pkc412) interacts strongly with ATP binding sites of the conventional PKC-α, -β and -γ, PDGFRβ, VEGF-R2, VEGF-R1 and the cyclin-dependant kinase 1-cyclin B complex. Midostaurin(pkc412) inhibits the growth of various human and animal cell lines in vitro at similar submicromolar concentrations. Midostaurin(pkc412) also effectively inhibits the in vitro proliferation of glioblastoma and induced the accumulation of cells in G2/M and formation of giant nuclei with extensive fragmentation and apoptotic bodies. Midostaurin(pkc412) is able to reverse the p-glycoprotein-mediated multidrug resistance of tumor cells in vitro. [1]
Cell Research Cell lines A549, NCI-H520
Concentrations ~1.0 μM
Incubation Time 24-72 h
Method Each well is added with 5 mM WST-1 and 0.2 mM 1-methoxy PMS and the absorbance at 450 nm is measured by a Microplate Reader.
Experimental Result Images Methods Biomarkers Images PMID
Western blot p-TYR / p-STAT5 / STAT5 / p-S6 / S6 / p-MAPK / MAPK / p-AKT / AKT PKCα / PKCβ1 / PKCβ2 / PKCγ / PKCη / p-PKC / p-Bad / Bad / p-Bcl2 / Bcl-2 / p-p65 / p65 28881711
In Vivo
In vivo Midostaurin(pkc412) may suppress tumor growth by inhibiting tumor angiogenesis (via its effects on the VEGF receptor tyrosine kinases) in addition to directly inhibiting tumor cell proliferation (via its effects on PKCs). This anti-angiogenic action may contribute to the antimetastatic and broad antitumor activity displayed by midostaurin(pkc412), as well as the synergy with cytotoxic agents, including doxorubicin, cyclophosphamide, cisplatin and gemcitabine. When given orally, the maximally tolerated dose for midostaurin(pkc412) is >300 mg/kg. [1]
Animal Research Animal Models Colo 205 colorectal tumors xenograft
Dosages 50 mg/kg, 200 mg/kg, once daily
Administration p.o.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05488613 Completed
Acute Myeloid Leukemia (AML)
Novartis Pharmaceuticals|Novartis
September 24 2020 --
NCT03951961 Terminated
Acute Myeloid Leukemia Adult
University of Jena|Ludwig-Maximilians - University of Munich
March 20 2020 Phase 2
NCT04097470 Active not recruiting
AML/MDS
Stichting Hemato-Oncologie voor Volwassenen Nederland|Swiss Group for Clinical Cancer Research
December 5 2019 Phase 2

Chemical Information & Solubility

Molecular Weight 570.64 Formula

C35H30N4O4

CAS No. 120685-11-2 SDF Download Midostaurin SDF
Smiles CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( (175.24 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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