Ibutilide Fumarate

Licensed by Pfizer Catalog No.S2118 Synonyms: U-70226E

Ibutilide Fumarate Chemical Structure

Molecular Weight(MW): 885.23

Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.

Size Price Stock Quantity  
In DMSO USD 140 In stock
USD 67 In stock
USD 467 In stock
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Description Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.
Targets
Sodium channel [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 89 mg/mL (100.53 mM)
Water 89 mg/mL (100.53 mM)
Ethanol 89 mg/mL (100.53 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 885.23
Formula

(C20H36N2O3S)2.C4H4O<䲧甙Ỵ甚㧀甘膉璃瓮跠ৱᐨ'ৱĀ

CAS No. 122647-32-9
Storage powder
in solvent
Synonyms U-70226E

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03834883 Not yet recruiting Long QT Syndrome|Abnormalities Drug-Induced Indiana University|American Heart Association|Purdue University April 1 2019 Phase 4
NCT03834883 Not yet recruiting Long QT Syndrome|Abnormalities Drug-Induced Indiana University|American Heart Association|Purdue University April 1 2019 Phase 4
NCT03370536 Terminated Atrial Fibrillation|Persistent Atrial Fibrillation Vivek Reddy|Medtronic|Icahn School of Medicine at Mount Sinai November 1 2017 Not Applicable
NCT03370536 Terminated Atrial Fibrillation|Persistent Atrial Fibrillation Vivek Reddy|Medtronic|Icahn School of Medicine at Mount Sinai November 1 2017 Not Applicable
NCT02513940 Completed Long QT Syndrome Indiana University|American Heart Association|Purdue University May 2016 Phase 4
NCT02513940 Completed Long QT Syndrome Indiana University|American Heart Association|Purdue University May 2016 Phase 4

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID