Ibutilide Fumarate

Catalog No.S2118 Batch:S211851

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Technical Data

Formula

(C20H36N2O3S)2.C4H4O4

Molecular Weight 885.23 CAS No. 122647-32-9
Solubility (25°C)* In vitro DMSO 89 mg/mL (100.53 mM)
Water 89 mg/mL (100.53 mM)
Ethanol 89 mg/mL (100.53 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description Ibutilide Fumarate (U-70226E,Corvert Fumarate) is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm by induction of slow inward sodium current, which prolongs action potential and refractory period of myocardial cells.
Targets
Sodium channel [1]

Protocol (from reference)

Selleck's Ibutilide Fumarate has been cited by 2 publications

A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KV11.1 (hERG) Variants [ Mol Pharmacol, 2022, 101(4):236-245] PubMed: 35125346
Evaluating class III antiarrhythmic agents as novel MYC targeting drugs in ovarian cancer [Belur Nagaraj A Gynecol Oncol, 2018, 151(3):525-532] PubMed: 30301560

RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.