GSK3117391

Catalog No.S1313 Synonyms: GSK3117391A, HDAC-IN-3

For research use only.

GSK3117391 (GSK3117391A, HDAC-IN-3) is a potent histone deacetylase (HDAC) inhibitor.

GSK3117391 Chemical Structure

CAS No. 1018673-42-1

Purity & Quality Control

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Biological Activity

Description GSK3117391 (GSK3117391A, HDAC-IN-3) is a potent histone deacetylase (HDAC) inhibitor.
Targets
HDAC [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 403.52
Formula

C22H33N3O4

CAS No. 1018673-42-1
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02965599 Terminated Drug: GSK3117391|Drug: Placebo Arthritis Rheumatoid GlaxoSmithKline December 27 2016 Phase 2

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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