Esomeprazole sodium

For research use only.

Catalog No.S2233

2 publications

Esomeprazole sodium Chemical Structure

CAS No. 161796-78-7

Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

Size Price Stock Quantity  
10mM (1mL in DMSO) EUR 245 In stock
EUR 167 In stock
EUR 314 In stock
EUR 953 In stock
EUR 2427 In stock
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Biological Activity

Description Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.
Targets
ATPase [1]

Protocol

Solubility (25°C)

In vitro DMSO 73 mg/mL (198.69 mM)
Water 73 mg/mL (198.69 mM)
Ethanol 73 mg/mL (198.69 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 367.4
Formula

C17H18N3O3S.Na

CAS No. 161796-78-7
Storage powder
in solvent
Synonyms N/A
Smiles CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=C(C=C3)OC.[Na+]

In vivo Formulation Calculator (Clear solution)

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04494243 Not yet recruiting Drug: AD-214 10/600mg|Drug: Rabeprazole 10mg Gastroesophageal Reflux Disease Addpharma Inc. August 10 2020 Phase 1
NCT04156646 Completed Drug: Balovaptan|Drug: Esomeprazole Autism Spectrum Disorder Hoffmann-La Roche November 19 2019 Phase 1
NCT03708211 Completed Drug: TAK-931 PIC|Drug: TAK-931 Tablet|Drug: Esomeprazole Neoplasms Advanced Solid Millennium Pharmaceuticals Inc.|Takeda March 28 2019 Phase 1
NCT03372850 Unknown status Drug: HIP1601|Drug: HGP1705 Healthy Hanmi Pharmaceutical Company Limited February 15 2018 Phase 1
NCT03083639 Completed Drug: Esomeprazole Capsule|Drug: Esomeprazole Tablet Healthy Participants Takeda March 27 2017 Phase 1

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