Esomeprazole sodium

Catalog No.S2233

Esomeprazole sodium Chemical Structure

Molecular Weight(MW): 367.4

Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

Size Price Stock Quantity  
In DMSO USD 250 In stock
USD 170 In stock
USD 320 In stock
USD 970 In stock
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Biological Activity

Description Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.
Targets
ATPase [1]

Protocol

Solubility (25°C)

In vitro DMSO 73 mg/mL (198.69 mM)
Water 73 mg/mL (198.69 mM)
Ethanol 73 mg/mL (198.69 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 367.4
Formula

C17H18N3O3S.Na

CAS No. 161796-78-7
Storage powder
in solvent
Synonyms N/A

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03708211 Recruiting Drug: TAK-931 PIC|Drug: TAK-931 Tablet|Drug: Esomeprazole Neoplasms Advanced Solid Millennium Pharmaceuticals Inc.|Takeda March 28 2019 Phase 1
NCT03372850 Not yet recruiting Drug: HIP1601|Drug: HGP1705 Healthy Hanmi Pharmaceutical Company Limited February 15 2018 Phase 1
NCT03083639 Completed Drug: Esomeprazole Capsule|Drug: Esomeprazole Tablet Healthy Participants Takeda March 27 2017 Phase 1
NCT03092193 Unknown status Drug: Naproxen|Drug: Naproxen-esomeprazole Poor Metabolizer Due to Cytochrome P450 CYP2C9 Variant|Poor Metabolizer Due to Cytochrome p450 CYP2C19 Variant University of Sao Paulo|Fundação de Amparo à Pesquisa do Estado de São Paulo March 1 2017 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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ATPase Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID