Cyproheptadine hydrochloride sesquihydrate

Synonyms: Periactin hydrochloride, Peritol

Cyproheptadine hydrochloride (Periactin, Peritol) is non-selective 5HT2 antagonist with IC50 of 0.6 nM. Also a SETD7/9 inhibitor.

Cyproheptadine hydrochloride sesquihydrate Chemical Structure

Cyproheptadine hydrochloride sesquihydrate Chemical Structure

CAS: 41354-29-4

Selleck's Cyproheptadine hydrochloride sesquihydrate has been cited by 1 publication

Purity & Quality Control

Batch: S463501 DMSO] 70 mg/mL] false] Ethanol] 13 mg/mL] false] Water] Insoluble] false Purity: 99.86%
99.86

Cyproheptadine hydrochloride sesquihydrate Related Products

Choose Selective 5-HT Receptor Inhibitors

Biological Activity

Description Cyproheptadine hydrochloride (Periactin, Peritol) is non-selective 5HT2 antagonist with IC50 of 0.6 nM. Also a SETD7/9 inhibitor.
Targets
5-HT2 [1] SETD7/9 [3]
0.6 nM 1 μM

Chemical Information & Solubility

Molecular Weight 350.88 Formula

C21H21N.HCl.3/2H2O

CAS No. 41354-29-4 SDF Download Cyproheptadine hydrochloride sesquihydrate SDF
Smiles CN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1.CN1CCC(=C2C3=CC=CC=C3C=CC4=CC=CC=C42)CC1.O.O.O.Cl.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 70 mg/mL ( (199.49 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 13 mg/mL

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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