CK1-IN-1

Catalog No.S0350 Synonyms: PUN51207, Compound 1C

For research use only.

CK1-IN-1 (PUN51207, Compound 1C) is an inhibitor of casein kinase 1 (CK1) with IC50 of 15 nM, 16 nM and 73 nM for CK1δ, CK1ε and p38α MAPK, respectively.

CK1-IN-1 Chemical Structure

CAS No. 1784751-20-7

Purity & Quality Control

Choose Selective Casein Kinase Inhibitors

Biological Activity

Description CK1-IN-1 (PUN51207, Compound 1C) is an inhibitor of casein kinase 1 (CK1) with IC50 of 15 nM, 16 nM and 73 nM for CK1δ, CK1ε and p38α MAPK, respectively.
Targets
CK1δ [1]
(Cell-free assay)
CK1ε [1]
(Cell-free assay)
p38αMAPK [1]
(Cell-free assay)
15 nM 16 nM 73 nM

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 383.39
Formula

C24H15F2N3

CAS No. 1784751-20-7
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC=C2C(=C1)C=CC(=C2F)C3=NC(=C(N3)C4=CC=NC=C4)C5=CC=C(C=C5)F

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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