cis-Resveratrol

For research use only.

Catalog No.S3168 Synonyms: cis-RESV, cRes, (Z)-Resveratrol

cis-Resveratrol Chemical Structure

CAS No. 61434-67-1

cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) is the Cis isomer of Resveratrol. Resveratrol is a natural phenolic compound with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol is an inhibitor of pregnane X receptor (PXR) and an activator of Nrf2 and SIRT1 and may induce apoptosis. Resveratrol also inhibits a wide spectrum of targets including 5-lipoxygenase (LOX), cyclooxygenase (COX), IKKβ, DNA polymerases α and δ with IC50 of 2.7 μM, <1 μM, 1 μM, 3.3 μM and 5 μM, respectively.

Purity & Quality Control

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Biological Activity

Description cis-Resveratrol (cis-RESV, cRes, (Z)-Resveratrol) is the Cis isomer of Resveratrol. Resveratrol is a natural phenolic compound with anti-oxidant, anti-inflammatory, cardioprotective, and anti-cancer properties. Resveratrol is an inhibitor of pregnane X receptor (PXR) and an activator of Nrf2 and SIRT1 and may induce apoptosis. Resveratrol also inhibits a wide spectrum of targets including 5-lipoxygenase (LOX), cyclooxygenase (COX), IKKβ, DNA polymerases α and δ with IC50 of 2.7 μM, <1 μM, 1 μM, 3.3 μM and 5 μM, respectively.
Targets
PXR [1]
()
Nrf2 [2]
()
SIRT1 [2]
()
COX [3]
(Cell-free assay)
IKKβ [3]
(Cell-free assay)
1 μM 1 μM

Protocol

Solubility (25°C)

In vitro DMSO 46 mg/mL (201.54 mM)
Water Insoluble
Ethanol '''46 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 228.24
Formula

C14H12O3

CAS No. 61434-67-1
Storage powder
in solvent
Synonyms cis-RESV, cRes, (Z)-Resveratrol

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04886635 Recruiting Other: Active surveillance Cancer of Esophagus Bas P. L. Wijnhoven|Erasmus Medical Center March 9 2021 --
NCT04206943 Unknown status Biological: Car-T Cell Therapy Acute Lymphoblastic Leukemia|Non Hodgkin Lymphoma Acibadem University|Acıbadem Atunizade Hospital|The Scientific and Technological Research Council of Turkey|Acıbadem Labcell October 12 2019 Phase 1|Phase 2
NCT03994913 Recruiting Biological: CAR-CD19 T Cells Refractory B-Cell Non-Hodgkin Lymphoma|Relapsed B-cell Non-Hodgkin Lymphoma Carsgen Therapeutics Ltd.|First Affiliated Hospital of Zhejiang University|RenJi Hospital August 14 2019 Phase 1|Phase 2
NCT04117516 Active not recruiting Procedure: Open surgery|Procedure: Percutaneous surgery Carpal Tunnel Syndrome Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana June 5 2019 Not Applicable
NCT03248063 Recruiting Drug: Cloxacillin|Drug: Cefazolin Bacteremia Due to Methicillin Susceptible Staphylococcus Aureus Assistance Publique - Hôpitaux de Paris September 5 2018 Not Applicable

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID