Cevimeline HCl hemihydrate

Synonyms: AF 102B, SNI 2011, SNK 508

Cevimeline HCl hemihydrate(AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.

Cevimeline HCl hemihydrate Chemical Structure

Cevimeline HCl hemihydrate Chemical Structure

CAS No. 153504-70-2

Purity & Quality Control

Batch: S643201 DMSO]40 mg/mL]false]Water]40 mg/mL]false]Ethanol]40 mg/mL]false Purity: 98.06%
98.06

Cevimeline HCl hemihydrate Related Products

Signaling Pathway

Biological Activity

Description Cevimeline HCl hemihydrate(AF 102B, SNI 2011, SNK 508) is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00466388 Completed
Xerostomia
American Academy of Otolaryngology-Head and Neck Surgery Foundation|Duke University
May 2007 Phase 4

Chemical Information & Solubility

Molecular Weight 244.78 Formula

C10H18ClNOS.1/2H2O

CAS No. 153504-70-2 SDF --
Smiles CC1OC2(CN3CCC2CC3)CS1.CC1OC2(CN3CCC2CC3)CS1.O.Cl.Cl
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 40 mg/mL ( (163.41 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 40 mg/mL

Ethanol : 40 mg/mL


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Cevimeline HCl hemihydrate | Cevimeline HCl hemihydrate ic50 | Cevimeline HCl hemihydrate price | Cevimeline HCl hemihydrate cost | Cevimeline HCl hemihydrate solubility dmso | Cevimeline HCl hemihydrate purchase | Cevimeline HCl hemihydrate manufacturer | Cevimeline HCl hemihydrate research buy | Cevimeline HCl hemihydrate order | Cevimeline HCl hemihydrate mouse | Cevimeline HCl hemihydrate chemical structure | Cevimeline HCl hemihydrate mw | Cevimeline HCl hemihydrate molecular weight | Cevimeline HCl hemihydrate datasheet | Cevimeline HCl hemihydrate supplier | Cevimeline HCl hemihydrate in vitro | Cevimeline HCl hemihydrate cell line | Cevimeline HCl hemihydrate concentration | Cevimeline HCl hemihydrate nmr