Home Microbiology Bacterial inhibitor Cefepime For research use only.

Cefepime

Synonyms: BMY-28142

Cefepime (BMY-28142) is a fourth-generation cephalosporin used to treat a wide range of Gram-positive and Gram-negative bacterial infections. It is approved for the management of pneumonia, urinary tract infections, skin and soft-tissue infections, intra-abdominal infections, and febrile neutropenia. Cefepime exerts its bactericidal effect by covalently binding and inhibiting penicillin-binding proteins (PBPs), thereby disrupting the final step of bacterial cell wall synthesis and leading to cell death.

Cefepime Chemical Structure

Cefepime Chemical Structure

CAS No. 88040-23-7

Purity & Quality Control

Batch: E708901 DMSO]96 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.74%
99.74

Cefepime Related Products

Biological Activity

Description Cefepime (BMY-28142) is a fourth-generation cephalosporin used to treat a wide range of Gram-positive and Gram-negative bacterial infections. It is approved for the management of pneumonia, urinary tract infections, skin and soft-tissue infections, intra-abdominal infections, and febrile neutropenia. Cefepime exerts its bactericidal effect by covalently binding and inhibiting penicillin-binding proteins (PBPs), thereby disrupting the final step of bacterial cell wall synthesis and leading to cell death.

Chemical Information & Solubility

Molecular Weight 480.56 Formula

C19H24N6O5S2
CAS No. 88040-23-7 SDF Download Cefepime SDF
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 96 mg/mL ( (199.76 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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