CAS No. 88040-23-7
Batch:
Purity:99.74
Chemical Structure
Check the
Cefepime
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(1-methylpyrrolidin-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate | |
|---|---|---|
| CAS Number | 88040-23-7 | |
| Molecular Formula |
C19H24N6O5S2 |
|
| Molecular Weight (MW) | 480.56 | |
| InChIKey | HVFLCNVBZFFHBT-ZKDACBOMSA-N |
Cefepime is a fourth-generation cephalosporin antibiotic that acts as a potent inhibitor of bacterial penicillin-binding proteins (PBPs). It covalently binds to PBPs, suppressing transpeptidase activity and interrupting peptidoglycan cross-linking within the bacterial cell wall synthesis pathway. This structural disruption impairs bacterial cell wall integrity, resulting in cell lysis and broad bactericidal activity against diverse Gram-positive and Gram-negative bacterial species. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
96 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.