Azasetron HCl

Catalog No.S2106 Synonyms: Y-25130 HCl

For research use only.

Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.

Azasetron HCl Chemical Structure

CAS No. 123040-16-4

Purity & Quality Control

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Biological Activity

Description Azasetron HCl (Y-25130) is a selective 5-HT3 receptor antagonist with IC50 of 0.33 nM used in the management of nausea and vomiting induced by cancer chemotherapy.
Targets
5-HT3 [1]
0.33 nM

Protocol (from reference)

Solubility (25°C)

In vitro

Water 3 mg/mL
(7.76 mM)
DMSO Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 386.27
Formula

C17H20ClN3O3.HCl

CAS No. 123040-16-4
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CN1C(=O)COC2=C(C=C(C=C21)Cl)C(=O)NC3CN4CCC3CC4.Cl

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

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