Ambroxol

Catalog No.S5710

Ambroxol Chemical Structure

Molecular Weight(MW): 378.10

Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels.

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Biological Activity

Description Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels.

Protocol

References

Solubility (25°C)

In vitro DMSO 76 mg/mL (201.0 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 378.10
Formula

C13H18Br2N2O

CAS No. 18683-91-5
Storage powder
in solvent
Synonyms N/A

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02941822 Active not recruiting Drug: Ambroxol Parkinson Disease University College London|Cure Parkinson''s Trust|PRO.MED.CS Praha a.s - Czech Republic December 2016 Phase 2
NCT02914366 Recruiting Drug: Ambroxol|Other: Placebo Parkinson''s Disease Dementia Lawson Health Research Institute|Weston Brain Institute|University of Western Ontario Canada|London Health Sciences Centre November 2015 Phase 2
NCT02373891 Completed Drug: Surfolase CR Healthy Volunteers Hyundai Pharmaceutical Co. LTD. April 2014 Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

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