Ambroxol
Catalog No.S5710
Molecular Weight(MW): 378.10
Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels.
Purity & Quality Control
Choose Selective Sodium Channel Inhibitors
Biological Activity
| Description | Ambroxol, a substituted benzylamine, is an active metabolite of bromhexine. It is a potent inhibitor of the neuronal Na+ channels. |
|---|
Protocol
References
Solubility (25°C)
| In vitro | DMSO | 76 mg/mL (201.0 mM) |
|---|---|---|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 378.10 |
|---|---|
| Formula | C13H18Br2N2O |
| CAS No. | 18683-91-5 |
| Storage | powder |
| in solvent | |
| Synonyms | N/A |
Bio Calculators
Molarity Calculator
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | interventions | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|---|
| NCT02941822 | Active not recruiting | Drug: Ambroxol | Parkinson Disease | University College London|Cure Parkinson''s Trust|PRO.MED.CS Praha a.s - Czech Republic | December 2016 | Phase 2 |
| NCT02914366 | Recruiting | Drug: Ambroxol|Other: Placebo | Parkinson''s Disease Dementia | Lawson Health Research Institute|Weston Brain Institute|University of Western Ontario Canada|London Health Sciences Centre | November 2015 | Phase 2 |
| NCT02373891 | Completed | Drug: Surfolase CR | Healthy Volunteers | Hyundai Pharmaceutical Co. LTD. | April 2014 | Phase 1 |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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