CAS No. 58-61-7
| IUPAC Name | (2R,3R,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | |
|---|---|---|
| CAS Number | 58-61-7 | |
| Molecular Formula |
C10H13N5O4 |
|
| Molecular Weight (MW) | 267.24 | |
| SMILES | C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N | |
| InChIKey | OIRDTQYFTABQOQ-KQYNXXCUSA-N |
Adenosine is an endogenous purine nucleoside that acts as an agonist for G protein-coupled adenosine receptors, including A1, A2A, A2B, and A3 receptors. Upon elevation during cellular stress, ischemia, or hypoxia, extracellular adenosine activates these receptors to regulate downstream intracellular cAMP signaling pathways. Activation of these receptor pathways modulates inflammatory responses and provides cytoprotection against tissue damage during metabolic stress. [1][2]
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
27 mg/mL
(101.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
12 mg/mL
(44.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
12 mg/mL
(44.9 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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