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Phenytoin Sodium

Name: Phenytoin Sodium
Brand: Selleck Chemicals
SKU: S2524
Rating: 5 (1 reviews)

Synonyms: Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt,Phenytek,Dilantin sodium, Diphantoine

Catalog No.S2524 Purity: 99.99%

Phenytoin Sodium (Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt; Phenytek,Dilantin sodium, Diphantoine) is an inactive voltage-gated sodium channel stabilizer.

Phenytoin Sodium Chemical Structure

CAS: 630-93-3

Selleck's Phenytoin Sodium has been cited by 1 publication

Purity & Quality Control

Batch: Purity: 99.99%

99.99

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Signaling Pathway

Sodium Channel Signaling Pathway

Choose Selective Sodium Channel Inhibitors

Biological Activity

Description

Phenytoin Sodium (Aleviatin, Diphenylhydantoin sodium, Eptoin, Phenytoin soluble, Prompt; Phenytek,Dilantin sodium, Diphantoine) is an inactive voltage-gated sodium channel stabilizer.

Targets

Sodium channel ^[1]

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-01-11)
NCT05884307	Not yet recruiting	Gender Dysphoria	University of Wisconsin Madison	April 2024	Not Applicable
NCT05918887	Not yet recruiting	Tobacco Dependence Caused by Cigarettes	University of Nevada Reno	January 1 2024	Not Applicable
NCT06008496	Not yet recruiting	Pain\|Post Operative Pain\|Opioid Use\|Chronic Pain	University Hospital Plymouth NHS Trust\|National Institute for Academic Anaesthesia\|Newcastle PROMS\|Research and Audit Federation of Anaesthetic Trainees (RAFT)\|University of Plymouth	January 2024	--

Chemical Information & Solubility

Molecular Weight	274.25	Formula	C₁₅H₁₁N₂NaO₂
CAS No.	630-93-3	SDF	Download Phenytoin Sodium SDF
Smiles	C1=CC=C(C=C1)C2(C(=O)[N-]C(=O)N2)C3=CC=CC=C3.[Na+]
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 55 mg/mL ( (200.54 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 5 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
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