Paclitaxel (NSC 125973)

Catalog No.S1150 Synonyms: PTX, Taxol, Onxal, Abraxane

For research use only.

Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

Paclitaxel (NSC 125973) Chemical Structure

CAS No. 33069-62-4

Selleck's Paclitaxel (NSC 125973) has been cited by 336 publications

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Targets
Microtubule (human endothelial cells) [1]
0.1 pM
In vitro

Paclitaxel inhibits non-endothelial type human cells at 104 - to 105 -fold higher concentrations, with IC50 of 1 nM-10 nM. The selectivity of Paclitaxel inhibition of cell proliferation is also species specific, as mouse ECs are not sensitive to Paclitaxel at ultra low concentrations. Inhibition of human ECs by Paclitaxel at ultra low concentrations does not affect the cellular microtubule structure, and the treated cells do not show G2/M cell cycle arrest and apoptosis, suggesting a novel but as yet unidentified mechanism of action. In an in vitro angiogenesis assay, Paclitaxel at ultra low concentrations blocks human ECs from forming sprouts and tubes in the three-dimensional fibrin matrix. [1] In the presence of SMF, the efficient concentration of Paclitaxel on K562 cells is decreased from 50 to 10 ng/mL. The cell cycle arrest effect of Paclitaxel with or without SMF on K562 cells is correlated with DNA damage. [2] Paclitaxel alone causes a time-dependent inhibition of CDK1 in four cell lines including A549 cells, H358, H1395 cells and H1666 cells. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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NCI-H128 NVviNGdqT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXXJR|UxKD1iMUKuNVM{PCEQvF2= NU[0O2tiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
ES7 M1PWSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 M2XBXWlEPTBiPTCxOU4zPDl2IN88US=> NYrrNIZtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
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JVM-3 NH\KVIxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MkDSTWM2OCB;IEKwMlg6QDVizszN MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
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C8166 NWLk[YRwT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M4S3dGlEPTBiPTCyNk4zPzR4IN88US=> NV\GTnp3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
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IM-9 NILMTGlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3TzSmlEPTBiPTCyN{43QTd7IN88US=> MlPUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NH-12 Mor2S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXLkXHhjUUN3MDC9JFI1NjF4NUSg{txO NIexXYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
WSU-NHL NH;v[JdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NUjrd5puUUN3MDC9JFI2Njd{NkGg{txO MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
TUR MYnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M4LYNmlEPTBiPTCyOk43PTN|IN88US=> NF7oN5E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
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KG-1 NWT4cY9rT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MXHJR|UxKD1iMkiuNlg3PSEQvF2= M3;SfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
P31-FUJ M4T6eWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV7JR|UxKD1iMkmuNFQ5QSEQvF2= NWW0eFlERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
NB10 M2e0Smdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NYGycHF{UUN3MDC9JFMyNjVyOTFOwG0> NWLiTYZCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
COLO205 NUnxfIh3S3m2b4TvfIlkcXS7IHHzd4F6 Mkf0S2k2OCB;IECuNFAyPzZizszN MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
SF539 MWPDfZRwfG:6aXPpeJkh[XO|YYm= M1zsT2dKPTBiPTCwMlAxOzZ4IN88US=> MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
SNB75 MoHzR5l1d3SxeHnjbZR6KGG|c3H5 M2\IS2dKPTBiPTCwMlAxQDB6IN88US=> M1OyNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd7MEi5OVAoRjd7MEi5OVA9N2F-
DMS114 NI\xVI5EgXSxdH;4bYNqfHliYYPzZZk> M4DrTWdKPTBiPTCwMlAyOjNizszN NEXRZmk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
OVCAR-3 NXq0VZpMS3m2b4TvfIlkcXS7IHHzd4F6 MmLoS2k2OCB;IECuNFE6PyEQvF2= NFPqb5Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
NCI-H460 M3jremN6fG:2b4jpZ4l1gSCjc4PhfS=> NYPjZmJwT0l3MDC9JFAvODJzOTFOwG0> MoGzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzlyOEm1NEc,PzlyOEm1NFww[T5?
HOP62 Mn7MR5l1d3SxeHnjbZR6KGG|c3H5 MofXS2k2OCB;IECuNFY4OSEQvF2= M3OyW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd7MEi5OVAoRjd7MEi5OVA9N2F-
mammary carcinoma MoK3R5l1d3SxeHnjbZR6KGG|c3H5 MWnJR|UxKD1iMD6yPVkh|ryP M{\kblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzhzOEK2PVgoRjhzOEK2PVg9N2F-
NCI60 NWnNe2xuS3m2b4TvfIlkcXS7IHHzd4F6 M3\p[2dKPTBiPTCwMlAxODZ3IN88US=> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek86PDZzNkWzK|46PDZzNkWzQE9iRg>?
MCF-7 MnzVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2fPWGdKPTBiPTCwMlAxOTFizszN NFjtdFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi97OEezOVk4Lz57OEezOVk4RC:jPh?=
murine leukemic P388 NHH3[3RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnfXS2k2OCB;IECuNFE3KM7:TR?= MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek86QDd|NUm3K|46QDd|NUm3QE9iRg>?
KB MVzDfZRwfG:6aXPpeJkh[XO|YYm= MmTRTWM2OCB;IECuNFA3KM7:TR?= MnHpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTB7N{iyNFAoRjFyOUe4NlAxRC:jPh?=
MCF7 NGDkVFlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MUm3NkBp M2TPOWlEPTBiPTCwMlAxOiEQvF2= MnrUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF|MkWyNlYoRjFzM{K1NlI3RC:jPh?=
MCF-7 MljoR5l1d3SxeHnjbZR6KGG|c3H5 M1vtO2VFPTBiPTCwMlAxPCEQvF2= MnPXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF|M{S1OlcoRjFzM{O0OVY4RC:jPh?=
uterine sarcoma (MES-SA) NHfoenhEgXSxdH;4bYNqfHliYYPzZZk> NXjMUpk4UUN3MDC9JFAvODByMESg{txO NFrkU489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUeyPFE6OSd-MUG3NlgyQTF:L3G+
nonsmall cell lung carcinoma (NCI-H460) NGPH[GhEgXSxdH;4bYNqfHliYYPzZZk> M2WyS2lEPTBiPTCwMlAxODF2IN88US=> M3zRbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzN{K4NVkyLz5zMUeyPFE6OTxxYU6=
colon adenocarcinoma (HT-29) NFTEUnNEgXSxdH;4bYNqfHliYYPzZZk> M1Gzb2lEPTBiPTCwMlAxODF4IN88US=> NXzOWHE{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG3NlgyQTFpPkGxO|I5OTlzPD;hQi=>
prostate carcinoma (DU-145) M3XWOGN6fG:2b4jpZ4l1gSCjc4PhfS=> M3\aNGlEPTBiPTCwMlAxPDh7IN88US=> MoPWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTF5MkixPVEoRjFzN{K4NVkyRC:jPh?=
SW626 NWK0NZU3S3m2b4TvfIlkcXS7IHHzd4F6 M4H2dVczKGh? NV3yVXNqUUN3MDC9JFAvODByMEGg{txO M{D1XVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
Lu1 M1;mWWN6fG:2b4jpZ4l1gSCjc4PhfS=> MWm3NkBp NH3p[pZKSzVyIE2gNE4xOSEQvF2= NIe3PGg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkC4PFQzPSd-MUKwPFg1OjV:L3G+
MCF7 NYfCTIFsS3m2b4TvfIlkcXS7IHHzd4F6 Mom5O|IhcA>? M2KyPWlEPTBiPTCwMlAzKM7:TR?= MnzxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
P388 MX;DfZRwfG:6aXPpeJkh[XO|YYm= M4fEdFczKGh? M4e2SWlEPTBiPTCwMlAzKM7:TR?= MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
LNCAP NYWwV3V7S3m2b4TvfIlkcXS7IHHzd4F6 NILKNm44OiCq M1[y[mlEPTBiPTCwMlAzKM7:TR?= Mn2xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
KB NFywUmpEgXSxdH;4bYNqfHliYYPzZZk> MVm3NkBp NV\TW2d5UUN3MDC9JFAvODJizszN MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
Col2 MYHDfZRwfG:6aXPpeJkh[XO|YYm= MkjKO|IhcA>? Ml6xTWM2OCB;IECuNFIh|ryP MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
BC1 MXPDfZRwfG:6aXPpeJkh[XO|YYm= MkXtO|IhcA>? M4rmW2lEPTBiPTCwMlAzKM7:TR?= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOjB6OESyOUc,OTJyOEi0NlU9N2F-
SK-MEL-2 MXLDfZRwfG:6aXPpeJkh[XO|YYm= MYi3NkBp MnXQTWM2OCB;IECuNFch|ryP M{HTRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
L2987 NGHlW21EgXSxdH;4bYNqfHliYYPzZZk> MoTDTWM2OCB;IECuNkDPxE1? NHjEWYE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkS0N|c5Oyd-MUK0OFM4QDN:L3G+
colon adenocarcinoma RKO NFnvOnBEgXSxdH;4bYNqfHliYYPzZZk> NXvhNY06UUN3MDC9JFAvODFizszN NInjfos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMki1Nlc3QCd-MUK4OVI4Pjh:L3G+
NCI-H460 MW\DfZRwfG:6aXPpeJkh[XO|YYm= M{HmPFQ5KGh? M3;sOmlEPTBiPTCwMlAxQTVizszN NW\reGh1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS2PVU4QThpPkG0Olk2Pzl6PD;hQi=>
MCF7 M1vtcmN6fG:2b4jpZ4l1gSCjc4PhfS=> NYfG[5JqPDhiaB?= Mn3TTWM2OCB;IECuNFEyOiEQvF2= MlXBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR4OUW3PVgoRjF2Nkm1O|k5RC:jPh?=
SF268 NIfNUmJEgXSxdH;4bYNqfHliYYPzZZk> Mn2zOFghcA>? M1TpdmlEPTBiPTCwMlAzOTdizszN Mn\oQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR4OUW3PVgoRjF2Nkm1O|k5RC:jPh?=
MDA-MB-231 NU\m[otvS3m2b4TvfIlkcXS7IHHzd4F6 M1K4fFQ5KGh? NF7EV4tKSzVyIE2gNE4xODR3IN88US=> MlGzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR7OEewOVEoRjF2OUi3NFUyRC:jPh?=
MCF7 M4rj[GN6fG:2b4jpZ4l1gSCjc4PhfS=> MnX2OFghcA>? Mn;HTWM2OCB;IECuNFA1QSEQvF2= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
A2780 MVfDfZRwfG:6aXPpeJkh[XO|YYm= Mo\6OFghcA>? NWnxco1WUUN3MDC9JFAvODJ3IN88US=> NXnn[IJWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS5PFcxPTFpPkG0PVg4ODVzPD;hQi=>
PC3 M4fT[GN6fG:2b4jpZ4l1gSCjc4PhfS=> NXjqS5VZPDhiaB?= NI\mXohKSzVyIE2gNE4xPzdizszN MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1NUc,OTR7OEewOVE9N2F-
MCF7 MYrDfZRwfG:6aXPpeJkh[XO|YYm= MVO3NkBp NHfpNFFKSzVyIE2gNE4xODF2IN88US=> MoK2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR7OEewOVYoRjF2OUi3NFU3RC:jPh?=
multidrug-resistant MCF7 MorHR5l1d3SxeHnjbZR6KGG|c3H5 MWO3NkBp NGTZZZpKSzVyIE2gNE4{PTRizszN MkDIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR7OEewOVYoRjF2OUi3NFU3RC:jPh?=
PC3 MlzHR5l1d3SxeHnjbZR6KGG|c3H5 MVe0PEBp M3m4dGlEPTBiPTCwMlAyPiEQvF2= M2fudFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFAzLz5zNUC0N|QxOjxxYU6=
Hep3B MnHlR5l1d3SxeHnjbZR6KGG|c3H5 MWK0PEBp MVnJR|UxKD1iMD6wN|Eh|ryP MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwNkc,OTVyNEO0NFI9N2F-
NCI-H460 MV3DfZRwfG:6aXPpeJkh[XO|YYm= MV[0PEBp NVXNZXo{UUN3MDC9JFAvODB7NTFOwG0> M4DHN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFA1Lz5zNUC0N|QxPDxxYU6=
MCF7 NVPxOWxPS3m2b4TvfIlkcXS7IHHzd4F6 NYe5[3V[PDhiaB?= NX30XZZLUUN3MDC9JFAvODFzMjFOwG0> NWfJTZZ1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODRpPkG1NFQ{PDB2PD;hQi=>
SF268 MlWzR5l1d3SxeHnjbZR6KGG|c3H5 MlnOOFghcA>? NYDPSZZZUUN3MDC9JFAvODJzNzFOwG0> MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTB2M{SwOEc,OTVyNEO0NFQ9N2F-
KB NHfkWmxEgXSxdH;4bYNqfHliYYPzZZk> MlnaSWQ2OCB;IECuNFAxPCEQvF2= NXvhcpRCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
Lu1 MVHDfZRwfG:6aXPpeJkh[XO|YYm= NXfkTFh{TUR3MDC9JFAvODB{IN88US=> NV\qNmFrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
LNCAP MYDDfZRwfG:6aXPpeJkh[XO|YYm= NXr5XVQzTUR3MDC9JFAvODB3IN88US=> MnnRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFcoRjF3MESzOFA4RC:jPh?=
RPE1 M{HYRWN6fG:2b4jpZ4l1gSCjc4PhfS=> MofGSWQ2OCB;IECuNFI{KM7:TR?= M1HNV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3MESzOFA4Lz5zNUC0N|QxPzxxYU6=
Col2 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MXzFSFUxKD1iMD6wOFYh|ryP MnfiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFcoRjF3MESzOFA4RC:jPh?=
T47D M4XoZ2Fxd3C2b4Ppd{Bie3OjeR?= M1PadFI1KGh? NWfzO5lnTUN3MDC9JFAvODNizszN MoSwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV3Nk[zNFAoRjF3NU[2N|AxRC:jPh?=
DLD1 MnPrRZBweHSxc3nzJIF{e2G7 M1T0XFI1KGh? MnrzSWM2OCB;IECuNFc2KM7:TR?= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTV4NkOwNEc,OTV3Nk[zNFA9N2F-
H1299 MXzBdI9xfG:|aYOgZZN{[Xl? NVnjb3JsOjRiaB?= MUPFR|UxKD1iMD6xOlMh|ryP M2GxVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3NU[2N|AxLz5zNUW2OlMxODxxYU6=
VA13 M{TONmN6fG:2b4jpZ4l1gSCjc4PhfS=> MX60PEBp M{jVXmlEPTBiPTCwMlAxPSEQvF2= MnTyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV5M{CyOFMoRjF3N{OwNlQ{RC:jPh?=
WI 38 NG[wbmVEgXSxdH;4bYNqfHliYYPzZZk> NXfK[IhHPDhiaB?= NFmxUGNKSzVyIE2gNE4xPCEQvF2= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd|MEK0N{c,OTV5M{CyOFM9N2F-
Hep G2 NEnRdo5EgXSxdH;4bYNqfHliYYPzZZk> Mo\hOFghcA>? NG\K[3pKSzVyIE2gPE4yKM7:TR?= NVTkdoVsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3N|AzPDNpPkG1O|MxOjR|PD;hQi=>
A549 NVGx[XFMS3m2b4TvfIlkcXS7IHHzd4F6 MnL0OFghcA>? NEDtRpNKSzVyIE2gNU4zPSEQvF2= M4HPXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{i3OFYxLz5zNUe4O|Q3ODxxYU6=
SKOV3 NYfITHlnS3m2b4TvfIlkcXS7IHHzd4F6 NHi0Spk1QCCq NUnpdWkyUUN3MDC9JFEvOzVizszN NWLjOYJLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUW3PFc1PjBpPkG1O|g4PDZyPD;hQi=>
KB M{PvUmN6fG:2b4jpZ4l1gSCjc4PhfS=> MVKzJIRigXN? M1TmSWlEPTBiPTCwMlAxOSEQvF2= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjB|OEW0OUc,OTZyM{i1OFU9N2F-
1A9 NEP1V4FEgXSxdH;4bYNqfHliYYPzZZk> MlXwN{Bl[Xm| M3zXUGlEPTBiPTCwMlAxOiEQvF2= M2PYWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4MEO4OVQ2Lz5zNkCzPFU1PTxxYU6=
HCT8 MnjKR5l1d3SxeHnjbZR6KGG|c3H5 M1XiU|Mh\GG7cx?= MnjOTWM2OCB;IECuNFE{KM7:TR?= NVO0W4ZDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[wN|g2PDVpPkG2NFM5PTR3PD;hQi=>
A431 MX3D[YxtKGO7Y3zlJIFzemW|dDDhd5NigQ>? MVXFR|UxKD1iMD6wNFkh|ryP MnPHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ|N{exPFcoRjF4M{e3NVg4RC:jPh?=
VA13 MWLHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVW0PEBp MX3JR|UxKD1iMD6wNFQ{KM7:TR?= MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjR7OUOyNkc,OTZ2OUmzNlI9N2F-
WI38 MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M3rEb|Q5KGh? NXvwWGlFUUN3MDC9JFAvODN2IN88US=> M1WzeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEm5N|IzLz5zNkS5PVMzOjxxYU6=
HepG2 NHX3c2RIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NWL5SopSPDhiaB?= MYfJR|UxKD1iNj65JO69VQ>? M2TYUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEm5N|IzLz5zNkS5PVMzOjxxYU6=
Aro M33QbGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVXGSmN7UUN3MDC9JFAvODByMjFOwG0> MlHuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
PT45 MoXkR5l1d3SxeHnjbZR6KGG|c3H5 NXGxeFl2UUN3MDC9JFAvODB3IN88US=> MojYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
A549 M2f1OWN6fG:2b4jpZ4l1gSCjc4PhfS=> MV3JR|UxKD1iMD6wNFYh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
MCF7 M{L4cWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXLJR|UxKD1iMD6wNFch|ryP MnH0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
HeLa MmG4R5l1d3SxeHnjbZR6KGG|c3H5 MXTJR|UxKD1iMD6wNFgh|ryP M3Lo[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
Ovcar3 NXrJS5c3S3m2b4TvfIlkcXS7IHHzd4F6 MoLjTWM2OCB;IECuNFEh|ryP NHno[|g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
HT29 M3O0emN6fG:2b4jpZ4l1gSCjc4PhfS=> NH7HdJBKSzVyIE2gNE4xPSEQvF2= M4HYVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
H295R NFzQSoZEgXSxdH;4bYNqfHliYYPzZZk> MYHJR|UxKD1iMD6wPEDPxE1? NUWyZZJVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
BNL M4jZVWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXixPGV3UUN3MDC9JFAvOiEQvF2= NH3VTnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
4T1 MoPHR5l1d3SxeHnjbZR6KGG|c3H5 MYPJR|UxKD1iMD6yJO69VQ>? M2\KdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
HepG2 MUPDfZRwfG:6aXPpeJkh[XO|YYm= MmXFTWM2OCB;IECuN{DPxE1? M3nMWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
U937 GTB MoTjR5l1d3SxeHnjbZR6KGG|c3H5 NG\0ZpU4OiCq MUPJR|UxKD1iMD6wNFU6KM7:TR?= M{\Sd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NU[yPFQxLz5zNkW2Nlg1ODxxYU6=
RPMI 8226/s MX7DfZRwfG:6aXPpeJkh[XO|YYm= MVe3NkBp MWXJR|UxKD1iMD6wNFch|ryP MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV4Mki0NEc,OTZ3NkK4OFA9N2F-
CEM/s NH3GZppEgXSxdH;4bYNqfHliYYPzZZk> MnTWO|IhcA>? MYHJR|UxKD1iMD6wNFch|ryP M2jYR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NU[yPFQxLz5zNkW2Nlg1ODxxYU6=
VA13 NU\tdXpvS3m2b4TvfIlkcXS7IHHzd4F6 NXO0fIk2UUN3MDC9JFAvODB3OTFOwG0> MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjd{NEi0Nkc,OTZ5MkS4OFI9N2F-
WI38 MWnDfZRwfG:6aXPpeJkh[XO|YYm= Ml7kTWM2OCB;IECuNFQ3QCEQvF2= NW\PPWFtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3NlQ5PDJpPkG2O|I1QDR{PD;hQi=>
HepG2 MkfJR5l1d3SxeHnjbZR6KGG|c3H5 NESxd21KSzVyIE2gPU41QSEQvF2= M1nQclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4N{K0PFQzLz5zNkeyOFg1OjxxYU6=
HT29 MlLXR5l1d3SxeHnjbZR6KGG|c3H5 NGPwdHdGSzVyIE2gNE4xODZizszN NYK4dXhORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[4O|A1OjhpPkG2PFcxPDJ6PD;hQi=>
K562 M1fQPGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlPOSWM2OCB;IECuNFE1KM7:TR?= Mn\oQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ6N{C0NlgoRjF4OEewOFI5RC:jPh?=
MCF7 NInBdI9EgXSxdH;4bYNqfHliYYPzZZk> NH\lepVGSzVyIE2gNE4xOzZizszN NXrISmV[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[4O|A1OjhpPkG2PFcxPDJ6PD;hQi=>
VA-13 NXvKWVMxS3m2b4TvfIlkcXS7IHHzd4F6 M{myS2lEPTBiPTCwMlAxPSEQvF2= M3XRSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4OUOzPFY5Lz5zNkmzN|g3QDxxYU6=
WI38 M1TrZmN6fG:2b4jpZ4l1gSCjc4PhfS=> NXrvPYdjUUN3MDC9JFAvODRizszN NXLldINiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5N|M5PjhpPkG2PVM{QDZ6PD;hQi=>
VA13 NX3PN5dTS3m2b4TvfIlkcXS7IHHzd4F6 NGT3RolKSzVyIE2gNE4xODVizszN M4n3cFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5ME[3NVU2Lz5zN{C2O|E2PTxxYU6=
WI38 MlPGR5l1d3SxeHnjbZR6KGG|c3H5 MVXJR|UxKD1iMD6wOEDPxE1? MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzB4N{G1OUc,OTdyNkexOVU9N2F-
Hep G2 NHTrZ2tEgXSxdH;4bYNqfHliYYPzZZk> NEHCXlVKSzVyIE2gPE4yKM7:TR?= MkDIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdyNkexOVUoRjF5ME[3NVU2RC:jPh?=
TW01 NGDzenJEgXSxdH;4bYNqfHliYYPzZZk> M2HEVmlEPTBiPTCwMlAxODNizszN M1OzVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
MCF7 NWPGdlQ6S3m2b4TvfIlkcXS7IHHzd4F6 MkPmTWM2OCB;IECuNFAxPSEQvF2= MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
MKN45 M{DXSWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYXtNYVMUUN3MDC9JFAvODByNTFOwG0> NXHBXpVJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexNVMzQDhpPkG3NVE{Ojh6PD;hQi=>
MES-SA M2PCTmN6fG:2b4jpZ4l1gSCjc4PhfS=> MW\JR|UxKD1iMD6wNFA2KM7:TR?= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
HCT116 MX3DfZRwfG:6aXPpeJkh[XO|YYm= MXfJR|UxKD1iMD6wNFA3KM7:TR?= M4jIb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
RPTEC NUO1XoQ4S3m2b4TvfIlkcXS7IHHzd4F6 NFLGT3VKSzVyIE2gNE4xODB7IN88US=> NEXT[5g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
Hep3B NGL6WZREgXSxdH;4bYNqfHliYYPzZZk> NWHlXFVbUUN3MDC9JFAvODB3NDFOwG0> NFXY[ZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
NCI-H226 NYHEbHUyS3m2b4TvfIlkcXS7IHHzd4F6 Mn\xTWM2OCB;IECuNFA3QCEQvF2= NEm0ZWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
A498 NYnzNIlKS3m2b4TvfIlkcXS7IHHzd4F6 MkjWTWM2OCB;IECuNFYyKM7:TR?= MoXBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
MDA435/LCC6 M4W4RWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NVvaSFFkUUN3MDC9JFAvODB{OTFOwG0> M1fRb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUW0OVA2Lz5zN{G1OFUxPTxxYU6=
multidrug resistant MDA435/LCC6 M{joR2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MoWyTWM2OCB;IECuNFA1QCEQvF2= MlvXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzNUS1NFUoRjF5MUW0OVA2RC:jPh?=
P388 Mn3rRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NEDBTlBKSzVyIE2gNE4xOjJizszN MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF3NEWwOUc,OTdzNUS1NFU9N2F-
adriamycin resistant P388 NVLHdoVCSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Mli3TWM2OCB;IECuNFMh|ryP M1rVRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUW0OVA2Lz5zN{G1OFUxPTxxYU6=
LT12 NXHHWVk6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYG0PEBp MU\JR|UxKD1iMD6wNFYh|ryP NYiyZo97RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
SKOV3 MULBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MVe0PEBp NES1VFdKSzVyIE2gNE4xOSEQvF2= NH;JfHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
NCI-H460 M2XacGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MonQOFghcA>? NV\leXd5UUN3MDC9JFAvODFizszN MmPLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
SF268 MU\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M4[0cVQ5KGh? M2rwe2lEPTBiPTCwMlAyKM7:TR?= MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
RKO NYjyOIVKSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3\GTVQ5KGh? MmL3TWM2OCB;IECuNFEh|ryP MkX6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
KB/HeLa NWq1SnJuSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NIDL[2s1QCCq Mni1TWM2OCB;IECuNFEh|ryP MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
P388 MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MlH0OFghcA>? MmTyTWM2OCB;IECuNFQh|ryP M2\6SVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUixNVY1Lz5zN{G4NVE3PDxxYU6=
L1210 NHq1bVBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NYjGdVZIPDhiaB?= MXjJR|UxKD1iMD6wOkDPxE1? MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
LT12 MDR NFLLWXBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MoT4OFghcA>? NXXPSGhDUUN3MDC9JFAvPCEQvF2= Mnn3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
A2780 M4nCWGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWG2Z|lxUUN3MDC9JFAvODBzIN88US=> NYX0dWVnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNFYyOzlpPkG3NlA3OTN7PD;hQi=>
A2780-1A9 NULZU4dFS3m2b4TvfIlkcXS7IHHzd4F6 MVHJR|UxKD1iMD6wNFEyKM7:TR?= M{LCUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
A549 M{DVWGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVvYRXRNUUN3MDC9JFAvODB|NjFOwG0> NHLROVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
1A9PTX22 NYnMUo5TS3m2b4TvfIlkcXS7IHHzd4F6 M33PVWlEPTBiPTCwMlAyQSEQvF2= NHi3c4Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
1A9PTX10 NWLpb4tFS3m2b4TvfIlkcXS7IHHzd4F6 NI[zOWlKSzVyIE2gNE4xOyEQvF2= NIjuWYQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
A2780AD NUjndVZJS3m2b4TvfIlkcXS7IHHzd4F6 MVPJR|UxKD1iMD65JO69VQ>? M2D2[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
KB MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M3vjU2lEPTBiPTCwMlAxOjR3IN88US=> M2jKclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkK4PFc{Lz5zN{KyPFg4OzxxYU6=
COLO205 MWHDfZRwfG:6aXPpeJkh[XO|YYm= MU\JR|UxKD1iMD6wNFM{KM7:TR?= M3S4PFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkK4PFc{Lz5zN{KyPFg4OzxxYU6=
KB8.5 NX;CdnpFSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MUTJR|UxKD1iMD6wNlYh|ryP MnP6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{Mki4O|MoRjF5MkK4PFc{RC:jPh?=
KBV1 NIDIeIFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NVX1bnZbUUN3MDC9JFIvODF|IN88US=> MoLoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{Mki4O|MoRjF5MkK4PFc{RC:jPh?=
A2780 NYTlNI1pS3m2b4TvfIlkcXS7IHHzd4F6 M{T4bmlEPTBiPTCwMlAxODdizszN M4niOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkO5OVk4Lz5zN{KzPVU6PzxxYU6=
2780AD NV7rUIk6S3m2b4TvfIlkcXS7IHHzd4F6 M1faWmlEPTBiPTCwMlU{PSEQvF2= NE[0TYg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KzPVU6Pyd-MUeyN|k2QTd:L3G+
1A9 M1mz[2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYDFSFUxKD1iMD6wNFEh|ryP NGDNXok9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O1NFg{PCd-MUezOVA5OzR:L3G+
MCF7 M4XUfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NV7WUXE1TUR3MDC9JFAvODBzMTFOwG0> MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN3MEizOEc,OTd|NUC4N|Q9N2F-
DU145 MlHVR5l1d3SxeHnjbZR6KGG|c3H5 NE\zdmtGTDVyIE2gNE4xODF|IN88US=> M2XpOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
KB NXjWXHZ5S3m2b4TvfIlkcXS7IHHzd4F6 NVHXUmVCTUR3MDC9JFAvODBzODFOwG0> NXjhOIxzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
A549 NW\oXmFOS3m2b4TvfIlkcXS7IHHzd4F6 NWj2PIM3TUR3MDC9JFAvODB{MzFOwG0> NILmdIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O1NFg{PCd-MUezOVA5OzR:L3G+
LNCAP MlTzR5l1d3SxeHnjbZR6KGG|c3H5 NFv2ZlJGTDVyIE2gNE4xODJ4IN88US=> NVXMTVVORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
PC3 NYfmSplsS3m2b4TvfIlkcXS7IHHzd4F6 NHnSV2xGTDVyIE2gNE4xPTV3IN88US=> NV\2emF2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUezOVA5OzRpPkG3N|UxQDN2PD;hQi=>
KBVIN M2LmbGN6fG:2b4jpZ4l1gSCjc4PhfS=> NHzhWo1GTDVyIE2gNE4{OTFizszN MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN3MEizOEc,OTd|NUC4N|Q9N2F-
A2780 MWXDfZRwfG:6aXPpeJkh[XO|YYm= MUXJR|UxKD1iMD6wNFE3KM7:TR?= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN7NUS2OUc,OTd|OUW0OlU9N2F-
A2780/AD MVTDfZRwfG:6aXPpeJkh[XO|YYm= NFm2O5NKSzVyIE2gNE46OiEQvF2= M2PCN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{m1OFY2Lz5zN{O5OVQ3PTxxYU6=
KB M1rCZ2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NX7pdG5XUUN3MDC9JFAvODB{NEWg{txO M3zoZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG2OVI1Lz5zN{SxOlUzPDxxYU6=
COLO205 MUjDfZRwfG:6aXPpeJkh[XO|YYm= NWDIU4g1UUN3MDC9JFAvODB|MzFOwG0> MmPCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MU[1NlQoRjF5NEG2OVI1RC:jPh?=
KB8.5 M37IVGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MoX6TWM2OCB;IECuNFI3KM7:TR?= NFXFcZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxOlUzPCd-MUe0NVY2OjR:L3G+
KBV1 M1Tr[2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M4LISGlEPTBiPTCyMlAyOyEQvF2= NWDaRlJPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVY2OjRpPkG3OFE3PTJ2PD;hQi=>
neural precursor NIPCTpVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MmPqSWM2OCB;IECuNFEh|ryP MkW5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUe2N|EoRjF5NEG3OlMyRC:jPh?=
OVCAR-3 NYD3OXZNS3m2b4TvfIlkcXS7IHHzd4F6 M{fEOGlEPTBiPTCwMlAxODJizszN M3uyPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
MDA-MB-231 MULDfZRwfG:6aXPpeJkh[XO|YYm= M{D1fGlEPTBiPTCwMlAxPDVizszN MoTjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUmwOlUoRjF5NEG5NFY2RC:jPh?=
MCF7 MmPZR5l1d3SxeHnjbZR6KGG|c3H5 NIK2dldKSzVyIE2gNE4xODR7IN88US=> NE\pW5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
NCI-H1299 NWXSXZJLS3m2b4TvfIlkcXS7IHHzd4F6 MVu5OkBp MnnKTWM2OCB;IECuNFE2KM7:TR?= MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
A2780 MlrBR5l1d3SxeHnjbZR6KGG|c3H5 NXv4OYRoUUN3MDC9JFAvODJ3IN88US=> M1roc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
PC3 MXXDfZRwfG:6aXPpeJkh[XO|YYm= Moe1TWM2OCB;IECuNFc4KM7:TR?= NGf6[Y09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxPVA3PSd-MUe0NVkxPjV:L3G+
LoVo MmnTR5l1d3SxeHnjbZR6KGG|c3H5 NEDZZmNKSzVyIE2gNE4xQSEQvF2= M1m3eFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
L2987 NIfhXJhEgXSxdH;4bYNqfHliYYPzZZk> M1nHPGlEPTBiPTCwMlIh|ryP MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
cells NGPudYxEgXSxdH;4bYNqfHliYYPzZZk> MX3JR|UxKD1iMD6wNFU6KM7:TR?= NX3VOpV6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFI2PzdpPkG3OFQzPTd5PD;hQi=>
cells NHm3eHNEgXSxdH;4bYNqfHliYYPzZZk> MkLLTWM2OCB;IECuNFEh|ryP M4jLXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEi1NlA4Lz5zN{S4OVIxPzxxYU6=
A2780 NXS4T5B6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIKyUFFKSzVyIE2gNE4xODJ6IN88US=> NFzicIU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5NFg4QCd-MUe0PVA5Pzh:L3G+
VA13 NXHiR4E1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXHJR|UxKD1iMD6wNFUh|ryP NUXOO2c5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
WI38 NX;idVRjT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{PaUGlEPTBiPTCwMlA1KM7:TR?= M17YcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEmwPFc5Lz5zN{S5NFg4QDxxYU6=
2780AD MV;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NH7XXoFKSzVyIE2gNE4yQDNizszN M4rBNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEmwPFc5Lz5zN{S5NFg4QDxxYU6=
HepG2 M4nm[mdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWT0SG1wUUN3MDC9JFgvOSEQvF2= NYDlSmZ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
HT29 MXTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MoPxOFghcA>? NUj1W2wxT0l3MDC9JFAvODF3IN88US=> MmDxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
M21 NEDIdIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M{juT|Q5KGh? MYPHTVUxKD1iMD6wN|ch|ryP NVHzZ3FiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVg6PjBpPkG3OFk5QTZyPD;hQi=>
MCF7 M3rGZ2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVe0PEBp M3HYSWdKPTBiPTCwMlA2PCEQvF2= MlvwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
1A9 MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVe3NkBp Mnz2S2k2OCB;IECuNFAxPzFizszN MkXPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEK1O|IoRjF5NUSyOVczRC:jPh?=
1A9/Ptx22 MYjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGLyblE4OiCq NISyNHhIUTVyIE2gNE4xPTFizszN M3nP[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUSyOVczLz5zN{W0NlU4OjxxYU6=
1A9/Ptx10 MX\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mm\zO|IhcA>? Mn62S2k2OCB;IECuNFY1KM7:TR?= Ml6xQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NEK1O|IoRjF5NUSyOVczRC:jPh?=
cells expressing MRP1 MXfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NV\OfFl6UUN3MDC9JFAvODB{NTFOwG0> NGTnXpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W2O|EzOSd-MUe1OlcyOjF:L3G+
cells expressing Pgp/MRP1 NUPU[JNsT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NX\2e|A3UUN3MDC9JFIvPyEQvF2= NFnFSpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W2O|EzOSd-MUe1OlcyOjF:L3G+
VA13 M3v5TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHLhTWZKSzVyIE2gOUDPxE1? M330V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUm1NVM1Lz5zN{W5OVE{PDxxYU6=
MCF7 NHm5OWhHfW6ldHnvckBie3OjeR?= M3G3Z2lEPTBiPTCwMlAxOThizszN NXPUcY5QRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2NFE4OzlpPkG3OlAyPzN7PD;hQi=>
adriamycin-resistant MCF7 NGPwd2pHfW6ldHnvckBie3OjeR?= MXLJR|UxKD1iOD6yJO69VQ>? NWnYU2FnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2NFE4OzlpPkG3OlAyPzN7PD;hQi=>
RPMI8226 NEDrXoREgXSxdH;4bYNqfHliYYPzZZk> MlTYS2k2OCB;IECuNFAzKM7:TR?= NHvSPFE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
HT29 NEPLeGxEgXSxdH;4bYNqfHliYYPzZZk> MXPHTVUxKD1iMD6wNFIh|ryP NVzQ[WZ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
COLO205 NVPsbYUzS3m2b4TvfIlkcXS7IHHzd4F6 NGnUS3FIUTVyIE2gNE4xODNizszN NYq0cVRuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
HCC2998 MWXDfZRwfG:6aXPpeJkh[XO|YYm= NUXhSFNNT0l3MDC9JFAvODB|IN88US=> NXfRZmtFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
HS578T NIraUVFEgXSxdH;4bYNqfHliYYPzZZk> M{\kTmdKPTBiPTCwMlAxOyEQvF2= NWjDO3dPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
PC3 M3rxXGN6fG:2b4jpZ4l1gSCjc4PhfS=> NH2zPW1IUTVyIE2gNE4xODRizszN NVLucoNZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
SNB75 NFPYNnBEgXSxdH;4bYNqfHliYYPzZZk> M4fWfGdKPTBiPTCwMlAxPCEQvF2= M3zQbVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
A549 NHi0eG1EgXSxdH;4bYNqfHliYYPzZZk> NH\ZSmlIUTVyIE2gNE4xODRizszN NUfQcWRJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
KM12 MW\DfZRwfG:6aXPpeJkh[XO|YYm= NGHpN2pIUTVyIE2gNE4xODRizszN M2nuZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
DU145 MYnDfZRwfG:6aXPpeJkh[XO|YYm= MVTHTVUxKD1iMD6wNFUh|ryP MnfJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
SK-OV3 M4Xid2N6fG:2b4jpZ4l1gSCjc4PhfS=> M2j4WGdKPTBiPTCwMlAxQCEQvF2= NEHSOGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
NCI-H322M NImxRolEgXSxdH;4bYNqfHliYYPzZZk> NF61XWpIUTVyIE2gNE4xOTNizszN M3HaOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5Nkm2N|MzLz5zN{[5OlM{OjxxYU6=
UACC257 MUPDfZRwfG:6aXPpeJkh[XO|YYm= MlzZS2k2OCB;IECuNFQh|ryP NGHBOog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
HCT15 MULDfZRwfG:6aXPpeJkh[XO|YYm= NVriXW9ZT0l3MDC9JFAvOTV6IN88US=> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
ACHN M1:3cGN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml;FS2k2OCB;IECuN|k5KM7:TR?= Ml;GQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
HeLa NFvSU|BEgXSxdH;4bYNqfHliYYPzZZk> NHTJe5JKSzVyIE2gNE4xODV4IN88US=> M2fzSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5N{[0NVQ5Lz5zN{e2OFE1QDxxYU6=
MCF7 MofVR5l1d3SxeHnjbZR6KGG|c3H5 MWfJR|UxKD1iMD6wNVI1KM7:TR?= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzd4NEG0PEc,OTd5NkSxOFg9N2F-
A549 MnT6R5l1d3SxeHnjbZR6KGG|c3H5 MX\JR|UxKD1iMD6wNVI3KM7:TR?= NIW1dog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{e2OFE1QCd-MUe3OlQyPDh:L3G+
HGC27 NIPodIZEgXSxdH;4bYNqfHliYYPzZZk> M4TrR2lEPTBiPTCwMlc4PzhizszN MkXTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd5NkSxOFgoRjF5N{[0NVQ5RC:jPh?=
HL60 NXO2XWt5S3m2b4TvfIlkcXS7IHHzd4F6 MmTyO|IhcA>? NU\mPGhtUUN3MDC9JFAvQTNizszN M4[wZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEm2PFE3Lz5zN{i5OlgyPjxxYU6=
P388 MWPDfZRwfG:6aXPpeJkh[XO|YYm= M4rwUlczKGh? NG\sRoxKSzVyIE2gNE46OyEQvF2= M3LQd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OEm2PFE3Lz5zN{i5OlgyPjxxYU6=
BEL-7402 M1;PT2N6fG:2b4jpZ4l1gSCjc4PhfS=> MWCyOEBp MWDJR|UxKD1iMD65N{DPxE1? Mn24QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd6OU[4NVYoRjF5OEm2PFE3RC:jPh?=
A459 MkjjR5l1d3SxeHnjbZR6KGG|c3H5 NEnye5czPCCq NH;YZ2VKSzVyIE2gNE46OyEQvF2= Ml;WQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd6OU[4NVYoRjF5OEm2PFE3RC:jPh?=
HeLa NFTBd|hEgXSxdH;4bYNqfHliYYPzZZk> MV;JR|UxKD1iMD6wNkDPxE1? MmDlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUGwNVcoRjF5OUGxNFE4RC:jPh?=
HepG2 M2WwcmN6fG:2b4jpZ4l1gSCjc4PhfS=> MmLNTWM2OCB;IECuPFIh|ryP M1rSO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUGxNFE4Lz5zN{mxNVAyPzxxYU6=
BGC823 M2r4bGN6fG:2b4jpZ4l1gSCjc4PhfS=> MUTJR|UxKD1iMT6xOUDPxE1? M3;h[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUGxNFE4Lz5zN{mxNVAyPzxxYU6=
Aro MoHLR5l1d3SxeHnjbZR6KGG|c3H5 NFT4WYc4OiCq MnvjTWM2OCB;IECuNFAxOiEQvF2= M2eyUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
PT45 NGf0RnZEgXSxdH;4bYNqfHliYYPzZZk> M17SOlczKGh? MoS4TWM2OCB;IECuNFA2KM7:TR?= MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
A549 NVL3RXVyS3m2b4TvfIlkcXS7IHHzd4F6 NITBVZU4OiCq NFThXGlKSzVyIE2gNE4xODZizszN NELxT2E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
MCF7 NEG2SXJEgXSxdH;4bYNqfHliYYPzZZk> NY\seJRuPzJiaB?= NWLTO4V[UUN3MDC9JFAvODB5IN88US=> M4rBdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
HeLa M2DONWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2XHdVczKGh? NX3zVlBxUUN3MDC9JFAvODB6IN88US=> M4f6XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
Ovcar3 Mli3R5l1d3SxeHnjbZR6KGG|c3H5 MUm3NkBp Mnr2TWM2OCB;IECuNFEh|ryP M1r5WlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
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H295R M4POU2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoHCO|IhcA>? NFWwOVRKSzVyIE2gNE4xQCEQvF2= NIe0SpA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
A549T24 MWTDfZRwfG:6aXPpeJkh[XO|YYm= M1\1WFczKGh? M4LGWWlEPTBiPTCwMlExOiEQvF2= MnywQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
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HepG2 NGDqSXpEgXSxdH;4bYNqfHliYYPzZZk> MV:3NkBp NVvycmdKUUN3MDC9JFAvOyEQvF2= M4\pOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
OE19 MVTDfZRwfG:6aXPpeJkh[XO|YYm= MV23NkBp MUHJR|UxKD1iMD60JO69VQ>? MmnRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
L12 M1f1W2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M1n0TlQ5KGh? NIDRPWVKSzVyIE2gNE4xODZizszN MlzoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
NCI-H460 M{TudWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYDZPXExPDhiaB?= NGPzRplKSzVyIE2gNE4xOSEQvF2= M1y1NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUezN|YyLz5zN{m3N|M3OTxxYU6=
SKOV3 NGTF[HZEgXSxdH;4bYNqfHliYYPzZZk> NVrkcpBmPDhiaB?= NHHLZlhKSzVyIE2gNE4xOSEQvF2= NHmzfZQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
SF268 M{jjeGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGPYTXc1QCCq MkH5TWM2OCB;IECuNFEh|ryP NHq2fnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
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cells assessed as accumulation at G2/M phase after 24 hrs by flow cytometric analysis NF;hNopE\WyuIHP5Z4xmKGG{cnXzeEBie3OjeR?= NEKzdJNGSzVyIE2gNE4xPDlizszN MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
L1210 M3\0V2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NF3h[YM1QCCq NYP4T4RLUUN3MDC9JFAvODZizszN NHPXe3Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
cells after 48 hrs by XTT assay MXLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MVHJR|UxKD1iMD60JO69VQ>? NHP0c2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
A2780 MWLDfZRwfG:6aXPpeJkh[XO|YYm= Mn\STWM2OCB;IECuNFA3OyEQvF2= NFfkfJY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOECwNVA5Pyd-MUiwNFExQDd:L3G+
BGC823 MlixR5l1d3SxeHnjbZR6KGG|c3H5 NYDzdYd2UUN3MDC9JFAvODB5IN88US=> MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDByMUC4O{c,OThyMEGwPFc9N2F-
A549 M4rBWmN6fG:2b4jpZ4l1gSCjc4PhfS=> M33TWWlEPTBiPTCwMlAyQSEQvF2= NUL0e3pURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwNFExQDdpPkG4NFAyODh5PD;hQi=>
HCT8 NV60SI5xS3m2b4TvfIlkcXS7IHHzd4F6 NET0dGhKSzVyIE2gNE4xOzdizszN MnH4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
Bel7402 M{O2SmN6fG:2b4jpZ4l1gSCjc4PhfS=> NICzbZdKSzVyIE2gNE4yKM7:TR?= Mkj2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
cells by alamar blue assay NXT1[XNsTnWwY4Tpc44h[XO|YYm= M4fTR2lEPTBiPTCwMlA1KM7:TR?= MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDB5MEm2OUc,OThyN{C5OlU9N2F-
PANC1 M2XSSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHP1UlU4OiCq MX;JR|UxKD1iMD6wNFch|ryP NX;Ic2NPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwPFEzPTdpPkG4NFgyOjV5PD;hQi=>
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NCI/ADR M4HxfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MW[3NkBp NVvobIxsUUN3MDC9JFEh|ryP MmHGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyOEGyOVcoRjF6MEixNlU4RC:jPh?=
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A2780 NXXLPVV6SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NFvncJA6PiCq Ml;RTWM2OCB;IECuNFI{PCEQvF2= NWnyUHVORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUixO|cxOTRpPkG4NVc4ODF2PD;hQi=>
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HCT116 Mkn1RZBweHSxc3nzJIF{e2G7 NY[0UoZEOjRiaB?= NWHXRYhITUN3MDC9JFAvODJ2IN88US=> M1L1eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MUm3OlE1Lz5zOEG5O|YyPDxxYU6=
T47D NED3b4NCeG:ydH;zbZMh[XO|YYm= MYKyOEBp NFXScmhGSzVyIE2gNE4xOzZizszN M3rocVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MUm3OlE1Lz5zOEG5O|YyPDxxYU6=
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P388 NUXSTm51S3m2b4TvfIlkcXS7IHHzd4F6 MnfsO|IhcA>? NWPyZo1CUUN3MDC9JFAvQTNizszN NETwe489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEK4NVk2Oid-MUiyPFE6PTJ:L3G+
HL60 NHW1RYFEgXSxdH;4bYNqfHliYYPzZZk> MmrEO|IhcA>? NUPJcJVxUUN3MDC9JFAvQTNizszN Mkf5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{OEG5OVIoRjF6MkixPVUzRC:jPh?=
Bel7402 M334dGN6fG:2b4jpZ4l1gSCjc4PhfS=> M3LDUVI1KGh? MnrqTWM2OCB;IECuPVMh|ryP NYPDS4NRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiyPFE6PTJpPkG4NlgyQTV{PD;hQi=>
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KBV20C NGTTR2REgXSxdH;4bYNqfHliYYPzZZk> MmT3OFghcA>? NIPHXXpKSzVyIE2gNU41PCEQvF2= Ml;OQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{OUW0PVAoRjF6Mkm1OFkxRC:jPh?=
DU145 Mmj1R5l1d3SxeHnjbZR6KGG|c3H5 M3i3TVczKGh? M4\PRWlEPTBiPTCwMlAxPSEQvF2= Ml;VQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MEi1OlYoRjF6M{C4OVY3RC:jPh?=
HL60 NIfremJEgXSxdH;4bYNqfHliYYPzZZk> NHvlb3o4OiCq NET6NGZKSzVyIE2gNE4xODVizszN M2PhdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{C4OVY3Lz5zOEOwPFU3PjxxYU6=
MDA435 M{K2UGN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml7TO|IhcA>? MWrJR|UxKD1iMD6wNFUh|ryP Mn3DQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MEi1OlYoRjF6M{C4OVY3RC:jPh?=
MESSA NEXvfWlEgXSxdH;4bYNqfHliYYPzZZk> MXi3NkBp M3HofWlEPTBiPTCwMlAxPSEQvF2= NFyxZ3o9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
P388 MYrDfZRwfG:6aXPpeJkh[XO|YYm= M2rLWVczKGh? NX\tT3BwUUN3MDC9JFAvODFizszN NH7hNpQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
HL60/TX1000 M2nlOWN6fG:2b4jpZ4l1gSCjc4PhfS=> M33IXVczKGh? MkfuTWM2OCB;IEWg{txO Mnv0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MEi1OlYoRjF6M{C4OVY3RC:jPh?=
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K562 NGfjSVlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHHPclA4OiCq NF\YWpVKSzVyIE2gNE4xODB4IN88US=> NV76UVBIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNVM{ODdpPkG4N|E{OzB5PD;hQi=>
KB3-1 NGDsTXJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVy3NkBp M1X3[2lEPTBiPTCwMlAxOiEQvF2= M3jHR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{GzN|A4Lz5zOEOxN|MxPzxxYU6=
HepG2 MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NX71OJFrPzJiaB?= Mm\nTWM2OCB;IECuNFA4KM7:TR?= NHjoVIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOxN|MxPyd-MUizNVM{ODd:L3G+
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HepG2 Mk[5R5l1d3SxeHnjbZR6KGG|c3H5 MmryN{Bl[Xm| NEOxUJlKSzVyIE2gNE4xPDZ6IN88US=> M3jNUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
MDA-MB-231 M4ezRmN6fG:2b4jpZ4l1gSCjc4PhfS=> NXjadW9DOyCmYYnz M2LjPWlEPTBiPTCwMlA4ODNizszN MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDRzOUG1OEc,OTh2MUmxOVQ9N2F-
Hep3B M{XuV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NFPjcIY{KGSjeYO= M2rucWlEPTBiPTCwMlE{KM7:TR?= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDRzOUG1OEc,OTh2MUmxOVQ9N2F-
CCRF-CEM NFfyd4NEgXSxdH;4bYNqfHliYYPzZZk> NUnKXXJJPzJiaB?= NVXhdGxpUUN3MDC9JFAvODBzMke0JO69VQ>? Ml;uQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh2NUC0OVYoRjF6NEWwOFU3RC:jPh?=
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HepG2 NVPxXHBXSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NGjweIE1QCCq NX3uPHY4UUN3MDC9JFAvPjJizszN NF;3d2M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEewNVMxOSd-MUi3NFE{ODF:L3G+
PC3 MWXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MnnTOFghcA>? MU\JR|UxKD1iMj63N{DPxE1? M3;w[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{CxN|AyLz5zOEewNVMxOTxxYU6=
HCT116 NXn1Ro9KSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MmfhOFghcA>? NGnmOHlKSzVyIE2gOk4yQCEQvF2= NXTNeFlURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFE{ODFpPkG4O|AyOzBzPD;hQi=>
A549 MnfYR5l1d3SxeHnjbZR6KGG|c3H5 MUfJR|UxKD1iMD6wNFIh|ryP MonnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5MUW3PFIoRjF6N{G1O|gzRC:jPh?=
CCRF-CEM MX\DfZRwfG:6aXPpeJkh[XO|YYm= Mn\xO|IhcA>? NWnEVZM{UUN3MDC9JFAvODBzMTFOwG0> M3XBcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{WyPFY6Lz5zOEe1Nlg3QTxxYU6=
SKOV3 MkPmRY51cWOjbnPldkBie3OjeR?= MoS3O|IhcA>? MmTSTWM2OCB;IECuNFAyOzRizszN MlvlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh5NkKzOVgoRjF6N{[yN|U5RC:jPh?=
MCF7 NUPlSXJoS3m2b4TvfIlkcXS7IHHzd4F6 M3SxW2VFPTBiPTCwMlAxOzJizszN NELGeY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEmyOlcxOSd-MUi5NlY4ODF:L3G+
NCI/ADR-RES NV;SO|F1S3m2b4TvfIlkcXS7IHHzd4F6 NHT1SVVGTDVyIE2gNU42KM7:TR?= M1PVWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUK2O|AyLz5zOEmyOlcxOTxxYU6=
PANC1 MnHWR5l1d3SxeHnjbZR6KGG|c3H5 NV7PbIxRPzJiaB?= MX7JR|UxKD1iMD6wNFk6KM7:TR?= NFfJUnQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm1NVc5Pyd-MUi5OVE4QDd:L3G+
DLD1 NX3wemhoS3m2b4TvfIlkcXS7IHHzd4F6 MVO3NkBp M2P0XGlEPTBiPTCwMlAzOiEQvF2= NWGxXINORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5OVE4QDdpPkG4PVUyPzh5PD;hQi=>
AsPC1 Mk\jR5l1d3SxeHnjbZR6KGG|c3H5 NEfpPIk4OiCq M3vsW2lEPTBiPTCwMlA5QSEQvF2= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl3MUe4O{c,OTh7NUG3PFc9N2F-
NCI/ADR-RES NIi3fndEgXSxdH;4bYNqfHliYYPzZZk> M4HKWFczKGh? NILTfFhKSzVyIE2gNU4{KM7:TR?= MnTIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7NUG3PFcoRjF6OUWxO|g4RC:jPh?=
MCF7 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MVzFSFUxKD1iMD6wNFIyKM7:TR?= MmG0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7N{e2OVkoRjF6OUe3OlU6RC:jPh?=
NCI/ADR-RES NUPUfpV{S3m2b4TvfIlkcXS7IHHzd4F6 NIHqeWdGTDVyIE2gNkDPxE1? NF7VUVY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm3O|Y2QSd-MUi5O|c3PTl:L3G+
A431 NXjSeldwS3m2b4TvfIlkcXS7IHHzd4F6 MUO3NkBp MWnJR|UxKD1iMD6wNlUyKM7:TR?= MlLvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh7OUC1O|QoRjF6OUmwOVc1RC:jPh?=
MCF7 Mom1R5l1d3SxeHnjbZR6KGG|c3H5 NGi5TWw4OiCq MXfJR|UxKD1iMD6wN|kh|ryP NXnCd|lyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5PVA2PzRpPkG4PVkxPTd2PD;hQi=>
MDA-MB-231 NYjkbIF4S3m2b4TvfIlkcXS7IHHzd4F6 MknZO|IhcA>? NIfoPY5KSzVyIE2gNE4xPDdzIN88US=> MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl7MEW3OEc,OTh7OUC1O|Q9N2F-
SKOV3 MnHRR5l1d3SxeHnjbZR6KGG|c3H5 M2XPOlczKGh? MkLZTWM2OCB;IECuNFY2QCEQvF2= NXrKSYN6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5PVA2PzRpPkG4PVkxPTd2PD;hQi=>
PANC1 NHPNXGZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFrrOo44OiCq NYLRdo1XUUN3MDC9JFAvODB7OTFOwG0> NVrTXm16RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNlI3PzlpPkG5NFIzPjd7PD;hQi=>
DLD1 MlnuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXf0dnU3PzJiaB?= MmDETWM2OCB;IECuNFIzKM7:TR?= MnKyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMkK2O|koRjF7MEKyOlc6RC:jPh?=
AsPC1 NHfQVZJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NHHXPZI4OiCq NVjxU5FXUUN3MDC9JFAvODh7IN88US=> NFfZRXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUCyNlY4QSd-MUmwNlI3Pzl:L3G+
NCI/ADR MkLrS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M4DKRVczKGh? M1;UPWlEPTBiPTCxMlMh|ryP NWPTbmpNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNlI3PzlpPkG5NFIzPjd7PD;hQi=>
A2780 NVvMd5dUSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MnTXNkBl[Xm| MULJR|UxKD1iMD6wNlM1KM7:TR?= NXPzWG9{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwNlgyODJpPkG5NFI5OTB{PD;hQi=>
KB MUjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NYfq[4ZWOyCmYYnz NGPIeFJKSzVyIE2gNE4xODJ3IN88US=> NIHZbmk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC0NVI1Pyd-MUmwOFEzPDd:L3G+
COLO205 NW\jSYV3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NHvBVFAzPCCq MmewTWM2OCB;IECuNFA{OyEQvF2= NIe2c489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC0NVI1Pyd-MUmwOFEzPDd:L3G+
KB 8.5 NGfXT4RCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MmLrN{Bl[Xm| NW\hV3pJUUN3MDC9JFAvODJ4IN88US=> M1TyeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MESxNlQ4Lz5zOUC0NVI1PzxxYU6=
KBV1 MnLYRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Mnn2N{Bl[Xm| M3Ltc2lEPTBiPTCyMlAyOyEQvF2= NVjYOGpkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOFEzPDdpPkG5NFQyOjR5PD;hQi=>
KB NF3xZotIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1XGc|czKGh? MkLCTWM2OCB;IECuNFA{OyEQvF2= NVvDdm5ERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4PzNpPkG5NFU{Pzd|PD;hQi=>
KB-7D NUGwVlRLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYm3NkBp MVzJR|UxKD1iMD6wNFc6KM7:TR?= MknZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3O|MoRjF7MEWzO|c{RC:jPh?=
Pgp170 overexpressing multidrug resistant-KB-TAX50 MkX6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXW3NkBp MmfxTWM2OCB;IECuNlc{KM7:TR?= M33oRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|c{Lz5zOUC1N|c4OzxxYU6=
NPC-TW01 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NUXafnpDPzJiaB?= MV\JR|UxKD1iMD6wNFYh|ryP M3fR[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|gyLz5zOUC1N|c5OTxxYU6=
MES-SA MX;DfZRwfG:6aXPpeJkh[XO|YYm= NHPK[nE4OiCq NWLKXlJjUUN3MDC9JFAvODB6IN88US=> M1rjWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|gyLz5zOUC1N|c5OTxxYU6=
NCI-H838 MmLPR5l1d3SxeHnjbZR6KGG|c3H5 MU[3NkBp MYLJR|UxKD1iMD6wNlYh|ryP MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
HCT116 NXH3OIt6S3m2b4TvfIlkcXS7IHHzd4F6 MX[3NkBp M2T6VmlEPTBiPTCwMlA3OSEQvF2= NVXq[HBzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4QDFpPkG5NFU{PzhzPD;hQi=>
cells after 72 hrs by MTT assay NVLp[WJTS3m2b4TvfIlkcXS7IHHzd4F6 Ml;TTWM2OCB;IEWuNVQh|ryP MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB3M{e4NUc,OTlyNUO3PFE9N2F-
Hep3B MlvoR5l1d3SxeHnjbZR6KGG|c3H5 NUXMR5N2PzJiaB?= NXr5TVMzUUN3MDC9JFcvOjZizszN NHW0S4c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c5OSd-MUmwOVM4QDF:L3G+
A498 NWeyWVB{S3m2b4TvfIlkcXS7IHHzd4F6 NXi1SHVwPzJiaB?= MULJR|UxKD1iOD64NUDPxE1? NWXBbG1qRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4QDFpPkG5NFU{PzhzPD;hQi=>
NB4 M{SxXmN6fG:2b4jpZ4l1gSCjc4PhfS=> NXvOcI42PDhiaB?= NFrXephKSzVyIE2gNE4yKM7:TR?= NIK0cW49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
A549 NFrnUmNEgXSxdH;4bYNqfHliYYPzZZk> M1;y[|Q5KGh? M3TwdWlEPTBiPTCwMlEh|ryP MkPJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyN{KyNFkoRjF7MEeyNlA6RC:jPh?=
MCF7 NIW4RlFEgXSxdH;4bYNqfHliYYPzZZk> MXq0PEBp NFq0VGhKSzVyIE2gNE4yKM7:TR?= M1fBeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEeyNlA6Lz5zOUC3NlIxQTxxYU6=
SH-SY5Y Mkf1R5l1d3SxeHnjbZR6KGG|c3H5 M1K3dFQ5KGh? NV;nW2VyUUN3MDC9JFAvOiEQvF2= NFfRb|Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
PC3 NXTYSpFjS3m2b4TvfIlkcXS7IHHzd4F6 NHfJTWI1QCCq NGH1OWdKSzVyIE2gNE4zKM7:TR?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB5MkKwPUc,OTlyN{KyNFk9N2F-
DLD1 M1y3d2N6fG:2b4jpZ4l1gSCjc4PhfS=> NX\BU2k1PzJiaB?= MoXHS2k2OCB;IECuNFEh|ryP NH\DNmo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC4NVI1QSd-MUmwPFEzPDl:L3G+
B16 M4\XSmN6fG:2b4jpZ4l1gSCjc4PhfS=> MYW3NkBp NGLHRolIUTVyIE2gNE4xOSEQvF2= M{i5eVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
A172 M4LxW2N6fG:2b4jpZ4l1gSCjc4PhfS=> MlL2O|IhcA>? MlP5S2k2OCB;IECuNFEh|ryP NYjXSnhGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPFEzPDlpPkG5NFgyOjR7PD;hQi=>
HeLa NYOwNYJiS3m2b4TvfIlkcXS7IHHzd4F6 NYn2fXNkPzJiaB?= MlK4S2k2OCB;IECuNFIh|ryP M2T5cVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
U87 NYDrOI43S3m2b4TvfIlkcXS7IHHzd4F6 MkXVO|IhcA>? NGjYbo9IUTVyIE2gNE4xOiEQvF2= NUewTot1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPFEzPDlpPkG5NFgyOjR7PD;hQi=>
SiHa M4nSb2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoTRO|IhcA>? NXzPcHVKT0l3MDC9JFAvODNizszN M1viRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
HeLa MYrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NUTlPYRUQTZiaB?= NIn3bmlKSzVyIE2gNE4xODFizszN MmjOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOUG1O|koRjF7MEmxOVc6RC:jPh?=
SKOV3 NV3tc4cySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MlPVPVYhcA>? MnvLTWM2OCB;IECuNFE3KM7:TR?= NH;Vdpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC5NVU4QSd-MUmwPVE2Pzl:L3G+
BGC823 MnLyRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NU\GV3pQQTZiaB?= MnnZTWM2OCB;IECuNFE5QSEQvF2= NFPDNVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC5NVU4QSd-MUmwPVE2Pzl:L3G+
HCT116 NH;IO|JEgXSxdH;4bYNqfHliYYPzZZk> NWnBd4EyPzJiaB?= M33acWlEPTBiPTCwMlAxOTFizszN MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{NEK1NEc,OTlzMkSyOVA9N2F-
CCRF-CEM MmXJR5l1d3SxeHnjbZR6KGG|c3H5 NWLSV485PzJiaB?= MkDlTWM2OCB;IECuNFA{OSEQvF2= M2XlNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MUK0NlUxLz5zOUGyOFI2ODxxYU6=
MX1 MlW3R5l1d3SxeHnjbZR6KGG|c3H5 MV[3NkBp NGTwNXhKSzVyIE2gNE4xPDZizszN MmPNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlzMkSyOVAoRjF7MUK0NlUxRC:jPh?=
HCT116 M4\0[GN6fG:2b4jpZ4l1gSCjc4PhfS=> NVTjN4tHPCCmYYnz MmD6TWM2OCB;IECuNFAyOSEQvF2= NIS5TZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyPFE2Pid-MUmxNlgyPTZ:L3G+
HT-29 NVzMTJhVS3m2b4TvfIlkcXS7IHHzd4F6 NHLUcoI1KGSjeYO= MlnRTWM2OCB;IECuNFA{PiEQvF2= NEfEZYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyPFE2Pid-MUmxNlgyPTZ:L3G+
A2780 MorrR5l1d3SxeHnjbZR6KGG|c3H5 MVG0PEBp MUDJR|UxKD1iMD6wNFE{KM7:TR?= NGXjVVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyPFk4Oid-MUmxNlg6PzJ:L3G+
KB NVHPOVNnT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH7VNYdGTDVyIE2gNE4xOjNizszN NXXW[og6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmxOlE{OTZpPkG5NVYyOzF4PD;hQi=>
HepG2 NH3OXGtEgXSxdH;4bYNqfHliYYPzZZk> M3Xlc2dKPTBiPTCwMlAxOSEQvF2= M{PKb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MUm1PVAyLz5zOUG5OVkxOTxxYU6=
WI38 MVrDfZRwfG:6aXPpeJkh[XO|YYm= M3jTTmdKPTBiPTCwMlAyOzdizszN NIXCPVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUG5OVkxOSd-MUmxPVU6ODF:L3G+
RKO NGHlcWxCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3vPSmlEPTBiPTCwMlAzKM7:TR?= NInQdY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKyNFAyQCd-MUmyNlAxOTh:L3G+
KB/HeLa M1P4RmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NUnCcGt4UUN3MDC9JFAvODNizszN MmD6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{MkCwNVgoRjF7MkKwNFE5RC:jPh?=
SKOV3 MXrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NYHsNHFMUUN3MDC9JFAvODVizszN MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
SF268 M{PwcGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M{fnSGlEPTBiPTCwMlA2KM7:TR?= NVfwe3d5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyNlAxOThpPkG5NlIxODF6PD;hQi=>
P388 NXWxclAySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWDSNpQzPDhiaB?= MYrJR|UxKD1iMD6wOUDPxE1? MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
cells ectopic expression of human NXSxUY1GSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYG0PEBp MkHnTWM2OCB;IECuNFUh|ryP M4C0OFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkKwNFE5Lz5zOUKyNFAyQDxxYU6=
L1210 NVTDc5BySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NEjSSFk1QCCq NWnSbYhsUUN3MDC9JFAvODZizszN MmTVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{MkCwNVgoRjF7MkKwNFE5RC:jPh?=
NCI-H460 NXns[ItUSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYjJR|UxKD1iMD6wO{DPxE1? NW\Pbmw6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyNlAxOThpPkG5NlIxODF6PD;hQi=>
M2XORWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NHTTfGg1QCCq NXTwcGpCUUN3MDC9JFAvOyEQvF2= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
MCF7 M4jBXGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUfLUGU6PzJiaB?= NECyPFJKSzVyIE2gNE4xODF{IN88US=> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
A2780 NYfkOGdDS3m2b4TvfIlkcXS7IHHzd4F6 NHu0O2M4OiCq NFHJXJJKSzVyIE2gNE4xODF|ODFOwG0> MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
wild type A2780 M2fCOWN6fG:2b4jpZ4l1gSCjc4PhfS=> M4TJXFczKGh? NYDmXm16UUN3MDC9JFAvODBzNzFOwG0> NGnSU489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
cisplatin-resistant A2780 MVnDfZRwfG:6aXPpeJkh[XO|YYm= MlHXO|IhcA>? NYLp[G03UUN3MDC9JFAvODB{MjFOwG0> Mkj3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
LCC-6 MneyR5l1d3SxeHnjbZR6KGG|c3H5 NVjPNmNDPzJiaB?= M13QZ2lEPTBiPTCwMlAxOjR3IN88US=> M{flUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlQxLz5zOUKzPVI1ODxxYU6=
HT-29 MVHDfZRwfG:6aXPpeJkh[XO|YYm= MVO3NkBp M1vEe2lEPTBiPTCwMlAxOzZizszN Mnu3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
H460 NGPOUVhEgXSxdH;4bYNqfHliYYPzZZk> MmTVO|IhcA>? NFzsbXNKSzVyIE2gNE4xODR7IN88US=> NWjyWWoyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
topotecan-resistant A2780 MkSyR5l1d3SxeHnjbZR6KGG|c3H5 MWS3NkBp NWHDb2lPUUN3MDC9JFAvODB5MjFOwG0> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
PANC1 NUHtWmpxS3m2b4TvfIlkcXS7IHHzd4F6 NYDkd4V1PzJiaB?= MVrJR|UxKD1iMD6wNlU4KM7:TR?= MnrZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
1A9PTX22 NWHSbm5JS3m2b4TvfIlkcXS7IHHzd4F6 MV23NkBp M4[z[GlEPTBiPTCwMlE3ODdizszN MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
NCI/ADR MoSwR5l1d3SxeHnjbZR6KGG|c3H5 M3v1ZVczKGh? NXjQRpFoUUN3MDC9JFAvOyEQvF2= NF3EVos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
A2780 NGjEdHhHfW6ldHnvckBie3OjeR?= MnqzTWM2OCB;IECuN|g3KM7:TR?= NVrsOpFNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
1A9PTX10 M3f0[mN6fG:2b4jpZ4l1gSCjc4PhfS=> NGXkU4U4OiCq MXXJR|UxKD1iMD61N|I6PSEQvF2= NWjEeVJ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
A2780/ADR MorGR5l1d3SxeHnjbZR6KGG|c3H5 MnPhO|IhcA>? NUTEfVhnUUN3MDC9JFEvOjN7IN88US=> MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
A549 NXTpZlRYS3m2b4TvfIlkcXS7IHHzd4F6 M3PyV|I1KGh? M{W1WmlEPTBiPTCwMlAxPTJizszN M4L4eFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkS1NlYyLz5zOUK0OVI3OTxxYU6=
PC3M M1u0TmN6fG:2b4jpZ4l1gSCjc4PhfS=> NGHncXIzPCCq MkXQTWM2OCB;IECuNFI4KM7:TR?= NX\XbJdFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOFUzPjFpPkG5NlQ2OjZzPD;hQi=>
HCT8 MlHWR5l1d3SxeHnjbZR6KGG|c3H5 MnfKNlQhcA>? MkjMTWM2OCB;IECuNFM4KM7:TR?= Mof0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{NEWyOlEoRjF7MkS1NlYyRC:jPh?=
Bel7402 M4jyXWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYXROm9OOjRiaB?= MWLJR|UxKD1iMD6wPVUh|ryP NYq4cJFGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOFUzPjFpPkG5NlQ2OjZzPD;hQi=>
A2780 MWfDfZRwfG:6aXPpeJkh[XO|YYm= MVPJR|UxKD1iMD6wNVQh|ryP MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ6MkG4Okc,OTl{OEKxPFY9N2F-
SNU398 MY\BdI9xfG:|aYOgZZN{[Xl? NG\nWXM1QCCq MlHtS2k2OCB;IECuNFEh|ryP NWL0bHh[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyPFIyQDhpPkG5NlgzOTh6PD;hQi=>
HCT116 NYXZSmVUSXCxcITvd4l{KGG|c3H5 MWi0PEBp M{C5VGVEPTBiPTCwMlAzOyEQvF2= M1zPc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkiyNVg5Lz5zOUK4NlE5QDxxYU6=
T47D Mlz1RZBweHSxc3nzJIF{e2G7 MY[0PEBp MWLFR|UxKD1iMD6wN|Uh|ryP NYDoT4lJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyPFIyQDhpPkG5NlgzOTh6PD;hQi=>
PC3 NELMeVNEgXSxdH;4bYNqfHliYYPzZZk> NX;zPGpYPCCmYYnz Moe0TWM2OCB;IECuNFAyPCEQvF2= M3u2OVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{W5NVY6Lz5zOUO1PVE3QTxxYU6=
A2780 M3vzdmN6fG:2b4jpZ4l1gSCjc4PhfS=> NX;sZ41uPCCmYYnz M4LDTGlEPTBiPTCwMlAyPDlizszN NX;VXHNqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmzOVkyPjlpPkG5N|U6OTZ7PD;hQi=>
K562 NUXIc4czS3m2b4TvfIlkcXS7IHHzd4F6 NF;qc5k1QCCq MnzPTWM2OCB;IEGuNVYh|ryP MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN3OUG4OUc,OTl|NUmxPFU9N2F-
MCF7 MlrXR5l1d3SxeHnjbZR6KGG|c3H5 MlTtOFghcA>? NF\pempKSzVyIE2gNk4yOSEQvF2= MmLXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|NUmxPFUoRjF7M{W5NVg2RC:jPh?=
A549 MljHR5l1d3SxeHnjbZR6KGG|c3H5 NH;RfYw1QCCq MW\JR|UxKD1iMj60OkDPxE1? M{HnTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{W5NVg2Lz5zOUO1PVE5PTxxYU6=
SGC M1vUdmN6fG:2b4jpZ4l1gSCjc4PhfS=> NX3MVGtLPDhiaB?= MWTJR|UxKD1iMz6zOEDPxE1? M3uzblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{W5NVg2Lz5zOUO1PVE5PTxxYU6=
HCT116 NEHqZYZEgXSxdH;4bYNqfHliYYPzZZk> NWnve3h1PDhiaB?= M3T2SmlEPTBiPTC0MlM4KM7:TR?= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN3OUG4OUc,OTl|NUmxPFU9N2F-
A431 NGD2eJBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3Oy[2dKPTBiPTCwMlAxODBzIN88US=> MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN7NEKxPEc,OTl|OUSyNVg9N2F-
MESSA NUOxWYhMSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MV\HTVUxKD1iMD6wNFAxOSEQvF2= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN7NEKxPEc,OTl|OUSyNVg9N2F-
HCT15 NX3hTGIzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M2i3WGdKPTBiPTCwMlAyOSEQvF2= M4\pXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{m0NlE5Lz5zOUO5OFIyQDxxYU6=
MES-SA/Dx5 NE[4XYRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MlXBS2k2OCB;IECuNVYh|ryP MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN7NEKxPEc,OTl|OUSyNVg9N2F-
HCT15/CLO2 M3f6WmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MnnOS2k2OCB;IECuPFMh|ryP MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN7NEKxPEc,OTl|OUSyNVg9N2F-
wild type A2780 MV\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MYq3NkBp NUHhXYx2UUN3MDC9JFAvODBzNzFOwG0> NYX3VpVpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlM{PDBpPkG5OFI{OzRyPD;hQi=>
cisplatin-resistant A2780 NVv2cXhzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NVe1fmdZPzJiaB?= M1PHTWlEPTBiPTCwMlAxOjJizszN MkflQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2MkOzOFAoRjF7NEKzN|QxRC:jPh?=
topotecan-resistant A2780 MUDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlXFO|IhcA>? MnPmTWM2OCB;IECuNFA4OiEQvF2= NVf3b2hFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlM{PDBpPkG5OFI{OzRyPD;hQi=>
adriamycin and doxorubicin-resistant A2780 M2HmcWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVnpN203PzJiaB?= M1TjT2lEPTBiPTCxMlI{QSEQvF2= NV;TNVE3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlM{PDBpPkG5OFI{OzRyPD;hQi=>
paclitaxel-resistant A2780TC1 NVX3RnlxTnWwY4Tpc44h[XO|YYm= NGDoSG9KSzVyIE2gOU45QThizszN M3Tk[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEKzN|QxLz5zOUSyN|M1ODxxYU6=
NB4 MoHpR5l1d3SxeHnjbZR6KGG|c3H5 MV:0PEBp Mmq0TWM2OCB;IECuNUDPxE1? M3PiflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK1OVg6Lz5zOUSyOVU5QTxxYU6=
A549 M2\OVWN6fG:2b4jpZ4l1gSCjc4PhfS=> NUi0doRLPDhiaB?= M3KxNGlEPTBiPTCwMlEh|ryP MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR{NUW4PUc,OTl2MkW1PFk9N2F-
MCF7 M2fLbGN6fG:2b4jpZ4l1gSCjc4PhfS=> NEDhZ3I1QCCq NYDqWJo2UUN3MDC9JFAvOSEQvF2= M4K0[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK1OVg6Lz5zOUSyOVU5QTxxYU6=
SH-SY5Y NVfTVllwS3m2b4TvfIlkcXS7IHHzd4F6 MVq0PEBp NXrEXnllUUN3MDC9JFAvOiEQvF2= NYjXVJRTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlU2QDlpPkG5OFI2PTh7PD;hQi=>
PC3 NUP3VlhvS3m2b4TvfIlkcXS7IHHzd4F6 MX20PEBp NHj3SJpKSzVyIE2gNE4zKM7:TR?= M2XoblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK1OVg6Lz5zOUSyOVU5QTxxYU6=
SNU398 MYHBdI9xfG:|aYOgZZN{[Xl? NVXEZ4lDPDhiaB?= NWXsN4Y2TUN3MDC9JFAvODB7IN88US=> NY\Bb3M2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0Olc2QThpPkG5OFY4PTl6PD;hQi=>
HCT116 MVXBdI9xfG:|aYOgZZN{[Xl? NWnITYhGPDhiaB?= NWTNSZBJTUN3MDC9JFAvODF6IN88US=> Mm\4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2Nke1PVgoRjF7NE[3OVk5RC:jPh?=
T47D M2jCd2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYXr[3F7PDhiaB?= NF\TN5lIUTVyIE2gNE4xOjZizszN MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR4N{W5PEc,OTl2Nke1PVg9N2F-
MCF7 NYTtR4t[S3m2b4TvfIlkcXS7IHHzd4F6 Ml7FOFghcA>? MVnJR|UxKD1iMD6wPEDPxE1? MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTR4N{i3O{c,OTl2Nke4O|c9N2F-
HepG2 MYnDfZRwfG:6aXPpeJkh[XO|YYm= NEOxWFNIUTVyIE2gNE4xPTlizszN NVPkUWF5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0O|Y{OzZpPkG5OFc3OzN4PD;hQi=>
H1299 M1H0TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MkTKOFghcA>? NHzUdnpIUTVyIE2gNE4xOjNizszN MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTVyMEm3Okc,OTl3MEC5O|Y9N2F-
T47D Mkn0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXPTWlVbPDhiaB?= NVrLTJBwT0l3MDC9JFAvODJ4IN88US=> MkXiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl3MEC5O|YoRjF7NUCwPVc3RC:jPh?=
DLD1 NH[4WnRCeG:ydH;zbZMh[XO|YYm= MoHmOFghcA>? M3XHcmVEPTBiPTCwMlA2PCEQvF2= MlnvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl3MEC5O|YoRjF7NUCwPVc3RC:jPh?=
HCT116 NGXBcJBEgXSxdH;4bYNqfHliYYPzZZk> MlnWO|IhcA>? NHf3cWxKSzVyIE2gNE4xODFzIN88US=> NYrSTnNSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm1O|Y4QDVpPkG5OVc3Pzh3PD;hQi=>
CCRF-CEM NUPBZ21CS3m2b4TvfIlkcXS7IHHzd4F6 NESwTVg4OiCq M{\lPWlEPTBiPTCwMlAxOTJizszN MnvUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl3N{[3PFUoRjF7NUe2O|g2RC:jPh?=
MX1 NGHiSWpEgXSxdH;4bYNqfHliYYPzZZk> NGrTRYw4OiCq NWrhOnl4UUN3MDC9JFAvODR4IN88US=> MoDlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl3N{[3PFUoRjF7NUe2O|g2RC:jPh?=
vinblastine-resistant CCRF-CEM NHLo[5FEgXSxdH;4bYNqfHliYYPzZZk> NXH2RpJYPzJiaB?= MkHXTWM2OCB;IECuOEDPxE1? NVHV[lZRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm1O|Y4QDVpPkG5OVc3Pzh3PD;hQi=>
taxol-resistant CCRF-CEM M2HVXWN6fG:2b4jpZ4l1gSCjc4PhfS=> M4DXXVczKGh? NV;LS5Q3UUN3MDC9JFEvOiEQvF2= MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTV5Nke4OUc,OTl3N{[3PFU9N2F-
MCF7 NYK2V2hNT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXLSToJOPDhiaB?= MnSxTWM2OCB;IECuNFA{KM7:TR?= NGfGNmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOU[wNVU6PCd-MUm2NFE2QTR:L3G+
PtK2 NFvjfmhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NYrNfIxwUUN3MDC9JFAvODJzIN88US=> NVe4eo1sRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2NFE2QTRpPkG5OlAyPTl2PD;hQi=>
rat A10 MkDhS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MorwTWM2OCB;IECuNFM5KM7:TR?= MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTZyMUW5OEc,OTl4MEG1PVQ9N2F-
HCT116 MnTKRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M2HuZ|czKGh? MXnJR|UxKD1iMD6wNFA5KM7:TR?= NWPSO|lWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2OlU{QDRpPkG5OlY2Ozh2PD;hQi=>
PC3 M33zXWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MoT1O|IhcA>? MWHJR|UxKD1iMD6wNFA5KM7:TR?= M{HL[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7Nk[1N|g1Lz5zOU[2OVM5PDxxYU6=
NCI/ADR MYnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MVW3NkBp MnzxTWM2OCB;IECuNFA1KM7:TR?= NHTVZ2g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOU[2OVM5PCd-MUm2OlU{QDR:L3G+
HuH7 Mn;uRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NXHafm8xPzJiaB?= MXrJR|UxKD1iMD6wNFgh|ryP M4DhR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7Nk[1N|g1Lz5zOU[2OVM5PDxxYU6=
Caco-2 MUPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NUPJXGZLPzJiaB?= M3\4[mlEPTBiPTCwMlAzKM7:TR?= NVHyZ|NlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2OlU{QDRpPkG5OlY2Ozh2PD;hQi=>
MES-SA/Dx5 MkT1R5l1d3SxeHnjbZR6KGG|c3H5 NYOzdFNuUUN3MDC9JFcvPTN6IN88US=> NUXLS|ZIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm2O|k1PzVpPkG5Olc6PDd3PD;hQi=>
A549 M3fOcmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mm\XTWM2OCB;IECuNFAzOyEQvF2= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTdyOE[3PUc,OTl5MEi2O|k9N2F-
BGC823 MoTaR5l1d3SxeHnjbZR6KGG|c3H5 M4DDPWlEPTBiPTCwMlAxOzNizszN NWfJOGR6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3NFg3PzlpPkG5O|A5Pjd7PD;hQi=>
HCT8 NInpO4FEgXSxdH;4bYNqfHliYYPzZZk> NVH5TpRvUUN3MDC9JFAvODB|NjFOwG0> NVrTOmY1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3NFg3PzlpPkG5O|A5Pjd7PD;hQi=>
A2780 Mn\aR5l1d3SxeHnjbZR6KGG|c3H5 M4D5eWlEPTBiPTCwMlAxPzlizszN M1LRTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{C4Olc6Lz5zOUewPFY4QTxxYU6=
Bel7404 MVrDfZRwfG:6aXPpeJkh[XO|YYm= NH\GUG5KSzVyIE2gNE4xOTJ|IN88US=> MlK3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5MEi2O|koRjF7N{C4Olc6RC:jPh?=
DG75 NVfKOYpiSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MnvUNlQhfG9iN{KgbC=> NUDwTI9qUUN3MDC9JFAvODFizszN NHLZ[nY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUexO|IyPSd-MUm3NVczOTV:L3G+
MUTU-I NVHYNYlkSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MUOyOEBp NEXEV4dKSzVyIE2gNE4xOSEQvF2= NU[3UGVnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3NVczOTVpPkG5O|E4OjF3PD;hQi=>
HCT116 MYfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M1q0UFczKGh? NWHqZllMUUN3MDC9JFAvODBzIN88US=> NIPDcoY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0N|g3Oyd-MUm3OFM5PjN:L3G+
SW48 Mm\uRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NHLjfnM4OiCq M{\Eb2lEPTBiPTCwMlAxOSEQvF2= M3:zNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{SzPFY{Lz5zOUe0N|g3OzxxYU6=
MES-SA MWnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NU\QXWVzPzJiaB?= MkjJTWM2OCB;IECuNFAyKM7:TR?= MlTTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
CEM MWTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MXy3NkBp MYPJR|UxKD1iMD6wNFIh|ryP Moq3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
SW480 NUWzcJpqSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MUm3NkBp NFroeXVKSzVyIE2gNE4xODJizszN MnPOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
MCF7 MnTuR5l1d3SxeHnjbZR6KGG|c3H5 NFrJV2c4OiCq MUTJR|UxKD1iMD6wNFMh|ryP MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2M{i2N{c,OTl5NEO4OlM9N2F-
RL MXvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M2HsblczKGh? NUTzPI1NUUN3MDC9JFAvODB|IN88US=> NVHPTFdyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFM5PjNpPkG5O|Q{QDZ|PD;hQi=>
T47D NHXRelVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NWe4VoRLPzJiaB?= NYTaPW1WUUN3MDC9JFAvODB2IN88US=> NIrKSY49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0N|g3Oyd-MUm3OFM5PjN:L3G+
UACC-812 M3zyVWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M1;LUVczKGh? NGnpfHdKSzVyIE2gNE44KM7:TR?= NEL0RYM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe0N|g3Oyd-MUm3OFM5PjN:L3G+
DU145 NET5RYZEgXSxdH;4bYNqfHliYYPzZZk> MU[3NkBp MoT3TWM2OCB;IESuPFQh|ryP NHrQcmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe1OFE{OCd-MUm3OVQyOzB:L3G+
LNCAP NFTHNXVEgXSxdH;4bYNqfHliYYPzZZk> MoLBO|IhcA>? MnvDTWM2OCB;IE[uN|Ih|ryP NEP0Xpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUe1OFE{OCd-MUm3OVQyOzB:L3G+
HT-29 MlWwR5l1d3SxeHnjbZR6KGG|c3H5 MV[xJIg> MVnJR|UxKD1iMD6wNFM1KM7:TR?= MnPPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5N{iwOlcoRjF7N{e4NFY4RC:jPh?=
HCT116 NXX0ZYpoS3m2b4TvfIlkcXS7IHHzd4F6 M37XbVEhcA>? NHi3[JFKSzVyIE2gNE4xODN3IN88US=> NVK2SpdORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3O|gxPjdpPkG5O|c5ODZ5PD;hQi=>
K562 NWTIbIQ2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NGD0Nnk1QCCq MmrwTWM2OCB;IEGuNVYh|ryP NVfpPHZURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm4NVU{OTZpPkG5PFE2OzF4PD;hQi=>
A549 NIHtbnhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= Mnf0OFghcA>? M131WGlEPTBiPTCyMlI5KM7:TR?= M{\oblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7OEG1N|E3Lz5zOUixOVMyPjxxYU6=
SGC7901 MWfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MmHCOFghcA>? MXHJR|UxKD1iMz6zOEDPxE1? NXH5[Go{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm4NVU{OTZpPkG5PFE2OzF4PD;hQi=>
HCT116 Mlm4RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MoD0OFghcA>? MmPrTWM2OCB;IESuN|ch|ryP MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQThzNUOxOkc,OTl6MUWzNVY9N2F-
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HCT8 NHfUTVBEgXSxdH;4bYNqfHliYYPzZZk> NVvzO2h5QTZiaB?= MlXrTWM2OCB;IEOuOkDPxE1? MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODV4ME[0O{c,OjB3NkC2OFc9N2F-
Bel7402 NHeyOItEgXSxdH;4bYNqfHliYYPzZZk> Mo[5PVYhcA>? MYfJR|UxKD1iNj6zJO69VQ>? MnvXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB3NkC2OFcoRjJyNU[wOlQ4RC:jPh?=
A2780 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MVGzJIRigXN? MX3JR|UxKD1iMD62OUDPxE1? MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODV7M{izPUc,OjB3OUO4N|k9N2F-
HCT8 NWHEU|h3S3m2b4TvfIlkcXS7IHHzd4F6 MlP1N{Bl[Xm| NFH6O2RKSzVyIE2gNE43PyEQvF2= MljYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB3OUO4N|koRjJyNUmzPFM6RC:jPh?=
Bel7402 MoeyR5l1d3SxeHnjbZR6KGG|c3H5 MVezJIRigXN? NUPXeYNoUUN3MDC9JFEvQCEQvF2= NHL4Zmk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEW5N|g{QSd-MkC1PVM5Ozl:L3G+
KB MUjDfZRwfG:6aXPpeJkh[XO|YYm= Mn7KTWM2OCB;IECuNFgh|ryP M4HiNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNkK3O|IyLz5{ME[yO|czOTxxYU6=
786-0 M3HtT2N6fG:2b4jpZ4l1gSCjc4PhfS=> NUS5d|FKUUN3MDC9JFAvODhizszN M3\BRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNkK3O|IyLz5{ME[yO|czOTxxYU6=
HepG2 MV3DfZRwfG:6aXPpeJkh[XO|YYm= MXPJR|UxKD1iMD6wPEDPxE1? MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODZ{N{eyNUc,OjB4Mke3NlE9N2F-
OS-RC2 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MVrJR|UxKD1iMD6wPEDPxE1? NGfR[GM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{ME[yO|czOSd-MkC2Nlc4OjF:L3G+
22Rv1 NImyNGFEgXSxdH;4bYNqfHliYYPzZZk> NELpW3NKSzVyIE2gNE4xQCEQvF2= NYnZOZpLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC2Nlc4OjFpPkKwOlI4PzJzPD;hQi=>
HT-29 NG\XdVBEgXSxdH;4bYNqfHliYYPzZZk> NYT0N|A3UUN3MDC9JFAvOzhizszN MlrKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB4Mke3NlEoRjJyNkK3O|IyRC:jPh?=
A375 M4rkc2N6fG:2b4jpZ4l1gSCjc4PhfS=> NF6xeotKSzVyIE2gNE45OSEQvF2= NV7ENpY3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC2Nlc4OjFpPkKwOlI4PzJzPD;hQi=>
MCF7 MmTGR5l1d3SxeHnjbZR6KGG|c3H5 MmS4TWM2OCB;IEGuN{DPxE1? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODZ{N{eyNUc,OjB4Mke3NlE9N2F-
BCG823 Ml2wR5l1d3SxeHnjbZR6KGG|c3H5 Ml;PTWM2OCB;IEGuOUDPxE1? MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODZ{N{eyNUc,OjB4Mke3NlE9N2F-
769-P M1uzRWN6fG:2b4jpZ4l1gSCjc4PhfS=> MWnJR|UxKD1iNz6xJO69VQ>? Moq2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB4Mke3NlEoRjJyNkK3O|IyRC:jPh?=
KB Mm\nR5l1d3SxeHnjbZR6KGG|c3H5 M2jBZmlEPTBiPTCwMlA5KM7:TR?= NWH5RmZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3NVY1PjhpPkKwO|E3PDZ6PD;hQi=>
786-0 M3XlUGN6fG:2b4jpZ4l1gSCjc4PhfS=> M17MUmlEPTBiPTCwMlA5KM7:TR?= NUDjWXRmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3NVY1PjhpPkKwO|E3PDZ6PD;hQi=>
OS-RC2 M1XwWWN6fG:2b4jpZ4l1gSCjc4PhfS=> M1X6dmlEPTBiPTCwMlA5KM7:TR?= NWXJVFd1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3NVY1PjhpPkKwO|E3PDZ6PD;hQi=>
22Rv1 M4jWfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NFzPdGZKSzVyIE2gNE4xQCEQvF2= MkS2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5MU[0OlgoRjJyN{G2OFY5RC:jPh?=
HepG2 NV\seGZ5S3m2b4TvfIlkcXS7IHHzd4F6 MUfJR|UxKD1iMD6wPEDPxE1? MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODdzNkS2PEc,OjB5MU[0Olg9N2F-
HT-29 MXnDfZRwfG:6aXPpeJkh[XO|YYm= MnnjTWM2OCB;IECuN|gh|ryP M1L4T|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{G2OFY5Lz5{MEexOlQ3QDxxYU6=
A375 MmT1R5l1d3SxeHnjbZR6KGG|c3H5 NInj[oFKSzVyIE2gNE45OSEQvF2= NYnHOWR7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3NVY1PjhpPkKwO|E3PDZ6PD;hQi=>
MCF7 M2nPTWN6fG:2b4jpZ4l1gSCjc4PhfS=> MknKTWM2OCB;IEGuN{DPxE1? NGrrVZY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexOlQ3QCd-MkC3NVY1Pjh:L3G+
BGC823 NHX4PJBEgXSxdH;4bYNqfHliYYPzZZk> MoXJTWM2OCB;IEGuOUDPxE1? M4PVRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{G2OFY5Lz5{MEexOlQ3QDxxYU6=
769-P MojCR5l1d3SxeHnjbZR6KGG|c3H5 MY\JR|UxKD1iNz6xJO69VQ>? MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODdzNkS2PEc,OjB5MU[0Olg9N2F-
BGC823 NWK4UYpvS3m2b4TvfIlkcXS7IHHzd4F6 MlTnO|IhcA>? MV7JR|UxKD1iMD6wNFEh|ryP NVLCNlR{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3NVk2OTBpPkKwO|E6PTFyPD;hQi=>
A2780 Mo\qR5l1d3SxeHnjbZR6KGG|c3H5 NEjndHk4OiCq MmjHTWM2OCB;IECuNFAyKM7:TR?= MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODdzOUWxNEc,OjB5MUm1NVA9N2F-
A549 NGO1VlhEgXSxdH;4bYNqfHliYYPzZZk> NX\I[WttPzJiaB?= M4rqd2lEPTBiPTCwMlAyPiEQvF2= NH\kRXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexPVUyOCd-MkC3NVk2OTB:L3G+
HCT8 MnLtR5l1d3SxeHnjbZR6KGG|c3H5 M1TEUFczKGh? NFy1S5FKSzVyIE2gNE4xPTFizszN M32y[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{G5OVExLz5{MEexPVUyODxxYU6=
Bel7402 NEDmV45EgXSxdH;4bYNqfHliYYPzZZk> NWX0bI43PzJiaB?= MYfJR|UxKD1iMD6wOkDPxE1? NVrxUHBmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3NVk2OTBpPkKwO|E6PTFyPD;hQi=>
A549 NHyzWlJEgXSxdH;4bYNqfHliYYPzZZk> NFzHOXQ4OiCq M2rzNmlEPTBiPTCwMlAxOzhizszN M1fqRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{OyPFA6Lz5{MEezNlgxQTxxYU6=
HEK Mn33R5l1d3SxeHnjbZR6KGG|c3H5 M4myOlczKGh? NFPoe5NKSzVyIE2gNE4xODN7IN88US=> M{\wWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{OyPFA6Lz5{MEezNlgxQTxxYU6=
MCF7 NVHKfZRDS3m2b4TvfIlkcXS7IHHzd4F6 NXLFNIU2PzJiaB?= MWHJR|UxKD1iMD6wNFQ1KM7:TR?= NYLQVnd2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3N|I5ODlpPkKwO|MzQDB7PD;hQi=>
HeLa MlK1R5l1d3SxeHnjbZR6KGG|c3H5 NIGwSVQ4OiCq NX\hPXp[UUN3MDC9JFAvODB6OTFOwG0> M1TNT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{OyPFA6Lz5{MEezNlgxQTxxYU6=
Hep3B M3fwS2FvfGmlYX7j[ZIh[XO|YYm= NWfDOo9zOyCmYYnz NI\MXppIUTVyIE2gNE4xODB2IN88US=> MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODd|NUG0NEc,OjB5M{WxOFA9N2F-
DU145 MX3DfZRwfG:6aXPpeJkh[XO|YYm= NIDsfWVGTDVyIE2gNE4xODNizszN MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODd|OEGwN{c,OjB5M{ixNFM9N2F-
KB MVrDfZRwfG:6aXPpeJkh[XO|YYm= NEXrSmlGTDVyIE2gNE4xODdizszN MkS1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5M{ixNFMoRjJyN{O4NVA{RC:jPh?=
A549 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NIPjdGdGTDVyIE2gNE4xODhizszN NGTHT4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEezPFExOyd-MkC3N|gyODN:L3G+
MCF7 M4DIV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXSzbYNQPzJiaB?= NHy3VnJKSzVyIE2gNE4xODJizszN M2nkd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOECwOVAxLz5{MEiwNFUxODxxYU6=
wild type LCC-6 NIHKRYlEgXSxdH;4bYNqfHliYYPzZZk> NFX2XXY4OiCq MoTvTWM2OCB;IECuNFA{KM7:TR?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODhyMEWwNEc,OjB6MEC1NFA9N2F-
A2780 MkTWR5l1d3SxeHnjbZR6KGG|c3H5 MVm3NkBp NV:wUoJCUUN3MDC9JFAvODJizszN NVO4eopSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4NFA2ODBpPkKwPFAxPTByPD;hQi=>
CFPAC-1 MoTMR5l1d3SxeHnjbZR6KGG|c3H5 NGnxc4E4OiCq M3;5OWlEPTBiPTCwMlA1PyEQvF2= M3ewW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOECwOVAxLz5{MEiwNFUxODxxYU6=
multidrug-resistant LCC-6 NITXOHZEgXSxdH;4bYNqfHliYYPzZZk> NYXhUoE{PzJiaB?= MWLJR|UxKD1iMD6zO|kh|ryP MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODhyMEWwNEc,OjB6MEC1NFA9N2F-
NCI/ADR MYTDfZRwfG:6aXPpeJkh[XO|YYm= MkXsO|IhcA>? NFTPUpJKSzVyIE2gNE41OSEQvF2= MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODhyMEWwNEc,OjB6MEC1NFA9N2F-
multidrug-resistant MDA-MB-435/LCCMDR1 M3LwV2N6fG:2b4jpZ4l1gSCjc4PhfS=> MnnoOFghcA>? M{e5VGlEPTBiPTCwMlAxPCEQvF2= MoXPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB7MUm3NlAoRjJyOUG5O|IxRC:jPh?=
multidrug-resistant MDA-MB-435/LCCMDR1 NGjtV2xHfW6ldHnvckBie3OjeR?= MYLJR|UxKD1iMD6wOlk{KM7:TR?= M{\BRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUG5O|IxLz5{MEmxPVczODxxYU6=
MDA-MB-435 M1fNV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWf2Z2FtPDhiaB?= MYnJR|UxKD1iMD6yO|ch|ryP M{LsclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUG5O|IxLz5{MEmxPVczODxxYU6=
LNCAP NEjJUohEgXSxdH;4bYNqfHliYYPzZZk> M2WyPGlEPTBiPTCwMlAzOjNizszN M1yyS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUO2PFc1Lz5{MEmzOlg4PDxxYU6=
HT-29 M1vBb2N6fG:2b4jpZ4l1gSCjc4PhfS=> MWSzJIRigXN? Mkj1SWQ2OCB;IECuNFAxPiEQvF2= M1;Id|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUO5OVQxLz5{MEmzPVU1ODxxYU6=
HCT116 NI[2bI5Iem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1rQNVk3KGh? NWDwNGtJUUN3MDC9JFAvODB{IN88US=> MkfJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB7NEO0NFEoRjJyOUSzOFAyRC:jPh?=
HCT15 M2PlWmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnvBPVYhcA>? NVroWFlvUUN3MDC9JFAvOTRizszN MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODl2M{SwNUc,OjB7NEO0NFE9N2F-
HeLa M1jjWGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MmXCTWM2OCB;IECuNFAyPiEQvF2= MlXyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB7N{O0PFgoRjJyOUezOFg5RC:jPh?=
SKOV3 NVWzN5dySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M{LITWlEPTBiPTCwMlAxOyEQvF2= NVfrSXJlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC5O|M1QDhpPkKwPVc{PDh6PD;hQi=>
A549 NGL6WZBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHTHRo86PiCq NFfxbHdKSzVyIE2gNE4xODR7IN88US=> MofyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB7N{S1NFUoRjJyOUe0OVA2RC:jPh?=
MCF7 Mn[yRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NHnmO4E6PiCq NXu0c5F1UUN3MDC9JFAvODJzIN88US=> NEfXUJQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEm3OFUxPSd-MkC5O|Q2ODV:L3G+
HT-29 NEPWe|RCdnSrY3HuZ4VzKGG|c3H5 NX;xTVZJTUR3MDC9JFAvODByMTFOwG0> NVraU2NGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwOlczODZpPkKxNFY4OjB4PD;hQi=>
K562 M121OWN6fG:2b4jpZ4l1gSCjc4PhfS=> MV[0PEBp NUHYT5JJUUN3MDC9JFEvOTZizszN MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTB4N{mzN{c,OjFyNke5N|M9N2F-
MCF7 NXexUJJSS3m2b4TvfIlkcXS7IHHzd4F6 NED1SXc1QCCq NHn3b3RKSzVyIE2gNk4yOSEQvF2= NVvlXlY1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwOlc6OzNpPkKxNFY4QTN|PD;hQi=>
A549 NUDBPWNbS3m2b4TvfIlkcXS7IHHzd4F6 NGTjTmI1QCCq NEjmN2tKSzVyIE2gNk41PiEQvF2= NFr5eJU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC2O|k{Oyd-MkGwOlc6OzN:L3G+
SGC NYnmOYJ{S3m2b4TvfIlkcXS7IHHzd4F6 MVu0PEBp NGnNRpZKSzVyIE2gN{4{PCEQvF2= NXf1R5p1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwOlc6OzNpPkKxNFY4QTN|PD;hQi=>
HCT116 M1j3d2N6fG:2b4jpZ4l1gSCjc4PhfS=> MWS0PEBp MnT3TWM2OCB;IESuN|ch|ryP M1fpUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzME[3PVM{Lz5{MUC2O|k{OzxxYU6=
CCRF-CEM MnvNR5l1d3SxeHnjbZR6KGG|c3H5 M{L5ZlczKGh? MWfJR|UxKD1iMD6wNFMh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTFyNkO3O{c,OjFzME[zO|c9N2F-
MCF7 NW\DfmQxS3m2b4TvfIlkcXS7IHHzd4F6 MX[3NkBp NGD3SHNIUTVyIE2gNE4xODNizszN M1jSelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUG1NlExLz5{MUGxOVIyODxxYU6=
HT-29 MVXDfZRwfG:6aXPpeJkh[XO|YYm= MknpO|IhcA>? MUnHTVUxKD1iMD6wNFMh|ryP NHnUV4I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUGxOVIyOCd-MkGxNVUzOTB:L3G+
K562 NUDyfFIzS3m2b4TvfIlkcXS7IHHzd4F6 M4rJU|czKGh? M4PTcWdKPTBiPTCwMlAxPCEQvF2= M3m1XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUG1NlExLz5{MUGxOVIyODxxYU6=
PC3 M2q1[GN6fG:2b4jpZ4l1gSCjc4PhfS=> NHvtOHQ4OiCq M{TzdWdKPTBiPTCwMlAxPCEQvF2= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTFzNUKxNEc,OjFzMUWyNVA9N2F-
MCF7 NGm1[mJEgXSxdH;4bYNqfHliYYPzZZk> M4[1U|I1KGh? NY\ieXFPUUN3MDC9JFAvPjNizszN M4[2e|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUG1NlEzLz5{MUGxOVIyOjxxYU6=
SMMC7721 MVnDfZRwfG:6aXPpeJkh[XO|YYm= M1LCVFI1KGh? MYrJR|UxKD1iMT60NkDPxE1? MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTFzNUKxNkc,OjFzMUWyNVI9N2F-
A2780 NXXpZWd1S3m2b4TvfIlkcXS7IHHzd4F6 M3Xl[FQ5KHSxIEeyJIg> M2nVSmlEPTBiPTCwMlAyKM7:TR?= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTF{NkCyO{c,OjFzMk[wNlc9N2F-
Jurkat MXHD[YxtKGO7Y3zlJIFzemW|dDDhd5NigQ>? MYSyOEBp NEO2[ZFKSzVyIE2gNE4xOSEQvF2= M2LlclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUK2NFI4Lz5{MUGyOlAzPzxxYU6=
HeLa M2nIZmN6fG:2b4jpZ4l1gSCjc4PhfS=> NULwXWZbPDhidH:gO|IhcA>? Ml;iTWM2OCB;IECuNFIh|ryP MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTF{NkCyO{c,OjFzMk[wNlc9N2F-
SW620 M4r0bWN6fG:2b4jpZ4l1gSCjc4PhfS=> NIe5bGQ1QCC2bzC3NkBp MmPUTWM2OCB;IECuNFMh|ryP NVfqZWtxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNlYxOjdpPkKxNVI3ODJ5PD;hQi=>
HCT116 NXnDeIl7S3m2b4TvfIlkcXS7IHHzd4F6 MoXrO|IhcA>? MoC3TWM2OCB;IECuNFAyOyEQvF2= NW\nXVdRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxOFQ4PTZpPkKxNVQ1PzV4PD;hQi=>
CCRF-CEM NUnKd4t2S3m2b4TvfIlkcXS7IHHzd4F6 NUiyPJQyPzJiaB?= MmmxTWM2OCB;IECuNFA{KM7:TR?= NInkXYs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUG0OFc2Pid-MkGxOFQ4PTZ:L3G+
MX1 MknTR5l1d3SxeHnjbZR6KGG|c3H5 NVf3bZNLPzJiaB?= NFX2XHFKSzVyIE2gNE4xOzVizszN NUTVcYFIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxOFQ4PTZpPkKxNVQ1PzV4PD;hQi=>
chemoresistant DG75 NXjWUYR7S3m2b4TvfIlkcXS7IHHzd4F6 NU\vPFhHPzJiaB?= NFnrR4pKSzVyIE2gNE4xOSEQvF2= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTJ{N{ewNkc,OjF{Mke3NFI9N2F-
chemosensitive MUTU-I NG\UZpZEgXSxdH;4bYNqfHliYYPzZZk> M1nPfVI1KGh? M1fqdGlEPTBiPTCwMlAyKM7:TR?= MoDnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{Mke3NFIoRjJzMkK3O|AzRC:jPh?=
HT1080 MmPnRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M2fuTVk3KGh? MX7JR|UxKD1iMD6wNFEzKM7:TR?= NF2wbVc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
A549 NGH1OpdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M4TKXFk3KGh? MnvUTWM2OCB;IECuNFA1PCEQvF2= MoDrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[0OlcoRjJzMkm2OFY4RC:jPh?=
A375 NIO2cYRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1jyeFk3KGh? NHPGOVhKSzVyIE2gNE4xODR4IN88US=> NHP1ZY49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
NCI-N87 NInPS5ZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MkHVPVYhcA>? M1XFc2lEPTBiPTCwMlAxPTlizszN M4K0Z|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkm2OFY4Lz5{MUK5OlQ3PzxxYU6=
MCF7 NVPsR|VTSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M2TmfVk3KGh? MnP5TWM2OCB;IECuNFIxPSEQvF2= MljvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[0OlcoRjJzMkm2OFY4RC:jPh?=
HeLa MXXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MkjJPVYhcA>? M1qzTmlEPTBiPTCwMlEh|ryP MoP6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[0OlcoRjJzMkm2OFY4RC:jPh?=
PANC1 MlHkRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NX;UPZp3QTZiaB?= MWrJR|UxKD1iMD6zPFQyKM7:TR?= M17QPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkm2OFY4Lz5{MUK5OlQ3PzxxYU6=
Bel7402 MYPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NVLxPJJ[QTZiaB?= Mo\hTWM2OCB;IECuOVc5OiEQvF2= Mkn4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[0OlcoRjJzMkm2OFY4RC:jPh?=
1A9 NGK2[3FCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NWrUdZFWOyCmYYnz MWTFSFUxKD1iMD6wNFIxQSEQvF2= Ml7XQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[1O|koRjJzMkm2OVc6RC:jPh?=
A549 NF7ZdZpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MYizJIRigXN? NVnCVo43TUR3MDC9JFAvODB{NU[g{txO MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTJ7NkW3PUc,OjF{OU[1O|k9N2F-
KB M4i0OmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MkjVN{Bl[Xm| M3\RVGVFPTBiPTCwMlAxOjh5IN88US=> MnjSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[1O|koRjJzMkm2OVc6RC:jPh?=
PC3 M2TV[2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MX2zJIRigXN? MVPFSFUxKD1iMD6wNFg5PyEQvF2= M2DT[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkm2OVc6Lz5{MUK5OlU4QTxxYU6=
KB Ml7lR5l1d3SxeHnjbZR6KGG|c3H5 M1rHXlczKGh? NFvC[HFIUTVyIE2gNE4xODR6NzFOwG0> MlrTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|MU[5O|coRjJzM{G2PVc4RC:jPh?=
DU145 M3n0UmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVHqbY8xPzJiaB?= M{\SPWdKPTBiPTCwMlAxPTV3IN88US=> NGDmc489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUOxOlk4Pyd-MkGzNVY6Pzd:L3G+
A549 MmH2R5l1d3SxeHnjbZR6KGG|c3H5 NVLuNId6PzJiaB?= NWfJRVdXT0l3MDC9JFAvODB3NUig{txO M1e0VFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{G2PVc4Lz5{MUOxOlk4PzxxYU6=
MES-SA M3XhV2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MYLJR|UxKD1iMD6wNFI6PiEQvF2= MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN{NE[4Okc,OjF|MkS2PFY9N2F-
MES-SA NHfYZ41CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M2KwTWlEPTBiPTCwMlAxOjl4IN88US=> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN{NE[4O{c,OjF|MkS2PFc9N2F-
SF295 NYGzPJFZSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Mmf6TWM2OCB;IECuNFI1PTVizszN NV7Ld4g{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzNlQ3QDdpPkKxN|I1Pjh5PD;hQi=>
MES-SA MYPDfZRwfG:6aXPpeJkh[XO|YYm= M13aTmlEPTBiPTCwMlAxOjl4IN88US=> MoTMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|MkS2PVIoRjJzM{K0OlkzRC:jPh?=
MCF7 M3GycGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4L5bVQ5KGh? NUe3e5dFUUN3MDC9JFAvODB4IN88US=> MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN2MUexPEc,OjF|NEG3NVg9N2F-
HT-29 MlyxR5l1d3SxeHnjbZR6KGG|c3H5 NFXKc5I1QCCq NV\MR3ZyUUN3MDC9JFAvODB5IN88US=> NWHveY52RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzOFE4OThpPkKxN|QyPzF6PD;hQi=>
K562 M1nOb2N6fG:2b4jpZ4l1gSCjc4PhfS=> NYnPcoE3PDhiaB?= NIXtcpVKSzVyIE2gNU4yPiEQvF2= NYm3NXJ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzOFI4OzVpPkKxN|QzPzN3PD;hQi=>
MCF7 M2XiWWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmLBOFghcA>? NHvGem9KSzVyIE2gNk4yOSEQvF2= NGr6dHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO0Nlc{PSd-MkGzOFI4OzV:L3G+
A549 MoX6R5l1d3SxeHnjbZR6KGG|c3H5 MYS0PEBp MnS3TWM2OCB;IEKuOFYh|ryP M2qxWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{SyO|M2Lz5{MUO0Nlc{PTxxYU6=
SGC NVHub3Q3S3m2b4TvfIlkcXS7IHHzd4F6 MUW0PEBp M3H6S2lEPTBiPTCzMlM1KM7:TR?= M{TQPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{SyO|M2Lz5{MUO0Nlc{PTxxYU6=
HCT116 NWHvflA{S3m2b4TvfIlkcXS7IHHzd4F6 NWnZ[|lZPDhiaB?= Mme2TWM2OCB;IESuN|ch|ryP NIjCdZk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO0Nlc{PSd-MkGzOFI4OzV:L3G+
multidrug-resistant K562 MlfER5l1d3SxeHnjbZR6KGG|c3H5 MVm0PEBp M4\uUGlEPTBiPTC1MlY{KM7:TR?= MlrUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|NEK3N|UoRjJzM{SyO|M2RC:jPh?=
CCRF-CEM M3TOUGN6fG:2b4jpZ4l1gSCjc4PhfS=> MnLiO|IhcA>? MmjhTWM2OCB;IECuNFA{KM7:TR?= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN3NkW5Nkc,OjF|NU[1PVI9N2F-
taxol-resistant CCRF-CEM MkTNR5l1d3SxeHnjbZR6KGG|c3H5 NY\tb5ViPzJiaB?= M2Lab2lEPTBiPTCwMlQ{KM7:TR?= MoTKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|NU[1PVIoRjJzM{W2OVkzRC:jPh?=
vinblastine-resistant CCRF-CEM M1ztS2N6fG:2b4jpZ4l1gSCjc4PhfS=> NGfTdJQ4OiCq M{DJfmlEPTBiPTCxMlI4KM7:TR?= MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN3NkW5Nkc,OjF|NU[1PVI9N2F-
KB MkjMR5l1d3SxeHnjbZR6KGG|c3H5 NGDxTpk{KGSjeYO= NEf4d5JIUTVyIE2gNE4xODVzNjFOwG0> M2H5V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{e3N|Y5Lz5{MUO3O|M3QDxxYU6=
DU145 NX3rXFNNS3m2b4TvfIlkcXS7IHHzd4F6 NH72TI4{KGSjeYO= MVrHTVUxKD1iMD6wNFUzOyEQvF2= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN5N{O2PEc,OjF|N{ezOlg9N2F-
A549 MlHaR5l1d3SxeHnjbZR6KGG|c3H5 MlnmN{Bl[Xm| MYjHTVUxKD1iMD6wNFc3KM7:TR?= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN5N{O2PEc,OjF|N{ezOlg9N2F-
A2780 MlvCR5l1d3SxeHnjbZR6KGG|c3H5 NVv6VHVJOjRiaB?= M4nzSWlEPTBiPTCwMlAxODh{IN88US=> NYrITIlXRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzPVY4PDdpPkKxN|k3PzR5PD;hQi=>
A2780AD Ml7CR5l1d3SxeHnjbZR6KGG|c3H5 NUnrdW1VOjRiaB?= NXWzfGlnUUN3MDC9JFAvQTR7IN88US=> MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN7Nke0O{c,OjF|OU[3OFc9N2F-
HT-29 MmjJR5l1d3SxeHnjbZR6KGG|c3H5 Mkf3N{Bl[Xm| MnvXSWQ2OCB;IECuNFAxOSEQvF2= NHrBPXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUSyPFM4PSd-MkG0Nlg{PzV:L3G+
MCF7 NHXkTJZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1TVUFczKGh? MXfJR|UxKD1iMD6wNFIh|ryP NWSybHF6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0OFA1PDlpPkKxOFQxPDR7PD;hQi=>
HeLa M{LiW2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmnQOFghcA>? NFu5[FNKSzVyIE2gNE4xODJ4IN88US=> NVntbHplRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0OFY3QTlpPkKxOFQ3Pjl7PD;hQi=>
HT-29 NIDKSHdEgXSxdH;4bYNqfHliYYPzZZk> MnXjOFghcA>? MmjZTWM2OCB;IECuNFA{KM7:TR?= M4XuclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNES2Olk6Lz5{MUS0OlY6QTxxYU6=
KB MUXD[YxtKGO7Y3zlJIFzemW|dDDhd5NigQ>? NVWwNGQ5TUN3MDC9JFAvODB{IN88US=> NWrlfWRLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFA3OjZpPkKxOFgxPjJ4PD;hQi=>
A549 Mn7XRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MkDnO|IhcA>? NVrRN4F{UUN3MDC9JFAvODB{MzFOwG0> MmTmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF2OEC2NlYoRjJzNEiwOlI3RC:jPh?=
HT-29 NGjUTWRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MlO1O|IhcA>? NH7aZXNKSzVyIE2gNE4xODZzIN88US=> MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTR6ME[yOkc,OjF2OEC2NlY9N2F-
A431 NV;HXXBySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NV71XmE2PzJiaB?= M2m2e2lEPTBiPTCwMlAxQTJizszN NU\JVFlvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG0PFA3OjZpPkKxOFgxPjJ4PD;hQi=>
SKOV3 NWnrOJZDSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MW[3NkBp NWC3V5VKUUN3MDC9JFAvODF2NTFOwG0> M3S4blxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNEiwOlI3Lz5{MUS4NFYzPjxxYU6=
NCI-H460 NWHYXHo1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M2XwR|czKGh? NI\1fHpKSzVyIE2gNE4xOTR4IN88US=> NGL2[W89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUS4NFYzPid-MkG0PFA3OjZ:L3G+
MCF7 MnvvR5l1d3SxeHnjbZR6KGG|c3H5 NFm4emY1QCCq MYfHTVUxKD1iMD6wNVIh|ryP MmLKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
HT-29 MVnDfZRwfG:6aXPpeJkh[XO|YYm= NX:wUodPPDhiaB?= MV;HTVUxKD1iMD6wNVIh|ryP M{ftU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUGzNlk1Lz5{MUWxN|I6PDxxYU6=
SF268 Mn\HR5l1d3SxeHnjbZR6KGG|c3H5 M1n2R|Q5KGh? Mk\ZS2k2OCB;IECuNFEzKM7:TR?= NFXZbYI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN|I6PCd-MkG1NVMzQTR:L3G+
H460 M3PqbWN6fG:2b4jpZ4l1gSCjc4PhfS=> MXe0PEBp M{DvVmdKPTBiPTCwMlAzPCEQvF2= NGKxdXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWxN|I6PCd-MkG1NVMzQTR:L3G+
CHOK1 MULDfZRwfG:6aXPpeJkh[XO|YYm= NWDnSm9iPDhiaB?= MWnHTVUxKD1iNT65JO69VQ>? MoK4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3MUOyPVQoRjJzNUGzNlk1RC:jPh?=
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SH-SY5Y NIW0fohEgXSxdH;4bYNqfHliYYPzZZk> M321VVI1KGh? MlrGTWM2OCB;IEiuOVYh|ryP NVzWb2RiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1NVQxOTVpPkKxOVE1ODF3PD;hQi=>
BGC823 NYDzfYxpS3m2b4TvfIlkcXS7IHHzd4F6 MnHENlQhcA>? M4G0fGlEPTBiPTC5MlI1KM7:TR?= M3rkfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUG0NFE2Lz5{MUWxOFAyPTxxYU6=
A2780 NUGxdmFUS3m2b4TvfIlkcXS7IHHzd4F6 MojrO|IhcA>? NXTGSGE6UUN3MDC9JFAvODBzIN88US=> M{LNOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUOwNlUyLz5{MUWzNFI2OTxxYU6=
BGC823 NFvYXGNEgXSxdH;4bYNqfHliYYPzZZk> NGjNT|k4OiCq MoDSTWM2OCB;IECuNFAyKM7:TR?= NHLoRWs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWzNFI2OSd-MkG1N|AzPTF:L3G+
Bel7402 NFXxTGlEgXSxdH;4bYNqfHliYYPzZZk> M3L5SlczKGh? MWTJR|UxKD1iMD6wNFYh|ryP NXT0fJZ[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1N|AzPTFpPkKxOVMxOjVzPD;hQi=>
A549 NH7De5JEgXSxdH;4bYNqfHliYYPzZZk> MYK3NkBp NELpNIZKSzVyIE2gNE4xOTZizszN M4KxflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUOwNlUyLz5{MUWzNFI2OTxxYU6=
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SW480 MmLBR5l1d3SxeHnjbZR6KGG|c3H5 MlHkOFghcA>? M3;FdmlEPTBiPTCwMlAxQCEQvF2= MlnjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3M{S1N|koRjJzNUO0OVM6RC:jPh?=
SMMC7721 NYLRdnBnS3m2b4TvfIlkcXS7IHHzd4F6 NHi1Smo1QCCq MlT0TWM2OCB;IECuNFA5KM7:TR?= NFnmbYo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUWzOFU{QSd-MkG1N|Q2Ozl:L3G+
A549 MYjDfZRwfG:6aXPpeJkh[XO|YYm= NYP0XJF1PDhiaB?= MlXMTWM2OCB;IECuNFA5KM7:TR?= M3jhXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUO0OVM6Lz5{MUWzOFU{QTxxYU6=
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HL60 MmPaR5l1d3SxeHnjbZR6KGG|c3H5 Mn\XOFghcA>? MYnJR|UxKD1iMD6wNUDPxE1? Mk\5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3M{S1N|koRjJzNUO0OVM6RC:jPh?=
OVCAR8 MXPBcpRq[2GwY3XyJIF{e2G7 Mn7tPVYhcA>? NXz5VXVYUUN3MDC9JFAvODB2NzFOwG0> NYW4VlVERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG1OVc2OzhpPkKxOVU4PTN6PD;hQi=>
NCI/ADR-RES NX3pUI14SW62aXPhcoNmeiCjc4PhfS=> NYfrd4x[QTZiaB?= NVHSbVFGUUN3MDC9JFYvOjZ|IN88US=> M3TofVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNUW3OVM5Lz5{MUW1O|U{QDxxYU6=
NCI-H460 NHHC[nJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MYq0PEBp MnL5TWM2OCB;IECuNFA1KM7:TR?= MlTXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF3NkO3OVAoRjJzNU[zO|UxRC:jPh?=
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B16F0 NIPofWZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M2L5UlQ5KGh? NFrrWlJKSzVyIE2gNE4xOjhizszN M1n6U|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNkC0O|Q3Lz5{MU[wOFc1PjxxYU6=
P388D1 NGPSU|VCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1PGdlQ5KGh? MXzJR|UxKD1iMD6wN|Uh|ryP NV3MN3NWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2NFQ4PDZpPkKxOlA1PzR4PD;hQi=>
CHO-VV 3-2 NGTiVpFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MXm0PEBp NXTqVJJWUUN3MDC9JFAvOTRizszN MnmyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF4MES3OFYoRjJzNkC0O|Q3RC:jPh?=
CHO M3raUmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MkC2OFghcA>? MljTTWM2OCB;IECuNVch|ryP MorJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF4MES3OFYoRjJzNkC0O|Q3RC:jPh?=
CHO-TAX 5-6 MoDBRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NI\qWGI1QCCq NYLkUpdrUUN3MDC9JFAvPTJizszN MnvtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF4MES3OFYoRjJzNkC0O|Q3RC:jPh?=
CEM/VLB NVTzPXdxSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWjPfFhFPDhiaB?= MYDJR|UxKD1iMz6zOEDPxE1? MkS2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF4MES3OFYoRjJzNkC0O|Q3RC:jPh?=
A549 MVrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NH\DPW44OiCq M2\IfWlEPTBiPTCwMlAxPzJizszN NWTIeYYzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2OlM{OTlpPkKxOlY{OzF7PD;hQi=>
taxol-resistant A549-T12 MljQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NEXVR3c4OiCq NULvbZJ6UUN3MDC9JFAvODd3MjFOwG0> NW\sNGl1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2OlM{OTlpPkKxOlY{OzF7PD;hQi=>
MCF7 MlXRR5l1d3SxeHnjbZR6KGG|c3H5 NVz0WnZ[PDhiaB?= NXSxTZJPUUN3MDC9JFAvODB{NTFOwG0> NHu1TGc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MU[4NFE6OCd-MkG2PFAyQTB:L3G+
MCF7/VP M4m3OmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3X6fFQ5KGh? NEG4eXdKSzVyIE2gNE4xODJ6IN88US=> MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZ6MEG5NEc,OjF4OECxPVA9N2F-
NCI/ADR MnfMR5l1d3SxeHnjbZR6KGG|c3H5 MnHiOFghcA>? MXHJR|UxKD1iMj63JO69VQ>? M1i0RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNkiwNVkxLz5{MU[4NFE6ODxxYU6=
LT12 MonQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NYL5S|F3PDhiaB?= MWjJR|UxKD1iMD6wNFYh|ryP MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTdyNUKyN{c,OjF5MEWyNlM9N2F-
NCI-H460 MonJR5l1d3SxeHnjbZR6KGG|c3H5 NFvJTJE1QCCq NGHzS5lKSzVyIE2gNE4xOSEQvF2= NHLG[pI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUewOVIzOyd-MkG3NFUzOjN:L3G+
SF268 NYf5eFZlS3m2b4TvfIlkcXS7IHHzd4F6 M{D4U|Q5KGh? M{PmOmlEPTBiPTCwMlAyKM7:TR?= MmjJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5MEWyNlMoRjJzN{C1NlI{RC:jPh?=
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SKOV3 NF;rXW9EgXSxdH;4bYNqfHliYYPzZZk> NW\Bc21uPDhiaB?= MmLETWM2OCB;IECuNFEh|ryP MoL2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5MEWyNlMoRjJzN{C1NlI{RC:jPh?=
RKOp27 MWTDfZRwfG:6aXPpeJkh[XO|YYm= NWS3fWJmPDhiaB?= M{KwV2lEPTBiPTCwMlAyKM7:TR?= MlHkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5MEWyNlMoRjJzN{C1NlI{RC:jPh?=
P388 M{XNUWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MkPIOFghcA>? NHPibYdKSzVyIE2gNE4xPCEQvF2= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTdyNUKyN{c,OjF5MEWyNlM9N2F-
L1210 MXfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M4LjUVQ5KGh? MnzVTWM2OCB;IECuNFYh|ryP MoHSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5MEWyNlMoRjJzN{C1NlI{RC:jPh?=
NCI-H460 MoPFRY51cWOjbnPldkBie3OjeR?= MUm3NkBp MWLJR|MxKD1iMz62JO69VQ>? NH\zb2I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUewO|A1Pid-MkG3NFcxPDZ:L3G+
A2780 MoT6R5l1d3SxeHnjbZR6KGG|c3H5 M3i5SVQ5KGh? NHLlSlJKSzVyIE2gNE4xODB4MjFOwG0> NUjrcmhGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3OlQ{ODhpPkKxO|Y1OzB6PD;hQi=>
A2780AD MlLjR5l1d3SxeHnjbZR6KGG|c3H5 MlPmOFghcA>? NF33[o1KSzVyIE2gNU46KM7:TR?= MnXHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5NkSzNFgoRjJzN{[0N|A5RC:jPh?=
786-0 NF3ZV|BCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NFS2N3FKSzVyIE2gNE4xODRizszN NYXicIF5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|Q1QTlpPkKxO|c1PDl7PD;hQi=>
PC3 M3vrcmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NELYR4xKSzVyIE2gNE4xODB2MzFOwG0> MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTd5NUG1NEc,OjF5N{WxOVA9N2F-
DU145 M1X2RWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M2jBR2lEPTBiPTCwMlAxOjNizszN M1j4TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzN{e1NVUxLz5{MUe3OVE2ODxxYU6=
MDA-MB-435 MULBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NEX5bJBKSzVyIE2gNE4xOTZizszN NYjFc2xTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|UyPTBpPkKxO|c2OTVyPD;hQi=>
MCF7 MU\DfZRwfG:6aXPpeJkh[XO|YYm= NEfDVHQ1QCCq Ml7GTWM2OCB;IECuNFAyPjJizszN M1jXeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzN{e5OVE6Lz5{MUe3PVUyQTxxYU6=
COLO205 NYTVOGlpS3m2b4TvfIlkcXS7IHHzd4F6 MUS0PEBp NETDfmxKSzVyIE2gNE4xODN|MTFOwG0> NU[0S4ZCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|k2OTlpPkKxO|c6PTF7PD;hQi=>
KB MmG3R5l1d3SxeHnjbZR6KGG|c3H5 NFKwNm1KSzVyIE2gOk43QDRizszN MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTd6NE[zNUc,OjF5OES2N|E9N2F-
DU145 MnftR5l1d3SxeHnjbZR6KGG|c3H5 NHHZZ4ZKSzVyIE2gPE43OjZizszN NXq0dpE5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3PFQ3OzFpPkKxO|g1PjNzPD;hQi=>
A549 MnHNR5l1d3SxeHnjbZR6KGG|c3H5 NIfzfG9KSzVyIE2gPU4zPjVizszN MlHkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5OES2N|EoRjJzN{i0OlMyRC:jPh?=
HeLa MmXWRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MVnJR|UxKD1iMD6wNFE{QCEQvF2= NF:zVJc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe4Olc6Oyd-MkG3PFY4QTN:L3G+
SKOV3 NFXBXlVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NETaV|dKSzVyIE2gNE4xODJ7NTFOwG0> NYDUc5hWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3PFY4QTNpPkKxO|g3Pzl|PD;hQi=>
HeLa NXnlbmJiSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M{DZeFQ5KGh? NVmxVVBGUUN3MDC9JFAvODBzMjFOwG0> NX;YbXQ3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4NFA5OzlpPkKxPFAxQDN7PD;hQi=>
A2780 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NF3KVYIzKGSjeYO= M1vDS2lEPTBiPTCwMlAyPCEQvF2= M4LpRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOECyPVU4Lz5{MUiwNlk2PzxxYU6=
Hep3B2 NGjHfWpEgXSxdH;4bYNqfHliYYPzZZk> NUjo[oxUPzJiaB?= NITUSlhKSzVyIE2gNE4xODByMU[g{txO MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOThzMkSxNEc,OjF6MUK0NVA9N2F-
PANC1 M4Ht[WN6fG:2b4jpZ4l1gSCjc4PhfS=> M3XxelczKGh? MYrJR|UxKD1iMD6wNFEyKM7:TR?= MmTmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6MUK0NVAoRjJzOEGyOFExRC:jPh?=
CNE1-LMP1 MWrDfZRwfG:6aXPpeJkh[XO|YYm= NGrMOng4OiCq MYDJR|UxKD1iMD6wNFQzKM7:TR?= M3Hoe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFExLz5{MUixNlQyODxxYU6=
MGC M4P0eGN6fG:2b4jpZ4l1gSCjc4PhfS=> MnfWO|IhcA>? NIDM[W1KSzVyIE2gNE4xODZ2IN88US=> MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOThzMkSxNEc,OjF6MUK0NVA9N2F-
A375 NFvBWXVEgXSxdH;4bYNqfHliYYPzZZk> Mm\qO|IhcA>? NH3VSoNKSzVyIE2gNE4xODh7IN88US=> M3iwSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFExLz5{MUixNlQyODxxYU6=
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A549 MW\DfZRwfG:6aXPpeJkh[XO|YYm= MnzRO|IhcA>? NFvZWHhKSzVyIE2gNE4xOyEQvF2= NWnwNmtlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4NVI1OTBpPkKxPFEzPDFyPD;hQi=>
EC109 MnrRR5l1d3SxeHnjbZR6KGG|c3H5 MV23NkBp MUXJR|UxKD1iMD6xOEDPxE1? M1vRZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFExLz5{MUixNlQyODxxYU6=
MES-SA Mk[5R5l1d3SxeHnjbZR6KGG|c3H5 MnfvPVYhcA>? NWfwe203UUN3MDC9JFAvODB2IN88US=> M{fUVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFIyLz5{MUixNlQzOTxxYU6=
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SNB75 NIH0VIpEgXSxdH;4bYNqfHliYYPzZZk> MYHHTVUxKD1iMD6wNFQh|ryP M1HVe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEO5OlQxLz5{MUizPVY1ODxxYU6=
KM12 NFy3bm5EgXSxdH;4bYNqfHliYYPzZZk> NXjzNmJwT0l3MDC9JFAvODB2IN88US=> NVTPUnhORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4N|k3PDBpPkKxPFM6PjRyPD;hQi=>
DU145 NXnLOIxvS3m2b4TvfIlkcXS7IHHzd4F6 NEnCSINIUTVyIE2gNE4xODVizszN MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh|OU[0NEc,OjF6M{m2OFA9N2F-
SKOV3 MXnDfZRwfG:6aXPpeJkh[XO|YYm= MmHmS2k2OCB;IECuNFA5KM7:TR?= NUnmdplnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4N|k3PDBpPkKxPFM6PjRyPD;hQi=>
NCI-H322M M2P3T2N6fG:2b4jpZ4l1gSCjc4PhfS=> NEfWSppIUTVyIE2gNE4xOTNizszN M1LxT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEO5OlQxLz5{MUizPVY1ODxxYU6=
UACC257 MoX2R5l1d3SxeHnjbZR6KGG|c3H5 NWn1RpI5T0l3MDC9JFAvODRizszN M1L2Z|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEO5OlQxLz5{MUizPVY1ODxxYU6=
HCT15 NVizWVFSS3m2b4TvfIlkcXS7IHHzd4F6 MXPHTVUxKD1iMD6xOVgh|ryP NHTEeZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
ACHN MVzDfZRwfG:6aXPpeJkh[XO|YYm= M4jP[mdKPTBiPTCwMlM6QCEQvF2= NVzpbpk4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4N|k3PDBpPkKxPFM6PjRyPD;hQi=>
HL60 NFi5XpFEgXSxdH;4bYNqfHliYYPzZZk> NEDwXng4OiCq NYjlZ|VzUUN3MDC9JFAvODB|NDFOwG0> M4i3ZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOES4NlY5Lz5{MUi0PFI3QDxxYU6=
MCF7 NIjxO3ZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHy2NZU6PiCq MkLYTWM2OCB;IECuNFAxQTFizszN NIDXcWQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3NFc6PSd-MkG4O|A4QTV:L3G+
A549 NFnjXplCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NWKxRphlPzJiaB?= MV\JR|UxKD1iMD6wNFMyPCEQvF2= NYHHUHJRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|A4QTVpPkKxPFcxPzl3PD;hQi=>
A549 Mk\wR5l1d3SxeHnjbZR6KGG|c3H5 M{XXN|I1KGh? M2rYR2VEPTBiPTCwMlAxPDZizszN M3TwflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEezNFY5Lz5{MUi3N|A3QDxxYU6=
KB NUHHO5JoS3m2b4TvfIlkcXS7IHHzd4F6 NYPlfoduUUN3MDC9JFAvODhizszN M1n0V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEe1O|Y1Lz5{MUi3OVc3PDxxYU6=
786-0 M4TXVmN6fG:2b4jpZ4l1gSCjc4PhfS=> MlezTWM2OCB;IECuNFgh|ryP Moe5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6N{W3OlQoRjJzOEe1O|Y1RC:jPh?=
OS-RC2 NYCyZ3hyS3m2b4TvfIlkcXS7IHHzd4F6 MVnJR|UxKD1iMD6wPEDPxE1? NVLNcZlHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|U4PjRpPkKxPFc2PzZ2PD;hQi=>
22Rv1 NUnsT5dOS3m2b4TvfIlkcXS7IHHzd4F6 MlziTWM2OCB;IECuNFgh|ryP NG\kdWI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3OVc3PCd-MkG4O|U4PjR:L3G+
HepG2 MVnDfZRwfG:6aXPpeJkh[XO|YYm= M3;T[2lEPTBiPTCwMlA5KM7:TR?= NUHLS5UyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|U4PjRpPkKxPFc2PzZ2PD;hQi=>
HT-29 M3K0[WN6fG:2b4jpZ4l1gSCjc4PhfS=> NELkZ|hKSzVyIE2gNE4{QCEQvF2= M1XIXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEe1O|Y1Lz5{MUi3OVc3PDxxYU6=
A375 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MXTJR|UxKD1iMD64NUDPxE1? M4jaTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEe1O|Y1Lz5{MUi3OVc3PDxxYU6=
MCF7 NX3LbIZNS3m2b4TvfIlkcXS7IHHzd4F6 NFjwWVZKSzVyIE2gNU4{KM7:TR?= NHXNVZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3OVc3PCd-MkG4O|U4PjR:L3G+
BGC823 Mk[2R5l1d3SxeHnjbZR6KGG|c3H5 NIT0bVhKSzVyIE2gNU42KM7:TR?= MoL5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6N{W3OlQoRjJzOEe1O|Y1RC:jPh?=
769-P MWrDfZRwfG:6aXPpeJkh[XO|YYm= M2POV2lEPTBiPTC3MlEh|ryP NE\0d|g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3OVc3PCd-MkG4O|U4PjR:L3G+
MCF7 M4jDPWN6fG:2b4jpZ4l1gSCjc4PhfS=> NGm1enY{KGSjeYO= M{PrbGdKPTBiPTCxMlA4KM7:TR?= MkLtQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6OEmzOFEoRjJzOEi5N|QyRC:jPh?=
PC3 M{jGZWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYXEfY9vOyCmYYnz MUXHTVUxKD1iMT60OkDPxE1? NHfkUGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi4PVM1OSd-MkG4PFk{PDF:L3G+
SK-N-SH MUXDfZRwfG:6aXPpeJkh[XO|YYm= NYCyT|RuOyCmYYnz NVXpNoN5T0l3MDC9JFIvOTlizszN M1LQ[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEi5N|QyLz5{MUi4PVM1OTxxYU6=
HeLa MmfpR5l1d3SxeHnjbZR6KGG|c3H5 NFW1OHo{KGSjeYO= MVvHTVUxKD1iMj64NkDPxE1? NXW5ZXY{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4PFk{PDFpPkKxPFg6OzRzPD;hQi=>
CHO-VV 3-2 Mm\vRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NGLEPXg1QCCq MlrOTWM2OCB;IECuNVQh|ryP M3jycFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUKwOlM5Lz5{MUmyNFY{QDxxYU6=
CHO-TAX 5-6 MnHNRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MoTiOFghcA>? NWnTV5FlUUN3MDC9JFAvPTJizszN M3f6bFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUKwOlM5Lz5{MUmyNFY{QDxxYU6=
multidrug-resistant CEM/VLB MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MYm0PEBp NHr1XlhKSzVyIE2gN{4{PCEQvF2= MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl{ME[zPEc,OjF7MkC2N|g9N2F-
BGC823 MWPDfZRwfG:6aXPpeJkh[XO|YYm= M{jOOmlEPTBiPTCwMlAxOzJ7IN88US=> NUX0TZZ2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5Nlg4QTdpPkKxPVI5Pzl5PD;hQi=>
HT-29 M1W0bmN6fG:2b4jpZ4l1gSCjc4PhfS=> M{POU2lEPTBiPTCwMlAxOzl2IN88US=> MmSzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7Mki3PVcoRjJzOUK4O|k4RC:jPh?=
HepG2 Mm\ER5l1d3SxeHnjbZR6KGG|c3H5 Moe3TWM2OCB;IECuNFA1PCEQvF2= NEHnS3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmyPFc6Pyd-MkG5Nlg4QTd:L3G+
A375 M17s[WN6fG:2b4jpZ4l1gSCjc4PhfS=> M4LPemlEPTBiPTCwMlAxPDlizszN M2L1PFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUK4O|k4Lz5{MUmyPFc6PzxxYU6=
A549 MXPDfZRwfG:6aXPpeJkh[XO|YYm= NHz2[JNKSzVyIE2gNE4xPDR7IN88US=> NHfuSVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmyPFc6Pyd-MkG5Nlg4QTd:L3G+
NCI-H460 M4XKTmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVqzTWRRUUN3MDC9JFgh|ryP MlPrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7NEK3OlUoRjJzOUSyO|Y2RC:jPh?=
A549 NWT6RYo1S3m2b4TvfIlkcXS7IHHzd4F6 MlrtOFghcA>? NWjBTmNFUUN3MDC9JFAvODFizszN Mlz2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7N{OwOVQoRjJzOUezNFU1RC:jPh?=
HeLa M13QNWN6fG:2b4jpZ4l1gSCjc4PhfS=> M1zUfFQ5KGh? NGmxe5JKSzVyIE2gNE43KM7:TR?= MlntQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7N{OwOVQoRjJzOUezNFU1RC:jPh?=
HT-29 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NGjKXZM{KGSjeYO= MonFSWQ2OCB;IECuNFA3KM7:TR?= NGLITJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm3N|ExOSd-MkG5O|MyODF:L3G+
HBL100 NYT2WpROT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3f5TGdKPTBiPTCwMlAxODBzNzFOwG0> MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl6NkW4OUc,OjF7OE[1PFU9N2F-
HeLa MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{PrbGdKPTBiPTCwMlAxODB|MzFOwG0> MkjYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7OE[1PFUoRjJzOUi2OVg2RC:jPh?=
T47D MkTPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWfHTVUxKD1iMD6wNFAyPSEQvF2= NH7RVHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm4OlU5PSd-MkG5PFY2QDV:L3G+
WiDr NVG5[WpzT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MX7HTVUxKD1iMD6wNFAzOiEQvF2= NHXPOmE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm4OlU5PSd-MkG5PFY2QDV:L3G+
A2780 MVHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1XsXWdKPTBiPTCwMlAxODJ5IN88US=> Ml\MQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7OE[1PFUoRjJzOUi2OVg2RC:jPh?=
SW1573 NFLEXHpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MVXHTVUxKD1iMD6wNFUh|ryP NEnocIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUm4OlU5PSd-MkG5PFY2QDV:L3G+
A2780 NEfic4pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MYfJR|UxKD1iMD6wNVch|ryP Mn3OQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7OUW1OFIoRjJzOUm1OVQzRC:jPh?=
A549 M1PtemFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MkjsO|IhcA>? NWnXfmExUUN3MDC9JFAvODB5MjFOwG0> NX;HZXZKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwNlcyODBpPkKyNFI4OTByPD;hQi=>
taxol-resistant A549-T12 MUHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NFrsfFg4OiCq M{nac2lEPTBiPTCwMlA4PSEQvF2= MoDOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJyMkexNFAoRjJ{MEK3NVAxRC:jPh?=
OVCAR8 MoDDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NWHaTW5LQTZiaB?= NGPldZNKSzVyIE2gNE4xODJizszN MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB2NEG2OEc,OjJyNESxOlQ9N2F-
NCI-ADR-RES M2f5eGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGjTW2c6PiCq MXXJR|UxKD1iMT61JO69VQ>? NWW5cpZKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwOFQyPjRpPkKyNFQ1OTZ2PD;hQi=>
KB M{Hs[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWi3NkBp MmW5TWM2OCB;IECuNFA{OyEQvF2= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB4MECzN{c,OjJyNkCwN|M9N2F-
KB-7d MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2DGN|czKGh? Ml3uTWM2OCB;IECuNFA4QSEQvF2= NHXySIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC2NFA{Oyd-MkKwOlAxOzN:L3G+
KB-S15 NEfZclhIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2fOU|czKGh? NYTNXlFsUUN3MDC9JFAvOjd|IN88US=> NFryfZQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC2NFA{Oyd-MkKwOlAxOzN:L3G+
A2780 NIH1eGpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= Mo\MNkBl[Xm| M3rG[GlEPTBiPTCwMlAyPSEQvF2= NVXzWYdpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwO|E2OjZpPkKyNFcyPTJ4PD;hQi=>
KB M3nKOWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{DvZlQ5KGh? M3nTfGlEPTBiPTCwMlAxPDVizszN M2L2OFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEe0NlU4Lz5{MkC3OFI2PzxxYU6=
L1210 M33ZRWN6fG:2b4jpZ4l1gSCjc4PhfS=> NWPsdItpPDhiaB?= MUDJR|UxKD1iMD6xNkDPxE1? M1nQe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEe0NlU4Lz5{MkC3OFI2PzxxYU6=
A2780 MojORY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NUjRdnkzOiCmYYnz Moj4TWM2OCB;IECuNFIh|ryP M{LHVVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUO2OVI{Lz5{MkGzOlUzOzxxYU6=
DU145 NFjDXoJEgXSxdH;4bYNqfHliYYPzZZk> M1fwW2VEPTBiPTCwMlAxPTlizszN MnLTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzNEK1OFMoRjJ{MUSyOVQ{RC:jPh?=
KB MU\DfZRwfG:6aXPpeJkh[XO|YYm= MoX2SWM2OCB;IECuNFA3KM7:TR?= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF2MkW0N{c,OjJzNEK1OFM9N2F-
A549 MWjDfZRwfG:6aXPpeJkh[XO|YYm= MnHxSWM2OCB;IECuNFA3PCEQvF2= MmjTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzNEK1OFMoRjJ{MUSyOVQ{RC:jPh?=
QGY7701 M4XkdWN6fG:2b4jpZ4l1gSCjc4PhfS=> M2DoflczKGh? NFXse2lKSzVyIE2gNE4xPCEQvF2= M4DRPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MUWzN|M5Lz5{MkG1N|M{QDxxYU6=
HepG2 MmGxR5l1d3SxeHnjbZR6KGG|c3H5 MUW3NkBp MVrJR|UxKD1iMD6wOUDPxE1? MVi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF3M{OzPEc,OjJzNUOzN|g9N2F-
Bel7404 MnXRR5l1d3SxeHnjbZR6KGG|c3H5 NELNVIE4OiCq MULJR|UxKD1iMD64NkDPxE1? MnfsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzNUOzN|goRjJ{MUWzN|M5RC:jPh?=
SMMC7721 M1;vc2N6fG:2b4jpZ4l1gSCjc4PhfS=> MVS3NkBp NWnuVnpIUUN3MDC9JFAvQDhizszN MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF3M{OzPEc,OjJzNUOzN|g9N2F-
Bel7402 M3PlZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MknSO|IhcA>? M1HjVmlEPTBiPTCxMlI2KM7:TR?= NHzv[mM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkG1N|M{QCd-MkKxOVM{Ozh:L3G+
MCF7 NVvaS2RHS3m2b4TvfIlkcXS7IHHzd4F6 NH7YWpkzPCC2bzC0PEBp MUDJR|UxKD1iMD6wNFMh|ryP M3Hqe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkKyNFQxLz5{MkKyNlA1ODxxYU6=
SH-SY5Y MkXGR5l1d3SxeHnjbZR6KGG|c3H5 MmjQNlQhfG9iNEigbC=> M{fB[mlEPTBiPTCwMlAxPCEQvF2= NEDVeZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKyNlA1OCd-MkKyNlIxPDB:L3G+
HepG2 NEL4WJdEgXSxdH;4bYNqfHliYYPzZZk> NUHueYR5OjRidH:gOFghcA>? Mk\DTWM2OCB;IECuNFA4KM7:TR?= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJ{MkC0NEc,OjJ{MkKwOFA9N2F-
H460 MWfDfZRwfG:6aXPpeJkh[XO|YYm= MlrxNlQhfG9iNEigbC=> MoDhTWM2OCB;IECuNFA5KM7:TR?= M2jLdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkKyNFQxLz5{MkKyNlA1ODxxYU6=
HT-29 M3vLb2N6fG:2b4jpZ4l1gSCjc4PhfS=> MVqzJIRigXN? NV24W4oyUUN3MDC9JFAvODB4IN88US=> M3LOXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkO5OlAyLz5{MkKzPVYxOTxxYU6=
DU145 MVjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M3vvRlczKGh? MYjHTVUxKD1iMD6wNFM5PiEQvF2= MkDhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{NkW2PFUoRjJ{Mk[1Olg2RC:jPh?=
KB MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MlHQO|IhcA>? NGHyfmhIUTVyIE2gNE4xODRzMjFOwG0> MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJ4NU[4OUc,OjJ{NkW2PFU9N2F-
A549 M2\3XGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NXvUVGlnPzJiaB?= M{Kxb2dKPTBiPTCwMlAxPTR4IN88US=> MnW5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{NkW2PFUoRjJ{Mk[1Olg2RC:jPh?=
MCF7 Mki1R5l1d3SxeHnjbZR6KGG|c3H5 M3u3bFk3KGh? NVnEPFNxUUN3MDC9JFAvOSEQvF2= NUHKT2JrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKzOlA3OTNpPkKyN|YxPjF|PD;hQi=>
A549 MmfUR5l1d3SxeHnjbZR6KGG|c3H5 NGHVVlE4OiCq NWrSWG9iUUN3MDC9JFAvOTlizszN NVjydJlZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0O|IxPDNpPkKyOFczODR|PD;hQi=>
MCF7 NFG5RlREgXSxdH;4bYNqfHliYYPzZZk> NU[wdJUxPDhiaB?= MoXlTWM2OCB;IECuNFA3KM7:TR?= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR5MkC0OUc,OjJ2N{KwOFU9N2F-
K562 MU\DfZRwfG:6aXPpeJkh[XO|YYm= M1fIWVczKGh? NXT3OZdlUUN3MDC9JFAvPDFizszN Mk\rQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2OEOwPVAoRjJ{NEizNFkxRC:jPh?=
CaEs17 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MoP5O|IhcA>? NY\rWJViUUN3MDC9JFAvPDNizszN NVfuVHlURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0PFMxQTBpPkKyOFg{ODlyPD;hQi=>
MGC803 MkXkR5l1d3SxeHnjbZR6KGG|c3H5 MojZO|IhcA>? NWKyT5B7UUN3MDC9JFAvQDVizszN M{fBNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEizNFkxLz5{MkS4N|A6ODxxYU6=
HeLa NIPtSJNEgXSxdH;4bYNqfHliYYPzZZk> M3rVSlczKGh? M3[wdGlEPTBiPTCwMlg6KM7:TR?= NFT1U5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkS4N|A6OCd-MkK0PFMxQTB:L3G+
Bel7402 NXHER3lVS3m2b4TvfIlkcXS7IHHzd4F6 M2XHSlczKGh? NXHaTGVjUUN3MDC9JFEvQDlizszN NIXUVIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkS4N|A6OCd-MkK0PFMxQTB:L3G+
A549 NXTFdWJ5S3m2b4TvfIlkcXS7IHHzd4F6 NGTPOXU4OiCq MV;JR|UxKD1iMz60OkDPxE1? NIGxeFA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkS4N|A6OCd-MkK0PFMxQTB:L3G+
MCF7 NWSxUIZGS3m2b4TvfIlkcXS7IHHzd4F6 NGXVRXg4OiCq NVLmZm1tUUN3MDC9JFQvPzdizszN MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR6M{C5NEc,OjJ2OEOwPVA9N2F-
SKOV3 MnToR5l1d3SxeHnjbZR6KGG|c3H5 M4rMVWlEPTBiPTCwMlAxODFizszN NWiyU2w6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1NFY3OjBpPkKyOVA3PjJyPD;hQi=>
BGC823 MXrDfZRwfG:6aXPpeJkh[XO|YYm= NULX[Fk1UUN3MDC9JFAvODB|MzFOwG0> M2fUdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUC2OlIxLz5{MkWwOlYzODxxYU6=
HepG2 NWn4bIhJS3m2b4TvfIlkcXS7IHHzd4F6 M37xbmlEPTBiPTCwMlAxPDRizszN NELIO3c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwOlYzOCd-MkK1NFY3OjB:L3G+
A549 MlG0R5l1d3SxeHnjbZR6KGG|c3H5 MW\JR|UxKD1iMD6wNVYh|ryP Mnz6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3ME[2NlAoRjJ{NUC2OlIxRC:jPh?=
HCT8 MVfDfZRwfG:6aXPpeJkh[XO|YYm= MmThTWM2OCB;IECuNFUyKM7:TR?= MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVyNk[yNEc,OjJ3ME[2NlA9N2F-
CCRF-CEM MVvDfZRwfG:6aXPpeJkh[XO|YYm= NIrKNIc4OiCq NFvGWItKSzVyIE2gNE4xODF{IN88US=> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVyN{i5N{c,OjJ3MEe4PVM9N2F-
taxol-resistant CCRF-CEM M4q2fGN6fG:2b4jpZ4l1gSCjc4PhfS=> M1T1NFczKGh? M37JOWlEPTBiPTCwMlQ{KM7:TR?= MnX3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3MEe4PVMoRjJ{NUC3PFk{RC:jPh?=
vinblastine-resistant CCRF-CEM M4nobmN6fG:2b4jpZ4l1gSCjc4PhfS=> NIj0e|g4OiCq Mn61TWM2OCB;IEGuNlch|ryP NI[xdWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwO|g6Oyd-MkK1NFc5QTN:L3G+
BGC823 NYnZWlVzS3m2b4TvfIlkcXS7IHHzd4F6 MVq3NkBp MkDjTWM2OCB;IECuNFAyKM7:TR?= NWDycoFURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1PFMxPzlpPkKyOVg{ODd7PD;hQi=>
A2780 NXPjbo5RS3m2b4TvfIlkcXS7IHHzd4F6 Mn31O|IhcA>? MUXJR|UxKD1iMD6wNFEh|ryP NXLyd2lTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1PFMxPzlpPkKyOVg{ODd7PD;hQi=>
Bel7402 Ml3rR5l1d3SxeHnjbZR6KGG|c3H5 MX63NkBp MkTYTWM2OCB;IECuNFA3KM7:TR?= NHXUfXg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkW4N|A4QSd-MkK1PFMxPzl:L3G+
A549 NHjjdYtEgXSxdH;4bYNqfHliYYPzZZk> M{j0XFczKGh? MnTUTWM2OCB;IECuNFE3KM7:TR?= Mnz1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3OEOwO|koRjJ{NUizNFc6RC:jPh?=
HCT8 NETv[I9EgXSxdH;4bYNqfHliYYPzZZk> NH;GTWY4OiCq M1PFN2lEPTBiPTCwMlA2OSEQvF2= NVj2NFV1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1PFMxPzlpPkKyOVg{ODd7PD;hQi=>
MES-SA NVf3fJpXS3m2b4TvfIlkcXS7IHHzd4F6 M4DsXFk3KGh? MV7JR|UxKD1iMD6wNFQh|ryP M4K2RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUi3OVE6Lz5{MkW4O|UyQTxxYU6=
MESSA/DX5 NVfucnNLS3m2b4TvfIlkcXS7IHHzd4F6 NGL5UJQ6PiCq Mm[wTWM2OCB;IECuO|Uh|ryP M{TDSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUi3OVE6Lz5{MkW4O|UyQTxxYU6=
HCT116 NUi1eZhLS3m2b4TvfIlkcXS7IHHzd4F6 MlLaTWM2OCB;IECuNFUh|ryP MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjZ7MUG3PUc,OjJ4OUGxO|k9N2F-
SKBR3 MkTOR5l1d3SxeHnjbZR6KGG|c3H5 MkDPTWM2OCB;IECuNVEh|ryP NY\jXGpMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK2PVEyPzlpPkKyOlkyOTd7PD;hQi=>
SK-MEL-5 MmrBR5l1d3SxeHnjbZR6KGG|c3H5 MYLJR|UxKD1iMD6xOUDPxE1? MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjZ7MUG3PUc,OjJ4OUGxO|k9N2F-
SKOV3 Ml[zR5l1d3SxeHnjbZR6KGG|c3H5 NWn0NnBUUUN3MDC9JFAvPCEQvF2= NF\rZ|c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mk[5NVE4QSd-MkK2PVEyPzl:L3G+
MCF7 NWLYfHZzS3m2b4TvfIlkcXS7IHHzd4F6 M{XBN2lEPTBiPTCwMlkh|ryP MlywQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ4OUGxO|koRjJ{NkmxNVc6RC:jPh?=
PC3 MXvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NHOwbmo1QCCq NXOxVHhTUUN3MDC9JFAvODByNDFOwG0> M4naN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{izPVU1Lz5{Mke4N|k2PDxxYU6=
paclitaxel-resistant PC3-TxR NH24NZRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHLQVJI1QCCq MYLJR|UxKD1iMD6xPFgh|ryP NE\CdXk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mke4N|k2PCd-MkK3PFM6PTR:L3G+
MCF7 NHnQNItEgXSxdH;4bYNqfHliYYPzZZk> NXXKXZQ3OjRiaB?= MWTJR|UxKD1iMD6wNVUh|ryP MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjhzOEC4NUc,OjJ6MUiwPFE9N2F-
SKBR3 MlPGS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NW\nPHdwPDhiaB?= NX:2cJZ7UUN3MDC9JFAvODBzOTFOwG0> MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh3MEKxOEc,OjJ6NUCyNVQ9N2F-
HepG2 M3fNcGN6fG:2b4jpZ4l1gSCjc4PhfS=> MUK3NkBp NUDa[4tvUUN3MDC9JFAvODByNESg{txO MlLMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
MCF7 MWPDfZRwfG:6aXPpeJkh[XO|YYm= MmjhO|IhcA>? NVTENYlDUUN3MDC9JFAvODB|IN88US=> MYS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh5MUKxO{c,OjJ6N{GyNVc9N2F-
A375 MUHDfZRwfG:6aXPpeJkh[XO|YYm= Mn;xO|IhcA>? NECxc5VKSzVyIE2gNE4xODl{IN88US=> MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh5MUKxO{c,OjJ6N{GyNVc9N2F-
BxPC3 Mn76R5l1d3SxeHnjbZR6KGG|c3H5 NY\s[GZFPzJiaB?= M2TpWWlEPTBiPTCwMlA6KM7:TR?= M121[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OEexNlE4Lz5{Mki3NVIyPzxxYU6=
SMMC7721 NV;uNm9OS3m2b4TvfIlkcXS7IHHzd4F6 MVe3NkBp NVfUO|NWUUN3MDC9JFAvOTVizszN NH\6dIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mki3NVIyPyd-MkK4O|EzOTd:L3G+
PANC1 MXfDfZRwfG:6aXPpeJkh[XO|YYm= NWDM[FEyPzJiaB?= MmLQTWM2OCB;IECuNlYh|ryP MnP4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
A549 M{XIN2N6fG:2b4jpZ4l1gSCjc4PhfS=> MkfVO|IhcA>? MoDvTWM2OCB;IECuO|Ih|ryP M17yZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OEexNlE4Lz5{Mki3NVIyPzxxYU6=
AGS MmTCR5l1d3SxeHnjbZR6KGG|c3H5 MXK3NkBp MoizTWM2OCB;IEGuOkDPxE1? NXPWO4k5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4O|EzOTdpPkKyPFcyOjF5PD;hQi=>
NCI-H2126 NWfYWlVrS3m2b4TvfIlkcXS7IHHzd4F6 NVjvbWh[PzJiaB?= M3HSfmlEPTBiPTCyMlUh|ryP NV7UNWJqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4O|EzOTdpPkKyPFcyOjF5PD;hQi=>
MDA-MB-231 Mkm2R5l1d3SxeHnjbZR6KGG|c3H5 NWLQNWFJPzJiaB?= M4LtUmlEPTBiPTC1JO69VQ>? MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh5MUKxO{c,OjJ6N{GyNVc9N2F-
U87 NVTjWZdRS3m2b4TvfIlkcXS7IHHzd4F6 NFTTW3o4OiCq MUDJR|UxKD1iOD6xJO69VQ>? MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh5MUKxO{c,OjJ6N{GyNVc9N2F-
HELF MlniR5l1d3SxeHnjbZR6KGG|c3H5 M4DQZlI1KGh? MWnJR|UxKD1iNz6xOEDPxE1? NFPhPYc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmwNVQyOCd-MkK5NFE1OTB:L3G+
BGC MlXZR5l1d3SxeHnjbZR6KGG|c3H5 MYWyOEBp MkXmTWM2OCB;IEmuNlYh|ryP MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjlyMUSxNEc,OjJ7MEG0NVA9N2F-
HELF NEK3SodEgXSxdH;4bYNqfHliYYPzZZk> MofWNlQhcA>? NWP4RohHUUN3MDC9JFcvOTRizszN NXXreoxmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NlE6PjZpPkKyPVIyQTZ4PD;hQi=>
BGC MXXDfZRwfG:6aXPpeJkh[XO|YYm= MUiyOEBp MnTITWM2OCB;IEmuNlYh|ryP NEDOcIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmyNVk3Pid-MkK5NlE6PjZ:L3G+
DU145 NFe4Ro9EgXSxdH;4bYNqfHliYYPzZZk> NEDwUIc4OiCq MXvHTVUxKD1iMD6wNFI2PSEQvF2= M2\Vd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUOyN|E{Lz5{MkmzNlMyOzxxYU6=
KB M37oWWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFe3XHc4OiCq M1rjXGdKPTBiPTCwMlAxOjZ3IN88US=> M3P3c|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUOyN|E{Lz5{MkmzNlMyOzxxYU6=
A549 MmLRR5l1d3SxeHnjbZR6KGG|c3H5 NHrWNVk4OiCq MmHiS2k2OCB;IECuNFA1QDlizszN M3H4WFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUOyN|E{Lz5{MkmzNlMyOzxxYU6=
KBVIN NGDqe3REgXSxdH;4bYNqfHliYYPzZZk> MmO2O|IhcA>? NIDwTlhIUTVyIE2gNE46PDhizszN NWC4emdQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5N|I{OTNpPkKyPVMzOzF|PD;hQi=>
HL60 MXrDfZRwfG:6aXPpeJkh[XO|YYm= NVLJTGdMPzJiaB?= MXjJR|UxKD1iMD6wNFI5OiEQvF2= NWLyOGo1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5OVk2OThpPkKyPVU6PTF6PD;hQi=>
HeLa M2\JNmN6fG:2b4jpZ4l1gSCjc4PhfS=> MVK3NkBp MYjJR|UxKD1iMD6wNFI6OyEQvF2= Moj1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7NUm1NVgoRjJ{OUW5OVE5RC:jPh?=
U937 MmnRR5l1d3SxeHnjbZR6KGG|c3H5 M1n4NFczKGh? M4fZeGlEPTBiPTCwMlAxOzN5IN88US=> MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl3OUWxPEc,OjJ7NUm1NVg9N2F-
HeLa MV\DfZRwfG:6aXPpeJkh[XO|YYm= MlW4TWM2OCB;IEGg{txO M3LaZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MUCzNFk4Lz5{M{GwN|A6PzxxYU6=
A2780 MYDDfZRwfG:6aXPpeJkh[XO|YYm= M1zzU2lEPTBiPTCxMlEh|ryP M1\BVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MUCzNFk4Lz5{M{GwN|A6PzxxYU6=
A549 MV\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NVTzUow3PzJiaB?= NV7vcFhwUUN3MDC9JFAvODB5MjFOwG0> NXf6SGV1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxNVcyPzFpPkKzNVE4OTdzPD;hQi=>
taxol-resistant A549-T12 NHf4cIZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{HEe|czKGh? NI\OSGVKSzVyIE2gNE4xPzV{IN88US=> MmHQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzMUexO|EoRjJ|MUG3NVcyRC:jPh?=
IGROV1/Pt1 NWHFdIxNS3m2b4TvfIlkcXS7IHHzd4F6 MkfvO|IhcA>? MWHJR|UxKD1iMD6wNFIzKM7:TR?= NY\Ob2Z{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOFA{PThpPkKzNVQxOzV6PD;hQi=>
SKOV3 MnXQR5l1d3SxeHnjbZR6KGG|c3H5 MVK3NkBp MYXJR|UxKD1iMD6wNFI4KM7:TR?= NEP2PGY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G0NFM2QCd-MkOxOFA{PTh:L3G+
U2OS MojFR5l1d3SxeHnjbZR6KGG|c3H5 NFHzWZo4OiCq M1rYNWlEPTBiPTCwMlAxOzRizszN MojjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNECzOVgoRjJ|MUSwN|U5RC:jPh?=
PANC1 MVzDfZRwfG:6aXPpeJkh[XO|YYm= NH\pOm84OiCq NXLUO4c2UUN3MDC9JFAvODB3MjFOwG0> NVLUO5pnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOFA{PThpPkKzNVQxOzV6PD;hQi=>
MIAPaCa2 MY\DfZRwfG:6aXPpeJkh[XO|YYm= MkjsO|IhcA>? MWLJR|UxKD1iMD6wNFczKM7:TR?= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF2MEO1PEc,OjNzNECzOVg9N2F-
IGROV1 NXvrb|h3S3m2b4TvfIlkcXS7IHHzd4F6 NYHLXGN3PzJiaB?= MYrJR|UxKD1iMD6wNlMh|ryP NG\2fIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G0NFM2QCd-MkOxOFA{PTh:L3G+
MES-SA NV\kWXh3S3m2b4TvfIlkcXS7IHHzd4F6 MmjDTWM2OCB;IECuNFA{KM7:TR?= M{P3XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MUSxPVE3Lz5{M{G0NVkyPjxxYU6=
A2780 NXK4Z4V5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Mn7UNkBl[Xm| M4G4bWlEPTBiPTCwMlAzQCEQvF2= NHLSdpo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G0PVMxPCd-MkOxOFk{ODR:L3G+
MDA-MB-231 NFWxT2xEgXSxdH;4bYNqfHliYYPzZZk> MnXuO|IhcA>? MlLQTWM2OCB;IECuNFUzKM7:TR?= NHuyWYQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G1N|M6Pyd-MkOxOVM{QTd:L3G+
HepG2 NHHSPVVEgXSxdH;4bYNqfHliYYPzZZk> NIXPVXg4OiCq NX7NN3NvUUN3MDC9JFAvODV2IN88US=> NWHL[29PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOVM{QTdpPkKzNVU{Ozl5PD;hQi=>
A549 MojoR5l1d3SxeHnjbZR6KGG|c3H5 M4GydFczKGh? NHf0RmFKSzVyIE2gNE4xPTZizszN MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF3M{O5O{c,OjNzNUOzPVc9N2F-
NUGC3 NXXpc3BRT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVjHTVUxKD1iMD6wNkDPxE1? NXzTWGI{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOlc3OTRpPkKzNVY4PjF2PD;hQi=>
HONE1 NYDFbY5RT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NWHtNlNNT0l3MDC9JFAvODJizszN M3:4SFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MU[3OlE1Lz5{M{G2O|YyPDxxYU6=
NCI-H460 MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MV3HTVUxKD1iMD6wN{DPxE1? MoLEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNke2NVQoRjJ|MU[3OlE1RC:jPh?=
MCF7 NI\wWZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4e4cGdKPTBiPTCwMlA{KM7:TR?= MnSzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNke2NVQoRjJ|MU[3OlE1RC:jPh?=
A549 M1SxVGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MlSxS2k2OCB;IECuNFYh|ryP MliyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNke2NVQoRjJ|MU[3OlE1RC:jPh?=
HepG2 NETGRZVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH3qUFVIUTVyIE2gNE4yQCEQvF2= MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF4N{[xOEc,OjNzNke2NVQ9N2F-
HeLa M4PxSmN6fG:2b4jpZ4l1gSCjc4PhfS=> MUW5OkBp NXHGcppVUUN3MDC9JFAvODBzIN88US=> NYTsZpFpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxO|Y3OjhpPkKzNVc3PjJ6PD;hQi=>
SW780 NEnJO3REgXSxdH;4bYNqfHliYYPzZZk> MXm5OkBp MnP1TWM2OCB;IECuNFAyOSEQvF2= NUj4d25yRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxO|Y3OjhpPkKzNVc3PjJ6PD;hQi=>
MESSA NFnJeJVEgXSxdH;4bYNqfHliYYPzZZk> MUW3NkBp M{WxPGlEPTBiPTCwMlAxPCEQvF2= NXG1dYZ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyNVQ1PTJpPkKzNlE1PDV{PD;hQi=>
OVCAR8 NVXJfFRWS3m2b4TvfIlkcXS7IHHzd4F6 NIm4[nFKSzVyIE2gNE4xODVizszN M2X5UVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG0OFUzLz5{M{KxOFQ2OjxxYU6=
HeLa MofYR5l1d3SxeHnjbZR6KGG|c3H5 NF:5cIY1QCCq M4\X[2lEPTBiPTCwMlAxPSEQvF2= NXTXR21mRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyNVQ1PTJpPkKzNlE1PDV{PD;hQi=>
A549 MUnDfZRwfG:6aXPpeJkh[XO|YYm= MVW0PEBp NIO4O|JKSzVyIE2gNE4xODdizszN M4rDclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG0OFUzLz5{M{KxOFQ2OjxxYU6=
HT-29 MWrDfZRwfG:6aXPpeJkh[XO|YYm= MkHUOFghcA>? NFe1NZlKSzVyIE2gNE4xODhizszN NHvMUJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{KxOFQ2Oid-MkOyNVQ1PTJ:L3G+
HCT15 NIPsSm9EgXSxdH;4bYNqfHliYYPzZZk> Ml3GO|IhcA>? M2PjZWlEPTBiPTCwMlA6KM7:TR?= M4jIOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG0OFUzLz5{M{KxOFQ2OjxxYU6=
MESSA/DX5 NWHlS2xGS3m2b4TvfIlkcXS7IHHzd4F6 MmHCO|IhcA>? MlzaTWM2OCB;IEGuO|Y1KM7:TR?= MkXqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{MUS0OVIoRjJ|MkG0OFUzRC:jPh?=
NCI/ADR-RES NVm2ZWJSS3m2b4TvfIlkcXS7IHHzd4F6 NIj0bVNKSzVyIE2gN{4{KM7:TR?= NVnZfnRxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyNVQ1PTJpPkKzNlE1PDV{PD;hQi=>
DU145 NG\BWmRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M2H3NmdKPTBiPTCwMlAxPjVizszN NUn2[ppQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyO|QyOjNpPkKzNlc1OTJ|PD;hQi=>
KB MmrnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MkTwS2k2OCB;IECuNFA4PzdizszN NIXzcpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{K3OFEzOyd-MkOyO|QyOjN:L3G+
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MCF7 MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUX3b3FIPDhiaB?= NEfLToJIUTVyIE2gNE4xODVizszN M4jXXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{K3OFY1Lz5{NEeyO|Q3PDxxYU6=
UACC62 M4q1b2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2TWTlQ5KGh? Mk\DS2k2OCB;IECuNFEh|ryP M17EbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{K3OFY1Lz5{NEeyO|Q3PDxxYU6=
786-0 NHTXZ|ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NEmyXno1QCCq NU\PN2FnT0l3MDC9JFAvODJizszN NF;JVJk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEeyO|Q3PCd-MkS3Nlc1PjR:L3G+
African green monkey Vero M37wdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGjOZZo1QCCq NIjXNmZIUTVyIE2gNE4xOyEQvF2= NX\yWGJPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3Nlc1PjRpPkK0O|I4PDZ2PD;hQi=>
NCI-ADR-RES MXPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHTRNmM1QCCq NV\TSodqT0l3MDC9JFAvODRizszN MkHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5Mke0OlQoRjJ2N{K3OFY1RC:jPh?=
NCI-H460 M1TQOmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NXvJRmlxPDhiaB?= NH\SV4JIUTVyIE2gNE4yKM7:TR?= MnrWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5Mke0OlQoRjJ2N{K3OFY1RC:jPh?=
PC3 MUPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWi0PEBp MlPTS2k2OCB;IECuNUDPxE1? MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd{N{S2OEc,OjR5Mke0OlQ9N2F-
K562 MUXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NG\WN5o1QCCq MXPHTVUxKD1iMD6xJO69VQ>? M2T5blxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{K3OFY1Lz5{NEeyO|Q3PDxxYU6=
OVCAR3 M4H3TGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mn\iOFghcA>? MULHTVUxKD1iMD6yJO69VQ>? NHHsT4E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEeyO|Q3PCd-MkS3Nlc1PjR:L3G+
HepG2 NVrMVJp2S3m2b4TvfIlkcXS7IHHzd4F6 MWizJIRigXN? NITvVZlKSzVyIE2gNE4xODBzOTFOwG0> MofHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5NEW5OlgoRjJ2N{S1PVY5RC:jPh?=
KB M{HGc2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoXqN{Bl[Xm| MYfJR|UxKD1iMD6wNFM6KM7:TR?= M{f5VlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{S1PVY5Lz5{NEe0OVk3QDxxYU6=
NCI-ADR-RES MXzDfZRwfG:6aXPpeJkh[XO|YYm= NWj6OGpJTUN3MDC9JFAvODF|IN88US=> NUDmUnpERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS4NFE3OTBpPkK0PFAyPjFyPD;hQi=>
OVCAR8 MWrDfZRwfG:6aXPpeJkh[XO|YYm= MkCzSWM2OCB;IECuNFE5KM7:TR?= Mnv4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6MEG2NVAoRjJ2OECxOlExRC:jPh?=
NALM6 M3LOWmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NVX3OpA5PDhidH:gO|IhcA>? MWXJR|UxKD1iMD6wNFQyKM7:TR?= MlrnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6NUKyPFEoRjJ2OEWyNlgyRC:jPh?=
Jurkat Mn\BRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M4PyW|Q5KHSxIEeyJIg> Mn;KTWM2OCB;IECuNFA1PSEQvF2= NGDtfHU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi1NlI5OSd-MkS4OVIzQDF:L3G+
K562 M3W0b2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MVi0PEB1dyB5MjDo NX2wcJBDUUN3MDC9JFAvODB3NTFOwG0> NGHFXlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi1NlI5OSd-MkS4OVIzQDF:L3G+
HeLa NWXIU493SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3vTTmlEPTBiPTCwMlAxOTJzIN88US=> MlnnQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6OUC2OVIoRjJ2OEmwOlUzRC:jPh?=
MDA-MB-435 NY\H[INzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MlHxTWM2OCB;IECuNFAyQTNizszN NGewelA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi5NFY2Oid-MkS4PVA3PTJ:L3G+
SKOV3 NUXMbVR1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3H5bGlEPTBiPTCwMlAxOyEQvF2= NIHqOIE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi5NFY2Oid-MkS4PVA3PTJ:L3G+
SKOV3 NY\4TGZ6S3m2b4TvfIlkcXS7IHHzd4F6 MW\HTVUxKD1iMD6wNFQ4KM7:TR?= NVL6SnR7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS4PVMzOjRpPkK0PFk{OjJ2PD;hQi=>
P-gp expressing SKOV3-M6/6 MXTDfZRwfG:6aXPpeJkh[XO|YYm= NHHQ[HhIUTVyIE2gNE43KM7:TR?= M4HESVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OEmzNlI1Lz5{NEi5N|IzPDxxYU6=
PC3 NUfRR2RFS3m2b4TvfIlkcXS7IHHzd4F6 MWS5OkBp NWjoSmRYUUN3MDC9JFAvODB{NTFOwG0> MlH4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MEC0N|coRjJ2OUCwOFM4RC:jPh?=
HeLa M3vHRmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWG5OkBp MkGxTWM2OCB;IECuNFA2OyEQvF2= MmTTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MEC4OlUoRjJ2OUCwPFY2RC:jPh?=
OVCAR8 MlvCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHrZS3Y6PiCq MorITWM2OCB;IECuNFEh|ryP MkLpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MEC4OlUoRjJ2OUCwPFY2RC:jPh?=
NCI/ADR-RES MX;Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MVG5OkBp Mn\qTWM2OCB;IEWg{txO NEXifFQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEmwNFg3PSd-MkS5NFA5PjV:L3G+
MCF7 M3TaeGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4LLW|czKGh? NYPQTYpkUUN3MDC9JFAvODR3IN88US=> MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl{OUO0OEc,OjR7MkmzOFQ9N2F-
HCT116 MnXsR5l1d3SxeHnjbZR6KGG|c3H5 M4nTXFczKGh? Mn[5TWM2OCB;IECuNFY6KM7:TR?= MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl{OUO0OEc,OjR7MkmzOFQ9N2F-
HepG2 NXfhTlk4S3m2b4TvfIlkcXS7IHHzd4F6 Mm\sO|IhcA>? NFKxfHJKSzVyIE2gNE4xQDRizszN M3:4W|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUK5N|Q1Lz5{NEmyPVM1PDxxYU6=
HeLa MYDDfZRwfG:6aXPpeJkh[XO|YYm= NXfkUnNzPzJiaB?= MmnYTWM2OCB;IECuNFk3KM7:TR?= NVLW[moyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5Nlk{PDRpPkK0PVI6OzR2PD;hQi=>
U251 MmnDR5l1d3SxeHnjbZR6KGG|c3H5 NEW3T|c4OiCq M1:2W2lEPTBiPTCwMlEzQCEQvF2= NYfGRotWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5Nlk{PDRpPkK0PVI6OzR2PD;hQi=>
HT-29 MmrkR5l1d3SxeHnjbZR6KGG|c3H5 MmXhTWM2OCB;IECuNFAyKM7:TR?= NUDud5pPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5N|czODlpPkK0PVM4OjB7PD;hQi=>
HT-29 NH7ydmpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MkT4NlQh[W6mIEeyJIg> Ml62TWM2OCB;IECuNlkh|ryP MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl2MUGzNEc,OjR7NEGxN|A9N2F-
HeLa MVjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MWiyOEBidmRiN{KgbC=> NIPwcHpKSzVyIE2gNE4zQSEQvF2= MkL6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7NEGxN|AoRjJ2OUSxNVMxRC:jPh?=
Caco2 NHf4WmJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MkfFNlQh[W6mIEeyJIg> MV7JR|UxKD1iMD6zNUDPxE1? MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl2MUGzNEc,OjR7NEGxN|A9N2F-
HL60 MVLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MmnQNlQh[W6mIEeyJIg> MYTJR|UxKD1iMD6zNkDPxE1? MmLaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7NEGxN|AoRjJ2OUSxNVMxRC:jPh?=
MCF7 NG\1flRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NUfIO|dVOjRiYX7kJFczKGh? NYPRNWs1UUN3MDC9JFAvOzNizszN NIWzNHM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm0NVE{OCd-MkS5OFEyOzB:L3G+
Saos2 MWDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NUDoR5NNOjRiYX7kJFczKGh? NXrQR2R4UUN3MDC9JFAvOzVizszN NYXrdGkxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OFEyOzBpPkK0PVQyOTNyPD;hQi=>
SKOV3-MDR1-M6/6 NUfCN5ZFSW62aXPhcoNmeiCjc4PhfS=> NIDEXYI1QCCq MYTJR|UxKD1iMD65O{DPxE1? NEfJeHY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm0OlE1PSd-MkS5OFYyPDV:L3G+
SKOV3 M4HWemFvfGmlYX7j[ZIh[XO|YYm= NETBOXE1QCCq NXnDOI9[UUN3MDC9JFEh|ryP M1nXWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUS2NVQ2Lz5{NEm0OlE1PTxxYU6=
MDA435/LCC6 MXTDfZRwfG:6aXPpeJkh[XO|YYm= M1[5V|Uh\GG7cx?= NUi0XJkyUUN3MDC9JFAvODB{NjFOwG0> NVi3[2d4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OVI{PzZpPkK0PVUzOzd4PD;hQi=>
MDA435/LCC6MDR M{DmZmN6fG:2b4jpZ4l1gSCjc4PhfS=> MmrJOUBl[Xm| NH35d3BKSzVyIE2gNE4yPDl|IN88US=> NUPvN2NwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OVI{PzZpPkK0PVUzOzd4PD;hQi=>
MCF7 NVvXOmVjS3m2b4TvfIlkcXS7IHHzd4F6 NW\SR3lFUUN3MDC9JFAvODBzNTFOwG0> NVjw[nd5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OlAyPDNpPkK0PVYxOTR|PD;hQi=>
HepG2 NEK5PGtEgXSxdH;4bYNqfHliYYPzZZk> MoT5TWM2OCB;IECuNFA1PiEQvF2= MnjBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7NkCxOFMoRjJ2OU[wNVQ{RC:jPh?=
MDA-MB-231 MXfDfZRwfG:6aXPpeJkh[XO|YYm= MWHJR|UxKD1iMD6wNFgzKM7:TR?= M3viTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OU[wNVQ{Lz5{NEm2NFE1OzxxYU6=
HL7702 NWrTXHVyS3m2b4TvfIlkcXS7IHHzd4F6 MUHJR|UxKD1iMT6xJO69VQ>? NF;qb3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm2NFE1Oyd-MkS5OlAyPDN:L3G+
MCF7 NIT6TWxCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= Mm[0OFghcA>? M1XoS2lEPTBiPTCwMlAzPThzIN88US=> NYjmVJk2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5PVYyOzZpPkK0PVk3OTN4PD;hQi=>
HepG2 MnjyRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NFfmVFA1QCCq NYfz[ppvUUN3MDC9JFAvODZ5Mkeg{txO MmS4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7OU[xN|YoRjJ2OUm2NVM3RC:jPh?=
A549 NVPvdHR{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NV7nTGd2PDhiaB?= NHW2eWlKSzVyIE2gNU42OjVizszN NEnFTYU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm5OlE{Pid-MkS5PVYyOzZ:L3G+
KB NFHadXFEgXSxdH;4bYNqfHliYYPzZZk> MnnVO|IhcA>? MYfJR|UxKD1iMD6wNFM6KM7:TR?= MmDiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyMEi0OVYoRjJ3MEC4OFU3RC:jPh?=
A549 M{fiS2N6fG:2b4jpZ4l1gSCjc4PhfS=> NGO5SnE4OiCq MkfQTWM2OCB;IECuNFA2PyEQvF2= Mnm5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyMEi0OVYoRjJ3MEC4OFU3RC:jPh?=
MDA-MB-231 M3zvT2N6fG:2b4jpZ4l1gSCjc4PhfS=> MV23NkBp NWCyfFB6UUN3MDC9JFAvODB4NjFOwG0> NHXLUG89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUCwPFQ2Pid-MkWwNFg1PTZ:L3G+
KBVIN NVnub5FVS3m2b4TvfIlkcXS7IHHzd4F6 NGfjPHE4OiCq NFzzUFdKSzVyIE2gNU41PCEQvF2= NXPpd4tGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFg1PTZpPkK1NFA5PDV4PD;hQi=>
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OVCAR8 MnviR5l1d3SxeHnjbZR6KGG|c3H5 NY\WUpRHQTZiaB?= NYjlT5M4UUN3MDC9JFAvODB3IN88US=> NH7wUY89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUCyOVk6OSd-MkWwNlU6QTF:L3G+
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A2780 MmPXR5l1d3SxeHnjbZR6KGG|c3H5 MonoTWM2OCB;IECuNFAxPCEQvF2= MoLqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNEe5N|goRjJ3MES3PVM5RC:jPh?=
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MCF7 NGHXU|REgXSxdH;4bYNqfHliYYPzZZk> NVjBPIJvUUN3MDC9JFAvODBzNzFOwG0> M1vDU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MES3PVM5Lz5{NUC0O|k{QDxxYU6=
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1A9PTX10 Mmm1R5l1d3SxeHnjbZR6KGG|c3H5 M1WzT2lEPTBiPTCwMlA5OTRizszN NWjXfItlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwOFc6OzhpPkK1NFQ4QTN6PD;hQi=>
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HCT8 MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NHfpPVE1QCCq MoPRTWM2OCB;IECuNFIyKM7:TR?= M1S1RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3ME[xPFA{Lz5{NUC2NVgxOzxxYU6=
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HL60 MWrDfZRwfG:6aXPpeJkh[XO|YYm= MkH1OFghcA>? MkTETWM2OCB;IEGuOUDPxE1? NFrTcGY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUKxNVA{Oid-MkWyNVExOzJ:L3G+
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A549 M37FNGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVPWcFhGOjRiaB?= MXfJR|UxKD1iMT6wOEDPxE1? M4nzZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkK2N|Y{Lz5{NUKyOlM3OzxxYU6=
DU145 MXLDfZRwfG:6aXPpeJkh[XO|YYm= MVSyOEBp MnvxTWM2OCB;IEGuO|kh|ryP NYT1V|FIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyNlY{PjNpPkK1NlI3OzZ|PD;hQi=>
A549 MYHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MUCzJIRigXN? MX\JR|UxKD1iMD6wNFI1KM7:TR?= NVf3RnhJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyOFE6OjVpPkK1NlQyQTJ3PD;hQi=>
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DU145 MUfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MWCzJIRigXN? NYSyc4ZYUUN3MDC9JFAvODB2OEig{txO M4\RUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkSxPVI2Lz5{NUK0NVkzPTxxYU6=
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MDA-MB-231 M3;FSWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NIW1ZWc1QCCq M1PCPGdKPTBiPTCwMlA6OSEQvF2= MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTJ4NEC3Nkc,OjV{NkSwO|I9N2F-
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HL60 M{PkOmN6fG:2b4jpZ4l1gSCjc4PhfS=> MnvjOFghcA>? NUeyfldNUUN3MDC9JFAvODB6IN88US=> MmfDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV|N{WyNFIoRjJ3M{e1NlAzRC:jPh?=
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SW480 MkHOR5l1d3SxeHnjbZR6KGG|c3H5 M4\PZVQ5KGh? NWCzNpJSUUN3MDC9JFAvOTVizszN MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTN5NUKwNkc,OjV|N{WyNFI9N2F-
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MDA-MB-231 NYr5bo9ESW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MVi0JIg> NV:4PZpiUUN3MDC9JFYvOiEQvF2= NF\jfpM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUS1N|c6QCd-MkW0OVM4QTh:L3G+
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SMMC7721 MWLBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MkW3O|IhcA>? M3fZUGlEPTBiPTCwMlEzKM7:TR?= Mo\IQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV5N{G0PFQoRjJ3N{exOFg1RC:jPh?=
SMMC7721 NInTSFNEgXSxdH;4bYNqfHliYYPzZZk> M2LZc|Q5KGh? NInvfpVKSzVyIE2gNE4xODhizszN M13zNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3N{m4OVI5Lz5{NUe5PFUzQDxxYU6=
HL60 MVnDfZRwfG:6aXPpeJkh[XO|YYm= MV20PEBp M2Sze2lEPTBiPTCwMlAxQCEQvF2= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTd7OEWyPEc,OjV5OUi1Nlg9N2F-
A549 Mn\rR5l1d3SxeHnjbZR6KGG|c3H5 NVr4TFNrPDhiaB?= M1;4TGlEPTBiPTCwMlAxQCEQvF2= MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTd7OEWyPEc,OjV5OUi1Nlg9N2F-
MCF7 Mk\NR5l1d3SxeHnjbZR6KGG|c3H5 M{fTV|Q5KGh? NUHncXpNUUN3MDC9JFAvODB6IN88US=> NYqybFhtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW3PVg2OjhpPkK1O|k5PTJ6PD;hQi=>
SW480 M1HsW2N6fG:2b4jpZ4l1gSCjc4PhfS=> NULIUVNqPDhiaB?= NWn3XI1MUUN3MDC9JFAvODB6IN88US=> NGDLcZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUe5PFUzQCd-MkW3PVg2Ojh:L3G+
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MOLT4 NIG5NYpEgXSxdH;4bYNqfHliYYPzZZk> NHX2dGI4OiCq NYrHR4l3UUN3MDC9JFAvODB{MjFOwG0> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPThzOUC5Okc,OjV6MUmwPVY9N2F-
U937 NVnVNm5PS3m2b4TvfIlkcXS7IHHzd4F6 M1HydFczKGh? MkixTWM2OCB;IECuNFAzPSEQvF2= MmruQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUmwPVYoRjJ3OEG5NFk3RC:jPh?=
HeLa MW\DfZRwfG:6aXPpeJkh[XO|YYm= MVu3NkBp M4WzWGlEPTBiPTCwMlAxOzJizszN MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPThzOUC5Okc,OjV6MUmwPVY9N2F-
DU145 MVzDfZRwfG:6aXPpeJkh[XO|YYm= M1zhW|czKGh? NF3BRYNKSzVyIE2gNE4xODN2IN88US=> MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPThzOUC5Okc,OjV6MUmwPVY9N2F-
A549 NUTHZ4hMS3m2b4TvfIlkcXS7IHHzd4F6 NYHpeVJQPzJiaB?= NHvlfIlKSzVyIE2gNE4xODR2IN88US=> NFq3N2s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUixPVA6Pid-MkW4NVkxQTZ:L3G+
SGC7901 MY\DfZRwfG:6aXPpeJkh[XO|YYm= NEDVUY44OiCq NUO5PWFZUUN3MDC9JFAvODB3MTFOwG0> M2jDcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEG5NFk3Lz5{NUixPVA6PjxxYU6=
K562 NUDWO4hCS3m2b4TvfIlkcXS7IHHzd4F6 MVe3NkBp MYXJR|UxKD1iMD6wNFUzKM7:TR?= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPThzOUC5Okc,OjV6MUmwPVY9N2F-
MCF7 MXfDfZRwfG:6aXPpeJkh[XO|YYm= M{nEd|czKGh? MWHJR|UxKD1iMD6wNFYzKM7:TR?= MlrQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUmwPVYoRjJ3OEG5NFk3RC:jPh?=
NCI-H1975 Mm\0R5l1d3SxeHnjbZR6KGG|c3H5 NGrLUHQ4OiCq NWXhdoxQUUN3MDC9JFAvODB5NzFOwG0> M2PpR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEG5NFk3Lz5{NUixPVA6PjxxYU6=
MX1 MV7DfZRwfG:6aXPpeJkh[XO|YYm= M3:0NlczKGh? NFy3U2lKSzVyIE2gNE4xODV3OTFOwG0> NIXabW09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUixPVM{PCd-MkW4NVk{OzR:L3G+
ID8 MY\DfZRwfG:6aXPpeJkh[XO|YYm= MXO3NkBp NELES4pKSzVyIE2gNE4xOTN6IN88US=> NU[zZZFPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVk{OzRpPkK1PFE6OzN2PD;hQi=>
L1210 Ml2xR5l1d3SxeHnjbZR6KGG|c3H5 NULySpJwPzJiaB?= Mn3uTWM2OCB;IECuNFI4PiEQvF2= NWfqcFRoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVk{OzRpPkK1PFE6OzN2PD;hQi=>
WI38 NYCxPWtSS3m2b4TvfIlkcXS7IHHzd4F6 MVG3NkBp MXrJR|UxKD1iMD6wOVU4KM7:TR?= M4LwU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEG5N|M1Lz5{NUixPVM{PDxxYU6=
MDA-MB-231 Mn3rRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M3v6[|Q5KGh? NETuXHVIUTVyIE2gNE4xOSEQvF2= NHXRfnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUiyO|UzOid-MkW4Nlc2OjJ:L3G+
A549 MnfRRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Moi0OFghcA>? NUnTeGhPT0l3MDC9JFAvODFizszN M4K1SFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEK3OVIzLz5{NUiyO|UzOjxxYU6=
PANC1 Ml\kRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MkPrOFghcA>? NUHkdYxFT0l3MDC9JFAvODF{IN88US=> M1LxUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEK3OVIzLz5{NUiyO|UzOjxxYU6=
HeLa NUjkTJdQSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NGrRRmI1QCCq MXrHTVUxKD1iMD6wNkDPxE1? M2j0dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEK3OVIzLz5{NUiyO|UzOjxxYU6=
HEK293 MY\DfZRwfG:6aXPpeJkh[XO|YYm= MWO3NkBp MV;JR|UxKD1iMD6wOEDPxE1? NV\vPXBQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4OFI{PjRpPkK1PFQzOzZ2PD;hQi=>
SW480 MUPDfZRwfG:6aXPpeJkh[XO|YYm= MlT4OFghcA>? M{TXSmlEPTBiPTCwMlAxQCEQvF2= Mk[yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6N{GyOlEoRjJ3OEexNlYyRC:jPh?=
HL60 NWLSXFdmS3m2b4TvfIlkcXS7IHHzd4F6 MV:0PEBp NVq4NoU2UUN3MDC9JFAvODB6IN88US=> Mk\MQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6N{GyOlEoRjJ3OEexNlYyRC:jPh?=
MCF7 NXP0T5RmS3m2b4TvfIlkcXS7IHHzd4F6 NU[3W3FRPDhiaB?= M4S0e2lEPTBiPTCwMlAxQCEQvF2= M4C5WFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEexNlYyLz5{NUi3NVI3OTxxYU6=
SMMC7721 MXPDfZRwfG:6aXPpeJkh[XO|YYm= NFfKfms1QCCq NEnMeItKSzVyIE2gNE4xODhizszN NH;IPGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi3NVI3OSd-MkW4O|EzPjF:L3G+
A549 NY\6NZNKS3m2b4TvfIlkcXS7IHHzd4F6 NFLEZnM1QCCq NGruXo1KSzVyIE2gNE4xODhizszN NFjWV5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi3NVI3OSd-MkW4O|EzPjF:L3G+
SCC114 MUXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NXTIfVlQPzJiaB?= Mn3mTWM2OCB;IECuNFAxOyEQvF2= NF\JWXo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi3Nlk5PCd-MkW4O|I6QDR:L3G+
HeLa MoP2RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Ml61OFghcA>? MUXJR|UxKD1iMD6wNFE6KM7:TR?= NWH1PYdtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4PFI2OTlpPkK1PFgzPTF7PD;hQi=>
MDA-MB-435 NGTpNW5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NUSycnp5PDhiaB?= MWjJR|UxKD1iMD6wNFM{KM7:TR?= M1u5VFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEiyOVE6Lz5{NUi4NlUyQTxxYU6=
SKOV3 NF3tVXpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NXn0SoNDPDhiaB?= M2W2bWlEPTBiPTCwMlAxPjNizszN MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh6MkWxPUc,OjV6OEK1NVk9N2F-
SKOV3-MDR1-M6/6 M4WwWGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MYe0PEBp NI[xfW1KSzVyIE2gNU4yQDd{IN88US=> NFTMPHM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi4NlUyQSd-MkW4PFI2OTl:L3G+
A549 MVvBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MYe0PEBp M37qR2lEPTBiPTCwMlAxOjNizszN M3zu[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUO3NlM3Lz5{NUmzO|I{PjxxYU6=
taxol-resistant A549 NFPvcJVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NX[xbFI5PDhiaB?= Mn7KTWM2OCB;IECuOVIh|ryP MlfWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7M{eyN|YoRjJ3OUO3NlM3RC:jPh?=
EL4 MWPDfZRwfG:6aXPpeJkh[XO|YYm= M{OxdVQ5KGh? M4H1SWlEPTBiPTCxMlch|ryP MknEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7NUGwOVcoRjJ3OUWxNFU4RC:jPh?=
HeLa M4C3XGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M2i5[FQ5KGh? MnjlTWM2OCB;IECuN|gh|ryP NH\S[Gc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm1PVgyOyd-MkW5OVk5OTN:L3G+
A549 NG\FNodCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NIK1R2k1QCCq M3H4NWlEPTBiPTCyMlgzKM7:TR?= MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTl3OUixN{c,OjV7NUm4NVM9N2F-
LCC-6 NVHmZ21vS3m2b4TvfIlkcXS7IHHzd4F6 MYGzJIRigXN? NYD5XVZ6UUN3MDC9JFAvODBzNjFOwG0> NXPre4w3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW5PFUyQTVpPkK1PVg2OTl3PD;hQi=>
MDA435/LCC6MDR MnTyR5l1d3SxeHnjbZR6KGG|c3H5 MkPqN{Bl[Xm| M3\XcmlEPTBiPTCwMlE1PDZizszN MmDYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7OEWxPVUoRjJ3OUi1NVk2RC:jPh?=
A2780 M1\EZWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MYGyJIRigXN? MVrJR|UxKD1iMD6wNlgh|ryP MlPvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZyNEK0O|AoRjJ4MESyOFcxRC:jPh?=
SMMC7721 NWLt[YlES3m2b4TvfIlkcXS7IHHzd4F6 NGnoemU1QCCq MU\JR|UxKD1iMD6wNFgh|ryP NI\Yc2g9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkC2PFgxOid-Mk[wOlg5ODJ:L3G+
HL60 M2LJOWN6fG:2b4jpZ4l1gSCjc4PhfS=> MomxOFghcA>? MVzJR|UxKD1iMD6wNFgh|ryP NGrEfXI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkC2PFgxOid-Mk[wOlg5ODJ:L3G+
MCF7 NGW1[5VEgXSxdH;4bYNqfHliYYPzZZk> MlTOOFghcA>? NWLLZZZWUUN3MDC9JFAvODB6IN88US=> M2HKbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4ME[4PFAzLz5{NkC2PFgxOjxxYU6=
A549 NXvFcYo1S3m2b4TvfIlkcXS7IHHzd4F6 NVTCR5Z6PDhiaB?= MX;JR|UxKD1iMD6wNFgh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjB4OEiwNkc,OjZyNki4NFI9N2F-
SW480 MVjDfZRwfG:6aXPpeJkh[XO|YYm= Mk[4OFghcA>? MmXqTWM2OCB;IECuNFA5KM7:TR?= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjB4OEiwNkc,OjZyNki4NFI9N2F-
BEAS2B MX\DfZRwfG:6aXPpeJkh[XO|YYm= MWS0PEBp Mn:yTWM2OCB;IECuOVgh|ryP MoPUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZyNki4NFIoRjJ4ME[4PFAzRC:jPh?=
NB4 MX3DfZRwfG:6aXPpeJkh[XO|YYm= NEK3Xlg1QCCq NIjtZWpKSzVyIE2gNE4xODJ|IN88US=> NYHXbWlwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
NCI-H1975 MV\DfZRwfG:6aXPpeJkh[XO|YYm= MljXO|IhcA>? NIn3VXlKSzVyIE2gNE4xODJ3IN88US=> M4nKRVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
OVCAR8 M1XDSmN6fG:2b4jpZ4l1gSCjc4PhfS=> NILvTHo1QCCq NH3WWGhKSzVyIE2gNE4xODN5IN88US=> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjF|MkC3OUc,OjZzM{KwO|U9N2F-
MESSA M{nvVGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGLxdG84OiCq Mm\1TWM2OCB;IECuNFA1KM7:TR?= M1TXXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
MDA-MB-468 NFnpNI5EgXSxdH;4bYNqfHliYYPzZZk> NGf6N4g4OiCq MVjJR|UxKD1iMD6wNFUh|ryP NHPkZVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
A549 NHPXTWZEgXSxdH;4bYNqfHliYYPzZZk> MXq3NkBp MU\JR|UxKD1iMD6wNFch|ryP NXXEUWd1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
MDA-MB-231 MYjDfZRwfG:6aXPpeJkh[XO|YYm= NEHWWmw4OiCq NFfZNJhKSzVyIE2gNE4xODdizszN NWL1NZU{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
MDA-MB-436 MmDRR5l1d3SxeHnjbZR6KGG|c3H5 MY[3NkBp MYrJR|UxKD1iMD6wNFgh|ryP NHHsboE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
MESSA/DX5 NH63UWhEgXSxdH;4bYNqfHliYYPzZZk> MV:3NkBp M3vBNWlEPTBiPTCxMlc3PCEQvF2= NHXucoM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
HepG2 MlHXR5l1d3SxeHnjbZR6KGG|c3H5 M3;6UFQ5KGh? NELpW3BKSzVyIE2gNk43KM7:TR?= M33nb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
PC3 M2C1eWN6fG:2b4jpZ4l1gSCjc4PhfS=> NVLWOHBWPDhiaB?= MX\JR|UxKD1iND65JO69VQ>? NGm2PZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
NCI-ADR-RES MYrDfZRwfG:6aXPpeJkh[XO|YYm= MmnQOFghcA>? NV3KZ3ZDUUN3MDC9JFYh|ryP NH;GT5I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
KB MmXDRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NFjwcXA4OiCq NHHjbo9KSzVyIE2gNE4xODVzIN88US=> NXPrPWZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xOlAxOjBpPkK2NVYxODJyPD;hQi=>
KB-7d M2fZOmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MnvnO|IhcA>? MkLWTWM2OCB;IECuNFA5PCEQvF2= MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjF4MECyNEc,OjZzNkCwNlA9N2F-
KB-S15 NHrFd|NCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MWi3NkBp MV;JR|UxKD1iMD6xN|Uh|ryP NFfiZZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkG2NFAzOCd-Mk[xOlAxOjB:L3G+
DU145 Mk\XRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NFfQWotIUTVyIE2gNE4xODZizszN NWjPZ|BvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yOFIzPDJpPkK2NlQzOjR{PD;hQi=>
KB NYe5VVJPSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWi2RoI3T0l3MDC9JFAvODB4NDFOwG0> NWf5UZd1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yOFIzPDJpPkK2NlQzOjR{PD;hQi=>
A549 M2G5d2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NHHl[VZIUTVyIE2gNE4xODd4IN88US=> M1nTU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MkSyNlQzLz5{NkK0NlI1OjxxYU6=
vincristine-resistant KBVIN NXKzUY9QSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MXLHTVUxKD1iMT6yNUDPxE1? MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ2MkK0Nkc,OjZ{NEKyOFI9N2F-
K562 MWHDfZRwfG:6aXPpeJkh[XO|YYm= MXjJR|UxKD1iMD65JO69VQ>? M3zKOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4Mki3OFAyLz5{NkK4O|QxOTxxYU6=
U937 MXjDfZRwfG:6aXPpeJkh[XO|YYm= NUHOcFVNPzJiaB?= MVPJR|UxKD1iMj6xJO69VQ>? NGXIbIE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
A549 NWfJVmdQS3m2b4TvfIlkcXS7IHHzd4F6 M4C5cFczKGh? Ml3aTWM2OCB;IEKuNUDPxE1? NEnrNXM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
MCF7 MVLDfZRwfG:6aXPpeJkh[XO|YYm= MXK3NkBp M4DHSmlEPTBiPTCyMlMh|ryP NFO3[Yo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
MOLT4 NFjwVpJEgXSxdH;4bYNqfHliYYPzZZk> MWO3NkBp MWPJR|UxKD1iMj63JO69VQ>? NHn3[lM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
NCI-H1975 NEfycVBEgXSxdH;4bYNqfHliYYPzZZk> MkDRO|IhcA>? MlLxTWM2OCB;IEKuPEDPxE1? MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNzNkS2O{c,OjZ|MU[0Olc9N2F-
HeLa Ml\yR5l1d3SxeHnjbZR6KGG|c3H5 MYC3NkBp MWTJR|UxKD1iMj65JO69VQ>? M17CelxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{G2OFY4Lz5{NkOxOlQ3PzxxYU6=
DU145 MVfDfZRwfG:6aXPpeJkh[XO|YYm= M4K2b|czKGh? NUHjepU2UUN3MDC9JFMvOSEQvF2= MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNzNkS2O{c,OjZ|MU[0Olc9N2F-
K562 NWH5d3B2S3m2b4TvfIlkcXS7IHHzd4F6 NV3rW5RsPzJiaB?= Ml72TWM2OCB;IEOuPEDPxE1? NH\BNWQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
HL60 NXjreJh3S3m2b4TvfIlkcXS7IHHzd4F6 M1XRSVczKGh? MUnJR|UxKD1iMz64JO69VQ>? M{P1[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{G2OFY4Lz5{NkOxOlQ3PzxxYU6=
SGC7901 Mo\tR5l1d3SxeHnjbZR6KGG|c3H5 NGrTOWw4OiCq NVjNS4pGUUN3MDC9JFkvQCEQvF2= NX\iXGRqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[zNVY1PjdpPkK2N|E3PDZ5PD;hQi=>
MES-SA Mo\CR5l1d3SxeHnjbZR6KGG|c3H5 M4\BUVQ5KGh? M3yxdGdKPTBiPTCwMlAxPyEQvF2= M13HcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{[wNFQ4Lz5{NkO2NFA1PzxxYU6=
Rhabdomyosarcoma Ml;SRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Mn;IPVYhcA>? NUXhflBbUUN3MDC9JFAvODB6NDFOwG0> MmPMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ|OE[4NVgoRjJ4M{i2PFE5RC:jPh?=
HT-29 MVzDfZRwfG:6aXPpeJkh[XO|YYm= Mn:2N{Bl[Xm| NFT2bZFKSzVyIE2gNE4xODB6IN88US=> NEXxb4M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkSyNlE{OSd-Mk[0NlIyOzF:L3G+
MDA-MB-231 NX7TZYdOS3m2b4TvfIlkcXS7IHHzd4F6 M1nQO|czKGh? MnjpTWM2OCB;IECuNFAyKM7:TR?= M{DFblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NES4NFM4Lz5{NkS0PFA{PzxxYU6=
PC3 MXfDfZRwfG:6aXPpeJkh[XO|YYm= NUfEXmxUPzJiaB?= MoPETWM2OCB;IECuNFAyKM7:TR?= NIXVeo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkS0PFA{Pyd-Mk[0OFgxOzd:L3G+
HCT116 Mn7sR5l1d3SxeHnjbZR6KGG|c3H5 NUjXdWtbPDhiaB?= NH;IdppKSzVyIE2gNE4xODJ6IN88US=> M13LeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NES4NFM4Lz5{NkS0PFA{PzxxYU6=
A549 NVH1TolZS3m2b4TvfIlkcXS7IHHzd4F6 MV\JR|UxKD1iMD6wNFY{KM7:TR?= M3vTOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NES4NFM4Lz5{NkS0PFA{PzxxYU6=
HepG2 MoL4R5l1d3SxeHnjbZR6KGG|c3H5 MWC0PEBp NHPPXJZKSzVyIE2gNU4zOTdizszN Mn7BQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ2NEiwN|coRjJ4NES4NFM4RC:jPh?=
H460 NYLmbXB6S3m2b4TvfIlkcXS7IHHzd4F6 MXq0PEBp NYHvT3JKUUN3MDC9JFQvOjh5IN88US=> NGTKU5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkS0PFA{Pyd-Mk[0OFgxOzd:L3G+
cells after 48 hrs by SRB assay NGLOSJlEgXSxdH;4bYNqfHliYYPzZZk> MYPHTVUxKD1iMD6wNFE1QCEQvF2= Ml6yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ2NkKwOVIoRjJ4NE[yNFUzRC:jPh?=
HeLa NFTvblFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{HyVVczKGh? MnXqTWM2OCB;IEKuNlkh|ryP M4PFR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkCyPFI4Lz5{Nk[wNlgzPzxxYU6=
184B5 MYTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NYXnSog2PzJiaB?= NEHh[ohKSzVyIE2gNk4{OiEQvF2= MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZyMkiyO{c,OjZ4MEK4Nlc9N2F-
MDA-MB-231 NX\FTGRRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NVfOW|dqPzJiaB?= M13kW2lEPTBiPTCyMlU3KM7:TR?= NGjacFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[wNlgzPyd-Mk[2NFI5Ojd:L3G+
MDA-MB-468 NYPtfXZtSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NEfq[I44OiCq MoTSTWM2OCB;IEOuPFch|ryP M{X5R|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkCyPFI4Lz5{Nk[wNlgzPzxxYU6=
MCF7 MoHORY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYK3NkBp NYLnUYJsUUN3MDC9JFMvQTlizszN MnqyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4MEK4NlcoRjJ4NkCyPFI4RC:jPh?=
Jurkat NXT3OYhtS3m2b4TvfIlkcXS7IHHzd4F6 MYO0PEBp MnGxTWM2OCB;IECuNFAxPSEQvF2= M{HZWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkO4NFQyLz5{Nk[zPFA1OTxxYU6=
U937 MXfDfZRwfG:6aXPpeJkh[XO|YYm= Mn25OFghcA>? MkDyTWM2OCB;IECuNFA3KM7:TR?= MlO3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4M{iwOFEoRjJ4NkO4NFQyRC:jPh?=
HeLa MmPwR5l1d3SxeHnjbZR6KGG|c3H5 NEHjd|Q1QCCq NVPwfHYzUUN3MDC9JFAvODl7IN88US=> M{\jNFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkO4NFQyLz5{Nk[zPFA1OTxxYU6=
cells assessed as cell growth inhibition after 48 hrs by MTT assay NXuxOo9VS3m2b4TvfIlkcXS7IHHzd4F6 MXLJR|UxKD1iMD62OUDPxE1? Mlj6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4M{iwOFEoRjJ4NkO4NFQyRC:jPh?=
MDA-MB-231 NUPiWXVTS3m2b4TvfIlkcXS7IHHzd4F6 NHHjb3k4OiCq MVvJR|UxKD1iMD6wNFM6KM7:TR?= Ml;OQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4OUCyO|QoRjJ4NkmwNlc1RC:jPh?=
MCF7 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MX[3NkBp MWfJR|UxKD1iMD6wNFc1KM7:TR?= MkL1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4OUCyO|QoRjJ4NkmwNlc1RC:jPh?=
U937 Ml;YR5l1d3SxeHnjbZR6KGG|c3H5 MlviO|IhcA>? NX76O5FiUUN3MDC9JFAvODBzNk[g{txO NX:wWFdWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2PVc4OThpPkK2Olk4PzF6PD;hQi=>
HL60 NUDaSI1ZS3m2b4TvfIlkcXS7IHHzd4F6 NV\TfIFIPzJiaB?= MUTJR|UxKD1iMD6wNFE6QSEQvF2= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ7N{exPEc,OjZ4OUe3NVg9N2F-
A549 M2XzfWN6fG:2b4jpZ4l1gSCjc4PhfS=> MVq3NkBp MYHJR|UxKD1iMD6wNFIyOiEQvF2= NEG1RVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[5O|cyQCd-Mk[2PVc4OTh:L3G+
DU145 MoHpR5l1d3SxeHnjbZR6KGG|c3H5 MVy3NkBp NVzHUoloUUN3MDC9JFAvODB{MzFOwG0> NH7ESHU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[5O|cyQCd-Mk[2PVc4OTh:L3G+
HeLa MWnDfZRwfG:6aXPpeJkh[XO|YYm= MkPEO|IhcA>? NY\UZZh4UUN3MDC9JFAvODB|MEGg{txO MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ7N{exPEc,OjZ4OUe3NVg9N2F-
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HCT116 MlfBRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NVryXVZ2PDhiaB?= NH24c2ZKSzVyIE2gNE4xPjd{NzFOwG0> NFm2e3Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{CxO|I3PSd-MkewNVczPjV:L3G+
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NCI-H2073 MoHIRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYq0PEB1dyB7NjDo Mon2S2k2OCB;IEKuOEDPxE1? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzJzOEi2NEc,Ojd{MUi4OlA9N2F-
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HL-7702 NYDZR5ZFS3m2b4TvfIlkcXS7IHHzd4F6 M{PuU|czKGh? M2HnZ2lEPTBiPTCwMlA3KM7:TR?= M2q1NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5M{K5PVM5Lz5{N{OyPVk{QDxxYU6=
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HepG2 M4nMeWN6fG:2b4jpZ4l1gSCjc4PhfS=> NH;GclY4OiCq NFrvWmVKSzVyIE2gNE4zKM7:TR?= MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzN{OUmzPEc,Ojd|Mkm5N|g9N2F-
MCF7 NWKwXHE3S3m2b4TvfIlkcXS7IHHzd4F6 NIjaO2c6PiCq NGfZOYhKSzVyIE2gNE4xODB{IN88US=> NHznUGY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{SzOFQzPid-Mke0N|Q1OjZ:L3G+
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MCF7 NX\rU49bS3m2b4TvfIlkcXS7IHHzd4F6 NEnVU21KSzVyIE2gNE4xODB4IN88US=> NXPSeYVrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke0OFE5QTJpPkK3OFQyQDl{PD;hQi=>
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BGC823 M2C1PGN6fG:2b4jpZ4l1gSCjc4PhfS=> NFXHb2ZKSzVyIE2gNE4xODN|IN88US=> NX35XpM1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke0OFE5QTJpPkK3OFQyQDl{PD;hQi=>
HepG2 MXvDfZRwfG:6aXPpeJkh[XO|YYm= Ml3RTWM2OCB;IECuNFEzKM7:TR?= MkC5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd2NEG4PVIoRjJ5NESxPFkzRC:jPh?=
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A375 MnzWR5l1d3SxeHnjbZR6KGG|c3H5 NHXVO4dKSzVyIE2gNE4xOjJizszN NF;RWGs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{S0NVg6Oid-Mke0OFE5QTJ:L3G+
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HepG2 M3jRdWN6fG:2b4jpZ4l1gSCjc4PhfS=> M1PITVQ5KGh? M2\q[2lEPTBiPTCwMlAxPiEQvF2= M1P2R|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NkK3NVMxLz5{N{[yO|E{ODxxYU6=
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A549 M{nEfWN6fG:2b4jpZ4l1gSCjc4PhfS=> NILrXm01QCCq MlvrTWM2OCB;IECuNFMh|ryP NFTTN4Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{[yO|E{OCd-Mke2NlcyOzB:L3G+
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HeLa MmHHR5l1d3SxeHnjbZR6KGG|c3H5 MX63NkBp MV\JR|UxKD1iMT63JO69VQ>? M{LrZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{S4OVk2Lz5{N{e0PFU6PTxxYU6=
K562 M3\2eWN6fG:2b4jpZ4l1gSCjc4PhfS=> NH\Xd3k4OiCq M1frR2lEPTBiPTCyMlch|ryP NX3JeohwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3OFg2QTVpPkK3O|Q5PTl3PD;hQi=>
HCT116 NUHWNHFQS3m2b4TvfIlkcXS7IHHzd4F6 MUG3NkBp NF;uNHRKSzVyIE2gN{4{KM7:TR?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd2OEW5OUc,Ojd5NEi1PVU9N2F-
A549 MkLuR5l1d3SxeHnjbZR6KGG|c3H5 NXPHcFRlPzJiaB?= MWrJR|UxKD1iNT61JO69VQ>? MnvGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5NEi1PVUoRjJ5N{S4OVk2RC:jPh?=
HepG2 M4CzWGN6fG:2b4jpZ4l1gSCjc4PhfS=> MnrjO|IhcA>? M{fSV2lEPTBiPTC2Mlch|ryP MmrJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5NEi1PVUoRjJ5N{S4OVk2RC:jPh?=
HELF NHXvSFdEgXSxdH;4bYNqfHliYYPzZZk> M33FelI1KGh? NYXQe|ZTUUN3MDC9JFcvOTRizszN M1XvTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{[5NFMyLz5{N{e2PVA{OTxxYU6=
BGC823 M2\jd2N6fG:2b4jpZ4l1gSCjc4PhfS=> NFjK[GwzPCCq MmHiTWM2OCB;IEmuNlYh|ryP NUXUcW1PRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3OlkxOzFpPkK3O|Y6ODNzPD;hQi=>
KB MYnDfZRwfG:6aXPpeJkh[XO|YYm= NVriOYNNPDhiaB?= NYLmW|l5UUN3MDC9JFAvODByODFOwG0> NYrQVIQ{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3PVcyQTJpPkK3O|k4OTl{PD;hQi=>
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MDA-MB-231 MYTDfZRwfG:6aXPpeJkh[XO|YYm= NHvvfIU1QCCq NHjyWFVKSzVyIE2gNE4xODNyNTFOwG0> NIC0ZoE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{e5O|E6Oid-Mke3PVcyQTJ:L3G+
MCF7 M1TXcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NYLER4I6PDhiaB?= M1TpU2lEPTBiPTCwMlAzOjd3IN88US=> M{fUeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{m3NVkzLz5{N{e5O|E6OjxxYU6=
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HCT116 NE\ufnJEgXSxdH;4bYNqfHliYYPzZZk> M374R|Q5KGh? MornTWM2OCB;IECuNUDPxE1? M1nnUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OEi3PFQ{Lz5{N{i4O|g1OzxxYU6=
Bel7402 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NHrLXIg1QCCq MkWwTWM2OCB;IECuNUDPxE1? MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzh6N{i0N{c,Ojd6OEe4OFM9N2F-
OVCAR8 M1XLeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MnLYPVYhcA>? M3;aXGlEPTBiPTC1JO69VQ>? M1jsdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OEm0OVg6Lz5{N{i5OFU5QTxxYU6=
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