Paclitaxel (NSC 125973)

For research use only.

Catalog No.S1150 Synonyms: PTX, Taxol, Onxal, Abraxane

266 publications

Paclitaxel (NSC 125973) Chemical Structure

CAS No. 33069-62-4

Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.

Selleck's Paclitaxel (NSC 125973) has been cited by 266 publications

Purity & Quality Control

Choose Selective Antineoplastic and Immunosuppressive Antibiotics Inhibitors

Biological Activity

Description Paclitaxel (NSC 125973, PTX, Taxol, Onxal, Abraxane) is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
Targets
Microtubule (human endothelial cells) [1]
0.1 pM
In vitro

Paclitaxel inhibits non-endothelial type human cells at 104 - to 105 -fold higher concentrations, with IC50 of 1 nM-10 nM. The selectivity of Paclitaxel inhibition of cell proliferation is also species specific, as mouse ECs are not sensitive to Paclitaxel at ultra low concentrations. Inhibition of human ECs by Paclitaxel at ultra low concentrations does not affect the cellular microtubule structure, and the treated cells do not show G2/M cell cycle arrest and apoptosis, suggesting a novel but as yet unidentified mechanism of action. In an in vitro angiogenesis assay, Paclitaxel at ultra low concentrations blocks human ECs from forming sprouts and tubes in the three-dimensional fibrin matrix. [1] In the presence of SMF, the efficient concentration of Paclitaxel on K562 cells is decreased from 50 to 10 ng/mL. The cell cycle arrest effect of Paclitaxel with or without SMF on K562 cells is correlated with DNA damage. [2] Paclitaxel alone causes a time-dependent inhibition of CDK1 in four cell lines including A549 cells, H358, H1395 cells and H1666 cells. [3]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
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COLO-800 NFfBVmtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MnPGTWM2OCB;IEiuOFc5PyEQvF2= NXXOXVNPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
EB2 MmDkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NULDXW5qUUN3MDC9JFkvOTl6M{Wg{txO M{LvR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
ES3 MlXCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? MWfJR|UxKD1iOT6zNFY3PSEQvF2= MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
SKM-1 MkjvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHS1VmFKSzVyIE2gPU4{QTR3OTFOwG0> MmPxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
MFM-223 M1rCXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 NELqbGFKSzVyIE2gPU42ODF{NzFOwG0> MkLQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
LB2241-RCC NV36S3d{T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M{C0TWlEPTBiPTCxNE4xOzh4IN88US=> MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
EW-13 Mn\4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NEjLfmVKSzVyIE2gNVAvOzN|MzFOwG0> M2j0NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
D-283MED NEPXbnBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NEi0ZVlKSzVyIE2gNVAvPDl3OTFOwG0> MmjNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
EW-11 NF7YdHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M130b2lEPTBiPTCxNU43Pjl2IN88US=> M1vMc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
NCI-H128 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? Mk\oTWM2OCB;IEGyMlE{OzRizszN M4C3XlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
ES7 M1[zTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MVLJR|UxKD1iMUWuNlQ6PCEQvF2= MkGwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
AM-38 NHTESIVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M3\HWGlEPTBiPTCxOU41OTZ4IN88US=> MnvZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
NCI-H716 NInXfJhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MmnhTWM2OCB;IEG3MlkzQTlizszN NV:3ZYV3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
NCI-H1770 M4rPeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MV;JR|UxKD1iMUiuN|g2OSEQvF2= M4jQTVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
JVM-3 MkLHS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? Mn\vTWM2OCB;IEKwMlg6QDVizszN MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
CW-2 MXPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? NEe0dFdKSzVyIE2gNlEvOTN2OTFOwG0> NHLYflQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;3e5cv\WKrLnHjMpVsN2OqZX3icE9kd22yb4Xu[H9z\XCxcoTfZ4Fz\C:FSFXNRmw1Ojh4NEevK|5USU6JRWK8M4E,
YT NGftUm1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= NXrvXm8xUUN3MDC9JFIyNjR4OUGg{txO MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
C8166 NYHIN|hyT3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= M3jISmlEPTBiPTCyNk4zPzR4IN88US=> M4\zcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
SUP-T1 MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? MWPJR|UxKD1iMkOuNlUyOiEQvF2= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
KASUMI-1 MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>? M2OzVGlEPTBiPTCyN{42OTF7IN88US=> M{jjNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
IM-9 NITiUW5Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?= M{LneWlEPTBiPTCyN{43QTd7IN88US=> NU\YVmpNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
NH-12 MniyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NXfYcXVrUUN3MDC9JFI1NjF4NUSg{txO NUTLcIdqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
WSU-NHL MlzzS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NHvIOJFKSzVyIE2gNlUvPzJ4MTFOwG0> M1H6O|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
TUR NGnndFNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MYXJR|UxKD1iMk[uOlU{OyEQvF2= MoGxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xd4f3MoVjcS6jYz71b{9kcGWvYnyvZ49ueG:3bnTfdoVxd3K2X3PhdoQwS0iHTVLMOFI5PjR5Lze+V2FPT0WUPD;hQi=>
RL NUG0Wog4T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= NWT6N|VWUUN3MDC9JFI4NjJ{NEKg{txO MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
EW-12 MknvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl? NUjOOGRCUUN3MDC9JFI5NjB5MEKg{txO M{\oNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
KG-1 M3jxZmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7 MoH4TWM2OCB;IEK4MlI5PjVizszN M2rkR|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4f3e{5m[mlwYXOueYsw[2inbXLsM4NwdXCxdX7kY5JmeG:{dG;jZZJlN0OKRV3CUFQzQDZ2Nz:nQnNCVkeHUkyvZV4>
P31-FUJ NYTzTIp5T3Kxd4ToJGlvcGmkaYTpc44hSXO|YYm= MYDJR|UxKD1iMkmuNFQ5QSEQvF2= NXXlbJNNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:ve5d4NmWkaT7hZ{52cy:laHXtZoww[2:vcH;1coRgemWyb4L0Y4NiemRxQ1jFUWJNPDJ6NkS3M{c,W0GQR1XSQE9iRg>?
NB10 NETMVnFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?= MW\JR|UxKD1iM{GuOVA6KM7:TR?= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:5d4eu[YJqNmGlLoXrM4Np\W2kbD;jc41xd3WwZG;y[ZBwenShY3Hy[E9EUEWPQly0Nlg3PDdxJ{7TRW5ITVJ:L3G+
COLO205 MlP3R5l1d3SxeHnjbZR6KGG|c3H5 MWPHTVUxKD1iMD6wNFE4PiEQvF2= MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
SF539 NYXJSoV{S3m2b4TvfIlkcXS7IHHzd4F6 NGiwXoZIUTVyIE2gNE4xODN4NjFOwG0> MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek84QTB6OUWwK|44QTB6OUWwQE9iRg>?
SNB75 MVrDfZRwfG:6aXPpeJkh[XO|YYm= M3q1bmdKPTBiPTCwMlAxQDB6IN88US=> M2nzVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzd7MEi5OVAoRjd7MEi5OVA9N2F-
DMS114 M4DvfGN6fG:2b4jpZ4l1gSCjc4PhfS=> M4X2OGdKPTBiPTCwMlAyOjNizszN NWnHemdVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{mwPFk2OCd-N{mwPFk2ODxxYU6=
OVCAR-3 M{GxVGN6fG:2b4jpZ4l1gSCjc4PhfS=> MkPiS2k2OCB;IECuNFE6PyEQvF2= NUPGPIV3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxN{mwPFk2OCd-N{mwPFk2ODxxYU6=
NCI-H460 NITlPHZEgXSxdH;4bYNqfHliYYPzZZk> M1\3cWdKPTBiPTCwMlAzOTlizszN NILhZXU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi95OUC4PVUxLz55OUC4PVUxRC:jPh?=
HOP62 M2HSVWN6fG:2b4jpZ4l1gSCjc4PhfS=> M3zu[GdKPTBiPTCwMlA3PzFizszN Mkj5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwPzlyOEm1NEc,PzlyOEm1NFww[T5?
mammary carcinoma NFGz[XhEgXSxdH;4bYNqfHliYYPzZZk> M4m5dGlEPTBiPTCwMlI6QSEQvF2= M4XMeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzhzOEK2PVgoRjhzOEK2PVg9N2F-
NCI60 M371V2N6fG:2b4jpZ4l1gSCjc4PhfS=> NYHmXGNJT0l3MDC9JFAvODByNkWg{txO M{TpbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493Nzl2NkG2OVMoRjl2NkG2OVM9N2F-
MCF-7 MWXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mof6S2k2OCB;IECuNFAyOSEQvF2= NFPDXWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi97OEezOVk4Lz57OEezOVk4RC:jPh?=
murine leukemic P388 MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NXP6d2xWT0l3MDC9JFAvODF4IN88US=> NVfn[HFCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxOUi3N|U6Pyd-OUi3N|U6PzxxYU6=
KB NXHrNXJPS3m2b4TvfIlkcXS7IHHzd4F6 MX;JR|UxKD1iMD6wNFYh|ryP MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yODl5OEKwNEc,OTB7N{iyNFA9N2F-
MCF7 M3;oUWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NHO2TYI4OiCq MUTJR|UxKD1iMD6wNFIh|ryP NH:3bG49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMUOyOVIzPid-MUGzNlUzOjZ:L3G+
MCF-7 Mn[5R5l1d3SxeHnjbZR6KGG|c3H5 MUXFSFUxKD1iMD6wNFQh|ryP NVnZPZQ1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUGzN|Q2PjdpPkGxN|M1PTZ5PD;hQi=>
uterine sarcoma (MES-SA) MlzhR5l1d3SxeHnjbZR6KGG|c3H5 M2TkTGlEPTBiPTCwMlAxODB2IN88US=> MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yOTd{OEG5NUc,OTF5MkixPVE9N2F-
nonsmall cell lung carcinoma (NCI-H460) M2j6N2N6fG:2b4jpZ4l1gSCjc4PhfS=> NUjoWmVsUUN3MDC9JFAvODByMUSg{txO NYnGbVdnRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUG3NlgyQTFpPkGxO|I5OTlzPD;hQi=>
colon adenocarcinoma (HT-29) MlvPR5l1d3SxeHnjbZR6KGG|c3H5 M3voS2lEPTBiPTCwMlAxODF4IN88US=> M1K5RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzN{K4NVkyLz5zMUeyPFE6OTxxYU6=
prostate carcinoma (DU-145) MlfXR5l1d3SxeHnjbZR6KGG|c3H5 MkLGTWM2OCB;IECuNFA1QDlizszN M4PrS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzFzN{K4NVkyLz5zMUeyPFE6OTxxYU6=
SW626 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NF3yN4U4OiCq M3H3UGlEPTBiPTCwMlAxODBzIN88US=> M1;PclxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
Lu1 MUfDfZRwfG:6aXPpeJkh[XO|YYm= Mo\ZO|IhcA>? M2nuN2lEPTBiPTCwMlAyKM7:TR?= NF7WZ3Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkC4PFQzPSd-MUKwPFg1OjV:L3G+
MCF7 Moe0R5l1d3SxeHnjbZR6KGG|c3H5 NVXrb3kxPzJiaB?= MYHJR|UxKD1iMD6wNkDPxE1? M1fs[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF{MEi4OFI2Lz5zMkC4PFQzPTxxYU6=
P388 Mn3CR5l1d3SxeHnjbZR6KGG|c3H5 MXK3NkBp NHjlUo5KSzVyIE2gNE4xOiEQvF2= Mo[5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJyOEi0NlUoRjF{MEi4OFI2RC:jPh?=
LNCAP M2XPN2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoLjO|IhcA>? NI[xdFJKSzVyIE2gNE4xOiEQvF2= NUXHN|E5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
KB M4PZT2N6fG:2b4jpZ4l1gSCjc4PhfS=> Ml[yO|IhcA>? M4fhXmlEPTBiPTCwMlAzKM7:TR?= NXTaflR3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
Col2 MVPDfZRwfG:6aXPpeJkh[XO|YYm= M2HjRlczKGh? Moi5TWM2OCB;IECuNFIh|ryP NFHvRVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkC4PFQzPSd-MUKwPFg1OjV:L3G+
BC1 MWDDfZRwfG:6aXPpeJkh[XO|YYm= NWfJW4UzPzJiaB?= NFXJcFVKSzVyIE2gNE4xOiEQvF2= NYnZfIJTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUKwPFg1OjVpPkGyNFg5PDJ3PD;hQi=>
SK-MEL-2 MkfLR5l1d3SxeHnjbZR6KGG|c3H5 MnXGO|IhcA>? NIPTW3dKSzVyIE2gNE4xPyEQvF2= NFrGTmE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMkC4PFQzPSd-MUKwPFg1OjV:L3G+
L2987 MUfDfZRwfG:6aXPpeJkh[XO|YYm= M1LNO2lEPTBiPTCwMlIh|ryP Mm\zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTJ2NEO3PFMoRjF{NESzO|g{RC:jPh?=
colon adenocarcinoma RKO MlzMR5l1d3SxeHnjbZR6KGG|c3H5 MXnJR|UxKD1iMD6wNUDPxE1? NIrlTpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zMki1Nlc3QCd-MUK4OVI4Pjh:L3G+
NCI-H460 NV3QVldvS3m2b4TvfIlkcXS7IHHzd4F6 MYC0PEBp NXzhUXA5UUN3MDC9JFAvODB7NTFOwG0> NEnP[|k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNE[5OVc6QCd-MUS2PVU4QTh:L3G+
MCF7 NW[0bI1CS3m2b4TvfIlkcXS7IHHzd4F6 NETNOoQ1QCCq NVrDN4xOUUN3MDC9JFAvODFzMjFOwG0> NF3TTXM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNE[5OVc6QCd-MUS2PVU4QTh:L3G+
SF268 NWXtOY9bS3m2b4TvfIlkcXS7IHHzd4F6 NFPsTlA1QCCq M1q2PWlEPTBiPTCwMlAzOTdizszN MnyyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR4OUW3PVgoRjF2Nkm1O|k5RC:jPh?=
MDA-MB-231 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NVK2OZpCPDhiaB?= NHraeI9KSzVyIE2gNE4xODR3IN88US=> NHvGfpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2OSd-MUS5PFcxPTF:L3G+
MCF7 MnzyR5l1d3SxeHnjbZR6KGG|c3H5 NWXpWXdVPDhiaB?= NYPqXmViUUN3MDC9JFAvODB2OTFOwG0> MlK4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTR7OEewOVEoRjF2OUi3NFUyRC:jPh?=
A2780 MVTDfZRwfG:6aXPpeJkh[XO|YYm= NGntZ241QCCq MVjJR|UxKD1iMD6wNlUh|ryP M1i3d|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF2OUi3NFUyLz5zNEm4O|A2OTxxYU6=
PC3 M1Ts[mN6fG:2b4jpZ4l1gSCjc4PhfS=> MVq0PEBp MYXJR|UxKD1iMD6wO|ch|ryP NEPMXIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNEm4O|A2OSd-MUS5PFcxPTF:L3G+
MCF7 NF7MSZFEgXSxdH;4bYNqfHliYYPzZZk> NYXLR403PzJiaB?= NXrXfJl5UUN3MDC9JFAvODBzNDFOwG0> MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPDl6N{C1Okc,OTR7OEewOVY9N2F-
multidrug-resistant MCF7 Mm\DR5l1d3SxeHnjbZR6KGG|c3H5 NWfDUm1HPzJiaB?= MXTJR|UxKD1iMD6zOVQh|ryP NYn1WWpsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUS5PFcxPTZpPkG0PVg4ODV4PD;hQi=>
PC3 MkTNR5l1d3SxeHnjbZR6KGG|c3H5 NFTQN2g1QCCq NVXlVJFJUUN3MDC9JFAvODF4IN88US=> Ml30QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFIoRjF3MESzOFAzRC:jPh?=
Hep3B MmXBR5l1d3SxeHnjbZR6KGG|c3H5 M2\lO|Q5KGh? NWqwcGpMUUN3MDC9JFAvODNzIN88US=> NFXI[pY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxOid-MUWwOFM1ODJ:L3G+
NCI-H460 NFzWVpdEgXSxdH;4bYNqfHliYYPzZZk> NVe3coRMPDhiaB?= NFi3c5FKSzVyIE2gNE4xODl3IN88US=> MkWxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFQoRjF3MESzOFA1RC:jPh?=
MCF7 MWDDfZRwfG:6aXPpeJkh[XO|YYm= MVm0PEBp NGfqVXZKSzVyIE2gNE4xOTF{IN88US=> NGDXW2E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPCd-MUWwOFM1ODR:L3G+
SF268 MlL0R5l1d3SxeHnjbZR6KGG|c3H5 MkTuOFghcA>? NXTkWHBYUUN3MDC9JFAvODJzNzFOwG0> Mo\kQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTVyNEO0NFQoRjF3MESzOFA1RC:jPh?=
KB M4TWc2N6fG:2b4jpZ4l1gSCjc4PhfS=> Ml;WSWQ2OCB;IECuNFAxPCEQvF2= NWfrPJM6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
Lu1 NEXxb3ZEgXSxdH;4bYNqfHliYYPzZZk> NFvxVIJGTDVyIE2gNE4xODJizszN NWO2b2NRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
LNCAP Mn3pR5l1d3SxeHnjbZR6KGG|c3H5 M1TMW2VFPTBiPTCwMlAxPSEQvF2= NUfGOWlMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
RPE1 MlTTR5l1d3SxeHnjbZR6KGG|c3H5 M3\ZdmVFPTBiPTCwMlAzOyEQvF2= NEjKZow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUC0N|QxPyd-MUWwOFM1ODd:L3G+
Col2 NWnpZ45sS3m2b4TvfIlkcXS7IHHzd4F6 MXzFSFUxKD1iMD6wOFYh|ryP NVjtemRbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUWwOFM1ODdpPkG1NFQ{PDB5PD;hQi=>
T47D MWTBdI9xfG:|aYOgZZN{[Xl? MWiyOEBp NVP3[FZkTUN3MDC9JFAvODNizszN MnzFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV3Nk[zNFAoRjF3NU[2N|AxRC:jPh?=
DLD1 MoLyRZBweHSxc3nzJIF{e2G7 NY\jXpdZOjRiaB?= MV;FR|UxKD1iMD6wO|Uh|ryP MnnuQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTV3Nk[zNFAoRjF3NU[2N|AxRC:jPh?=
H1299 NFz6[lZCeG:ydH;zbZMh[XO|YYm= NGfXN3EzPCCq NYfEe|EzTUN3MDC9JFAvOTZ|IN88US=> NHXmWWE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUW2OlMxOCd-MUW1OlY{ODB:L3G+
VA13 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NUCze|I1PDhiaB?= NG\WOnZKSzVyIE2gNE4xODVizszN MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPTd|MEK0N{c,OTV5M{CyOFM9N2F-
WI 38 MnfYR5l1d3SxeHnjbZR6KGG|c3H5 MY[0PEBp MUXJR|UxKD1iMD6wOEDPxE1? M2jVXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{OwNlQ{Lz5zNUezNFI1OzxxYU6=
Hep G2 MoC1R5l1d3SxeHnjbZR6KGG|c3H5 NV72cW9mPDhiaB?= NVnGTZVkUUN3MDC9JFgvOSEQvF2= M4HNUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF3N{OwNlQ{Lz5zNUezNFI1OzxxYU6=
A549 NHXpbYlEgXSxdH;4bYNqfHliYYPzZZk> Mli3OFghcA>? MnXkTWM2OCB;IEGuNlUh|ryP NHnQdpc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe4O|Q3OCd-MUW3PFc1PjB:L3G+
SKOV3 NGjleIxEgXSxdH;4bYNqfHliYYPzZZk> NEfGW2g1QCCq NWXQelhyUUN3MDC9JFEvOzVizszN NHLVWnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNUe4O|Q3OCd-MUW3PFc1PjB:L3G+
KB M{LIV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NVn5e5ozOyCmYYnz MUDJR|UxKD1iMD6wNFEh|ryP M37rOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4MEO4OVQ2Lz5zNkCzPFU1PTxxYU6=
1A9 M{XFe2N6fG:2b4jpZ4l1gSCjc4PhfS=> NYX5NZRJOyCmYYnz NGK1fm9KSzVyIE2gNE4xODJizszN MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjB|OEW0OUc,OTZyM{i1OFU9N2F-
HCT8 NUPEemI1S3m2b4TvfIlkcXS7IHHzd4F6 M3v2cVMh\GG7cx?= MnKyTWM2OCB;IECuNFE{KM7:TR?= NEnURpo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkCzPFU1PSd-MU[wN|g2PDV:L3G+
A431 NIrINFdE\WyuIHP5Z4xmKGG{cnXzeEBie3OjeR?= M1qwcWVEPTBiPTCwMlAxQSEQvF2= M2PWT|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4M{e3NVg4Lz5zNkO3O|E5PzxxYU6=
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WI38 MmPvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NFXQd4Y1QCCq M{\ReWlEPTBiPTCwMlA{PCEQvF2= M1\EZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NEm5N|IzLz5zNkS5PVMzOjxxYU6=
HepG2 NVL6eFl2T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV\ieokyPDhiaB?= M4rQR2lEPTBiPTC2Mlkh|ryP MoiyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ2OUmzNlIoRjF4NEm5N|IzRC:jPh?=
Aro M1vYbWN6fG:2b4jpZ4l1gSCjc4PhfS=> MlO5TWM2OCB;IECuNFAxOiEQvF2= NFvncVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
PT45 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MmLHTWM2OCB;IECuNFA2KM7:TR?= NXvZW41CRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
A549 M2Dje2N6fG:2b4jpZ4l1gSCjc4PhfS=> MUfJR|UxKD1iMD6wNFYh|ryP MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV|OUO3O{c,OTZ3M{mzO|c9N2F-
MCF7 NX;mR|FtS3m2b4TvfIlkcXS7IHHzd4F6 MmrUTWM2OCB;IECuNFA4KM7:TR?= NV\WNIZYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
HeLa MW\DfZRwfG:6aXPpeJkh[XO|YYm= MoSzTWM2OCB;IECuNFA5KM7:TR?= NVvQUWk3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
Ovcar3 MUDDfZRwfG:6aXPpeJkh[XO|YYm= NW\6eJhWUUN3MDC9JFAvODFizszN NE\0WIk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNkWzPVM4Pyd-MU[1N|k{Pzd:L3G+
HT29 MYTDfZRwfG:6aXPpeJkh[XO|YYm= NWLxSIszUUN3MDC9JFAvODVizszN MnvJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
H295R NELCcY1EgXSxdH;4bYNqfHliYYPzZZk> NVrNV|hlUUN3MDC9JFAvODhizszN M{jNUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NUO5N|c4Lz5zNkWzPVM4PzxxYU6=
BNL MXXDfZRwfG:6aXPpeJkh[XO|YYm= NI\3O4ZKSzVyIE2gNE4zKM7:TR?= Mn35QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3M{mzO|coRjF4NUO5N|c4RC:jPh?=
4T1 MYrDfZRwfG:6aXPpeJkh[XO|YYm= MX7JR|UxKD1iMD6yJO69VQ>? NUDzSFZGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
HepG2 MVPDfZRwfG:6aXPpeJkh[XO|YYm= NHXESJRKSzVyIE2gNE4{KM7:TR?= NX\kXYRKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[1N|k{PzdpPkG2OVM6Ozd5PD;hQi=>
U937 GTB NHLDNndEgXSxdH;4bYNqfHliYYPzZZk> MmDVO|IhcA>? M3rWSmlEPTBiPTCwMlAxPTlizszN MorXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ3NkK4OFAoRjF4NU[yPFQxRC:jPh?=
RPMI 8226/s MUHDfZRwfG:6aXPpeJkh[XO|YYm= Mon2O|IhcA>? MWDJR|UxKD1iMD6wNFch|ryP MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjV4Mki0NEc,OTZ3NkK4OFA9N2F-
CEM/s MYrDfZRwfG:6aXPpeJkh[XO|YYm= Mln1O|IhcA>? NYHUN5RDUUN3MDC9JFAvODB5IN88US=> M2CzcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4NU[yPFQxLz5zNkW2Nlg1ODxxYU6=
VA13 MXHDfZRwfG:6aXPpeJkh[XO|YYm= MUHJR|UxKD1iMD6wNFU6KM7:TR?= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjd{NEi0Nkc,OTZ5MkS4OFI9N2F-
WI38 NXLWO45xS3m2b4TvfIlkcXS7IHHzd4F6 MoDtTWM2OCB;IECuNFQ3QCEQvF2= M3T0UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF4N{K0PFQzLz5zNkeyOFg1OjxxYU6=
HepG2 NEjC[VhEgXSxdH;4bYNqfHliYYPzZZk> NW\jb|k2UUN3MDC9JFkvPDlizszN NYK4XYdCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[3NlQ5PDJpPkG2O|I1QDR{PD;hQi=>
HT29 MYnDfZRwfG:6aXPpeJkh[XO|YYm= NIC0eYxGSzVyIE2gNE4xODZizszN NGfIOoQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNki3NFQzQCd-MU[4O|A1Ojh:L3G+
K562 NHv5c21EgXSxdH;4bYNqfHliYYPzZZk> M2PJcGVEPTBiPTCwMlAyPCEQvF2= MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPjh5MESyPEc,OTZ6N{C0Nlg9N2F-
MCF7 M1T5c2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mk\HSWM2OCB;IECuNFM3KM7:TR?= NGHXXnY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zNki3NFQzQCd-MU[4O|A1Ojh:L3G+
VA-13 M332[mN6fG:2b4jpZ4l1gSCjc4PhfS=> MnnUTWM2OCB;IECuNFA2KM7:TR?= NYjBNFVuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMU[5N|M5PjhpPkG2PVM{QDZ6PD;hQi=>
WI38 M3;acGN6fG:2b4jpZ4l1gSCjc4PhfS=> NEHoXFZKSzVyIE2gNE4xPCEQvF2= Mli1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTZ7M{O4OlgoRjF4OUOzPFY5RC:jPh?=
VA13 NVLKRVRlS3m2b4TvfIlkcXS7IHHzd4F6 MWjJR|UxKD1iMD6wNFUh|ryP NYn2[oJNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUewOlcyPTVpPkG3NFY4OTV3PD;hQi=>
WI38 NEfEcohEgXSxdH;4bYNqfHliYYPzZZk> MVrJR|UxKD1iMD6wOEDPxE1? MoPUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdyNkexOVUoRjF5ME[3NVU2RC:jPh?=
Hep G2 M4nTNmN6fG:2b4jpZ4l1gSCjc4PhfS=> NXP1dY4{UUN3MDC9JFgvOSEQvF2= NFfmTI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{C2O|E2PSd-MUewOlcyPTV:L3G+
TW01 M3n4c2N6fG:2b4jpZ4l1gSCjc4PhfS=> M3;W[GlEPTBiPTCwMlAxODNizszN M3X1fVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
MCF7 NVLDWmN5S3m2b4TvfIlkcXS7IHHzd4F6 NYXuNWhjUUN3MDC9JFAvODByNTFOwG0> M3jzd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
MKN45 NX;ib|ZqS3m2b4TvfIlkcXS7IHHzd4F6 NVWzOnFHUUN3MDC9JFAvODByNTFOwG0> NEC1c4k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{GxN|I5QCd-MUexNVMzQDh:L3G+
MES-SA NHTye4pEgXSxdH;4bYNqfHliYYPzZZk> NEjzPYJKSzVyIE2gNE4xODB3IN88US=> MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
HCT116 MXfDfZRwfG:6aXPpeJkh[XO|YYm= NHzjdI5KSzVyIE2gNE4xODB4IN88US=> M{nNcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
RPTEC Mme4R5l1d3SxeHnjbZR6KGG|c3H5 MWnJR|UxKD1iMD6wNFA6KM7:TR?= MmDNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
Hep3B M2HGSmN6fG:2b4jpZ4l1gSCjc4PhfS=> M3fZXGlEPTBiPTCwMlAxPTRizszN MmHlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzMUOyPFgoRjF5MUGzNlg5RC:jPh?=
NCI-H226 NFrHdYJEgXSxdH;4bYNqfHliYYPzZZk> NH3RfldKSzVyIE2gNE4xODZ6IN88US=> MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzFzM{K4PEc,OTdzMUOyPFg9N2F-
A498 MonmR5l1d3SxeHnjbZR6KGG|c3H5 MV7JR|UxKD1iMD6wOlEh|ryP M1nPdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUGzNlg5Lz5zN{GxN|I5QDxxYU6=
MDA435/LCC6 NVfRXGh7SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MUXJR|UxKD1iMD6wNFI6KM7:TR?= NFjPSG49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1OFUxPSd-MUexOVQ2ODV:L3G+
multidrug resistant MDA435/LCC6 MmrQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MmTjTWM2OCB;IECuNFA1QCEQvF2= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF3NEWwOUc,OTdzNUS1NFU9N2F-
P388 NFzydoJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MmruTWM2OCB;IECuNFIzKM7:TR?= NFTTTGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1OFUxPSd-MUexOVQ2ODV:L3G+
adriamycin resistant P388 NGO1c3hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MnHmTWM2OCB;IECuNFMh|ryP NFnZZ5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G1OFUxPSd-MUexOVQ2ODV:L3G+
LT12 NVKxRXI1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M2DTXFQ5KGh? M37LeGlEPTBiPTCwMlAxPiEQvF2= M17oN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MUixNVY1Lz5zN{G4NVE3PDxxYU6=
SKOV3 MlTQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYi0PEBp M4r5bmlEPTBiPTCwMlAyKM7:TR?= Mm\YQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
NCI-H460 NFjYUG5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NXvMXoV1PDhiaB?= MoPpTWM2OCB;IECuNFEh|ryP NEe2WW09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
SF268 M4O1XmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MYi0PEBp MlfQTWM2OCB;IECuNFEh|ryP MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
RKO M{f3b2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NV3Z[nFLPDhiaB?= NYfvTop5UUN3MDC9JFAvODFizszN NHX0bnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{G4NVE3PCd-MUexPFEyPjR:L3G+
KB/HeLa NXTqPGwySW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M1rjV|Q5KGh? MV7JR|UxKD1iMD6wNUDPxE1? MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzF6MUG2OEc,OTdzOEGxOlQ9N2F-
P388 Ml\ERY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NV7KfZg6PDhiaB?= MXzJR|UxKD1iMD6wOEDPxE1? Ml3TQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
L1210 M3q4ZmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWW0PEBp NWjWTVdJUUN3MDC9JFAvODZizszN NV\YV|RLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUexPFEyPjRpPkG3NVgyOTZ2PD;hQi=>
LT12 MDR MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M1;wNFQ5KGh? MXjJR|UxKD1iMD60JO69VQ>? MnnCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTdzOEGxOlQoRjF5MUixNVY1RC:jPh?=
A2780 NIfMdVlEgXSxdH;4bYNqfHliYYPzZZk> M3fq[WlEPTBiPTCwMlAxOSEQvF2= M3jaUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
A2780-1A9 MlnhR5l1d3SxeHnjbZR6KGG|c3H5 NHi5S|JKSzVyIE2gNE4xODFzIN88US=> NInj[pg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KwOlE{QSd-MUeyNFYyOzl:L3G+
A549 M4DHPGN6fG:2b4jpZ4l1gSCjc4PhfS=> MX\JR|UxKD1iMD6wNFM3KM7:TR?= MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJyNkGzPUc,OTd{ME[xN|k9N2F-
1A9PTX22 MkTRR5l1d3SxeHnjbZR6KGG|c3H5 NF3UTZpKSzVyIE2gNE4xOTlizszN M2XXTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkC2NVM6Lz5zN{KwOlE{QTxxYU6=
1A9PTX10 NF;xUIxEgXSxdH;4bYNqfHliYYPzZZk> M3TBVWlEPTBiPTCwMlA{KM7:TR?= MknwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{ME[xN|koRjF5MkC2NVM6RC:jPh?=
A2780AD M3LmemN6fG:2b4jpZ4l1gSCjc4PhfS=> NYnDPGFiUUN3MDC9JFAvQSEQvF2= NYTMWFRrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNFYyOzlpPkG3NlA3OTN7PD;hQi=>
KB NWnEO4lvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYDJR|UxKD1iMD6wNFI1PSEQvF2= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzJ{OEi3N{c,OTd{Mki4O|M9N2F-
COLO205 NXvTTFRxS3m2b4TvfIlkcXS7IHHzd4F6 M4HsbWlEPTBiPTCwMlAxOzNizszN NV\UcmxHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNlg5PzNpPkG3NlI5QDd|PD;hQi=>
KB8.5 MY\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M2fmR2lEPTBiPTCwMlAzPiEQvF2= NWLTN5dpRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUeyNlg5PzNpPkG3NlI5QDd|PD;hQi=>
KBV1 NHzOfFlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3W2U2lEPTBiPTCyMlAyOyEQvF2= NFH3XY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{KyPFg4Oyd-MUeyNlg5PzN:L3G+
A2780 MonpR5l1d3SxeHnjbZR6KGG|c3H5 NHrPS3pKSzVyIE2gNE4xODB5IN88US=> M3LOSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5MkO5OVk4Lz5zN{KzPVU6PzxxYU6=
2780AD MlfIR5l1d3SxeHnjbZR6KGG|c3H5 MWLJR|UxKD1iMD61N|Uh|ryP MkX0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd{M{m1PVcoRjF5MkO5OVk4RC:jPh?=
1A9 NVX4bWhrS3m2b4TvfIlkcXS7IHHzd4F6 MnXBSWQ2OCB;IECuNFAyKM7:TR?= M1npSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
MCF7 MXfDfZRwfG:6aXPpeJkh[XO|YYm= MXXFSFUxKD1iMD6wNFEyKM7:TR?= NFLYc3Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O1NFg{PCd-MUezOVA5OzR:L3G+
DU145 MVLDfZRwfG:6aXPpeJkh[XO|YYm= Mn;GSWQ2OCB;IECuNFAyOyEQvF2= MljiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|NUC4N|QoRjF5M{WwPFM1RC:jPh?=
KB NWi1dnUyS3m2b4TvfIlkcXS7IHHzd4F6 M3S1TmVFPTBiPTCwMlAxOThizszN MkfKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd|NUC4N|QoRjF5M{WwPFM1RC:jPh?=
A549 NFjYd|VEgXSxdH;4bYNqfHliYYPzZZk> M4f4Z2VFPTBiPTCwMlAxOjNizszN M2HL[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
LNCAP NHTXU4pEgXSxdH;4bYNqfHliYYPzZZk> MknqSWQ2OCB;IECuNFAzPiEQvF2= NGDXco89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{O1NFg{PCd-MUezOVA5OzR:L3G+
PC3 NX;3cWpvS3m2b4TvfIlkcXS7IHHzd4F6 MYrFSFUxKD1iMD6wOVU2KM7:TR?= M1;jNVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5M{WwPFM1Lz5zN{O1NFg{PDxxYU6=
KBVIN MVrDfZRwfG:6aXPpeJkh[XO|YYm= NHfDeG1GTDVyIE2gNE4{OTFizszN MV:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN3MEizOEc,OTd|NUC4N|Q9N2F-
A2780 NHTNUGhEgXSxdH;4bYNqfHliYYPzZZk> NWj6eoRzUUN3MDC9JFAvODBzNjFOwG0> MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN7NUS2OUc,OTd|OUW0OlU9N2F-
A2780/AD NWPOZ|UxS3m2b4TvfIlkcXS7IHHzd4F6 M2nETWlEPTBiPTCwMlkzKM7:TR?= MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzN7NUS2OUc,OTd|OUW0OlU9N2F-
KB M3zjVGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NH\ESGJKSzVyIE2gNE4xODJ2NTFOwG0> M3rqXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG2OVI1Lz5zN{SxOlUzPDxxYU6=
COLO205 MmftR5l1d3SxeHnjbZR6KGG|c3H5 MnjRTWM2OCB;IECuNFA{OyEQvF2= NIHyZ3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{SxOlUzPCd-MUe0NVY2OjR:L3G+
KB8.5 NIXSWoVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NV3ZVnQ2UUN3MDC9JFAvODJ4IN88US=> M4fFWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG2OVI1Lz5zN{SxOlUzPDxxYU6=
KBV1 MVjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NXXDcWxqUUN3MDC9JFIvODF|IN88US=> NYqwNpBbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVY2OjRpPkG3OFE3PTJ2PD;hQi=>
neural precursor M2C4dWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MVnFR|UxKD1iMD6wNUDPxE1? MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzN{[zNUc,OTd2MUe2N|E9N2F-
OVCAR-3 MYPDfZRwfG:6aXPpeJkh[XO|YYm= NHTEVXVKSzVyIE2gNE4xODB{IN88US=> MoDkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUmwOlUoRjF5NEG5NFY2RC:jPh?=
MDA-MB-231 MYHDfZRwfG:6aXPpeJkh[XO|YYm= M{PDcmlEPTBiPTCwMlAxPDVizszN MljLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2MUmwOlUoRjF5NEG5NFY2RC:jPh?=
MCF7 MVLDfZRwfG:6aXPpeJkh[XO|YYm= M2HrUGlEPTBiPTCwMlAxPDlizszN NVTiT41HRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
NCI-H1299 MnTLR5l1d3SxeHnjbZR6KGG|c3H5 M{XBSlk3KGh? M1LvXmlEPTBiPTCwMlAyPSEQvF2= NUja[JZ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0NVkxPjVpPkG3OFE6ODZ3PD;hQi=>
A2780 NH\ER|NEgXSxdH;4bYNqfHliYYPzZZk> M3KxVmlEPTBiPTCwMlAzPSEQvF2= M3rOfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
PC3 MXHDfZRwfG:6aXPpeJkh[XO|YYm= NUW2ZYN4UUN3MDC9JFAvODd5IN88US=> M{fqflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEG5NFY2Lz5zN{SxPVA3PTxxYU6=
LoVo M3rYW2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmPlTWM2OCB;IECuNFkh|ryP MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
L2987 M13xUmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mln3TWM2OCB;IECuNkDPxE1? MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzRzOUC2OUc,OTd2MUmwOlU9N2F-
cells MoHYR5l1d3SxeHnjbZR6KGG|c3H5 NXXpWnNZUUN3MDC9JFAvODB3OTFOwG0> NVzYbmx{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0OFI2PzdpPkG3OFQzPTd5PD;hQi=>
cells NFPGXXlEgXSxdH;4bYNqfHliYYPzZZk> NEfsTolKSzVyIE2gNE4xOSEQvF2= M3z2NlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEi1NlA4Lz5zN{S4OVIxPzxxYU6=
A2780 MnnDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGX1PYtKSzVyIE2gNE4xODJ6IN88US=> NYDhS5Z3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVA5PzhpPkG3OFkxQDd6PD;hQi=>
VA13 MUTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkXvTWM2OCB;IECuNFA2KM7:TR?= NGGwT4U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{S5NFg4QCd-MUe0PVA5Pzh:L3G+
WI38 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NF;mOZFKSzVyIE2gNE4xPCEQvF2= Ml7TQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUC4O|goRjF5NEmwPFc5RC:jPh?=
2780AD M1vxSmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1HoRmlEPTBiPTCwMlE5OyEQvF2= M2XLeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEmwPFc5Lz5zN{S5NFg4QDxxYU6=
HepG2 MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MlfmTWM2OCB;IEiuNUDPxE1? M1f5V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NEmwPFc5Lz5zN{S5NFg4QDxxYU6=
HT29 MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MnuzOFghcA>? MnjjS2k2OCB;IECuNFE2KM7:TR?= MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzR7OEm2NEc,OTd2OUi5OlA9N2F-
M21 M{\5Z2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M2j4flQ5KGh? MlnoS2k2OCB;IECuNFM4KM7:TR?= MoLjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd2OUi5OlAoRjF5NEm4PVYxRC:jPh?=
MCF7 NHu2OYVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUS0PEBp NFnGZZdIUTVyIE2gNE4xPTRizszN NVr4U5VFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe0PVg6PjBpPkG3OFk5QTZyPD;hQi=>
1A9 M2qyT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHfl[Yw4OiCq NFPvVWVIUTVyIE2gNE4xODB5MTFOwG0> NV3tWpU{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OFI2PzJpPkG3OVQzPTd{PD;hQi=>
1A9/Ptx22 MlHVS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXO3NkBp NXLmTGNXT0l3MDC9JFAvODVzIN88US=> MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzV2MkW3Nkc,OTd3NEK1O|I9N2F-
1A9/Ptx10 M{D0[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmLRO|IhcA>? M3q0[mdKPTBiPTCwMlA3PCEQvF2= M2nzVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5NUSyOVczLz5zN{W0NlU4OjxxYU6=
cells expressing MRP1 NUHBXlluT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= Moj2TWM2OCB;IECuNFAzPSEQvF2= NWPlfoJkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe1OlcyOjFpPkG3OVY4OTJzPD;hQi=>
cells expressing Pgp/MRP1 M1Sz[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3LJZmlEPTBiPTCyMlch|ryP MkLsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd3NkexNlEoRjF5NU[3NVIyRC:jPh?=
VA13 MnHRS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1fWU2lEPTBiPTC1JO69VQ>? NFe2fZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{W5OVE{PCd-MUe1PVUyOzR:L3G+
MCF7 MXLGeY5kfGmxbjDhd5NigQ>? NGPZUm5KSzVyIE2gNE4xODF6IN88US=> MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZyMUezPUc,OTd4MEG3N|k9N2F-
adriamycin-resistant MCF7 NV;nXYFNTnWwY4Tpc44h[XO|YYm= MnfJTWM2OCB;IEiuNkDPxE1? MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZyMUezPUc,OTd4MEG3N|k9N2F-
RPMI8226 Mk\OR5l1d3SxeHnjbZR6KGG|c3H5 NH3NNFFIUTVyIE2gNE4xODJizszN MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
HT29 NFnLNXJEgXSxdH;4bYNqfHliYYPzZZk> M3rscWdKPTBiPTCwMlAxOiEQvF2= MoLkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
COLO205 MkLtR5l1d3SxeHnjbZR6KGG|c3H5 MVXHTVUxKD1iMD6wNFMh|ryP NX\wNJJ5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
HCC2998 NVHlS5FmS3m2b4TvfIlkcXS7IHHzd4F6 MljZS2k2OCB;IECuNFA{KM7:TR?= MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
HS578T MmnyR5l1d3SxeHnjbZR6KGG|c3H5 M1vQNWdKPTBiPTCwMlAxOyEQvF2= NUC1cppJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe2PVY{OzJpPkG3Olk3OzN{PD;hQi=>
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SK-OV3 MmfSR5l1d3SxeHnjbZR6KGG|c3H5 NXnPeoxbT0l3MDC9JFAvODB6IN88US=> MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzZ7NkOzNkc,OTd4OU[zN|I9N2F-
NCI-H322M NFTse4ZEgXSxdH;4bYNqfHliYYPzZZk> MnfLS2k2OCB;IECuNFE{KM7:TR?= NFXCXJA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{[5OlM{Oid-MUe2PVY{OzJ:L3G+
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ACHN M3vBV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NFG5bZFIUTVyIE2gNE4{QThizszN Mn7JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd4OU[zN|IoRjF5Nkm2N|MzRC:jPh?=
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BEL-7402 MlX6R5l1d3SxeHnjbZR6KGG|c3H5 M2GxcFI1KGh? NGPucJFKSzVyIE2gNE46OyEQvF2= NVLHeI1zRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe4PVY5OTZpPkG3PFk3QDF4PD;hQi=>
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HepG2 M4qzfWN6fG:2b4jpZ4l1gSCjc4PhfS=> NFm3PYpKSzVyIE2gNE45OiEQvF2= MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzMUCxO{c,OTd7MUGwNVc9N2F-
BGC823 M17jfGN6fG:2b4jpZ4l1gSCjc4PhfS=> NH60OnVKSzVyIE2gNU4yPSEQvF2= NG\EN4s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxNVAyPyd-MUe5NVExOTd:L3G+
Aro NH7oTGVEgXSxdH;4bYNqfHliYYPzZZk> MYW3NkBp M1WzZWlEPTBiPTCwMlAxODJizszN MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
PT45 NGj5N2lEgXSxdH;4bYNqfHliYYPzZZk> NV:1UVAyPzJiaB?= NVLrfng3UUN3MDC9JFAvODB3IN88US=> MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
A549 NWHJb5I6S3m2b4TvfIlkcXS7IHHzd4F6 NYfoSnI4PzJiaB?= NYX6TGZJUUN3MDC9JFAvODB4IN88US=> NFfPcI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
MCF7 NFf0N5REgXSxdH;4bYNqfHliYYPzZZk> Mnr1O|IhcA>? M{nzZmlEPTBiPTCwMlAxPyEQvF2= NGiwbpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
HeLa MmPlR5l1d3SxeHnjbZR6KGG|c3H5 NHzCOWo4OiCq M2XPfGlEPTBiPTCwMlAxQCEQvF2= MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
Ovcar3 NYTiVGx6S3m2b4TvfIlkcXS7IHHzd4F6 NV;LenFZPzJiaB?= MX3JR|UxKD1iMD6wNUDPxE1? M{f3ZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUG1PFUyLz5zN{mxOVg2OTxxYU6=
HT29 M3;UXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MWi3NkBp M3ju[GlEPTBiPTCwMlA2KM7:TR?= NWXKRmVyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
A549T12 M1nQcWN6fG:2b4jpZ4l1gSCjc4PhfS=> MYC3NkBp NXrETWM1UUN3MDC9JFAvODZizszN MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
H295R MUnDfZRwfG:6aXPpeJkh[XO|YYm= NIj2Wpg4OiCq NXjLVoI3UUN3MDC9JFAvODhizszN MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
A549T24 NVvJToJ5S3m2b4TvfIlkcXS7IHHzd4F6 NYTyUHJ{PzJiaB?= NHG5UZJKSzVyIE2gNE4yODJizszN NYHacGprRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5NVU5PTFpPkG3PVE2QDVzPD;hQi=>
OE33 M3\1OmN6fG:2b4jpZ4l1gSCjc4PhfS=> MonJO|IhcA>? NEDGbIdKSzVyIE2gNE4zKM7:TR?= MmjKQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7MUW4OVEoRjF5OUG1PFUyRC:jPh?=
HepG2 Mn;kR5l1d3SxeHnjbZR6KGG|c3H5 M{OzXFczKGh? NEPYfGtKSzVyIE2gNE4{KM7:TR?= NF3LbW49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{mxOVg2OSd-MUe5NVU5PTF:L3G+
OE19 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MXq3NkBp MoWxTWM2OCB;IECuOEDPxE1? MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzlzNUi1NUc,OTd7MUW4OVE9N2F-
L12 MUfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MWq0PEBp MWPJR|UxKD1iMD6wNFYh|ryP M3foZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUezN|YyLz5zN{m3N|M3OTxxYU6=
NCI-H460 NIHuZ2FEgXSxdH;4bYNqfHliYYPzZZk> MYq0PEBp M2W2WGlEPTBiPTCwMlAyKM7:TR?= NWDzNJg2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5O|M{PjFpPkG3PVc{OzZzPD;hQi=>
SKOV3 NXXz[VVTS3m2b4TvfIlkcXS7IHHzd4F6 NWXNeYJyPDhiaB?= MV7JR|UxKD1iMD6wNUDPxE1? M4LEeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUezN|YyLz5zN{m3N|M3OTxxYU6=
SF268 MoHRR5l1d3SxeHnjbZR6KGG|c3H5 M1Hwe|Q5KGh? NGLWTlRKSzVyIE2gNE4xOSEQvF2= NVm2dJhwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUe5O|M{PjFpPkG3PVc{OzZzPD;hQi=>
RKO M{nQcmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1L6W|Q5KGh? MoDETWM2OCB;IECuNFEh|ryP MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
KB/HeLa M2PhemN6fG:2b4jpZ4l1gSCjc4PhfS=> NYnMbZBYPDhiaB?= M162cWlEPTBiPTCwMlAyKM7:TR?= M2j1bVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF5OUezN|YyLz5zN{m3N|M3OTxxYU6=
P388 M4LwNWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MX:0PEBp MmOwTWM2OCB;IECuNFQh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
cells assessed as accumulation at G2/M phase after 24 hrs by flow cytometric analysis M2DMVWNmdGxiY4njcIUh[XK{ZYP0JIF{e2G7 NYHuW|JbTUN3MDC9JFAvODR7IN88US=> MlnVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTd7N{OzOlEoRjF5OUezN|YyRC:jPh?=
L1210 MUDBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M{LBb|Q5KGh? M1\qd2lEPTBiPTCwMlA3KM7:TR?= MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yPzl5M{O2NUc,OTd7N{OzOlE9N2F-
cells after 48 hrs by XTT assay NXnzWJNvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWnaTId1UUN3MDC9JFAvPCEQvF2= NIrXVGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zN{m3N|M3OSd-MUe5O|M{PjF:L3G+
A2780 NWPy[2hQS3m2b4TvfIlkcXS7IHHzd4F6 MX7JR|UxKD1iMD6wNFY{KM7:TR?= NFq1PZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOECwNVA5Pyd-MUiwNFExQDd:L3G+
BGC823 M2LQUGN6fG:2b4jpZ4l1gSCjc4PhfS=> MWXJR|UxKD1iMD6wNFch|ryP NIjTWXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOECwNVA5Pyd-MUiwNFExQDd:L3G+
A549 MlXGR5l1d3SxeHnjbZR6KGG|c3H5 MlfRTWM2OCB;IECuNFE6KM7:TR?= MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDByMUC4O{c,OThyMEGwPFc9N2F-
HCT8 MmG5R5l1d3SxeHnjbZR6KGG|c3H5 NITPOXpKSzVyIE2gNE4xOzdizszN MlzrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyMEGwPFcoRjF6MECxNFg4RC:jPh?=
Bel7402 NVziOWNCS3m2b4TvfIlkcXS7IHHzd4F6 NYHTT3ZnUUN3MDC9JFAvOSEQvF2= MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDByMUC4O{c,OThyMEGwPFc9N2F-
cells by alamar blue assay NXzN[ZFKTnWwY4Tpc44h[XO|YYm= MUjJR|UxKD1iMD6wOEDPxE1? MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDB5MEm2OUc,OThyN{C5OlU9N2F-
PANC1 NEjaPIdEgXSxdH;4bYNqfHliYYPzZZk> MlS1O|IhcA>? Mn25TWM2OCB;IECuNFA4KM7:TR?= M4riNlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MEixNlU4Lz5zOEC4NVI2PzxxYU6=
DLD1 NYT6d2c5S3m2b4TvfIlkcXS7IHHzd4F6 NV;nd4tIPzJiaB?= Mkf2TWM2OCB;IECuNFEyKM7:TR?= NWLCfod{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUiwPFEzPTdpPkG4NFgyOjV5PD;hQi=>
AsPC1 MV3DfZRwfG:6aXPpeJkh[XO|YYm= NVO5RmhbPzJiaB?= NWCycHY2UUN3MDC9JFAvODJizszN Mn\HQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOThyOEGyOVcoRjF6MEixNlU4RC:jPh?=
NCI/ADR NWfq[nJQS3m2b4TvfIlkcXS7IHHzd4F6 MlT1O|IhcA>? MVLJR|UxKD1iMTFOwG0> NGq4TGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEC4NVI2Pyd-MUiwPFEzPTd:L3G+
SK-BR3 Ml\aRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MUe5OkBp MlfiS2k2OCB;IE[uNUDPxE1? M1;sW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MU[0NlA2Lz5zOEG2OFIxPTxxYU6=
A2780 NWDtUolmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NIHVW5A6PiCq MoPUTWM2OCB;IECuNFI{PCEQvF2= MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF5N{CxOEc,OThzN{ewNVQ9N2F-
SNU398 NXHkUFFkSXCxcITvd4l{KGG|c3H5 MmH1NlQhcA>? MmHESWM2OCB;IECuNFEyKM7:TR?= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7N{[xOEc,OThzOUe2NVQ9N2F-
HCT116 MkL0RZBweHSxc3nzJIF{e2G7 NHXPPYMzPCCq NUj3UIVmTUN3MDC9JFAvODJ2IN88US=> NIfsV5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEG5O|YyPCd-MUixPVc3OTR:L3G+
T47D MnPNRZBweHSxc3nzJIF{e2G7 Ml;5NlQhcA>? MXHFR|UxKD1iMD6wN|Yh|ryP MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDF7N{[xOEc,OThzOUe2NVQ9N2F-
SJSA1 Ml7RR5l1d3SxeHnjbZR6KGG|c3H5 NGLwS5g3KGh? MXnJR|UxKD1iMD6wNFMzKM7:TR?= M{HHTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkSzOlk3Lz5zOEK0N|Y6PjxxYU6=
P388 NIT5OnNEgXSxdH;4bYNqfHliYYPzZZk> M3;Rc|czKGh? MUHJR|UxKD1iMD65N{DPxE1? M4O5VVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6MkixPVUzLz5zOEK4NVk2OjxxYU6=
HL60 M3PmO2N6fG:2b4jpZ4l1gSCjc4PhfS=> MkXOO|IhcA>? NXXwZmhKUUN3MDC9JFAvQTNizszN Mn;2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{OEG5OVIoRjF6MkixPVUzRC:jPh?=
Bel7402 Ml;PR5l1d3SxeHnjbZR6KGG|c3H5 NUj2UnF5OjRiaB?= NF[yVYlKSzVyIE2gNE46OyEQvF2= MnntQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{OEG5OVIoRjF6MkixPVUzRC:jPh?=
A549 MYrDfZRwfG:6aXPpeJkh[XO|YYm= NFrycZozPCCq MUfJR|UxKD1iMD65N{DPxE1? MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDJ6MUm1Nkc,OTh{OEG5OVI9N2F-
KB M2\0Z2N6fG:2b4jpZ4l1gSCjc4PhfS=> MVW0PEBp MU\JR|UxKD1iMD6wNFQzKM7:TR?= MlHVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh{OUW0PVAoRjF6Mkm1OFkxRC:jPh?=
KBV20C NFHybWtEgXSxdH;4bYNqfHliYYPzZZk> NV\JWoQyPDhiaB?= NV3qUZAyUUN3MDC9JFEvPDRizszN M4\iOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6Mkm1OFkxLz5zOEK5OVQ6ODxxYU6=
DU145 M4rwNWN6fG:2b4jpZ4l1gSCjc4PhfS=> NYXjepVOPzJiaB?= M4TGdmlEPTBiPTCwMlAxPSEQvF2= NIHJZos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEOwPFU3Pid-MUizNFg2PjZ:L3G+
HL60 MVXDfZRwfG:6aXPpeJkh[XO|YYm= M3zT[|czKGh? MV;JR|UxKD1iMD6wNFUh|ryP MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNyOEW2Okc,OTh|MEi1OlY9N2F-
MDA435 M3\tV2N6fG:2b4jpZ4l1gSCjc4PhfS=> NHXZdGw4OiCq MWDJR|UxKD1iMD6wNFUh|ryP MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNyOEW2Okc,OTh|MEi1OlY9N2F-
MESSA MYHDfZRwfG:6aXPpeJkh[XO|YYm= NV2wZ4FOPzJiaB?= MYXJR|UxKD1iMD6wNFUh|ryP NXjlNIxYRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNFg2PjZpPkG4N|A5PTZ4PD;hQi=>
P388 MnLHR5l1d3SxeHnjbZR6KGG|c3H5 NWTPSZJRPzJiaB?= NEXtcXVKSzVyIE2gNE4xOSEQvF2= NUm3bHNbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUizNFg2PjZpPkG4N|A5PTZ4PD;hQi=>
HL60/TX1000 Mlf6R5l1d3SxeHnjbZR6KGG|c3H5 M1XPVlczKGh? NVOxblNiUUN3MDC9JFUh|ryP M3fWN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6M{C4OVY3Lz5zOEOwPFU3PjxxYU6=
MESSA/DX5 NUTVZ3hzS3m2b4TvfIlkcXS7IHHzd4F6 MV23NkBp Mlz1TWM2OCB;IEWg{txO Ml\RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MEi1OlYoRjF6M{C4OVY3RC:jPh?=
K562 NX7CNXpGT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MY[3NkBp NHvzXXdKSzVyIE2gNE4xODB4IN88US=> MlnUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MUOzNFcoRjF6M{GzN|A4RC:jPh?=
KB3-1 MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NUHubod6PzJiaB?= NIHRbYNKSzVyIE2gNE4xODJizszN MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDNzM{OwO{c,OTh|MUOzNFc9N2F-
HepG2 MXrHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1XGOlczKGh? NHXFO2VKSzVyIE2gNE4xODdizszN MmHvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTh|MUOzNFcoRjF6M{GzN|A4RC:jPh?=
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MCF7 MWfDfZRwfG:6aXPpeJkh[XO|YYm= M3fQNlMh\GG7cx?= MY\JR|UxKD1iMD6wNVE4KM7:TR?= NInmToM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOESxPVE2PCd-MUi0NVkyPTR:L3G+
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Hep3B MYjDfZRwfG:6aXPpeJkh[XO|YYm= MUezJIRigXN? NHr6OlNKSzVyIE2gNE4yOyEQvF2= M1rBVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6NEG5NVU1Lz5zOESxPVE2PDxxYU6=
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A2780 NXfMOYRbS3m2b4TvfIlkcXS7IHHzd4F6 Mo\5O|IhcA>? NUHKW|ZuUUN3MDC9JFAvODBzM{ig{txO NYLH[Zd{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi0OlU5PDZpPkG4OFY2QDR4PD;hQi=>
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MCF7 NVT1TmlqT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3PiTlQ5KGh? M4q2b2dKPTBiPTCwMlA2PCEQvF2= NUL1fIY3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi1O|k{QDdpPkG4OVc6Ozh5PD;hQi=>
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HCT116 Ml3qR5l1d3SxeHnjbZR6KGG|c3H5 MojLTWM2OCB;IECuNFE{PiEQvF2= NGS0fW49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOE[wOlU1OCd-MUi2NFY2PDB:L3G+
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A549 M1LMcWN6fG:2b4jpZ4l1gSCjc4PhfS=> NF:0eWlKSzVyIE2gNE4xOjNzIN88US=> MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZyNkW0NEc,OTh4ME[1OFA9N2F-
MDA-MB-231 NVjwcYxXS3m2b4TvfIlkcXS7IHHzd4F6 M1jYRmlEPTBiPTCwMlA1ODVizszN MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZyNkW0NEc,OTh4ME[1OFA9N2F-
SF295 MWXDfZRwfG:6aXPpeJkh[XO|YYm= MXPJR|UxKD1iMD6yPUDPxE1? MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDZyNkW0NEc,OTh4ME[1OFA9N2F-
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Eca109 NXvXdGViS3m2b4TvfIlkcXS7IHHzd4F6 NX7SSng5UUN3MDC9JFIvPzNizszN NVjNVpoxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3NFEzQDFpPkG4O|AyOjhzPD;hQi=>
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HepG2 NYHWemdpSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MlS0OFghcA>? MYHJR|UxKD1iMD62NkDPxE1? M{Xq[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6N{CxN|AyLz5zOEewNVMxOTxxYU6=
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HCT116 NYH2flBRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NX\l[nVvPDhiaB?= MXLJR|UxKD1iNj6xPEDPxE1? MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDdyMUOwNUc,OTh5MEGzNFE9N2F-
A549 M2XUe2N6fG:2b4jpZ4l1gSCjc4PhfS=> NV;KdlJvUUN3MDC9JFAvODB{IN88US=> NILjcos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEexOVc5Oid-MUi3NVU4QDJ:L3G+
CCRF-CEM Mlu5R5l1d3SxeHnjbZR6KGG|c3H5 MnXGO|IhcA>? Mk\GTWM2OCB;IECuNFAyOSEQvF2= NVfGb3FkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi3OVI5PjlpPkG4O|UzQDZ7PD;hQi=>
SKOV3 NFryclFCdnSrY3HuZ4VzKGG|c3H5 MlTMO|IhcA>? Ml;yTWM2OCB;IECuNFAyOzRizszN MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDd4MkO1PEc,OTh5NkKzOVg9N2F-
MCF7 MWDDfZRwfG:6aXPpeJkh[XO|YYm= M3yyW2VFPTBiPTCwMlAxOzJizszN MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl{NkewNUc,OTh7Mk[3NFE9N2F-
NCI/ADR-RES NF;jWXdEgXSxdH;4bYNqfHliYYPzZZk> M4DlZWVFPTBiPTCxMlUh|ryP MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl{NkewNUc,OTh7Mk[3NFE9N2F-
PANC1 NUDZVYZ7S3m2b4TvfIlkcXS7IHHzd4F6 NVXBe21mPzJiaB?= NHrtdpBKSzVyIE2gNE4xODl7IN88US=> MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl3MUe4O{c,OTh7NUG3PFc9N2F-
DLD1 MlXER5l1d3SxeHnjbZR6KGG|c3H5 NVfXVmVJPzJiaB?= NGLLTo1KSzVyIE2gNE4xOjJizszN M2fpOlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUWxO|g4Lz5zOEm1NVc5PzxxYU6=
AsPC1 Mn;pR5l1d3SxeHnjbZR6KGG|c3H5 M3jjZlczKGh? NH3tfVNKSzVyIE2gNE4xQDlizszN M1jCXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUWxO|g4Lz5zOEm1NVc5PzxxYU6=
NCI/ADR-RES Ml[0R5l1d3SxeHnjbZR6KGG|c3H5 M2npbFczKGh? NGe0Xo1KSzVyIE2gNU4{KM7:TR?= NVfSdZFMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5OVE4QDdpPkG4PVUyPzh5PD;hQi=>
MCF7 M2LwO2N6fG:2b4jpZ4l1gSCjc4PhfS=> MoTYSWQ2OCB;IECuNFAzOSEQvF2= NIfwdIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOEm3O|Y2QSd-MUi5O|c3PTl:L3G+
NCI/ADR-RES MYTDfZRwfG:6aXPpeJkh[XO|YYm= NH3nWZlGTDVyIE2gNkDPxE1? MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl5N{[1PUc,OTh7N{e2OVk9N2F-
A431 NFXWTFREgXSxdH;4bYNqfHliYYPzZZk> MXi3NkBp M2TWV2lEPTBiPTCwMlAzPTFizszN NVvZeJVDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5PVA2PzRpPkG4PVkxPTd2PD;hQi=>
MCF7 NXzTVXhNS3m2b4TvfIlkcXS7IHHzd4F6 M2LUdVczKGh? MmfiTWM2OCB;IECuNFM6KM7:TR?= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQDl7MEW3OEc,OTh7OUC1O|Q9N2F-
MDA-MB-231 MYTDfZRwfG:6aXPpeJkh[XO|YYm= MYW3NkBp MnTpTWM2OCB;IECuNFQ4OSEQvF2= NYTtdlFuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUi5PVA2PzRpPkG4PVkxPTd2PD;hQi=>
SKOV3 MoH5R5l1d3SxeHnjbZR6KGG|c3H5 NGrDOHM4OiCq MYLJR|UxKD1iMD6wOlU5KM7:TR?= M2C2RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF6OUmwOVc1Lz5zOEm5NFU4PDxxYU6=
PANC1 MnO0S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGHBe3g4OiCq NIXQPWlKSzVyIE2gNE4xODl7IN88US=> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB{Mk[3PUc,OTlyMkK2O|k9N2F-
DLD1 MUfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MXi3NkBp Mnq5TWM2OCB;IECuNFIzKM7:TR?= MkTpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyMkK2O|koRjF7MEKyOlc6RC:jPh?=
AsPC1 NWC5fo1WT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXnJXpR7PzJiaB?= NGDrflRKSzVyIE2gNE4xQDlizszN MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB{Mk[3PUc,OTlyMkK2O|k9N2F-
NCI/ADR M4faOWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MV:3NkBp MXvJR|UxKD1iMT6zJO69VQ>? MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB{Mk[3PUc,OTlyMkK2O|k9N2F-
A2780 NELQbG1CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1HzRlIh\GG7cx?= MVXJR|UxKD1iMD6wNlM1KM7:TR?= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB{OEGwNkc,OTlyMkixNFI9N2F-
KB M{\5TmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 Mn\KN{Bl[Xm| M2LqNWlEPTBiPTCwMlAxOjVizszN M3zWSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MESxNlQ4Lz5zOUC0NVI1PzxxYU6=
COLO205 NYrG[ZpVSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M1fo[lI1KGh? NV3GZoFSUUN3MDC9JFAvODB|MzFOwG0> MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB2MUK0O{c,OTlyNEGyOFc9N2F-
KB 8.5 NF3GPWZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1zHfFMh\GG7cx?= MX\JR|UxKD1iMD6wNlYh|ryP MnrXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNEGyOFcoRjF7MESxNlQ4RC:jPh?=
KBV1 NYPBbIRnSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NES0S|Q{KGSjeYO= NVfKV21XUUN3MDC9JFIvODF|IN88US=> NHnhSHk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC0NVI1Pyd-MUmwOFEzPDd:L3G+
KB M4Xpcmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWK3NkBp NHzvRm9KSzVyIE2gNE4xODN|IN88US=> NYqwWZl[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4PzNpPkG5NFU{Pzd|PD;hQi=>
KB-7D NYrFWJZ4T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{X2WlczKGh? M2HIR2lEPTBiPTCwMlAxPzlizszN NEjtUFg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c4Oyd-MUmwOVM4PzN:L3G+
Pgp170 overexpressing multidrug resistant-KB-TAX50 NU\Q[5JCT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV7DZWhTPzJiaB?= M1fSVWlEPTBiPTCwMlI4OyEQvF2= Mke5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3O|MoRjF7MEWzO|c{RC:jPh?=
NPC-TW01 MXrDfZRwfG:6aXPpeJkh[XO|YYm= MmWxO|IhcA>? NIOxbFBKSzVyIE2gNE4xODZizszN Mm\BQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3PFEoRjF7MEWzO|gyRC:jPh?=
MES-SA MluwR5l1d3SxeHnjbZR6KGG|c3H5 NGXvSFg4OiCq Mon6TWM2OCB;IECuNFA5KM7:TR?= M13L[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|gyLz5zOUC1N|c5OTxxYU6=
NCI-H838 MY\DfZRwfG:6aXPpeJkh[XO|YYm= NED2cWg4OiCq MXfJR|UxKD1iMD6wNlYh|ryP NVnZfZkyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4QDFpPkG5NFU{PzhzPD;hQi=>
HCT116 MYPDfZRwfG:6aXPpeJkh[XO|YYm= MlvaO|IhcA>? NWrtbIJjUUN3MDC9JFAvODZzIN88US=> MmPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyNUO3PFEoRjF7MEWzO|gyRC:jPh?=
cells after 72 hrs by MTT assay NF[3dIJEgXSxdH;4bYNqfHliYYPzZZk> MmnyTWM2OCB;IEWuNVQh|ryP NYLrTml{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwOVM4QDFpPkG5NFU{PzhzPD;hQi=>
Hep3B M2jNcGN6fG:2b4jpZ4l1gSCjc4PhfS=> NF76[5A4OiCq M1jMVmlEPTBiPTC3MlI3KM7:TR?= M13Hc|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEWzO|gyLz5zOUC1N|c5OTxxYU6=
A498 MWfDfZRwfG:6aXPpeJkh[XO|YYm= NHvqR5A4OiCq M1HXNGlEPTBiPTC4MlgyKM7:TR?= NIDEd4w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC1N|c5OSd-MUmwOVM4QDF:L3G+
NB4 MXrDfZRwfG:6aXPpeJkh[XO|YYm= MVy0PEBp M3rK[mlEPTBiPTCwMlEh|ryP NHvHeW89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
A549 NEXmXlJEgXSxdH;4bYNqfHliYYPzZZk> MWW0PEBp NFrDb5lKSzVyIE2gNE4yKM7:TR?= M{\SfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEeyNlA6Lz5zOUC3NlIxQTxxYU6=
MCF7 NX;NcoFMS3m2b4TvfIlkcXS7IHHzd4F6 M4LnV|Q5KGh? MmXQTWM2OCB;IECuNUDPxE1? Ml7mQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyN{KyNFkoRjF7MEeyNlA6RC:jPh?=
SH-SY5Y M{ThWWN6fG:2b4jpZ4l1gSCjc4PhfS=> NV\nWFU1PDhiaB?= M1vTSmlEPTBiPTCwMlIh|ryP NWPwZZNQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwO|IzODlpPkG5NFczOjB7PD;hQi=>
PC3 M4i1NGN6fG:2b4jpZ4l1gSCjc4PhfS=> M2jWWVQ5KGh? MVrJR|UxKD1iMD6yJO69VQ>? NG[zZWY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUC3NlIxQSd-MUmwO|IzODl:L3G+
DLD1 Mm\xR5l1d3SxeHnjbZR6KGG|c3H5 NHXqb4I4OiCq MoXnS2k2OCB;IECuNFEh|ryP MonwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlyOEGyOFkoRjF7MEixNlQ6RC:jPh?=
B16 NIrnPHdEgXSxdH;4bYNqfHliYYPzZZk> MmP0O|IhcA>? NILGdHlIUTVyIE2gNE4xOSEQvF2= M2fKVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
A172 NV\2fm1US3m2b4TvfIlkcXS7IHHzd4F6 MnTGO|IhcA>? NIL6VIVIUTVyIE2gNE4xOSEQvF2= MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB6MUK0PUc,OTlyOEGyOFk9N2F-
HeLa MnzRR5l1d3SxeHnjbZR6KGG|c3H5 NH;RZ2w4OiCq NF;O[XVIUTVyIE2gNE4xOiEQvF2= NXrkVY5zRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmwPFEzPDlpPkG5NFgyOjR7PD;hQi=>
U87 MUHDfZRwfG:6aXPpeJkh[XO|YYm= MUK3NkBp M{HOXGdKPTBiPTCwMlAzKM7:TR?= M3HjPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEixNlQ6Lz5zOUC4NVI1QTxxYU6=
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HeLa MlS5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NILXRpM6PiCq NI\nSFFKSzVyIE2gNE4xODFizszN M4\PS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MEmxOVc6Lz5zOUC5NVU4QTxxYU6=
SKOV3 MWnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NFjDVY06PiCq Mm\WTWM2OCB;IECuNFE3KM7:TR?= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB7MUW3PUc,OTlyOUG1O|k9N2F-
BGC823 M3z2[mFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NF[1VIg6PiCq MkntTWM2OCB;IECuNFE5QSEQvF2= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTB7MUW3PUc,OTlyOUG1O|k9N2F-
HCT116 MYrDfZRwfG:6aXPpeJkh[XO|YYm= NH;5Rno4OiCq NFrJ[5dKSzVyIE2gNE4xODFzIN88US=> MoTYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlzMkSyOVAoRjF7MUK0NlUxRC:jPh?=
CCRF-CEM NEnsV5FEgXSxdH;4bYNqfHliYYPzZZk> MkDJO|IhcA>? NVjKNotXUUN3MDC9JFAvODB|MTFOwG0> MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{NEK1NEc,OTlzMkSyOVA9N2F-
MX1 M3ri[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NW[wWGcyPzJiaB?= M33KVGlEPTBiPTCwMlA1PiEQvF2= MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{NEK1NEc,OTlzMkSyOVA9N2F-
HCT116 NWi4UGFSS3m2b4TvfIlkcXS7IHHzd4F6 NWr5RYZXPCCmYYnz NV\H[nJvUUN3MDC9JFAvODBzMTFOwG0> NFfQeow9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUGyPFE2Pid-MUmxNlgyPTZ:L3G+
HT-29 M1HjR2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXj4dHNyPCCmYYnz NYG5WnFkUUN3MDC9JFAvODB|NjFOwG0> MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF{OEG1Okc,OTlzMkixOVY9N2F-
A2780 NGr2TlhEgXSxdH;4bYNqfHliYYPzZZk> NFzIZ3o1QCCq NUfx[5VXUUN3MDC9JFAvODBzMzFOwG0> MkDkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTlzMki5O|IoRjF7MUK4PVczRC:jPh?=
KB MmfvS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NVnYXphkTUR3MDC9JFAvODJ|IN88US=> M4\vV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MU[xN|E3Lz5zOUG2NVMyPjxxYU6=
HepG2 NHjHeY1EgXSxdH;4bYNqfHliYYPzZZk> M{Xnb2dKPTBiPTCwMlAxOSEQvF2= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTF7NUmwNUc,OTlzOUW5NFE9N2F-
WI38 M{mxc2N6fG:2b4jpZ4l1gSCjc4PhfS=> M4HDemdKPTBiPTCwMlAyOzdizszN NE\UcZk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUG5OVkxOSd-MUmxPVU6ODF:L3G+
RKO MWfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? Mny3TWM2OCB;IECuNFIh|ryP MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
KB/HeLa NFqzfnBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NX34bVkzUUN3MDC9JFAvODNizszN Mo\uQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{MkCwNVgoRjF7MkKwNFE5RC:jPh?=
SKOV3 NWPDW3VUSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWXGSGVCUUN3MDC9JFAvODVizszN M1HC[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkKwNFE5Lz5zOUKyNFAyQDxxYU6=
SF268 NYeyTGJCSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Ml3yTWM2OCB;IECuNFUh|ryP M1XzcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkKwNFE5Lz5zOUKyNFAyQDxxYU6=
P388 M4PifWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MlXqOFghcA>? M3G2dmlEPTBiPTCwMlA2KM7:TR?= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
cells ectopic expression of human NHHYZWJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MYG0PEBp MWjJR|UxKD1iMD6wOUDPxE1? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ{MECxPEc,OTl{MkCwNVg9N2F-
L1210 MVnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MY[0PEBp MYPJR|UxKD1iMD6wOkDPxE1? NF7jfmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKyNFAyQCd-MUmyNlAxOTh:L3G+
NCI-H460 MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NHHKWW9KSzVyIE2gNE4xPyEQvF2= M{Tte|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkKwNFE5Lz5zOUKyNFAyQDxxYU6=
MkDQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MUe0PEBp MVfJR|UxKD1iMD6zJO69VQ>? NV;wUYRxRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyNlAxOThpPkG5NlIxODF6PD;hQi=>
MCF7 Mm\xR5l1d3SxeHnjbZR6KGG|c3H5 NUTKR|h6PzJiaB?= MWLJR|UxKD1iMD6wNFEzKM7:TR?= M{XOO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlQxLz5zOUKzPVI1ODxxYU6=
A2780 MlfrR5l1d3SxeHnjbZR6KGG|c3H5 NWHVXXhVPzJiaB?= MYTJR|UxKD1iMD6wNFE{QCEQvF2= Mof6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
wild type A2780 MkjHR5l1d3SxeHnjbZR6KGG|c3H5 MWe3NkBp M1TCOmlEPTBiPTCwMlAxOTdizszN MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ|OUK0NEc,OTl{M{myOFA9N2F-
cisplatin-resistant A2780 M2jCZmN6fG:2b4jpZ4l1gSCjc4PhfS=> MXe3NkBp M2fVTWlEPTBiPTCwMlAxOjJizszN MmnHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
LCC-6 MULDfZRwfG:6aXPpeJkh[XO|YYm= M1iz[FczKGh? NFPDTnFKSzVyIE2gNE4xODJ2NTFOwG0> NUX1Z5JKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
HT-29 NWnKfJBnS3m2b4TvfIlkcXS7IHHzd4F6 NVf5V5J7PzJiaB?= M4rUW2lEPTBiPTCwMlAxOzZizszN M3rIb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlQxLz5zOUKzPVI1ODxxYU6=
H460 NHnIXpREgXSxdH;4bYNqfHliYYPzZZk> MWC3NkBp MVvJR|UxKD1iMD6wNFQ6KM7:TR?= M1;pXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlQxLz5zOUKzPVI1ODxxYU6=
topotecan-resistant A2780 NIrPS4REgXSxdH;4bYNqfHliYYPzZZk> MWC3NkBp MVfJR|UxKD1iMD6wNFczKM7:TR?= MlXFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
PANC1 NV\i[Fg1S3m2b4TvfIlkcXS7IHHzd4F6 NFnlTnU4OiCq M{X3bWlEPTBiPTCwMlAzPTdizszN NGH6[pI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
1A9PTX22 M2ixcmN6fG:2b4jpZ4l1gSCjc4PhfS=> NV3ycJg6PzJiaB?= MWHJR|UxKD1iMD6xOlA4KM7:TR?= NEC3THg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUKzPVI1OCd-MUmyN|kzPDB:L3G+
NCI/ADR NXLIeXpxS3m2b4TvfIlkcXS7IHHzd4F6 NHXSRpM4OiCq NH\IcZVKSzVyIE2gNE4{KM7:TR?= NVWxbFRGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
A2780 M{nyXmZ2dmO2aX;uJIF{e2G7 MkDuTWM2OCB;IECuN|g3KM7:TR?= NU[1fZdURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyN|kzPDBpPkG5NlM6OjRyPD;hQi=>
1A9PTX10 MX;DfZRwfG:6aXPpeJkh[XO|YYm= M{PDZlczKGh? NVq4Soc3UUN3MDC9JFAvPTN{OUWg{txO M2j0V|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkO5NlQxLz5zOUKzPVI1ODxxYU6=
A2780/ADR MnjwR5l1d3SxeHnjbZR6KGG|c3H5 Mmr0O|IhcA>? MX3JR|UxKD1iMT6yN|kh|ryP MnXvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{M{myOFAoRjF7MkO5NlQxRC:jPh?=
A549 MUPDfZRwfG:6aXPpeJkh[XO|YYm= NWfLbXdyOjRiaB?= MlH2TWM2OCB;IECuNFA2OiEQvF2= M1KwUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkS1NlYyLz5zOUK0OVI3OTxxYU6=
PC3M NUfzUIpHS3m2b4TvfIlkcXS7IHHzd4F6 MXmyOEBp M{fqcGlEPTBiPTCwMlAzPyEQvF2= NXfvSIZPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOFUzPjFpPkG5NlQ2OjZzPD;hQi=>
HCT8 M3qyWWN6fG:2b4jpZ4l1gSCjc4PhfS=> MkXwNlQhcA>? M4jncGlEPTBiPTCwMlA{PyEQvF2= MojpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl{NEWyOlEoRjF7MkS1NlYyRC:jPh?=
Bel7402 MX\DfZRwfG:6aXPpeJkh[XO|YYm= MXWyOEBp NYrTWpkxUUN3MDC9JFAvODl3IN88US=> NULjXI5QRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmyOFUzPjFpPkG5NlQ2OjZzPD;hQi=>
A2780 MWrDfZRwfG:6aXPpeJkh[XO|YYm= M4rQc2lEPTBiPTCwMlAyPCEQvF2= M3PRblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkiyNVg3Lz5zOUK4NlE5PjxxYU6=
SNU398 NF6wXohCeG:ydH;zbZMh[XO|YYm= NYjKcItUPDhiaB?= M2\6N2dKPTBiPTCwMlAyKM7:TR?= M4nDUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkiyNVg5Lz5zOUK4NlE5QDxxYU6=
HCT116 M1\6cGFxd3C2b4Ppd{Bie3OjeR?= MWS0PEBp NX7meZZrTUN3MDC9JFAvODJ|IN88US=> M{jsVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7MkiyNVg5Lz5zOUK4NlE5QDxxYU6=
T47D Mlv5RZBweHSxc3nzJIF{e2G7 NFXiOHk1QCCq NV2xSWNGTUN3MDC9JFAvODN3IN88US=> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTJ6MkG4PEc,OTl{OEKxPFg9N2F-
PC3 NUnwfnRsS3m2b4TvfIlkcXS7IHHzd4F6 NXvMRndnPCCmYYnz MlfzTWM2OCB;IECuNFAyPCEQvF2= Ml7TQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl|NUmxOlkoRjF7M{W5NVY6RC:jPh?=
A2780 MonUR5l1d3SxeHnjbZR6KGG|c3H5 MnXVOEBl[Xm| NITleotKSzVyIE2gNE4xOTR7IN88US=> MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN3OUG2PUc,OTl|NUmxOlk9N2F-
K562 M1PRfGN6fG:2b4jpZ4l1gSCjc4PhfS=> MX:0PEBp MojwTWM2OCB;IEGuNVYh|ryP NInKOWg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUO1PVE5PSd-MUmzOVkyQDV:L3G+
MCF7 NELCWGxEgXSxdH;4bYNqfHliYYPzZZk> NULMfYU6PDhiaB?= NF[1eoZKSzVyIE2gNk4yOSEQvF2= NUjtdHJuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmzOVkyQDVpPkG5N|U6OTh3PD;hQi=>
A549 MnmwR5l1d3SxeHnjbZR6KGG|c3H5 NVHl[YRUPDhiaB?= NGnXTJVKSzVyIE2gNk41PiEQvF2= NIr2cIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUO1PVE5PSd-MUmzOVkyQDV:L3G+
SGC NVi3NGY{S3m2b4TvfIlkcXS7IHHzd4F6 NXH6TWVbPDhiaB?= Mlf1TWM2OCB;IEOuN|Qh|ryP NFnzNXo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUO1PVE5PSd-MUmzOVkyQDV:L3G+
HCT116 NFfqdodEgXSxdH;4bYNqfHliYYPzZZk> NHGwNnA1QCCq NVPJXYVnUUN3MDC9JFQvOzdizszN NWjYZlM5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUmzOVkyQDVpPkG5N|U6OTh3PD;hQi=>
A431 M4raXGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M{j4V2dKPTBiPTCwMlAxODBzIN88US=> MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTN7NEKxPEc,OTl|OUSyNVg9N2F-
MESSA NIDjSYpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MV\HTVUxKD1iMD6wNFAxOSEQvF2= M3nVdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{m0NlE5Lz5zOUO5OFIyQDxxYU6=
HCT15 MV3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NIHUTlNIUTVyIE2gNE4xOTFizszN M4nHcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{m0NlE5Lz5zOUO5OFIyQDxxYU6=
MES-SA/Dx5 MVTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M3vTcmdKPTBiPTCwMlE3KM7:TR?= M1[5UlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{m0NlE5Lz5zOUO5OFIyQDxxYU6=
HCT15/CLO2 M3HCeGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NVnHfJhlT0l3MDC9JFAvQDNizszN M2LNUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7M{m0NlE5Lz5zOUO5OFIyQDxxYU6=
wild type A2780 NWrBPZl5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MXy3NkBp M1fxRmlEPTBiPTCwMlAxOTdizszN NHTjWmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyN|M1OCd-MUm0NlM{PDB:L3G+
cisplatin-resistant A2780 NFPyUZRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUm3NkBp NE[zSmVKSzVyIE2gNE4xODJ{IN88US=> MlPjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2MkOzOFAoRjF7NEKzN|QxRC:jPh?=
topotecan-resistant A2780 M3\US2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mnv3O|IhcA>? NIDWTphKSzVyIE2gNE4xODd{IN88US=> Mni2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2MkOzOFAoRjF7NEKzN|QxRC:jPh?=
adriamycin and doxorubicin-resistant A2780 NVz0UolxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NXf2bGczPzJiaB?= M3rpfWlEPTBiPTCxMlI{QSEQvF2= NGXFcHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyN|M1OCd-MUm0NlM{PDB:L3G+
paclitaxel-resistant A2780TC1 MWnGeY5kfGmxbjDhd5NigQ>? M1XFe2lEPTBiPTC1Mlg6QCEQvF2= NV3kPVZLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlM{PDBpPkG5OFI{OzRyPD;hQi=>
NB4 NEL5WWtEgXSxdH;4bYNqfHliYYPzZZk> MU[0PEBp Ml22TWM2OCB;IECuNUDPxE1? M4XUfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7NEK1OVg6Lz5zOUSyOVU5QTxxYU6=
A549 MYTDfZRwfG:6aXPpeJkh[XO|YYm= NED4ZoE1QCCq M3fWdmlEPTBiPTCwMlEh|ryP NX[0dHF7RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm0NlU2QDlpPkG5OFI2PTh7PD;hQi=>
MCF7 NYjFVmFLS3m2b4TvfIlkcXS7IHHzd4F6 NGT6ZnM1QCCq MX\JR|UxKD1iMD6xJO69VQ>? NFn5Z449[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUSyOVU5QSd-MUm0NlU2QDl:L3G+
SH-SY5Y NX3I[Gw1S3m2b4TvfIlkcXS7IHHzd4F6 NUO1OphVPDhiaB?= NH\oV3NKSzVyIE2gNE4zKM7:TR?= MkD2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl2MkW1PFkoRjF7NEK1OVg6RC:jPh?=
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HCT116 NUXzNnIyS3m2b4TvfIlkcXS7IHHzd4F6 M4S0fFczKGh? NFP6fmRKSzVyIE2gNE4xODFzIN88US=> MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTV5Nke4OUc,OTl3N{[3PFU9N2F-
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vinblastine-resistant CCRF-CEM MlqxR5l1d3SxeHnjbZR6KGG|c3H5 MWS3NkBp M4TWdmlEPTBiPTCwMlQh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTV5Nke4OUc,OTl3N{[3PFU9N2F-
taxol-resistant CCRF-CEM NWDxOok5S3m2b4TvfIlkcXS7IHHzd4F6 NWrCXIRuPzJiaB?= NFfkbpJKSzVyIE2gNU4zKM7:TR?= NITtV|I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9zOUW3Olc5PSd-MUm1O|Y4QDV:L3G+
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MES-SA/Dx5 NUjEWHVzS3m2b4TvfIlkcXS7IHHzd4F6 MV3JR|UxKD1iNz61N|gh|ryP M{CwOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7Nke5OFc2Lz5zOU[3PVQ4PTxxYU6=
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A2780 NVvONlJoS3m2b4TvfIlkcXS7IHHzd4F6 NHnBXYRKSzVyIE2gNE4xODd7IN88US=> NVL6cVZQRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3NFg3PzlpPkG5O|A5Pjd7PD;hQi=>
Bel7404 MkXCR5l1d3SxeHnjbZR6KGG|c3H5 MVrJR|UxKD1iMD6wNVI{KM7:TR?= NWfzWVJDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3NFg3PzlpPkG5O|A5Pjd7PD;hQi=>
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MUTU-I M1HRTGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M4mxSFI1KGh? MkXYTWM2OCB;IECuNFEh|ryP M1;pe|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzF7N{G3NlE2Lz5zOUexO|IyPTxxYU6=
HCT116 MlT0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Mn3ZO|IhcA>? MXHJR|UxKD1iMD6wNFEh|ryP MUK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2M{i2N{c,OTl5NEO4OlM9N2F-
SW48 MkD1RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MVO3NkBp NFL1eGZKSzVyIE2gNE4xODFizszN MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2M{i2N{c,OTl5NEO4OlM9N2F-
MES-SA NWPRbmZjSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Ml7xO|IhcA>? NXj3fJNVUUN3MDC9JFAvODBzIN88US=> NVzBcmx6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMUm3OFM5PjNpPkG5O|Q{QDZ|PD;hQi=>
CEM NGDFW3pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NWT2dVJjPzJiaB?= NYrlOpY1UUN3MDC9JFAvODB{IN88US=> MlvoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOTl5NEO4OlMoRjF7N{SzPFY{RC:jPh?=
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MCF7 NVW5cI5iS3m2b4TvfIlkcXS7IHHzd4F6 M1LaTFczKGh? NXTDS21PUUN3MDC9JFAvODB|IN88US=> MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8yQTd2M{i2N{c,OTl5NEO4OlM9N2F-
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Bel7402 M3fnUmN6fG:2b4jpZ4l1gSCjc4PhfS=> MUezJIRigXN? MnHuTWM2OCB;IEGuPEDPxE1? NFS0RYI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEW5N|g{QSd-MkC1PVM5Ozl:L3G+
KB NFrKT3REgXSxdH;4bYNqfHliYYPzZZk> NHWxU3BKSzVyIE2gNE4xQCEQvF2= NFjPVII9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{ME[yO|czOSd-MkC2Nlc4OjF:L3G+
786-0 M2jnRmN6fG:2b4jpZ4l1gSCjc4PhfS=> M{TiVWlEPTBiPTCwMlA5KM7:TR?= MlXHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB4Mke3NlEoRjJyNkK3O|IyRC:jPh?=
HepG2 NI\mSYFEgXSxdH;4bYNqfHliYYPzZZk> NXTpNGZEUUN3MDC9JFAvODhizszN M{jBb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNkK3O|IyLz5{ME[yO|czOTxxYU6=
OS-RC2 NWTn[3huS3m2b4TvfIlkcXS7IHHzd4F6 NHX1fmJKSzVyIE2gNE4xQCEQvF2= NGXNWXE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{ME[yO|czOSd-MkC2Nlc4OjF:L3G+
22Rv1 MWXDfZRwfG:6aXPpeJkh[XO|YYm= MkHuTWM2OCB;IECuNFgh|ryP NHjLO|A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{ME[yO|czOSd-MkC2Nlc4OjF:L3G+
HT-29 MXPDfZRwfG:6aXPpeJkh[XO|YYm= M2C1R2lEPTBiPTCwMlM5KM7:TR?= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODZ{N{eyNUc,OjB4Mke3NlE9N2F-
A375 MXfDfZRwfG:6aXPpeJkh[XO|YYm= MlX6TWM2OCB;IECuPFEh|ryP MknVQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB4Mke3NlEoRjJyNkK3O|IyRC:jPh?=
MCF7 NXzVR3hvS3m2b4TvfIlkcXS7IHHzd4F6 NUfjSYc{UUN3MDC9JFEvOyEQvF2= MlrQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB4Mke3NlEoRjJyNkK3O|IyRC:jPh?=
BCG823 NHLnPGpEgXSxdH;4bYNqfHliYYPzZZk> NWXkN2w1UUN3MDC9JFEvPSEQvF2= M2TXSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyNkK3O|IyLz5{ME[yO|czOTxxYU6=
769-P MkDnR5l1d3SxeHnjbZR6KGG|c3H5 M{PCRWlEPTBiPTC3MlEh|ryP MlLOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB4Mke3NlEoRjJyNkK3O|IyRC:jPh?=
KB NVP0[3FSS3m2b4TvfIlkcXS7IHHzd4F6 M1TJfGlEPTBiPTCwMlA5KM7:TR?= NIXtXJQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexOlQ3QCd-MkC3NVY1Pjh:L3G+
786-0 M4PPbmN6fG:2b4jpZ4l1gSCjc4PhfS=> NWTJb2tkUUN3MDC9JFAvODhizszN NIq2UFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexOlQ3QCd-MkC3NVY1Pjh:L3G+
OS-RC2 M{fSRWN6fG:2b4jpZ4l1gSCjc4PhfS=> NH7ufVJKSzVyIE2gNE4xQCEQvF2= NFvtXnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexOlQ3QCd-MkC3NVY1Pjh:L3G+
22Rv1 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NGjlR3RKSzVyIE2gNE4xQCEQvF2= NFTrbZE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexOlQ3QCd-MkC3NVY1Pjh:L3G+
HepG2 Mom4R5l1d3SxeHnjbZR6KGG|c3H5 NWrI[|VLUUN3MDC9JFAvODhizszN MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODdzNkS2PEc,OjB5MU[0Olg9N2F-
HT-29 MmLRR5l1d3SxeHnjbZR6KGG|c3H5 M1nVcGlEPTBiPTCwMlM5KM7:TR?= M1nab|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{G2OFY5Lz5{MEexOlQ3QDxxYU6=
A375 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NV;rfmNtUUN3MDC9JFAvQDFizszN Mom4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5MU[0OlgoRjJyN{G2OFY5RC:jPh?=
MCF7 NYnQ[XRkS3m2b4TvfIlkcXS7IHHzd4F6 NGH5THNKSzVyIE2gNU4{KM7:TR?= MYG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODdzNkS2PEc,OjB5MU[0Olg9N2F-
BGC823 NE\jemREgXSxdH;4bYNqfHliYYPzZZk> NYTEZ2dXUUN3MDC9JFEvPSEQvF2= M{L0RVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyN{G2OFY5Lz5{MEexOlQ3QDxxYU6=
769-P MofpR5l1d3SxeHnjbZR6KGG|c3H5 MoHITWM2OCB;IEeuNUDPxE1? NITuSoM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexOlQ3QCd-MkC3NVY1Pjh:L3G+
BGC823 M4PHbGN6fG:2b4jpZ4l1gSCjc4PhfS=> M13KZVczKGh? NVfhR5RuUUN3MDC9JFAvODBzIN88US=> NIDqT5Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexPVUyOCd-MkC3NVk2OTB:L3G+
A2780 M1;K[2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mn;JO|IhcA>? MnTmTWM2OCB;IECuNFAyKM7:TR?= MofaQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5MUm1NVAoRjJyN{G5OVExRC:jPh?=
A549 MULDfZRwfG:6aXPpeJkh[XO|YYm= M33q[FczKGh? MoTGTWM2OCB;IECuNFE3KM7:TR?= NHiyNGE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEexPVUyOCd-MkC3NVk2OTB:L3G+
HCT8 MoLnR5l1d3SxeHnjbZR6KGG|c3H5 NF\UPIk4OiCq MkX3TWM2OCB;IECuNFUyKM7:TR?= Ml;jQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5MUm1NVAoRjJyN{G5OVExRC:jPh?=
Bel7402 MWDDfZRwfG:6aXPpeJkh[XO|YYm= M4fCc|czKGh? M4TmXGlEPTBiPTCwMlA3KM7:TR?= MmfsQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5MUm1NVAoRjJyN{G5OVExRC:jPh?=
A549 MVvDfZRwfG:6aXPpeJkh[XO|YYm= NYO5dVk5PzJiaB?= MlvCTWM2OCB;IECuNFA{QCEQvF2= MoTQQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5M{K4NFkoRjJyN{OyPFA6RC:jPh?=
HEK NYfOfmdXS3m2b4TvfIlkcXS7IHHzd4F6 M4HmWVczKGh? NY\yO|c5UUN3MDC9JFAvODB|OTFOwG0> MVm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODd|MkiwPUc,OjB5M{K4NFk9N2F-
MCF7 NHn0bXVEgXSxdH;4bYNqfHliYYPzZZk> M1\PS|czKGh? M4TlTmlEPTBiPTCwMlAxPDRizszN MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODd|MkiwPUc,OjB5M{K4NFk9N2F-
HeLa M4jzeGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVXmN5I{PzJiaB?= MYDJR|UxKD1iMD6wNFg6KM7:TR?= MnW5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5M{K4NFkoRjJyN{OyPFA6RC:jPh?=
Hep3B MmXoRY51cWOjbnPldkBie3OjeR?= NFzFb2I{KGSjeYO= NYLTbVB7T0l3MDC9JFAvODByNDFOwG0> NUTTdYFHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3N|UyPDBpPkKwO|M2OTRyPD;hQi=>
DU145 NInMdnNEgXSxdH;4bYNqfHliYYPzZZk> Ml;jSWQ2OCB;IECuNFA{KM7:TR?= NGfjbYE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEezPFExOyd-MkC3N|gyODN:L3G+
KB Ml;ZR5l1d3SxeHnjbZR6KGG|c3H5 NGPiNoJGTDVyIE2gNE4xODdizszN MmnDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB5M{ixNFMoRjJyN{O4NVA{RC:jPh?=
A549 MofrR5l1d3SxeHnjbZR6KGG|c3H5 NFvIcopGTDVyIE2gNE4xODhizszN NYSwUFZWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC3N|gyODNpPkKwO|M5OTB|PD;hQi=>
MCF7 NV7RPI1mS3m2b4TvfIlkcXS7IHHzd4F6 M4HaXFczKGh? M2\rR2lEPTBiPTCwMlAxOiEQvF2= M3r1dFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOECwOVAxLz5{MEiwNFUxODxxYU6=
wild type LCC-6 NIL2RpFEgXSxdH;4bYNqfHliYYPzZZk> M1zmZlczKGh? MlTsTWM2OCB;IECuNFA{KM7:TR?= NUjHOXFlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4NFA2ODBpPkKwPFAxPTByPD;hQi=>
A2780 M4D6dmN6fG:2b4jpZ4l1gSCjc4PhfS=> MWm3NkBp MUDJR|UxKD1iMD6wNkDPxE1? MnfGQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6MEC1NFAoRjJyOECwOVAxRC:jPh?=
CFPAC-1 NWH6Z5prS3m2b4TvfIlkcXS7IHHzd4F6 NUTZdFNYPzJiaB?= MoDxTWM2OCB;IECuNFQ4KM7:TR?= Mnn5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjB6MEC1NFAoRjJyOECwOVAxRC:jPh?=
multidrug-resistant LCC-6 NInQWI9EgXSxdH;4bYNqfHliYYPzZZk> MX63NkBp M1e3Z2lEPTBiPTCwMlM4QSEQvF2= NUHqc2EzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4NFA2ODBpPkKwPFAxPTByPD;hQi=>
NCI/ADR Ml64R5l1d3SxeHnjbZR6KGG|c3H5 NVP4NlBtPzJiaB?= MV\JR|UxKD1iMD60NUDPxE1? NXTCNVRTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC4NFA2ODBpPkKwPFAxPTByPD;hQi=>
multidrug-resistant MDA-MB-435/LCCMDR1 MVHDfZRwfG:6aXPpeJkh[XO|YYm= MXu0PEBp M4K3e2lEPTBiPTCwMlAxPCEQvF2= M{fvOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUG5O|IxLz5{MEmxPVczODxxYU6=
multidrug-resistant MDA-MB-435/LCCMDR1 MlHTSpVv[3Srb36gZZN{[Xl? NGrmbG5KSzVyIE2gNE4xPjl|IN88US=> M1TFbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUG5O|IxLz5{MEmxPVczODxxYU6=
MDA-MB-435 NFL3TotEgXSxdH;4bYNqfHliYYPzZZk> MW[0PEBp M2fCUmlEPTBiPTCwMlI4PyEQvF2= M2X3UVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUG5O|IxLz5{MEmxPVczODxxYU6=
LNCAP NEThcJlEgXSxdH;4bYNqfHliYYPzZZk> NX3uWZFkUUN3MDC9JFAvODJ{MzFOwG0> NEDGN3k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEmzOlg4PCd-MkC5N|Y5PzR:L3G+
HT-29 NVLPcIFzS3m2b4TvfIlkcXS7IHHzd4F6 NFvkWWQ{KGSjeYO= NXq3enVuTUR3MDC9JFAvODByNjFOwG0> NH7mbZo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEmzPVU1OCd-MkC5N|k2PDB:L3G+
HCT116 MVTHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkDiPVYhcA>? MXvJR|UxKD1iMD6wNFIh|ryP M1uyZ|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJyOUSzOFAyLz5{MEm0N|QxOTxxYU6=
HCT15 NWLrcJp[T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M4PjS|k3KGh? NYrO[GV1UUN3MDC9JFAvOTRizszN NIPqT4U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEm0N|QxOSd-MkC5OFM1ODF:L3G+
HeLa NF\2[3pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NH7HUVlKSzVyIE2gNE4xODF4IN88US=> NXTxOlViRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC5O|M1QDhpPkKwPVc{PDh6PD;hQi=>
SKOV3 MVHBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NXu3S5h4UUN3MDC9JFAvODB|IN88US=> MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zODl5M{S4PEc,OjB7N{O0PFg9N2F-
A549 NELqU4xCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3HB[|k3KGh? MU\JR|UxKD1iMD6wNFQ6KM7:TR?= NV\5Z2JsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkC5O|Q2ODVpPkKwPVc1PTB3PD;hQi=>
MCF7 NWfBUFBWSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M1jVVFk3KGh? MlL4TWM2OCB;IECuNFIyKM7:TR?= NFHGNYc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MEm3OFUxPSd-MkC5O|Q2ODV:L3G+
HT-29 Ml\IRY51cWOjbnPldkBie3OjeR?= MXHFSFUxKD1iMD6wNFAyKM7:TR?= NH\TToM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC2O|IxPid-MkGwOlczODZ:L3G+
K562 NUjYUXFYS3m2b4TvfIlkcXS7IHHzd4F6 M{DRZ|Q5KGh? M2XDTmlEPTBiPTCxMlE3KM7:TR?= NYXHOZJvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGwOlc6OzNpPkKxNFY4QTN|PD;hQi=>
MCF7 NH3BWGdEgXSxdH;4bYNqfHliYYPzZZk> MlKwOFghcA>? M3:2emlEPTBiPTCyMlEyKM7:TR?= M4TTN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzME[3PVM{Lz5{MUC2O|k{OzxxYU6=
A549 NULnemlzS3m2b4TvfIlkcXS7IHHzd4F6 M{XkfFQ5KGh? NH7ZdFNKSzVyIE2gNk41PiEQvF2= NFf2fIU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC2O|k{Oyd-MkGwOlc6OzN:L3G+
SGC MUHDfZRwfG:6aXPpeJkh[XO|YYm= Mm\ROFghcA>? M3zxNWlEPTBiPTCzMlM1KM7:TR?= NHi2VlA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC2O|k{Oyd-MkGwOlc6OzN:L3G+
HCT116 NIfDTFNEgXSxdH;4bYNqfHliYYPzZZk> NVTrTmZ4PDhiaB?= NHzSOGRKSzVyIE2gOE4{PyEQvF2= NILkWlM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUC2O|k{Oyd-MkGwOlc6OzN:L3G+
CCRF-CEM MmO5R5l1d3SxeHnjbZR6KGG|c3H5 MkXTO|IhcA>? NIfqNVJKSzVyIE2gNE4xODNizszN NGH2Z5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUGwOlM4Pyd-MkGxNFY{Pzd:L3G+
MCF7 NEL2[JBEgXSxdH;4bYNqfHliYYPzZZk> NYT4UpY4PzJiaB?= Mom4S2k2OCB;IECuNFA{KM7:TR?= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTFzNUKxNEc,OjFzMUWyNVA9N2F-
HT-29 NWfKO4tqS3m2b4TvfIlkcXS7IHHzd4F6 MoW5O|IhcA>? NEPjfYNIUTVyIE2gNE4xODNizszN NWPPVnZrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNVUzOTBpPkKxNVE2OjFyPD;hQi=>
K562 MVfDfZRwfG:6aXPpeJkh[XO|YYm= MWC3NkBp NFrENY5IUTVyIE2gNE4xODRizszN NYXYSnVKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNVUzOTBpPkKxNVE2OjFyPD;hQi=>
PC3 MkL5R5l1d3SxeHnjbZR6KGG|c3H5 M3jxO|czKGh? MkjES2k2OCB;IECuNFA1KM7:TR?= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTFzNUKxNEc,OjFzMUWyNVA9N2F-
MCF7 MX7DfZRwfG:6aXPpeJkh[XO|YYm= NGr6WJMzPCCq M2XW[2lEPTBiPTCwMlY{KM7:TR?= M{S3Z|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUG1NlEzLz5{MUGxOVIyOjxxYU6=
SMMC7721 M2HFemN6fG:2b4jpZ4l1gSCjc4PhfS=> M{fHNFI1KGh? NYGzWFRzUUN3MDC9JFEvPDJizszN M{K1cFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUG1NlEzLz5{MUGxOVIyOjxxYU6=
A2780 M132eWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXTIbYFuPDhidH:gO|IhcA>? MW\JR|UxKD1iMD6wNUDPxE1? Mn3QQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzMk[wNlcoRjJzMUK2NFI4RC:jPh?=
Jurkat NF;Ze5RE\WyuIHP5Z4xmKGG{cnXzeEBie3OjeR?= MkDHNlQhcA>? NVfwXGxRUUN3MDC9JFAvODFizszN NHvuPWs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUGyOlAzPyd-MkGxNlYxOjd:L3G+
HeLa NXnHRZd3S3m2b4TvfIlkcXS7IHHzd4F6 MX20PEB1dyB5MjDo MoTuTWM2OCB;IECuNFIh|ryP M1;YSlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMUK2NFI4Lz5{MUGyOlAzPzxxYU6=
SW620 NIS2[phEgXSxdH;4bYNqfHliYYPzZZk> MVG0PEB1dyB5MjDo M4L4R2lEPTBiPTCwMlA{KM7:TR?= NVjvU|VLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxNlYxOjdpPkKxNVI3ODJ5PD;hQi=>
HCT116 MYXDfZRwfG:6aXPpeJkh[XO|YYm= M4LoXFczKGh? MlnxTWM2OCB;IECuNFAyOyEQvF2= NEXFSWc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUG0OFc2Pid-MkGxOFQ4PTZ:L3G+
CCRF-CEM NH7iPYFEgXSxdH;4bYNqfHliYYPzZZk> MlrqO|IhcA>? MVnJR|UxKD1iMD6wNFMh|ryP NYfnSoZZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGxOFQ4PTZpPkKxNVQ1PzV4PD;hQi=>
MX1 MoXZR5l1d3SxeHnjbZR6KGG|c3H5 MmfKO|IhcA>? MWLJR|UxKD1iMD6wN|Uh|ryP MkG3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjFzNES3OVYoRjJzMUS0O|U3RC:jPh?=
chemoresistant DG75 NEfx[|REgXSxdH;4bYNqfHliYYPzZZk> Mme1O|IhcA>? NF\2RXpKSzVyIE2gNE4xOSEQvF2= MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTJ{N{ewNkc,OjF{Mke3NFI9N2F-
chemosensitive MUTU-I NVnFT3dyS3m2b4TvfIlkcXS7IHHzd4F6 M2fWXFI1KGh? NXPTTXlyUUN3MDC9JFAvODFizszN NWDjPFNDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGyNlc4ODJpPkKxNlI4PzB{PD;hQi=>
HT1080 NHPsbIdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NEj4fZY6PiCq MV\JR|UxKD1iMD6wNFEzKM7:TR?= NHjWXFQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
A549 NYe3[ohlSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NGfPflE6PiCq MUHJR|UxKD1iMD6wNFQ1KM7:TR?= M1O4PFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkm2OFY4Lz5{MUK5OlQ3PzxxYU6=
A375 MWXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? Mni0PVYhcA>? NYP4OWxNUUN3MDC9JFAvODB2NjFOwG0> NHHTNYk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
NCI-N87 MWrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MlPYPVYhcA>? MlG4TWM2OCB;IECuNFA2QSEQvF2= M16y[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzMkm2OFY4Lz5{MUK5OlQ3PzxxYU6=
MCF7 NHvoS|BCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MmnjPVYhcA>? NUfkSVdwUUN3MDC9JFAvODJyNTFOwG0> NUfYTXJKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGyPVY1PjdpPkKxNlk3PDZ5PD;hQi=>
HeLa MmDhRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MlroPVYhcA>? MnvRTWM2OCB;IECuNUDPxE1? NEDKfJk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
PANC1 MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NGXVdVU6PiCq NGq4[m1KSzVyIE2gNE4{QDRzIN88US=> NHzQN5E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
Bel7402 M{HieWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MXS5OkBp NE[0TmxKSzVyIE2gNE42Pzh{IN88US=> NIO3eo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlQ3Pyd-MkGyPVY1Pjd:L3G+
1A9 MmjxRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MlztN{Bl[Xm| MnXKSWQ2OCB;IECuNFAzODlizszN NH;Eb|M9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlU4QSd-MkGyPVY2Pzl:L3G+
A549 NWXpR4tPSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Mn;KN{Bl[Xm| MmTiSWQ2OCB;IECuNFAzPTZizszN MlTmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF{OU[1O|koRjJzMkm2OVc6RC:jPh?=
KB Mn;VRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MXqzJIRigXN? MWXFSFUxKD1iMD6wNFI5PyEQvF2= NHi1[Io9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlU4QSd-MkGyPVY2Pzl:L3G+
PC3 NWGxdnVbSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MnS2N{Bl[Xm| MYrFSFUxKD1iMD6wNFg5PyEQvF2= NHr6Smo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUK5OlU4QSd-MkGyPVY2Pzl:L3G+
KB NFPRSYlEgXSxdH;4bYNqfHliYYPzZZk> M{PmcVczKGh? MY\HTVUxKD1iMD6wNFQ5PyEQvF2= NYf0VWRJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzNVY6PzdpPkKxN|E3QTd5PD;hQi=>
DU145 NVrDXItCS3m2b4TvfIlkcXS7IHHzd4F6 MYm3NkBp NU\qRWtlT0l3MDC9JFAvODB3NUWg{txO MoO0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|MU[5O|coRjJzM{G2PVc4RC:jPh?=
A549 MnW4R5l1d3SxeHnjbZR6KGG|c3H5 MnrRO|IhcA>? MUDHTVUxKD1iMD6wNFU2QCEQvF2= Mlq3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|MU[5O|coRjJzM{G2PVc4RC:jPh?=
MES-SA NYm0PWRCSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NW\FNlJqUUN3MDC9JFAvODB{OU[g{txO M3y0VlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{K0Olg3Lz5{MUOyOFY5PjxxYU6=
MES-SA NUnwVWZOSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M4[5UmlEPTBiPTCwMlAxOjl4IN88US=> NUDsNJJ4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkGzNlQ3QDdpPkKxN|I1Pjh5PD;hQi=>
SF295 NV7uRnBTSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NUXBdGZiUUN3MDC9JFAvODJ2NUWg{txO MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN{NE[4O{c,OjF|MkS2PFc9N2F-
MES-SA M2L1VmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1qzZmlEPTBiPTCwMlAxOjl4IN88US=> Mnv5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|MkS2PVIoRjJzM{K0OlkzRC:jPh?=
MCF7 Mn3lR5l1d3SxeHnjbZR6KGG|c3H5 NIr0[GI1QCCq MX\JR|UxKD1iMD6wNFYh|ryP M3fxeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{SxO|E5Lz5{MUO0NVcyQDxxYU6=
HT-29 NFPt[2JEgXSxdH;4bYNqfHliYYPzZZk> M2\NbFQ5KGh? M33hc2lEPTBiPTCwMlAxPyEQvF2= MnqyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|NEG3NVgoRjJzM{SxO|E5RC:jPh?=
K562 NEXEVpFEgXSxdH;4bYNqfHliYYPzZZk> M2HmS|Q5KGh? Mo\VTWM2OCB;IEGuNVYh|ryP NIrR[m89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO0Nlc{PSd-MkGzOFI4OzV:L3G+
MCF7 NHfNeGpEgXSxdH;4bYNqfHliYYPzZZk> MUi0PEBp MnfqTWM2OCB;IEKuNVEh|ryP M{X6d|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{SyO|M2Lz5{MUO0Nlc{PTxxYU6=
A549 NYTW[Yw4S3m2b4TvfIlkcXS7IHHzd4F6 MVy0PEBp NXXsXZZ4UUN3MDC9JFIvPDZizszN M1\5blxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{SyO|M2Lz5{MUO0Nlc{PTxxYU6=
SGC MWHDfZRwfG:6aXPpeJkh[XO|YYm= MW[0PEBp MV\JR|UxKD1iMz6zOEDPxE1? MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTN2MkezOUc,OjF|NEK3N|U9N2F-
HCT116 NEPz[o5EgXSxdH;4bYNqfHliYYPzZZk> NYfL[YFoPDhiaB?= NU\QOoNtUUN3MDC9JFQvOzdizszN NGLlemY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO0Nlc{PSd-MkGzOFI4OzV:L3G+
multidrug-resistant K562 M4Du[GN6fG:2b4jpZ4l1gSCjc4PhfS=> NFzFZ4I1QCCq NX3SemVFUUN3MDC9JFUvPjNizszN NGPkcoM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO0Nlc{PSd-MkGzOFI4OzV:L3G+
CCRF-CEM NWL0RoFyS3m2b4TvfIlkcXS7IHHzd4F6 MW[3NkBp NITGb4dKSzVyIE2gNE4xODNizszN NGr3fJE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO1OlU6Oid-MkGzOVY2QTJ:L3G+
taxol-resistant CCRF-CEM NIPHR|REgXSxdH;4bYNqfHliYYPzZZk> NF7NbW84OiCq NIHRfYFKSzVyIE2gNE41OyEQvF2= NHPFelY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUO1OlU6Oid-MkGzOVY2QTJ:L3G+
vinblastine-resistant CCRF-CEM Mn7DR5l1d3SxeHnjbZR6KGG|c3H5 NHOwN5I4OiCq NFm4ZmNKSzVyIE2gNU4zPyEQvF2= MkfOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|NU[1PVIoRjJzM{W2OVkzRC:jPh?=
KB M2Dj[mN6fG:2b4jpZ4l1gSCjc4PhfS=> MoPQN{Bl[Xm| MX\HTVUxKD1iMD6wNFUyPiEQvF2= M4X3R|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzM{e3N|Y5Lz5{MUO3O|M3QDxxYU6=
DU145 M3X0R2N6fG:2b4jpZ4l1gSCjc4PhfS=> MmjaN{Bl[Xm| MmP6S2k2OCB;IECuNFA2OjNizszN Mmr4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF|N{ezOlgoRjJzM{e3N|Y5RC:jPh?=
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CEM/VLB M1P0SmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NIPWbVM1QCCq MoXJTWM2OCB;IEOuN|Qh|ryP MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZyNEe0Okc,OjF4MES3OFY9N2F-
A549 NWrvfYlDSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MlfRO|IhcA>? MoLHTWM2OCB;IECuNFA4OiEQvF2= M3\xRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzNk[zN|E6Lz5{MU[2N|MyQTxxYU6=
taxol-resistant A549-T12 NWPXdXdRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Mn\mO|IhcA>? NFe2b3FKSzVyIE2gNE4xPzV{IN88US=> MlryQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF4NkOzNVkoRjJzNk[zN|E6RC:jPh?=
MCF7 MWTDfZRwfG:6aXPpeJkh[XO|YYm= MUC0PEBp NWTDboxxUUN3MDC9JFAvODB{NTFOwG0> MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTZ6MEG5NEc,OjF4OECxPVA9N2F-
MCF7/VP MlTpR5l1d3SxeHnjbZR6KGG|c3H5 MkPUOFghcA>? NWXORWZrUUN3MDC9JFAvODB{ODFOwG0> NFjTTHA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MU[4NFE6OCd-MkG2PFAyQTB:L3G+
NCI/ADR MoTSR5l1d3SxeHnjbZR6KGG|c3H5 MkDCOFghcA>? NVLVSmNlUUN3MDC9JFIvPyEQvF2= NWLuc4drRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG2PFAyQTBpPkKxOlgxOTlyPD;hQi=>
LT12 NEL2dpBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NGe1[JQ1QCCq M2roe2lEPTBiPTCwMlAxPiEQvF2= MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTdyNUKyN{c,OjF5MEWyNlM9N2F-
NCI-H460 Mo[2R5l1d3SxeHnjbZR6KGG|c3H5 M4HSO|Q5KGh? Mmq3TWM2OCB;IECuNFEh|ryP NYLjZ4FzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3NFUzOjNpPkKxO|A2OjJ|PD;hQi=>
SF268 NYP0c3YyS3m2b4TvfIlkcXS7IHHzd4F6 MUC0PEBp NEfSUlRKSzVyIE2gNE4xOSEQvF2= NI\rT5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUewOVIzOyd-MkG3NFUzOjN:L3G+
KB/HeLa M4XidGN6fG:2b4jpZ4l1gSCjc4PhfS=> MoHoOFghcA>? MWjJR|UxKD1iMD6wNUDPxE1? M1jQV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzN{C1NlI{Lz5{MUewOVIzOzxxYU6=
SKOV3 MmXSR5l1d3SxeHnjbZR6KGG|c3H5 Mnu2OFghcA>? M2n2R2lEPTBiPTCwMlAyKM7:TR?= NHjvZVc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUewOVIzOyd-MkG3NFUzOjN:L3G+
RKOp27 NULabY9pS3m2b4TvfIlkcXS7IHHzd4F6 NYXlRnltPDhiaB?= NHzw[mFKSzVyIE2gNE4xOSEQvF2= MlHZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF5MEWyNlMoRjJzN{C1NlI{RC:jPh?=
P388 NEfleplCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MoHsOFghcA>? NH\pbldKSzVyIE2gNE4xPCEQvF2= MXq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTdyNUKyN{c,OjF5MEWyNlM9N2F-
L1210 NUXRU21USW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NIHGWIo1QCCq NWHVToluUUN3MDC9JFAvODZizszN NHq0[489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUewOVIzOyd-MkG3NFUzOjN:L3G+
NCI-H460 NHy5e4hCdnSrY3HuZ4VzKGG|c3H5 MYO3NkBp M4DJbGlEOzBiPTCzMlYh|ryP MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTdyN{C0Okc,OjF5MEewOFY9N2F-
A2780 NVjQeHBVS3m2b4TvfIlkcXS7IHHzd4F6 MV:0PEBp Mn3WTWM2OCB;IECuNFAxPjJizszN NX7mSVk6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3OlQ{ODhpPkKxO|Y1OzB6PD;hQi=>
A2780AD NVKzepJNS3m2b4TvfIlkcXS7IHHzd4F6 NYXnS|Q{PDhiaB?= NIDodmtKSzVyIE2gNU46KM7:TR?= M3XsVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzN{[0N|A5Lz5{MUe2OFMxQDxxYU6=
786-0 MXjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NXz2ZmRbUUN3MDC9JFAvODB2IN88US=> NW[1W4VSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|Q1QTlpPkKxO|c1PDl7PD;hQi=>
PC3 NWfOV4t5SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NEj2TFJKSzVyIE2gNE4xODB2MzFOwG0> NFvqWZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe3OVE2OCd-MkG3O|UyPTB:L3G+
DU145 MY\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M1P1fWlEPTBiPTCwMlAxOjNizszN NVXLPHhZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|UyPTBpPkKxO|c2OTVyPD;hQi=>
MDA-MB-435 M2G4eGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NX\0[Iw1UUN3MDC9JFAvODF4IN88US=> NF3LRok9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe3OVE2OCd-MkG3O|UyPTB:L3G+
MCF7 NIHQd2tEgXSxdH;4bYNqfHliYYPzZZk> NHr1c4I1QCCq NGf0[nNKSzVyIE2gNE4xODF4MjFOwG0> NYrSW5ZZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3O|k2OTlpPkKxO|c6PTF7PD;hQi=>
COLO205 MXvDfZRwfG:6aXPpeJkh[XO|YYm= NIK2WJc1QCCq NYnOUnYxUUN3MDC9JFAvODB|M{Gg{txO M4fpbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzN{e5OVE6Lz5{MUe3PVUyQTxxYU6=
KB MljFR5l1d3SxeHnjbZR6KGG|c3H5 NWraNJVnUUN3MDC9JFYvPjh2IN88US=> NVvlSmVERGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG3PFQ3OzFpPkKxO|g1PjNzPD;hQi=>
DU145 M4HqNGN6fG:2b4jpZ4l1gSCjc4PhfS=> NFXqSY9KSzVyIE2gPE43OjZizszN NIK4fVM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe4OFY{OSd-MkG3PFQ3OzF:L3G+
A549 Ml;6R5l1d3SxeHnjbZR6KGG|c3H5 M4nkeWlEPTBiPTC5MlI3PSEQvF2= NGTjVI49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe4OFY{OSd-MkG3PFQ3OzF:L3G+
HeLa Mk\iRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYTJR|UxKD1iMD6wNFE{QCEQvF2= NIjQcIw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUe4Olc6Oyd-MkG3PFY4QTN:L3G+
SKOV3 NXPtN|VlSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NV3NR5drUUN3MDC9JFAvODB{OUWg{txO MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTd6Nke5N{c,OjF5OE[3PVM9N2F-
HeLa MYPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NYnpcFAxPDhiaB?= NYjsfFR{UUN3MDC9JFAvODBzMjFOwG0> NF\K[Vg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUiwNFg{QSd-MkG4NFA5Ozl:L3G+
A2780 NWDQPVVFS3m2b4TvfIlkcXS7IHHzd4F6 NYjsfmlyOiCmYYnz NFm5RVVKSzVyIE2gNE4xOTRizszN MmnvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6MEK5OVcoRjJzOECyPVU4RC:jPh?=
Hep3B2 MoHzR5l1d3SxeHnjbZR6KGG|c3H5 NEHBUIs4OiCq NWnBbmZ1UUN3MDC9JFAvODByMEG2JO69VQ>? NIC0WZg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUixNlQyOCd-MkG4NVI1OTB:L3G+
PANC1 MUXDfZRwfG:6aXPpeJkh[XO|YYm= Mnz0O|IhcA>? NXOyS2l{UUN3MDC9JFAvODBzMTFOwG0> M4jqSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFExLz5{MUixNlQyODxxYU6=
CNE1-LMP1 MWLDfZRwfG:6aXPpeJkh[XO|YYm= NELme404OiCq MlWzTWM2OCB;IECuNFA1OiEQvF2= Mn;5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6MUK0NVAoRjJzOEGyOFExRC:jPh?=
MGC MXzDfZRwfG:6aXPpeJkh[XO|YYm= M3P4blczKGh? NWrXfm5VUUN3MDC9JFAvODB4NDFOwG0> MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOThzMkSxNEc,OjF6MUK0NVA9N2F-
A375 MkGwR5l1d3SxeHnjbZR6KGG|c3H5 Mny0O|IhcA>? M1nwT2lEPTBiPTCwMlAxQDlizszN MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOThzMkSxNEc,OjF6MUK0NVA9N2F-
MCF7 MULDfZRwfG:6aXPpeJkh[XO|YYm= NV;6dmNuPzJiaB?= MWnJR|UxKD1iMD6wNVQh|ryP NVvOcZJPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4NVI1OTBpPkKxPFEzPDFyPD;hQi=>
HaCaT Ml7WR5l1d3SxeHnjbZR6KGG|c3H5 MoDyO|IhcA>? MW\JR|UxKD1iMD6wNlQh|ryP M1PCflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFExLz5{MUixNlQyODxxYU6=
A549 NYLqZmYzS3m2b4TvfIlkcXS7IHHzd4F6 MUe3NkBp NFvl[3pKSzVyIE2gNE4xOyEQvF2= MoT0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6MUK0NVAoRjJzOEGyOFExRC:jPh?=
EC109 MYHDfZRwfG:6aXPpeJkh[XO|YYm= M3XkbFczKGh? NWf0b41CUUN3MDC9JFAvOTRizszN MnLjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6MUK0NVAoRjJzOEGyOFExRC:jPh?=
MES-SA Ml;UR5l1d3SxeHnjbZR6KGG|c3H5 M1LtW|k3KGh? M2fUSmlEPTBiPTCwMlAxPCEQvF2= M{XnOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFIyLz5{MUixNlQzOTxxYU6=
MES-SA/Dx5 NE\0R4FEgXSxdH;4bYNqfHliYYPzZZk> MX65OkBp MoXmTWM2OCB;IECuO|Uh|ryP M3rsdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEGyOFIyLz5{MUixNlQzOTxxYU6=
HT-29 NV22XmEyS3m2b4TvfIlkcXS7IHHzd4F6 NXfUTlg2T0l3MDC9JFAvODB{IN88US=> NGHl[WM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
RPMI8226 NEDsUIZEgXSxdH;4bYNqfHliYYPzZZk> NX6zUmlIT0l3MDC9JFAvODB{IN88US=> NEfleog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
HCC2998 NYfjRYZqS3m2b4TvfIlkcXS7IHHzd4F6 NIrJPJBIUTVyIE2gNE4xODNizszN M{ThXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEO5OlQxLz5{MUizPVY1ODxxYU6=
Hs578T M3nWcGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVfHTVUxKD1iMD6wNFMh|ryP MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh|OU[0NEc,OjF6M{m2OFA9N2F-
COLO205 NVn0RnF7S3m2b4TvfIlkcXS7IHHzd4F6 M3HId2dKPTBiPTCwMlAxOyEQvF2= MnnNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6M{m2OFAoRjJzOEO5OlQxRC:jPh?=
PC3 NH\U[llEgXSxdH;4bYNqfHliYYPzZZk> MnPqS2k2OCB;IECuNFA1KM7:TR?= NHTk[mg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
A549 MUHDfZRwfG:6aXPpeJkh[XO|YYm= M4TOT2dKPTBiPTCwMlAxPCEQvF2= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh|OU[0NEc,OjF6M{m2OFA9N2F-
SNB75 MV;DfZRwfG:6aXPpeJkh[XO|YYm= MYXHTVUxKD1iMD6wNFQh|ryP M3v5SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEO5OlQxLz5{MUizPVY1ODxxYU6=
KM12 MoTrR5l1d3SxeHnjbZR6KGG|c3H5 M33sNWdKPTBiPTCwMlAxPCEQvF2= NHizUYw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
DU145 NHnEeHJEgXSxdH;4bYNqfHliYYPzZZk> MWjHTVUxKD1iMD6wNFUh|ryP M1TWRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEO5OlQxLz5{MUizPVY1ODxxYU6=
SKOV3 NV:5WmF5S3m2b4TvfIlkcXS7IHHzd4F6 MmXtS2k2OCB;IECuNFA5KM7:TR?= MkTNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6M{m2OFAoRjJzOEO5OlQxRC:jPh?=
NCI-H322M M1[4bGN6fG:2b4jpZ4l1gSCjc4PhfS=> M1rNRWdKPTBiPTCwMlAyOyEQvF2= NFXxUVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
UACC257 NULkZnlwS3m2b4TvfIlkcXS7IHHzd4F6 MnXrS2k2OCB;IECuNFQh|ryP NH[wPJI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUizPVY1OCd-MkG4N|k3PDB:L3G+
HCT15 NFvNXJBEgXSxdH;4bYNqfHliYYPzZZk> NWjSbGJFT0l3MDC9JFAvOTV6IN88US=> MmnRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6M{m2OFAoRjJzOEO5OlQxRC:jPh?=
ACHN MWTDfZRwfG:6aXPpeJkh[XO|YYm= MYLHTVUxKD1iMD6zPVgh|ryP MmXEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6M{m2OFAoRjJzOEO5OlQxRC:jPh?=
HL60 Mlf5R5l1d3SxeHnjbZR6KGG|c3H5 NUf4fmVyPzJiaB?= MVvJR|UxKD1iMD6wNFM1KM7:TR?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh2OEK2PEc,OjF6NEiyOlg9N2F-
MCF7 NVXlZm1tSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NF\tdlQ6PiCq NGfnOWVKSzVyIE2gNE4xODB7MTFOwG0> NF3DcHE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3NFc6PSd-MkG4O|A4QTV:L3G+
A549 NIn0VHZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M4XIfVczKGh? MkfmTWM2OCB;IECuNFA{OTRizszN NV\zNJJORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|A4QTVpPkKxPFcxPzl3PD;hQi=>
A549 M3v1dmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVLLd2hxOjRiaB?= NViyVFJqTUN3MDC9JFAvODB2NjFOwG0> NXjiO4xTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|MxPjhpPkKxPFc{ODZ6PD;hQi=>
KB MkThR5l1d3SxeHnjbZR6KGG|c3H5 MVvJR|UxKD1iMD6wPEDPxE1? NX7ncFUyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|U4PjRpPkKxPFc2PzZ2PD;hQi=>
786-0 NXTl[3JZS3m2b4TvfIlkcXS7IHHzd4F6 NHjlT49KSzVyIE2gNE4xQCEQvF2= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh5NUe2OEc,OjF6N{W3OlQ9N2F-
OS-RC2 NIDLO5ZEgXSxdH;4bYNqfHliYYPzZZk> NEfzSo5KSzVyIE2gNE4xQCEQvF2= NH\hS|U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3OVc3PCd-MkG4O|U4PjR:L3G+
22Rv1 M1i2c2N6fG:2b4jpZ4l1gSCjc4PhfS=> NGfydJlKSzVyIE2gNE4xQCEQvF2= NHjjXm49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3OVc3PCd-MkG4O|U4PjR:L3G+
HepG2 NIrZXHFEgXSxdH;4bYNqfHliYYPzZZk> MlXzTWM2OCB;IECuNFgh|ryP M175NFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEe1O|Y1Lz5{MUi3OVc3PDxxYU6=
HT-29 MoXyR5l1d3SxeHnjbZR6KGG|c3H5 Mn;TTWM2OCB;IECuN|gh|ryP NYOwbGhVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG4O|U4PjRpPkKxPFc2PzZ2PD;hQi=>
A375 NHq1WolEgXSxdH;4bYNqfHliYYPzZZk> NYrDSGJjUUN3MDC9JFAvQDFizszN NInXfGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi3OVc3PCd-MkG4O|U4PjR:L3G+
MCF7 M1PqUGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWTldHo6UUN3MDC9JFEvOyEQvF2= MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh5NUe2OEc,OjF6N{W3OlQ9N2F-
BGC823 NX;Zdlh1S3m2b4TvfIlkcXS7IHHzd4F6 NInxfFhKSzVyIE2gNU42KM7:TR?= Mnn6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6N{W3OlQoRjJzOEe1O|Y1RC:jPh?=
769-P Ml;rR5l1d3SxeHnjbZR6KGG|c3H5 NHH6PHhKSzVyIE2gO{4yKM7:TR?= MX:8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh5NUe2OEc,OjF6N{W3OlQ9N2F-
MCF7 MWjDfZRwfG:6aXPpeJkh[XO|YYm= NV;mWZpCOyCmYYnz MUXHTVUxKD1iMT6wO{DPxE1? MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTh6OUO0NUc,OjF6OEmzOFE9N2F-
PC3 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MVizJIRigXN? MX\HTVUxKD1iMT60OkDPxE1? NHfZXFM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUi4PVM1OSd-MkG4PFk{PDF:L3G+
SK-N-SH M1LvdGN6fG:2b4jpZ4l1gSCjc4PhfS=> NGLQXYo{KGSjeYO= M3zrXmdKPTBiPTCyMlE6KM7:TR?= M2\yVFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOEi5N|QyLz5{MUi4PVM1OTxxYU6=
HeLa M4K3fWN6fG:2b4jpZ4l1gSCjc4PhfS=> MVyzJIRigXN? NVXzR2lyT0l3MDC9JFIvQDJizszN MnjSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF6OEmzOFEoRjJzOEi5N|QyRC:jPh?=
CHO-VV 3-2 NHTSSHVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NFvZSnU1QCCq M{jHWmlEPTBiPTCwMlE1KM7:TR?= M1iwdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUKwOlM5Lz5{MUmyNFY{QDxxYU6=
CHO-TAX 5-6 NHrHUWRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MkKxOFghcA>? MmTxTWM2OCB;IECuOVIh|ryP M2LMdlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUKwOlM5Lz5{MUmyNFY{QDxxYU6=
multidrug-resistant CEM/VLB NYG5[HJRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NXe5cmlmPDhiaB?= M{TYNGlEPTBiPTCzMlM1KM7:TR?= NFvZUVA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmyNFY{QCd-MkG5NlA3Ozh:L3G+
BGC823 M37rSWN6fG:2b4jpZ4l1gSCjc4PhfS=> NIDZclNKSzVyIE2gNE4xODN{OTFOwG0> M1HiW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUK4O|k4Lz5{MUmyPFc6PzxxYU6=
HT-29 M37vdmN6fG:2b4jpZ4l1gSCjc4PhfS=> NX3u[I83UUN3MDC9JFAvODB|OUSg{txO NGjNcWE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmyPFc6Pyd-MkG5Nlg4QTd:L3G+
HepG2 MoX3R5l1d3SxeHnjbZR6KGG|c3H5 NV\j[GNtUUN3MDC9JFAvODB2NDFOwG0> MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl{OEe5O{c,OjF7Mki3PVc9N2F-
A375 NWr6ZVJpS3m2b4TvfIlkcXS7IHHzd4F6 NETlSpFKSzVyIE2gNE4xODR7IN88US=> NW\VZYFzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5Nlg4QTdpPkKxPVI5Pzl5PD;hQi=>
A549 NWeyOFZvS3m2b4TvfIlkcXS7IHHzd4F6 NGX0[Y1KSzVyIE2gNE4xPDR7IN88US=> NFrPfnA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MUmyPFc6Pyd-MkG5Nlg4QTd:L3G+
NCI-H460 MVTDfZRwfG:6aXPpeJkh[XO|YYm= Mk\zTWM2OCB;IEig{txO MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl2Mke2OUc,OjF7NEK3OlU9N2F-
A549 MXHDfZRwfG:6aXPpeJkh[XO|YYm= NF\5OHA1QCCq NXTWNZIzUUN3MDC9JFAvODFizszN MnzjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7N{OwOVQoRjJzOUezNFU1RC:jPh?=
HeLa NFjzV2FEgXSxdH;4bYNqfHliYYPzZZk> NXrQNGdUPDhiaB?= NHvyUnFKSzVyIE2gNE43KM7:TR?= NXnnRlhORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5O|MxPTRpPkKxPVc{ODV2PD;hQi=>
HT-29 M1fxNGN6fG:2b4jpZ4l1gSCjc4PhfS=> NWjyZVI6OyCmYYnz MX;FSFUxKD1iMD6wNFYh|ryP MXO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl5M{GwNUc,OjF7N{OxNFE9N2F-
HBL100 NHvDcndIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NH2xdpRIUTVyIE2gNE4xODByMUeg{txO NVfzeZhSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5PFY2QDVpPkKxPVg3PTh3PD;hQi=>
HeLa MnHQS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NYrWNmJNT0l3MDC9JFAvODByMEOzJO69VQ>? MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl6NkW4OUc,OjF7OE[1PFU9N2F-
T47D M2LoeGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NWXudoRRT0l3MDC9JFAvODByMUWg{txO MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl6NkW4OUc,OjF7OE[1PFU9N2F-
WiDr MWnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MWLHTVUxKD1iMD6wNFAzOiEQvF2= M{X6b|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJzOUi2OVg2Lz5{MUm4OlU5PTxxYU6=
A2780 NVHGbXRWT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYiy[lhCT0l3MDC9JFAvODByMkeg{txO MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOTl6NkW4OUc,OjF7OE[1PFU9N2F-
SW1573 MlnCS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M1XuOmdKPTBiPTCwMlAxPSEQvF2= MmjPQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjF7OE[1PFUoRjJzOUi2OVg2RC:jPh?=
A2780 NFXE[GlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{jRemlEPTBiPTCwMlAyPyEQvF2= NVPH[2g{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkG5PVU2PDJpPkKxPVk2PTR{PD;hQi=>
A549 NVe4NZhZSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NFny[mk4OiCq M4HvVGlEPTBiPTCwMlAxPzJizszN NEm2PFk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkCyO|ExOCd-MkKwNlcyODB:L3G+
taxol-resistant A549-T12 NVLPR3RwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NYPUVGxxPzJiaB?= MmXTTWM2OCB;IECuNFc2KM7:TR?= M{XLcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEK3NVAxLz5{MkCyO|ExODxxYU6=
OVCAR8 M4m1OGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NGLS[2s6PiCq NVf5OFlTUUN3MDC9JFAvODB{IN88US=> MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjB2NEG2OEc,OjJyNESxOlQ9N2F-
NCI-ADR-RES MoLjS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M2q2PVk3KGh? M{fQNGlEPTBiPTCxMlUh|ryP NWPa[nc3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwOFQyPjRpPkKyNFQ1OTZ2PD;hQi=>
KB MYDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkDaO|IhcA>? MWHJR|UxKD1iMD6wNFM{KM7:TR?= M2fOOVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{ME[wNFM{Lz5{MkC2NFA{OzxxYU6=
KB-7d M1Ptdmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWK3NkBp MlHkTWM2OCB;IECuNFA4QSEQvF2= NYq0c|JvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKwOlAxOzNpPkKyNFYxODN|PD;hQi=>
KB-S15 NH7zZ5ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWO3NkBp NFvjPVdKSzVyIE2gNE4zPzNizszN NGXidWk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC2NFA{Oyd-MkKwOlAxOzN:L3G+
A2780 M{j0T2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MojKNkBl[Xm| NEDIUIpKSzVyIE2gNE4xOTVizszN NEDnTos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC3NVUzPid-MkKwO|E2OjZ:L3G+
KB NUTLZ3RbS3m2b4TvfIlkcXS7IHHzd4F6 M4\ROVQ5KGh? NXrNPYZ2UUN3MDC9JFAvODB2NTFOwG0> NHjYTXc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkC3OFI2Pyd-MkKwO|QzPTd:L3G+
L1210 MWrDfZRwfG:6aXPpeJkh[XO|YYm= NYPLS3pDPDhiaB?= MVfJR|UxKD1iMD6xNkDPxE1? M2Hz[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MEe0NlU4Lz5{MkC3OFI2PzxxYU6=
A2780 NETlXZJCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NWftVnBPOiCmYYnz M4P3OmlEPTBiPTCwMlAzKM7:TR?= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF|NkWyN{c,OjJzM{[1NlM9N2F-
DU145 M4O0XWN6fG:2b4jpZ4l1gSCjc4PhfS=> NUXTSZlrTUN3MDC9JFAvODB3OTFOwG0> MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF2MkW0N{c,OjJzNEK1OFM9N2F-
KB M3zPcWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmDRSWM2OCB;IECuNFA3KM7:TR?= MnzOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzNEK1OFMoRjJ{MUSyOVQ{RC:jPh?=
A549 M{TtXGN6fG:2b4jpZ4l1gSCjc4PhfS=> MkXCSWM2OCB;IECuNFA3PCEQvF2= NX65b2RMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxOFI2PDNpPkKyNVQzPTR|PD;hQi=>
QGY7701 NWjpSnF{S3m2b4TvfIlkcXS7IHHzd4F6 MXW3NkBp MVvJR|UxKD1iMD6wOEDPxE1? NVfXS4ZJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxOVM{OzhpPkKyNVU{OzN6PD;hQi=>
HepG2 NXf5cIM{S3m2b4TvfIlkcXS7IHHzd4F6 NVrNbJlLPzJiaB?= MkjtTWM2OCB;IECuNFUh|ryP MUe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjF3M{OzPEc,OjJzNUOzN|g9N2F-
Bel7404 M2nVc2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mo\1O|IhcA>? M13BXWlEPTBiPTCwMlgzKM7:TR?= MmruQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJzNUOzN|goRjJ{MUWzN|M5RC:jPh?=
SMMC7721 NIrB[HFEgXSxdH;4bYNqfHliYYPzZZk> NXq3TYpNPzJiaB?= M2\Qb2lEPTBiPTCwMlg5KM7:TR?= NWq0fHlDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxOVM{OzhpPkKyNVU{OzN6PD;hQi=>
Bel7402 MkXZR5l1d3SxeHnjbZR6KGG|c3H5 NXXDUYFmPzJiaB?= M1HDTWlEPTBiPTCxMlI2KM7:TR?= NUGyVGpmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKxOVM{OzhpPkKyNVU{OzN6PD;hQi=>
MCF7 NH3hWHREgXSxdH;4bYNqfHliYYPzZZk> MVOyOEB1dyB2ODDo NEPNfYdKSzVyIE2gNE4xODNizszN NEPvbIs9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKyNlA1OCd-MkKyNlIxPDB:L3G+
SH-SY5Y Ml\zR5l1d3SxeHnjbZR6KGG|c3H5 MXyyOEB1dyB2ODDo NXW0dG46UUN3MDC9JFAvODB2IN88US=> NIS5WVY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkKyNlA1OCd-MkKyNlIxPDB:L3G+
HepG2 M2m1VWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXflZ|FNOjRidH:gOFghcA>? NEf6ZpdKSzVyIE2gNE4xODdizszN NXfNSYdVRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKyNlIxPDBpPkKyNlIzODRyPD;hQi=>
H460 NIPv[lFEgXSxdH;4bYNqfHliYYPzZZk> Ml33NlQhfG9iNEigbC=> M1rE[2lEPTBiPTCwMlAxQCEQvF2= M3\1TlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkKyNFQxLz5{MkKyNlA1ODxxYU6=
HT-29 NWX2SJNrS3m2b4TvfIlkcXS7IHHzd4F6 NYP3O5lzOyCmYYnz M1m1e2lEPTBiPTCwMlAxPiEQvF2= M2HO[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{MkO5OlAyLz5{MkKzPVYxOTxxYU6=
DU145 MVrBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NHewT4Q4OiCq NVy4dnZ4T0l3MDC9JFAvODB|OE[g{txO M3mzTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{Mk[1Olg2Lz5{MkK2OVY5PTxxYU6=
KB NVG4ZVF4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NXrKdG82PzJiaB?= Ml\TS2k2OCB;IECuNFA1OTJizszN MkLUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ{NkW2PFUoRjJ{Mk[1Olg2RC:jPh?=
A549 NWLG[HJSSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MW[3NkBp MojiS2k2OCB;IECuNFA2PDZizszN MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjJ4NU[4OUc,OjJ{NkW2PFU9N2F-
MCF7 MX7DfZRwfG:6aXPpeJkh[XO|YYm= MVu5OkBp MnTtTWM2OCB;IECuNUDPxE1? NXPGSZVqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkKzOlA3OTNpPkKyN|YxPjF|PD;hQi=>
A549 MoTvR5l1d3SxeHnjbZR6KGG|c3H5 M{mwd|czKGh? NYjST2RPUUN3MDC9JFAvOTlizszN NF3NNGU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkS3NlA1Oyd-MkK0O|IxPDN:L3G+
MCF7 M4K3SmN6fG:2b4jpZ4l1gSCjc4PhfS=> MlzKOFghcA>? MVHJR|UxKD1iMD6wNFYh|ryP M1vuVlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEeyNFQ2Lz5{MkS3NlA1PTxxYU6=
K562 NVHmN5J[S3m2b4TvfIlkcXS7IHHzd4F6 MX63NkBp MmrYTWM2OCB;IECuOFEh|ryP MmH2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ2OEOwPVAoRjJ{NEizNFkxRC:jPh?=
CaEs17 M{THW2N6fG:2b4jpZ4l1gSCjc4PhfS=> NXjTd3FsPzJiaB?= NV;zUJN4UUN3MDC9JFAvPDNizszN MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR6M{C5NEc,OjJ2OEOwPVA9N2F-
MGC803 M13FXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MoO5O|IhcA>? NH;tWndKSzVyIE2gNE45PSEQvF2= MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR6M{C5NEc,OjJ2OEOwPVA9N2F-
HeLa NUG3flQ{S3m2b4TvfIlkcXS7IHHzd4F6 MlrkO|IhcA>? M4e5T2lEPTBiPTCwMlg6KM7:TR?= NXfGfHFwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0PFMxQTBpPkKyOFg{ODlyPD;hQi=>
Bel7402 MYjDfZRwfG:6aXPpeJkh[XO|YYm= MlKwO|IhcA>? NFezRnJKSzVyIE2gNU45QSEQvF2= NWrsXmtCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK0PFMxQTBpPkKyOFg{ODlyPD;hQi=>
A549 NHH2NZhEgXSxdH;4bYNqfHliYYPzZZk> M3uyUVczKGh? M32wUWlEPTBiPTCzMlQ3KM7:TR?= MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjR6M{C5NEc,OjJ2OEOwPVA9N2F-
MCF7 Mn;RR5l1d3SxeHnjbZR6KGG|c3H5 MVy3NkBp NYTWR|luUUN3MDC9JFQvPzdizszN M4D1XFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NEizNFkxLz5{MkS4N|A6ODxxYU6=
SKOV3 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NXzyc5J5UUN3MDC9JFAvODByMTFOwG0> M{LyUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUC2OlIxLz5{MkWwOlYzODxxYU6=
BGC823 NHr6TGhEgXSxdH;4bYNqfHliYYPzZZk> NYLhRmRWUUN3MDC9JFAvODB|MzFOwG0> Mo\1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3ME[2NlAoRjJ{NUC2OlIxRC:jPh?=
HepG2 M1\uTGN6fG:2b4jpZ4l1gSCjc4PhfS=> NIDEW4pKSzVyIE2gNE4xODR2IN88US=> MoPCQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3ME[2NlAoRjJ{NUC2OlIxRC:jPh?=
A549 MV;DfZRwfG:6aXPpeJkh[XO|YYm= MYjJR|UxKD1iMD6wNVYh|ryP NFfwc5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwOlYzOCd-MkK1NFY3OjB:L3G+
HCT8 NGjmSlFEgXSxdH;4bYNqfHliYYPzZZk> NWjPPVdHUUN3MDC9JFAvODVzIN88US=> NHjUXZM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwOlYzOCd-MkK1NFY3OjB:L3G+
CCRF-CEM M36zXWN6fG:2b4jpZ4l1gSCjc4PhfS=> NXPSd4l5PzJiaB?= NEfKbI5KSzVyIE2gNE4xODF{IN88US=> NEmzUY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkWwO|g6Oyd-MkK1NFc5QTN:L3G+
taxol-resistant CCRF-CEM MoS4R5l1d3SxeHnjbZR6KGG|c3H5 MY[3NkBp Mn\UTWM2OCB;IECuOFMh|ryP MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjVyN{i5N{c,OjJ3MEe4PVM9N2F-
vinblastine-resistant CCRF-CEM NXm2Tol[S3m2b4TvfIlkcXS7IHHzd4F6 M4PQc|czKGh? Mm\yTWM2OCB;IEGuNlch|ryP M2PFeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NUC3PFk{Lz5{MkWwO|g6OzxxYU6=
BGC823 NF;RU41EgXSxdH;4bYNqfHliYYPzZZk> MX63NkBp NFjnN25KSzVyIE2gNE4xODFizszN Ml25QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ3OEOwO|koRjJ{NUizNFc6RC:jPh?=
A2780 MYrDfZRwfG:6aXPpeJkh[XO|YYm= MVO3NkBp M2fy[GlEPTBiPTCwMlAxOSEQvF2= MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV6M{C3PUc,OjJ3OEOwO|k9N2F-
Bel7402 MW\DfZRwfG:6aXPpeJkh[XO|YYm= NXrSWYVyPzJiaB?= MlO5TWM2OCB;IECuNFA3KM7:TR?= NVLDd|g6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1PFMxPzlpPkKyOVg{ODd7PD;hQi=>
A549 MULDfZRwfG:6aXPpeJkh[XO|YYm= MlLRO|IhcA>? MWHJR|UxKD1iMD6wNVYh|ryP NXvwVFdsRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK1PFMxPzlpPkKyOVg{ODd7PD;hQi=>
HCT8 NH\TbVhEgXSxdH;4bYNqfHliYYPzZZk> M{X0b|czKGh? M{XONWlEPTBiPTCwMlA2OSEQvF2= MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV6M{C3PUc,OjJ3OEOwO|k9N2F-
MES-SA M2jZNmN6fG:2b4jpZ4l1gSCjc4PhfS=> NF\UXGw6PiCq Mm\3TWM2OCB;IECuNFA1KM7:TR?= MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV6N{WxPUc,OjJ3OEe1NVk9N2F-
MESSA/DX5 MmmxR5l1d3SxeHnjbZR6KGG|c3H5 MX:5OkBp MUDJR|UxKD1iMD63OUDPxE1? MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjV6N{WxPUc,OjJ3OEe1NVk9N2F-
HCT116 NE\IOmhEgXSxdH;4bYNqfHliYYPzZZk> M4L2Z2lEPTBiPTCwMlA2KM7:TR?= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjZ7MUG3PUc,OjJ4OUGxO|k9N2F-
SKBR3 MWfDfZRwfG:6aXPpeJkh[XO|YYm= MYnJR|UxKD1iMD6xNUDPxE1? MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjZ7MUG3PUc,OjJ4OUGxO|k9N2F-
SK-MEL-5 M4PKUWN6fG:2b4jpZ4l1gSCjc4PhfS=> MX3JR|UxKD1iMD6xOUDPxE1? M2rRPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{NkmxNVc6Lz5{Mk[5NVE4QTxxYU6=
SKOV3 NWf6Ro5XS3m2b4TvfIlkcXS7IHHzd4F6 NInZ[3hKSzVyIE2gNE41KM7:TR?= NVXvSZBCRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK2PVEyPzlpPkKyOlkyOTd7PD;hQi=>
MCF7 NXvyXIwyS3m2b4TvfIlkcXS7IHHzd4F6 MYfJR|UxKD1iMD65JO69VQ>? NV;Fb5YyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK2PVEyPzlpPkKyOlkyOTd7PD;hQi=>
PC3 NU\se49zSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MXK0PEBp M2H6WGlEPTBiPTCwMlAxODRizszN M{XSUlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{N{izPVU1Lz5{Mke4N|k2PDxxYU6=
paclitaxel-resistant PC3-TxR Ml\wRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MUS0PEBp M3PqUWlEPTBiPTCwMlE5QCEQvF2= MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjd6M{m1OEc,OjJ5OEO5OVQ9N2F-
MCF7 NVL6dmI1S3m2b4TvfIlkcXS7IHHzd4F6 MnPLNlQhcA>? M1XYbGlEPTBiPTCwMlAyPSEQvF2= NUjvdo5pRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4NVgxQDFpPkKyPFE5ODhzPD;hQi=>
SKBR3 NY\aTo4zT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M3nlT|Q5KGh? MUnJR|UxKD1iMD6wNFE6KM7:TR?= NWjNdpJIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4OVAzOTRpPkKyPFUxOjF2PD;hQi=>
HepG2 NIXhTmhEgXSxdH;4bYNqfHliYYPzZZk> NHTBfGE4OiCq NIXIUo5KSzVyIE2gNE4xODB2NDFOwG0> MoDEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
MCF7 M4TndGN6fG:2b4jpZ4l1gSCjc4PhfS=> MYS3NkBp M{HKbmlEPTBiPTCwMlAxOyEQvF2= NV;LWpJiRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4O|EzOTdpPkKyPFcyOjF5PD;hQi=>
A375 M4fKTWN6fG:2b4jpZ4l1gSCjc4PhfS=> MnL3O|IhcA>? NVzqXHk2UUN3MDC9JFAvODB7MjFOwG0> MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh5MUKxO{c,OjJ6N{GyNVc9N2F-
BxPC3 M4\ZPWN6fG:2b4jpZ4l1gSCjc4PhfS=> MUG3NkBp NVHYO416UUN3MDC9JFAvODlizszN NFXhe2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Mki3NVIyPyd-MkK4O|EzOTd:L3G+
SMMC7721 NUK4[HZkS3m2b4TvfIlkcXS7IHHzd4F6 NV;PTXpsPzJiaB?= NWfjc40xUUN3MDC9JFAvOTVizszN MnrlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
PANC1 M2fiXmN6fG:2b4jpZ4l1gSCjc4PhfS=> M1PGO|czKGh? M37Xc2lEPTBiPTCwMlI3KM7:TR?= Mn3sQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
A549 NFvxc2REgXSxdH;4bYNqfHliYYPzZZk> NEDhc5E4OiCq NXTkR2hrUUN3MDC9JFAvPzJizszN MnfoQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
AGS M2HkNGN6fG:2b4jpZ4l1gSCjc4PhfS=> NV;pWXVrPzJiaB?= Mm\STWM2OCB;IEGuOkDPxE1? MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjh5MUKxO{c,OjJ6N{GyNVc9N2F-
NCI-H2126 M3T2fGN6fG:2b4jpZ4l1gSCjc4PhfS=> NF7STGg4OiCq M1vydmlEPTBiPTCyMlUh|ryP NVPTR2JzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK4O|EzOTdpPkKyPFcyOjF5PD;hQi=>
MDA-MB-231 M3;5SGN6fG:2b4jpZ4l1gSCjc4PhfS=> M3S2SFczKGh? M4\sTmlEPTBiPTC1JO69VQ>? MlLMQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
U87 MYDDfZRwfG:6aXPpeJkh[XO|YYm= M3LacFczKGh? NG\xXW9KSzVyIE2gPE4yKM7:TR?= MnTjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ6N{GyNVcoRjJ{OEexNlE4RC:jPh?=
HELF MWTDfZRwfG:6aXPpeJkh[XO|YYm= NUXqZnVbOjRiaB?= NEfZSW5KSzVyIE2gO{4yPCEQvF2= NVrmWXo2RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5NFE1OTBpPkKyPVAyPDFyPD;hQi=>
BGC MlW0R5l1d3SxeHnjbZR6KGG|c3H5 MnG1NlQhcA>? NI\tVYFKSzVyIE2gPU4zPiEQvF2= M1PvbFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ{OUCxOFExLz5{MkmwNVQyODxxYU6=
HELF NXrIOmlyS3m2b4TvfIlkcXS7IHHzd4F6 MUiyOEBp M4W1OmlEPTBiPTC3MlE1KM7:TR?= NF3wdpk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmyNVk3Pid-MkK5NlE6PjZ:L3G+
BGC M2f1[WN6fG:2b4jpZ4l1gSCjc4PhfS=> M3LKc|I1KGh? MlniTWM2OCB;IEmuNlYh|ryP MnzyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7MkG5OlYoRjJ{OUKxPVY3RC:jPh?=
DU145 M1L5W2N6fG:2b4jpZ4l1gSCjc4PhfS=> NF3KSYc4OiCq NYOzR21PT0l3MDC9JFAvODB{NUWg{txO NH;nOFU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{MkmzNlMyOyd-MkK5N|I{OTN:L3G+
KB NX;mS5duS3m2b4TvfIlkcXS7IHHzd4F6 MWC3NkBp MoLvS2k2OCB;IECuNFAzPjVizszN Mly5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7M{KzNVMoRjJ{OUOyN|E{RC:jPh?=
A549 M3LjVWN6fG:2b4jpZ4l1gSCjc4PhfS=> MmjlO|IhcA>? M4[wNmdKPTBiPTCwMlAxPDh7IN88US=> Mk\JQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjJ7M{KzNVMoRjJ{OUOyN|E{RC:jPh?=
KBVIN MYDDfZRwfG:6aXPpeJkh[XO|YYm= MkXIO|IhcA>? NVjiNXZVT0l3MDC9JFAvQTR6IN88US=> NYqzcmFWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5N|I{OTNpPkKyPVMzOzF|PD;hQi=>
HL60 MmnaR5l1d3SxeHnjbZR6KGG|c3H5 NF7qVoI4OiCq MnvTTWM2OCB;IECuNFAzQDJizszN NWDSSG1JRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5OVk2OThpPkKyPVU6PTF6PD;hQi=>
HeLa MmT6R5l1d3SxeHnjbZR6KGG|c3H5 NFW1dVY4OiCq MnfCTWM2OCB;IECuNFAzQTNizszN NX3xVpllRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkK5OVk2OThpPkKyPVU6PTF6PD;hQi=>
U937 NUPue|dbS3m2b4TvfIlkcXS7IHHzd4F6 Mkf6O|IhcA>? MmrCTWM2OCB;IECuNFA{OzdizszN MYm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOjl3OUWxPEc,OjJ7NUm1NVg9N2F-
HeLa NITIT3REgXSxdH;4bYNqfHliYYPzZZk> NIPa[3RKSzVyIE2gNUDPxE1? MkHHQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzMEOwPVcoRjJ|MUCzNFk4RC:jPh?=
A2780 MVjDfZRwfG:6aXPpeJkh[XO|YYm= NYTiVYNkUUN3MDC9JFEvOSEQvF2= MnX5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzMEOwPVcoRjJ|MUCzNFk4RC:jPh?=
A549 NFjlTmpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MWG3NkBp M4nIPWlEPTBiPTCwMlAxPzJizszN M1\IN|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MUG3NVcyLz5{M{GxO|E4OTxxYU6=
taxol-resistant A549-T12 M2\kPGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWC3NkBp MXPJR|UxKD1iMD6wO|UzKM7:TR?= NFHQ[I09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{GxO|E4OSd-MkOxNVcyPzF:L3G+
IGROV1/Pt1 NXnMTpVqS3m2b4TvfIlkcXS7IHHzd4F6 NEDJV5U4OiCq MULJR|UxKD1iMD6wNFIzKM7:TR?= NF7ZfIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G0NFM2QCd-MkOxOFA{PTh:L3G+
SKOV3 MXTDfZRwfG:6aXPpeJkh[XO|YYm= MXO3NkBp MoO5TWM2OCB;IECuNFAzPyEQvF2= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF2MEO1PEc,OjNzNECzOVg9N2F-
U2OS NInU[IVEgXSxdH;4bYNqfHliYYPzZZk> NGXKTnY4OiCq NGn2WmlKSzVyIE2gNE4xODN2IN88US=> MYi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF2MEO1PEc,OjNzNECzOVg9N2F-
PANC1 MnO3R5l1d3SxeHnjbZR6KGG|c3H5 NGTt[o44OiCq MWfJR|UxKD1iMD6wNFUzKM7:TR?= NXHjT401RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOFA{PThpPkKzNVQxOzV6PD;hQi=>
MIAPaCa2 M3TL[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NF64OWs4OiCq M1P4TWlEPTBiPTCwMlAxPzJizszN MVG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF2MEO1PEc,OjNzNECzOVg9N2F-
IGROV1 MVXDfZRwfG:6aXPpeJkh[XO|YYm= M2r6cVczKGh? M4\BV2lEPTBiPTCwMlAzOyEQvF2= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF2MEO1PEc,OjNzNECzOVg9N2F-
MES-SA MnLiR5l1d3SxeHnjbZR6KGG|c3H5 MkDOTWM2OCB;IECuNFA{KM7:TR?= MmTpQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNEG5NVYoRjJ|MUSxPVE3RC:jPh?=
A2780 MYXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NWTkTG13OiCmYYnz NHP6SndKSzVyIE2gNE4xOjhizszN MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF2OUOwOEc,OjNzNEmzNFQ9N2F-
MDA-MB-231 MnfLR5l1d3SxeHnjbZR6KGG|c3H5 NYTkVJFiPzJiaB?= Ml7FTWM2OCB;IECuNFUzKM7:TR?= M2X3[VxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MUWzN|k4Lz5{M{G1N|M6PzxxYU6=
HepG2 MULDfZRwfG:6aXPpeJkh[XO|YYm= NG\Ke2E4OiCq M2nPNWlEPTBiPTCwMlA2PCEQvF2= NUDabXZWRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOxOVM{QTdpPkKzNVU{Ozl5PD;hQi=>
A549 MlizR5l1d3SxeHnjbZR6KGG|c3H5 MlG4O|IhcA>? NGDuN4ZKSzVyIE2gNE4xPTZizszN MnfLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNUOzPVcoRjJ|MUWzN|k4RC:jPh?=
NUGC3 M4ThTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWnHTVUxKD1iMD6wNkDPxE1? M2rqS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MU[3OlE1Lz5{M{G2O|YyPDxxYU6=
HONE1 MVfHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M33wemdKPTBiPTCwMlAzKM7:TR?= NFLiWmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G2O|YyPCd-MkOxOlc3OTR:L3G+
NCI-H460 NWnFfGx6T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NV\WUY1QT0l3MDC9JFAvODNizszN NF3vVYI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G2O|YyPCd-MkOxOlc3OTR:L3G+
MCF7 MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MorXS2k2OCB;IECuNFMh|ryP NFL5V2w9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G2O|YyPCd-MkOxOlc3OTR:L3G+
A549 NXn1RZJ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MVnHTVUxKD1iMD6wOkDPxE1? MmHYQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzNke2NVQoRjJ|MU[3OlE1RC:jPh?=
HepG2 NWSyWnNkT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MWrHTVUxKD1iMD6xPEDPxE1? MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzF4N{[xOEc,OjNzNke2NVQ9N2F-
HeLa NEfhSFFEgXSxdH;4bYNqfHliYYPzZZk> NE\Ub5E6PiCq NFXtfFNKSzVyIE2gNE4xODFizszN NGPOU3k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{G3OlYzQCd-MkOxO|Y3Ojh:L3G+
SW780 M3HjemN6fG:2b4jpZ4l1gSCjc4PhfS=> M1\xUlk3KGh? Mli2TWM2OCB;IECuNFAyOSEQvF2= MkfhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjNzN{[2NlgoRjJ|MUe2OlI5RC:jPh?=
MESSA MXjDfZRwfG:6aXPpeJkh[XO|YYm= MmjhO|IhcA>? MXLJR|UxKD1iMD6wNFQh|ryP M2\0SVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG0OFUzLz5{M{KxOFQ2OjxxYU6=
OVCAR8 NV7qSFdoS3m2b4TvfIlkcXS7IHHzd4F6 M4fMWmlEPTBiPTCwMlAxPSEQvF2= M1rx[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG0OFUzLz5{M{KxOFQ2OjxxYU6=
HeLa NIL3W5pEgXSxdH;4bYNqfHliYYPzZZk> NXe3dFJXPDhiaB?= MoHOTWM2OCB;IECuNFA2KM7:TR?= NYrSN4JwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyNVQ1PTJpPkKzNlE1PDV{PD;hQi=>
A549 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NXHMeGppPDhiaB?= NXnCN5AyUUN3MDC9JFAvODB5IN88US=> M4DOfVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|MkG0OFUzLz5{M{KxOFQ2OjxxYU6=
HT-29 M{PFS2N6fG:2b4jpZ4l1gSCjc4PhfS=> M2T1fFQ5KGh? Mn\OTWM2OCB;IECuNFA5KM7:TR?= MnLlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{MUS0OVIoRjJ|MkG0OFUzRC:jPh?=
HCT15 MVzDfZRwfG:6aXPpeJkh[XO|YYm= M3;ue|czKGh? NULjfHFrUUN3MDC9JFAvODlizszN NH2yd|E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{KxOFQ2Oid-MkOyNVQ1PTJ:L3G+
MESSA/DX5 NVzsTmFZS3m2b4TvfIlkcXS7IHHzd4F6 NFj4bFI4OiCq NVnFNZU3UUN3MDC9JFEvPzZ2IN88US=> NE\1WoI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{KxOFQ2Oid-MkOyNVQ1PTJ:L3G+
NCI/ADR-RES NXn5dXBTS3m2b4TvfIlkcXS7IHHzd4F6 NVywWphxUUN3MDC9JFMvOyEQvF2= NUDPOXlHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyNVQ1PTJpPkKzNlE1PDV{PD;hQi=>
DU145 NFK1VFVIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NV;adWZXT0l3MDC9JFAvODB4NTFOwG0> MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJ5NEGyN{c,OjN{N{SxNlM9N2F-
KB MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NY\rXHF4T0l3MDC9JFAvODB5N{eg{txO NYDFZWJ4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyO|QyOjNpPkKzNlc1OTJ|PD;hQi=>
A549 M4fXT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3r2eGdKPTBiPTCwMlAxQDF6IN88US=> NUTENlUzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyO|QyOjNpPkKzNlc1OTJ|PD;hQi=>
KBVIN M2jB[Wdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MUnHTVUxKD1iMT64NFMh|ryP MmL6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN{N{SxNlMoRjJ|Mke0NVI{RC:jPh?=
K562 NVPIPVdHSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MWPJR|UxKD1iMD60NUDPxE1? NYXWOG5JRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkOyO|Q2PzBpPkKzNlc1PTdyPD;hQi=>
CaEs17 NFSzO5RCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NEGzWVZKSzVyIE2gNE41OyEQvF2= M3zwWFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|Mke0OVcxLz5{M{K3OFU4ODxxYU6=
MGC803 NGXMSIhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NUf2NZFGUUN3MDC9JFAvQDVizszN MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzJ5NEW3NEc,OjN{N{S1O|A9N2F-
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BGC823 NXW3V5dCS3m2b4TvfIlkcXS7IHHzd4F6 MnjvTWM2OCB;IECuNFA{PSEQvF2= NWTpdJF3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4NFYyOTJpPkKzPFA3OTF{PD;hQi=>
A549 NWPTWHpjS3m2b4TvfIlkcXS7IHHzd4F6 NF3VRWFKSzVyIE2gNE4xODN4IN88US=> NFLMblM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{iwOlEyOid-MkO4NFYyOTJ:L3G+
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MCF7 NYPOXVAyS3m2b4TvfIlkcXS7IHHzd4F6 MYC0PEBp NHW0Z2JKSzVyIE2gNE4xODhizszN NF32V|c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{ixPVg4OSd-MkO4NVk5PzF:L3G+
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HL60 NECyRXlEgXSxdH;4bYNqfHliYYPzZZk> NG\jVYk1QCCq NXS1OG1KUUN3MDC9JFAvODB6IN88US=> NXn3WmNJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4NVk5PzFpPkKzPFE6QDdzPD;hQi=>
SW480 NGnCZXREgXSxdH;4bYNqfHliYYPzZZk> MlLCOFghcA>? MnjsTWM2OCB;IECuNFQh|ryP MnLSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjN6MUm4O|EoRjJ|OEG5PFcyRC:jPh?=
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MCF7 NEjsPYZEgXSxdH;4bYNqfHliYYPzZZk> NXTjU3NOPzJiaB?= MVTHTVUxKD1iMD6wNFMh|ryP NYTQfVRNRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4N|E5OTFpPkKzPFMyQDFzPD;hQi=>
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MDA-MB-231 NH\nbZpEgXSxdH;4bYNqfHliYYPzZZk> MXq3NkBp M3XYR2lEPTBiPTCxJO69VQ>? M{\VWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OES4NVY{Lz5{M{i0PFE3OzxxYU6=
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rat lymphatic endothelial MlfrRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MoPROFghcA>? MVXJR|UxKD1iMD6wNVgh|ryP MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh3NUOzPEc,OjN6NUWzN|g9N2F-
HeLa NVTRfppwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NIrUV4w1QCCq MmryTWM2OCB;IECuNFAyOiEQvF2= NWjVPGhqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkO4OVU6PTNpPkKzPFU2QTV|PD;hQi=>
DU145 M{TES2N6fG:2b4jpZ4l1gSCjc4PhfS=> M4izUGdKPTBiPTCwMlAxPiEQvF2= NHvwV3A9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{M{i2O|YxPCd-MkO4Olc3ODR:L3G+
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HT-29 MlPoR5l1d3SxeHnjbZR6KGG|c3H5 MXq3NkBp NWPGWppPUUN3MDC9JFAvODByNjFOwG0> MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh7NUCxPUc,OjN6OUWwNVk9N2F-
HeLa NV32VJJNSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NIDpfFk1QCCq NHfXVWZKSzVyIE2gNE4xODF4IN88US=> M3zGSVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ|OEm1OVMzLz5{M{i5OVU{OjxxYU6=
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SKOV3/M6-6 isogenic NIrP[mNHfW6ldHnvckBie3OjeR?= NXfFcnp3PDhiaB?= MoPwTWM2OCB;IEKuOkDPxE1? MVy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zOzh7NUWzNkc,OjN6OUW1N|I9N2F-
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African green monkey Vero M{OwTGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NELJSIg1QCCq MkPhS2k2OCB;IECuNFMh|ryP NE\Kfmw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEeyO|Q3PCd-MkS3Nlc1PjR:L3G+
NCI-ADR-RES NGHj[JBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3vqTVQ5KGh? NVvWfmpmT0l3MDC9JFAvODRizszN NGfwTo89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEeyO|Q3PCd-MkS3Nlc1PjR:L3G+
NCI-H460 MWPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUG0PEBp MULHTVUxKD1iMD6xJO69VQ>? NFjDOmc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEeyO|Q3PCd-MkS3Nlc1PjR:L3G+
PC3 MlnJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NHvtU2E1QCCq M{WyVWdKPTBiPTCwMlEh|ryP MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd{N{S2OEc,OjR5Mke0OlQ9N2F-
K562 NIrrSnJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MXq0PEBp MX7HTVUxKD1iMD6xJO69VQ>? MmDWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR5Mke0OlQoRjJ2N{K3OFY1RC:jPh?=
OVCAR3 MlnFS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF6yblM1QCCq MkGyS2k2OCB;IECuNkDPxE1? MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDd{N{S2OEc,OjR5Mke0OlQ9N2F-
HepG2 MV;DfZRwfG:6aXPpeJkh[XO|YYm= MV2zJIRigXN? NIPlVW1KSzVyIE2gNE4xODBzOTFOwG0> NX3qcJNORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS3OFU6PjhpPkK0O|Q2QTZ6PD;hQi=>
KB MmfGR5l1d3SxeHnjbZR6KGG|c3H5 MmnqN{Bl[Xm| MX7JR|UxKD1iMD6wNFM6KM7:TR?= M4W3ZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2N{S1PVY5Lz5{NEe0OVk3QDxxYU6=
NCI-ADR-RES NUXoWHI4S3m2b4TvfIlkcXS7IHHzd4F6 NIXQdVRGSzVyIE2gNE4xOTNizszN MlLDQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6MEG2NVAoRjJ2OECxOlExRC:jPh?=
OVCAR8 MlXhR5l1d3SxeHnjbZR6KGG|c3H5 NYntb21YTUN3MDC9JFAvODF6IN88US=> NF[xTnI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEiwNVYyOCd-MkS4NFE3OTB:L3G+
NALM6 NGPHfINCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M2rKdFQ5KHSxIEeyJIg> NEnpWoNKSzVyIE2gNE4xODRzIN88US=> Mo\lQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6NUKyPFEoRjJ2OEWyNlgyRC:jPh?=
Jurkat NGLzO3RCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NWLrWGRsPDhidH:gO|IhcA>? NYrhbXRvUUN3MDC9JFAvODB2NTFOwG0> NICxbGI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEi1NlI5OSd-MkS4OVIzQDF:L3G+
K562 MULBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MUG0PEB1dyB5MjDo MVrJR|UxKD1iMD6wNFU2KM7:TR?= MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDh3MkK4NUc,OjR6NUKyPFE9N2F-
HeLa MnvtRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MUHJR|UxKD1iMD6wNFEzOSEQvF2= NYraT5pRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS4PVA3PTJpPkK0PFkxPjV{PD;hQi=>
MDA-MB-435 MmrBRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MlK0TWM2OCB;IECuNFAyQTNizszN MlnWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6OUC2OVIoRjJ2OEmwOlUzRC:jPh?=
SKOV3 NWr5VYM4SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MVvJR|UxKD1iMD6wNFMh|ryP MXK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDh7ME[1Nkc,OjR6OUC2OVI9N2F-
SKOV3 NEnMTWhEgXSxdH;4bYNqfHliYYPzZZk> NHTwWFhIUTVyIE2gNE4xODR5IN88US=> MojSQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR6OUOyNlQoRjJ2OEmzNlI1RC:jPh?=
P-gp expressing SKOV3-M6/6 M3\VdWN6fG:2b4jpZ4l1gSCjc4PhfS=> NIX5PVJIUTVyIE2gNE43KM7:TR?= M2D5Z|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OEmzNlI1Lz5{NEi5N|IzPDxxYU6=
PC3 NF3rS4REgXSxdH;4bYNqfHliYYPzZZk> MlHVPVYhcA>? MmDBTWM2OCB;IECuNFAzPSEQvF2= MnvLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MEC0N|coRjJ2OUCwOFM4RC:jPh?=
HeLa NGXpc|NIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVXSUJk1QTZiaB?= NHXBc4NKSzVyIE2gNE4xODV|IN88US=> NH[0O|Q9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEmwNFg3PSd-MkS5NFA5PjV:L3G+
OVCAR8 MVjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MW[5OkBp MnrITWM2OCB;IECuNFEh|ryP NXqwfI5mRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5NFA5PjVpPkK0PVAxQDZ3PD;hQi=>
NCI/ADR-RES M3LQ[Gdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MVO5OkBp NY\OVVEzUUN3MDC9JFUh|ryP Mm\VQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7MEC4OlUoRjJ2OUCwPFY2RC:jPh?=
MCF7 MofsR5l1d3SxeHnjbZR6KGG|c3H5 Mn63O|IhcA>? NEfDOJpKSzVyIE2gNE4xPDVizszN MWK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl{OUO0OEc,OjR7MkmzOFQ9N2F-
HCT116 M4jlbmN6fG:2b4jpZ4l1gSCjc4PhfS=> Mk[xO|IhcA>? Mlr4TWM2OCB;IECuNFY6KM7:TR?= NF3UOVU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEmyPVM1PCd-MkS5Nlk{PDR:L3G+
HepG2 NEO5NmREgXSxdH;4bYNqfHliYYPzZZk> NILPXpU4OiCq M3L2NmlEPTBiPTCwMlA5PCEQvF2= NWCwZlRURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5Nlk{PDRpPkK0PVI6OzR2PD;hQi=>
HeLa MV;DfZRwfG:6aXPpeJkh[XO|YYm= NHfDcnc4OiCq NUT4elRxUUN3MDC9JFAvODl4IN88US=> M3XrXVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUK5N|Q1Lz5{NEmyPVM1PDxxYU6=
U251 MXHDfZRwfG:6aXPpeJkh[XO|YYm= NXvGVI9lPzJiaB?= MkL4TWM2OCB;IECuNVI5KM7:TR?= M{LEb|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUK5N|Q1Lz5{NEmyPVM1PDxxYU6=
HT-29 MVHDfZRwfG:6aXPpeJkh[XO|YYm= MoG0TWM2OCB;IECuNFAyKM7:TR?= MlTrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7M{eyNFkoRjJ2OUO3NlA6RC:jPh?=
HT-29 NGPQU5JCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MnH4NlQh[W6mIEeyJIg> MUfJR|UxKD1iMD6yPUDPxE1? NGm2S5k9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm0NVE{OCd-MkS5OFEyOzB:L3G+
HeLa NYDTcXpUSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3rVS|I1KGGwZDC3NkBp Mlz1TWM2OCB;IECuNlkh|ryP NX7nfFV5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OFEyOzBpPkK0PVQyOTNyPD;hQi=>
Caco2 M4LGcmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MUWyOEBidmRiN{KgbC=> NVPZR|ZXUUN3MDC9JFAvOzFizszN NFfrSIg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm0NVE{OCd-MkS5OFEyOzB:L3G+
HL60 MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NH[0UWMzPCCjbnSgO|IhcA>? NFnDOGlKSzVyIE2gNE4{OiEQvF2= MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl2MUGzNEc,OjR7NEGxN|A9N2F-
MCF7 MnXrRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NWXKZ2FNOjRiYX7kJFczKGh? MmToTWM2OCB;IECuN|Mh|ryP MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl2MUGzNEc,OjR7NEGxN|A9N2F-
Saos2 MmPsRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NHTxR4UzPCCjbnSgO|IhcA>? M4XGPWlEPTBiPTCwMlM2KM7:TR?= M2PxRlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OUSxNVMxLz5{NEm0NVE{ODxxYU6=
SKOV3-MDR1-M6/6 NWr0dVVGSW62aXPhcoNmeiCjc4PhfS=> NIrUPGw1QCCq M4jLSGlEPTBiPTCwMlk4KM7:TR?= NWS2XZp6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OFYyPDVpPkK0PVQ3OTR3PD;hQi=>
SKOV3 MlHNRY51cWOjbnPldkBie3OjeR?= MmDrOFghcA>? M{fYUmlEPTBiPTCxJO69VQ>? NF2zPIc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm0OlE1PSd-MkS5OFYyPDV:L3G+
MDA435/LCC6 MoDlR5l1d3SxeHnjbZR6KGG|c3H5 NVnTbI1MPSCmYYnz M1uwdWlEPTBiPTCwMlAxOjZizszN MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl3MkO3Okc,OjR7NUKzO|Y9N2F-
MDA435/LCC6MDR NEG1[llEgXSxdH;4bYNqfHliYYPzZZk> Mn2zOUBl[Xm| MXTJR|UxKD1iMD6xOFk{KM7:TR?= NWnGZm1QRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5OVI{PzZpPkK0PVUzOzd4PD;hQi=>
MCF7 M4HoZ2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWHVWZZYUUN3MDC9JFAvODBzNTFOwG0> NH7iUGM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm2NFE1Oyd-MkS5OlAyPDN:L3G+
HepG2 M3TkV2N6fG:2b4jpZ4l1gSCjc4PhfS=> MVXJR|UxKD1iMD6wNFQ3KM7:TR?= NF;2UHg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm2NFE1Oyd-MkS5OlAyPDN:L3G+
MDA-MB-231 M{S5[mN6fG:2b4jpZ4l1gSCjc4PhfS=> M1yzRmlEPTBiPTCwMlAxQDJizszN M1ft[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ2OU[wNVQ{Lz5{NEm2NFE1OzxxYU6=
HL7702 MV;DfZRwfG:6aXPpeJkh[XO|YYm= M1zMO2lEPTBiPTCxMlEh|ryP NHfmdY09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NEm2NFE1Oyd-MkS5OlAyPDN:L3G+
MCF7 MWjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NF7NWVE1QCCq MVrJR|UxKD1iMD6wNlU5OSEQvF2= Mn;zQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjR7OU[xN|YoRjJ2OUm2NVM3RC:jPh?=
HepG2 M1rYbWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 Mne4OFghcA>? M3nReWlEPTBiPTCwMlA3PzJ5IN88US=> MUS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPDl7NkGzOkc,OjR7OU[xN|Y9N2F-
A549 M{LISWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M2jxclQ5KGh? Mn7JTWM2OCB;IEGuOVI2KM7:TR?= NWDXV4dKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkS5PVYyOzZpPkK0PVk3OTN4PD;hQi=>
KB NUfLdHFVS3m2b4TvfIlkcXS7IHHzd4F6 NHfwTos4OiCq NGLWSFNKSzVyIE2gNE4xODN7IN88US=> M4fYflxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEC4OFU3Lz5{NUCwPFQ2PjxxYU6=
A549 M1jVZWN6fG:2b4jpZ4l1gSCjc4PhfS=> NHrrS5E4OiCq NYTkXmpHUUN3MDC9JFAvODB3NzFOwG0> NHvkNoY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUCwPFQ2Pid-MkWwNFg1PTZ:L3G+
MDA-MB-231 NHjUVWlEgXSxdH;4bYNqfHliYYPzZZk> MVW3NkBp NWr3[WxWUUN3MDC9JFAvODB4NjFOwG0> NWTJXGhZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNFg1PTZpPkK1NFA5PDV4PD;hQi=>
KBVIN NVS3W|ZCS3m2b4TvfIlkcXS7IHHzd4F6 MlXnO|IhcA>? M1rQfGlEPTBiPTCxMlQ1KM7:TR?= NH3nXWU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUCwPFQ2Pid-MkWwNFg1PTZ:L3G+
MESSA NX\OVFNYS3m2b4TvfIlkcXS7IHHzd4F6 NFPnVGU4OiCq MULJR|UxKD1iMD6wNFQh|ryP M3vIPFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEK1PVkyLz5{NUCyOVk6OTxxYU6=
OVCAR8 MmDqR5l1d3SxeHnjbZR6KGG|c3H5 MUC5OkBp NHrCcohKSzVyIE2gNE4xODVizszN NHXObnU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUCyOVk6OSd-MkWwNlU6QTF:L3G+
MESSA/DX5 MVzDfZRwfG:6aXPpeJkh[XO|YYm= MoflO|IhcA>? M3:yS2lEPTBiPTCxMlc3PCEQvF2= M{O2R|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEK1PVkyLz5{NUCyOVk6OTxxYU6=
HepG2 MUTDfZRwfG:6aXPpeJkh[XO|YYm= NYnNcndzPDhiaB?= MoLBTWM2OCB;IEKuNFM4KM7:TR?= NX[3UoNURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwNlU6QTFpPkK1NFI2QTlzPD;hQi=>
NCI/ADR-RES MkS0R5l1d3SxeHnjbZR6KGG|c3H5 NITlSYQ6PiCq NY\TN|RzUUN3MDC9JFMvOyEQvF2= MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB{NUm5NUc,OjVyMkW5PVE9N2F-
PC3 NFjmNopEgXSxdH;4bYNqfHliYYPzZZk> NYC4eowxPDhiaB?= M{L0NmlEPTBiPTCzMlk6KM7:TR?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB{NUm5NUc,OjVyMkW5PVE9N2F-
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A2780 M4O1S2N6fG:2b4jpZ4l1gSCjc4PhfS=> NHLISnFKSzVyIE2gNE4xODB2IN88US=> NHTXTJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC0O|k{QCd-MkWwOFc6Ozh:L3G+
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SW480 M1j4PWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NHXkOJY1QCCq M{fXdmlEPTBiPTCwMlAxPyEQvF2= Mly0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNkG4NFMoRjJ3ME[xPFA{RC:jPh?=
A2780 MmPORY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MlXkOFghcA>? NFf3TIZKSzVyIE2gNE4xOTVizszN Mn\qQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNkG4NFMoRjJ3ME[xPFA{RC:jPh?=
HCT8 NHvlUIdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NXrvbGg{PDhiaB?= MnX1TWM2OCB;IECuNFIyKM7:TR?= Mn7uQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyNkG4NFMoRjJ3ME[xPFA{RC:jPh?=
MCF7 MnvCRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MlvXOFghcA>? MXjJR|UxKD1iMD6wNlMh|ryP MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB4MUiwN{c,OjVyNkG4NFM9N2F-
HepG2 NGjrO29CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MYO0PEBp MV\JR|UxKD1iMD6wNlgh|ryP MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB4MUiwN{c,OjVyNkG4NFM9N2F-
MCF7 NUnsSmxSS3m2b4TvfIlkcXS7IHHzd4F6 NVnVXohXPDhiaB?= MorZTWM2OCB;IECuNFA1KM7:TR?= NYXrRW1IRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwPFQyPDRpPkK1NFg1OTR2PD;hQi=>
A549 M4HnbmN6fG:2b4jpZ4l1gSCjc4PhfS=> NXXPe5dWPDhiaB?= NWf4Nm9YUUN3MDC9JFAvODh{IN88US=> MkG1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyOESxOFQoRjJ3MEi0NVQ1RC:jPh?=
COLO205 NHS5do5EgXSxdH;4bYNqfHliYYPzZZk> MkTxTWM2OCB;IECuNFA{KM7:TR?= M3[xWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MEmxPVI3Lz5{NUC5NVkzPjxxYU6=
K562 MX;DfZRwfG:6aXPpeJkh[XO|YYm= M4DJ[VczKGh? Mn7STWM2OCB;IECuNFA1KM7:TR?= NFviV2I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC5NVkzPid-MkWwPVE6OjZ:L3G+
A431 M4P5OGN6fG:2b4jpZ4l1gSCjc4PhfS=> MVu3NkBp MWrJR|UxKD1iMD6wNFch|ryP NX;wbZpuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwPVE6OjZpPkK1NFkyQTJ4PD;hQi=>
MDA-MB-435S NYfrZmx5S3m2b4TvfIlkcXS7IHHzd4F6 NHjTfZU4OiCq NW[1Zm5FUUN3MDC9JFAvODB7IN88US=> NIL3RoU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC5NVkzPid-MkWwPVE6OjZ:L3G+
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HepG2 NVrtPZRuS3m2b4TvfIlkcXS7IHHzd4F6 NV7nSFh6PzJiaB?= MmrFTWM2OCB;IECuPVkh|ryP MkHEQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyOUG5NlYoRjJ3MEmxPVI3RC:jPh?=
MDA-MB-DYT2 NHvFRplEgXSxdH;4bYNqfHliYYPzZZk> MX20JIRigXN? MlHSTWM2OCB;IECuNFA3ODhizszN MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTB7OEWyPEc,OjVyOUi1Nlg9N2F-
MDA-MB-468 M3q0NmN6fG:2b4jpZ4l1gSCjc4PhfS=> MYO0JIRigXN? MVTJR|UxKD1iMD6wNFcyPyEQvF2= NWezPW1{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWwPVg2OjhpPkK1NFk5PTJ6PD;hQi=>
NCI-N87 MVPDfZRwfG:6aXPpeJkh[XO|YYm= Mkm5OEBl[Xm| M1zySGlEPTBiPTCwMlAxPzV|IN88US=> NETOTZA9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC5PFUzQCd-MkWwPVg2Ojh:L3G+
NCI-H1975 NUHtSm1US3m2b4TvfIlkcXS7IHHzd4F6 Mn;VOEBl[Xm| MWfJR|UxKD1iMD6wNFc6PCEQvF2= MoS5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVyOUi1NlgoRjJ3MEm4OVI5RC:jPh?=
BT474 MVfDfZRwfG:6aXPpeJkh[XO|YYm= MkjDOEBl[Xm| NHnaNVNKSzVyIE2gNE4xODh|NjFOwG0> NFzvdYQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUC5PFUzQCd-MkWwPVg2Ojh:L3G+
DU145 NIDWdXZEgXSxdH;4bYNqfHliYYPzZZk> MnPWTWM2OCB;IEGuOUDPxE1? MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTFyNUeyNkc,OjVzMEW3NlI9N2F-
MCF7 MYDDfZRwfG:6aXPpeJkh[XO|YYm= M3XkfmlEPTBiPTCxMlgh|ryP MnLrQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVzMEW3NlIoRjJ3MUC1O|IzRC:jPh?=
HeLa NVOwNpFZS3m2b4TvfIlkcXS7IHHzd4F6 MmrWTWM2OCB;IEWg{txO Mn;iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjVzMEW3NlIoRjJ3MUC1O|IzRC:jPh?=
MCF7 MkTZR5l1d3SxeHnjbZR6KGG|c3H5 MkGwOFghcA>? NEG3V4pKSzVyIE2gNE4zKM7:TR?= NVznNIVzRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWxO|Y{OjlpPkK1NVc3OzJ7PD;hQi=>
NCI-H358 NFjTSXhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NIizVok1QCCq NX\IfolRUUN3MDC9JFAvODB{IN88US=> MlHlQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MEizOFUoRjJ3MkC4N|Q2RC:jPh?=
A2780S M1zDRWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NHrHWog1QCCq NWDJRZByUUN3MDC9JFAvODB2IN88US=> MlLwQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MEizOFUoRjJ3MkC4N|Q2RC:jPh?=
HCT8 NVzTVogzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= Mn;BOFghcA>? NWLzd2lqUUN3MDC9JFAvODB3IN88US=> MnHFQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MEizOFUoRjJ3MkC4N|Q2RC:jPh?=
AGS MmLURY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NV31V2szPDhiaB?= NUfIWohOUUN3MDC9JFAvODB6IN88US=> NH;POog9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUKwPFM1PSd-MkWyNFg{PDV:L3G+
DLD1 M2O3SWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MoDQOFghcA>? MVnJR|UxKD1iMD6wNVYh|ryP NFSzeVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUKwPFM1PSd-MkWyNFg{PDV:L3G+
HCT116 NHK3OJlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NVjrZVJyPDhiaB?= NYDGeJFGUUN3MDC9JFAvODF6IN88US=> NUXRdFM4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyNFg{PDVpPkK1NlA5OzR3PD;hQi=>
ES2 MlfwRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NEjuR5g1QCCq Mn3rTWM2OCB;IECuNFIh|ryP MkHiQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MEizOFUoRjJ3MkC4N|Q2RC:jPh?=
U251 M3S2VGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M2mxOVQ5KGh? NX62VIpwUUN3MDC9JFAvODJ|IN88US=> M1L2c|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3MkC4N|Q2Lz5{NUKwPFM1PTxxYU6=
HCT15 MVPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MUC0PEBp NHH6WlRKSzVyIE2gNE4xOjRizszN NVH2XohFRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyNFg{PDVpPkK1NlA5OzR3PD;hQi=>
HepG2 M{fq[GFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NWHyPFE5PDhiaB?= NGjNcIZKSzVyIE2gNE4xOzhizszN NVuxfow1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyNFg{PDVpPkK1NlA5OzR3PD;hQi=>
MCF7 MX7BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MorvOFghcA>? M1TTd2lEPTBiPTCwMlE{OiEQvF2= NW\5WWZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkWyNFg{PDVpPkK1NlA5OzR3PD;hQi=>
C26 NF\0UG5CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NFfucXM1QCCq NF\SS4RKSzVyIE2gNE4zOSEQvF2= MnXjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MEizOFUoRjJ3MkC4N|Q2RC:jPh?=
HL60 NGjXc5dEgXSxdH;4bYNqfHliYYPzZZk> M1vpclQ5KGh? NHjEZoFKSzVyIE2gNU42KM7:TR?= MmL1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV{MUGwN|IoRjJ3MkGxNFMzRC:jPh?=
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HL60 NIXEdIFEgXSxdH;4bYNqfHliYYPzZZk> M37jeVczKGh? M2PuTmlEPTBiPTCwMlAxOThizszN NWrp[ohmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVkxQTZpPkK1PFE6ODl4PD;hQi=>
MOLT4 NUTtdI1CS3m2b4TvfIlkcXS7IHHzd4F6 MnroO|IhcA>? NF\OZWRKSzVyIE2gNE4xODJ{IN88US=> M{XmO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEG5NFk3Lz5{NUixPVA6PjxxYU6=
U937 NUiyR5Q{S3m2b4TvfIlkcXS7IHHzd4F6 MU[3NkBp MlzZTWM2OCB;IECuNFAzPSEQvF2= NIPHOZU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUixPVA6Pid-MkW4NVkxQTZ:L3G+
HeLa M3\vSWN6fG:2b4jpZ4l1gSCjc4PhfS=> NIXKboE4OiCq MYTJR|UxKD1iMD6wNFMzKM7:TR?= NXzMbYxbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVkxQTZpPkK1PFE6ODl4PD;hQi=>
DU145 MnnmR5l1d3SxeHnjbZR6KGG|c3H5 NHP3c404OiCq NH:xe3hKSzVyIE2gNE4xODN2IN88US=> NWXUSGxjRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVkxQTZpPkK1PFE6ODl4PD;hQi=>
A549 NWS2UZh2S3m2b4TvfIlkcXS7IHHzd4F6 MkLjO|IhcA>? Mn\NTWM2OCB;IECuNFA1PCEQvF2= NX72XXZlRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4NVkxQTZpPkK1PFE6ODl4PD;hQi=>
SGC7901 MUDDfZRwfG:6aXPpeJkh[XO|YYm= MYW3NkBp NXPhUHhFUUN3MDC9JFAvODB3MTFOwG0> NFixco89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUixPVA6Pid-MkW4NVkxQTZ:L3G+
K562 NXfpSllxS3m2b4TvfIlkcXS7IHHzd4F6 MnW1O|IhcA>? NYDzZXhyUUN3MDC9JFAvODB3MjFOwG0> M2npO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEG5NFk3Lz5{NUixPVA6PjxxYU6=
MCF7 M2nIUWN6fG:2b4jpZ4l1gSCjc4PhfS=> MV23NkBp NU\nTI5SUUN3MDC9JFAvODB4MjFOwG0> MljjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUmwPVYoRjJ3OEG5NFk3RC:jPh?=
NCI-H1975 M3rCS2N6fG:2b4jpZ4l1gSCjc4PhfS=> NEjBOGc4OiCq NV7EeGFoUUN3MDC9JFAvODB5NzFOwG0> M{TCeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEG5NFk3Lz5{NUixPVA6PjxxYU6=
MX1 MUHDfZRwfG:6aXPpeJkh[XO|YYm= NXe5WYxPPzJiaB?= MWPJR|UxKD1iMD6wNFU2QSEQvF2= MmPmQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUmzN|QoRjJ3OEG5N|M1RC:jPh?=
ID8 MWLDfZRwfG:6aXPpeJkh[XO|YYm= MkfZO|IhcA>? NUfVV|Z[UUN3MDC9JFAvODF|ODFOwG0> Mmf0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUmzN|QoRjJ3OEG5N|M1RC:jPh?=
L1210 M4XReWN6fG:2b4jpZ4l1gSCjc4PhfS=> NF7GZ5Q4OiCq NV\xSZdpUUN3MDC9JFAvODJ5NjFOwG0> MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPThzOUOzOEc,OjV6MUmzN|Q9N2F-
WI38 NXf6eGptS3m2b4TvfIlkcXS7IHHzd4F6 MWO3NkBp MkHMTWM2OCB;IECuNFU2PyEQvF2= MoC1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6MUmzN|QoRjJ3OEG5N|M1RC:jPh?=
MDA-MB-231 NYm4XGtmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M4XPflQ5KGh? MVjHTVUxKD1iMD6wNUDPxE1? M2nYPVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEK3OVIzLz5{NUiyO|UzOjxxYU6=
A549 MXXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M2r1V|Q5KGh? MYfHTVUxKD1iMD6wNUDPxE1? M{CzSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEK3OVIzLz5{NUiyO|UzOjxxYU6=
PANC1 NEe0TpFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MVi0PEBp NXL2c|M4T0l3MDC9JFAvODF{IN88US=> NWSxdpB5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW4Nlc2OjJpPkK1PFI4PTJ{PD;hQi=>
HeLa Mn75RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MWO0PEBp NVTxRmdIT0l3MDC9JFAvODJizszN MlfXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6Mke1NlIoRjJ3OEK3OVIzRC:jPh?=
HEK293 MoPxR5l1d3SxeHnjbZR6KGG|c3H5 NFPEd3A4OiCq M3q2fmlEPTBiPTCwMlA1KM7:TR?= M2XZOFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OESyN|Y1Lz5{NUi0NlM3PDxxYU6=
SW480 NHPUTo9EgXSxdH;4bYNqfHliYYPzZZk> NYXvNpNOPDhiaB?= MYLJR|UxKD1iMD6wNFgh|ryP MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh5MUK2NUc,OjV6N{GyOlE9N2F-
HL60 MnzSR5l1d3SxeHnjbZR6KGG|c3H5 NF\lNmg1QCCq NXH5TlMzUUN3MDC9JFAvODB6IN88US=> MUm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh5MUK2NUc,OjV6N{GyOlE9N2F-
MCF7 M3Pk[GN6fG:2b4jpZ4l1gSCjc4PhfS=> M4S3WVQ5KGh? NFjEcVFKSzVyIE2gNE4xODhizszN NF7jU2s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUi3NVI3OSd-MkW4O|EzPjF:L3G+
SMMC7721 NV;X[5drS3m2b4TvfIlkcXS7IHHzd4F6 MnPGOFghcA>? MlznTWM2OCB;IECuNFA5KM7:TR?= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh5MUK2NUc,OjV6N{GyOlE9N2F-
A549 NEnJeGFEgXSxdH;4bYNqfHliYYPzZZk> NVLNc5RoPDhiaB?= NHHWbYlKSzVyIE2gNE4xODhizszN Ml7qQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6N{GyOlEoRjJ3OEexNlYyRC:jPh?=
SCC114 NEXYdYlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NVLPRZhrPzJiaB?= NHTRT5pKSzVyIE2gNE4xODB|IN88US=> Ml\oQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV6N{K5PFQoRjJ3OEeyPVg1RC:jPh?=
HeLa NV;FPGpmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NV\pfHI2PDhiaB?= MV7JR|UxKD1iMD6wNFE6KM7:TR?= M2[zWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEiyOVE6Lz5{NUi4NlUyQTxxYU6=
MDA-MB-435 M3K5W2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NIjKXXQ1QCCq NIfPWYlKSzVyIE2gNE4xODN|IN88US=> MYC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPTh6MkWxPUc,OjV6OEK1NVk9N2F-
SKOV3 MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? M4izbFQ5KGh? MUDJR|UxKD1iMD6wNFY{KM7:TR?= M1zCcVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEiyOVE6Lz5{NUi4NlUyQTxxYU6=
SKOV3-MDR1-M6/6 NXP4THh3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MV60PEBp NVm5b2ZFUUN3MDC9JFEvOTh5MjFOwG0> M2PzXlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OEiyOVE6Lz5{NUi4NlUyQTxxYU6=
A549 M2X2S2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NHjyXYM1QCCq M{HzdmlEPTBiPTCwMlAxOjNizszN NEPSd409[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUmzO|I{Pid-MkW5N|czOzZ:L3G+
taxol-resistant A549 NXvhcndvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MYS0PEBp Mo\aTWM2OCB;IECuOVIh|ryP M4\L[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUO3NlM3Lz5{NUmzO|I{PjxxYU6=
EL4 MnrpR5l1d3SxeHnjbZR6KGG|c3H5 MYO0PEBp NVXpdZNTUUN3MDC9JFEvPyEQvF2= NXrkSZFuRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkW5OVExPTdpPkK1PVUyODV5PD;hQi=>
HeLa NGP6XnRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHLxVXg1QCCq NWPSc5BtUUN3MDC9JFAvOzhizszN MnHNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7NUm4NVMoRjJ3OUW5PFE{RC:jPh?=
A549 MlvYRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NX3KOYpIPDhiaB?= NEXWb2JKSzVyIE2gNk45OiEQvF2= MoHvQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjV7NUm4NVMoRjJ3OUW5PFE{RC:jPh?=
LCC-6 M3TuOmN6fG:2b4jpZ4l1gSCjc4PhfS=> NHrjOGg{KGSjeYO= NGfabIVKSzVyIE2gNE4xODF4IN88US=> M4nCd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ3OUi1NVk2Lz5{NUm4OVE6PTxxYU6=
MDA435/LCC6MDR NYO4VZlsS3m2b4TvfIlkcXS7IHHzd4F6 MlfhN{Bl[Xm| NF7kVm9KSzVyIE2gNE4yPDR4IN88US=> NHm3No89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NUm4OVE6PSd-MkW5PFUyQTV:L3G+
A2780 Mn\ORY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M1zxZVIh\GG7cx?= M3LJdmlEPTBiPTCwMlAzQCEQvF2= MlP5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZyNEK0O|AoRjJ4MESyOFcxRC:jPh?=
SMMC7721 M1P0UmN6fG:2b4jpZ4l1gSCjc4PhfS=> MYW0PEBp MWDJR|UxKD1iMD6wNFgh|ryP NYrBPWM1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[wOlg5ODJpPkK2NFY5QDB{PD;hQi=>
HL60 MVzDfZRwfG:6aXPpeJkh[XO|YYm= MYe0PEBp MWXJR|UxKD1iMD6wNFgh|ryP M37YO|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4ME[4PFAzLz5{NkC2PFgxOjxxYU6=
MCF7 NXzR[JJ2S3m2b4TvfIlkcXS7IHHzd4F6 NIjMZY41QCCq MVfJR|UxKD1iMD6wNFgh|ryP MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjB4OEiwNkc,OjZyNki4NFI9N2F-
A549 NYTVXWRZS3m2b4TvfIlkcXS7IHHzd4F6 NXHzO217PDhiaB?= MYfJR|UxKD1iMD6wNFgh|ryP MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjB4OEiwNkc,OjZyNki4NFI9N2F-
SW480 M2T5dGN6fG:2b4jpZ4l1gSCjc4PhfS=> MWO0PEBp MYTJR|UxKD1iMD6wNFgh|ryP MlnOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZyNki4NFIoRjJ4ME[4PFAzRC:jPh?=
BEAS2B NVrOWZBUS3m2b4TvfIlkcXS7IHHzd4F6 MVG0PEBp NHnoZVRKSzVyIE2gNE42QCEQvF2= NFnT[4s9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkC2PFgxOid-Mk[wOlg5ODJ:L3G+
NB4 MlPXR5l1d3SxeHnjbZR6KGG|c3H5 M2q4Z|Q5KGh? M4fG[2lEPTBiPTCwMlAxOjNizszN NFe4emw9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
NCI-H1975 NH3uTVZEgXSxdH;4bYNqfHliYYPzZZk> NEjtbYk4OiCq MmTxTWM2OCB;IECuNFAzPSEQvF2= NVLxfHhyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
OVCAR8 MUfDfZRwfG:6aXPpeJkh[XO|YYm= M4HDdFQ5KGh? M321N2lEPTBiPTCwMlAxOzdizszN NGO4V489[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
MESSA NVrmVmJ5S3m2b4TvfIlkcXS7IHHzd4F6 MUG3NkBp M{XvXmlEPTBiPTCwMlAxPCEQvF2= NGGxeoc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkGzNlA4PSd-Mk[xN|IxPzV:L3G+
MDA-MB-468 NXrlS2pnS3m2b4TvfIlkcXS7IHHzd4F6 NVrNWIdpPzJiaB?= MlnDTWM2OCB;IECuNFA2KM7:TR?= M2TybVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
A549 M3:4OmN6fG:2b4jpZ4l1gSCjc4PhfS=> MmLjO|IhcA>? NGe4fGNKSzVyIE2gNE4xODdizszN M3z5TFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
MDA-MB-231 M1X4fmN6fG:2b4jpZ4l1gSCjc4PhfS=> MorIO|IhcA>? NX32WldHUUN3MDC9JFAvODB5IN88US=> NYLseJY4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
MDA-MB-436 M134emN6fG:2b4jpZ4l1gSCjc4PhfS=> MmXOO|IhcA>? MWPJR|UxKD1iMD6wNFgh|ryP NXvZcmR{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
MESSA/DX5 MVnDfZRwfG:6aXPpeJkh[XO|YYm= NF:3WVc4OiCq NHPFNYZKSzVyIE2gNU44PjRizszN M2fUS|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
HepG2 MYnDfZRwfG:6aXPpeJkh[XO|YYm= NYPBTG5qPDhiaB?= NYHOOplqUUN3MDC9JFIvPiEQvF2= NUS0[255RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xN|IxPzVpPkK2NVMzODd3PD;hQi=>
PC3 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NFXuOWU1QCCq MVXJR|UxKD1iND65JO69VQ>? M1\VdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4MUOyNFc2Lz5{NkGzNlA4PTxxYU6=
NCI-ADR-RES MXjDfZRwfG:6aXPpeJkh[XO|YYm= MXe0PEBp NF;PS|dKSzVyIE2gOkDPxE1? MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjF|MkC3OUc,OjZzM{KwO|U9N2F-
KB NFz5NmZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NGXiWpc4OiCq NFfhUFNKSzVyIE2gNE4xODVzIN88US=> NYfhZpJRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xOlAxOjBpPkK2NVYxODJyPD;hQi=>
KB-7d NHrTZpFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MXO3NkBp NYPM[Xl{UUN3MDC9JFAvODB6NDFOwG0> NUfyc5p{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[xOlAxOjBpPkK2NVYxODJyPD;hQi=>
KB-S15 MUPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NV60W2FOPzJiaB?= M2jYd2lEPTBiPTCwMlE{PSEQvF2= MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjF4MECyNEc,OjZzNkCwNlA9N2F-
DU145 NH3MdWpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M4DVV2dKPTBiPTCwMlAxPiEQvF2= NYjFS3dGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[yOFIzPDJpPkK2NlQzOjR{PD;hQi=>
KB NH;X[4pCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NULlZ41OT0l3MDC9JFAvODB4NDFOwG0> NF;DeFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK0NlI1Oid-Mk[yOFIzPDJ:L3G+
A549 NF\oNIFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MUXHTVUxKD1iMD6wNFc3KM7:TR?= NGjDblc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkK0NlI1Oid-Mk[yOFIzPDJ:L3G+
vincristine-resistant KBVIN NXniZYUzSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NHX5SldIUTVyIE2gNU4zOSEQvF2= MoO1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ{NEKyOFIoRjJ4MkSyNlQzRC:jPh?=
K562 M3SyfmN6fG:2b4jpZ4l1gSCjc4PhfS=> NEfsc4JKSzVyIE2gNE46KM7:TR?= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjJ6N{SwNUc,OjZ{OEe0NFE9N2F-
U937 M4fxO2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYe3NkBp NWXNU|FRUUN3MDC9JFIvOSEQvF2= M3HQW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4M{G2OFY4Lz5{NkOxOlQ3PzxxYU6=
A549 MkG0R5l1d3SxeHnjbZR6KGG|c3H5 MmftO|IhcA>? MYLJR|UxKD1iMj6xJO69VQ>? MkLJQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ|MU[0OlcoRjJ4M{G2OFY4RC:jPh?=
MCF7 MXHDfZRwfG:6aXPpeJkh[XO|YYm= MUi3NkBp NGrue45KSzVyIE2gNk4{KM7:TR?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNzNkS2O{c,OjZ|MU[0Olc9N2F-
MOLT4 MlXzR5l1d3SxeHnjbZR6KGG|c3H5 MUe3NkBp NVi2V25WUUN3MDC9JFIvPyEQvF2= MWC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNzNkS2O{c,OjZ|MU[0Olc9N2F-
NCI-H1975 NHvPNo1EgXSxdH;4bYNqfHliYYPzZZk> MmLRO|IhcA>? NELoWWFKSzVyIE2gNk45KM7:TR?= NH20R3E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
HeLa NWKxUVdpS3m2b4TvfIlkcXS7IHHzd4F6 NVrkS2hUPzJiaB?= MmSzTWM2OCB;IEKuPUDPxE1? MXm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNzNkS2O{c,OjZ|MU[0Olc9N2F-
DU145 M13ve2N6fG:2b4jpZ4l1gSCjc4PhfS=> NEHxNXU4OiCq NUPJWI5XUUN3MDC9JFMvOSEQvF2= MlO4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ|MU[0OlcoRjJ4M{G2OFY4RC:jPh?=
K562 NH\hSFBEgXSxdH;4bYNqfHliYYPzZZk> Ml;SO|IhcA>? NFexT|BKSzVyIE2gN{45KM7:TR?= NVP5ZoV6RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[zNVY1PjdpPkK2N|E3PDZ5PD;hQi=>
HL60 NXWzXY5KS3m2b4TvfIlkcXS7IHHzd4F6 NIHYTJo4OiCq MnO2TWM2OCB;IEOuPEDPxE1? MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjNzNkS2O{c,OjZ|MU[0Olc9N2F-
SGC7901 M{n5ZmN6fG:2b4jpZ4l1gSCjc4PhfS=> M4LlVFczKGh? Ml\STWM2OCB;IEmuPEDPxE1? NEK3VHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkOxOlQ3Pyd-Mk[zNVY1Pjd:L3G+
MES-SA MkLsR5l1d3SxeHnjbZR6KGG|c3H5 NFjGT3M1QCCq NGOwdIFIUTVyIE2gNE4xODdizszN NHvZSlI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkO2NFA1Pyd-Mk[zOlAxPDd:L3G+
Rhabdomyosarcoma NFPLdlhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NVrNU2xqQTZiaB?= MV\JR|UxKD1iMD6wNFg1KM7:TR?= Ml7yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ|OE[4NVgoRjJ4M{i2PFE5RC:jPh?=
HT-29 MlPaR5l1d3SxeHnjbZR6KGG|c3H5 NIHvXHA{KGSjeYO= MWfJR|UxKD1iMD6wNFA5KM7:TR?= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjR{MkGzNUc,OjZ2MkKxN|E9N2F-
MDA-MB-231 MUXDfZRwfG:6aXPpeJkh[XO|YYm= NYHRUZIyPzJiaB?= NV7TUmg4UUN3MDC9JFAvODBzIN88US=> NEnIb|Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkS0PFA{Pyd-Mk[0OFgxOzd:L3G+
PC3 NULCVlgyS3m2b4TvfIlkcXS7IHHzd4F6 MoX0O|IhcA>? M2PMUWlEPTBiPTCwMlAxOSEQvF2= NEnhOno9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkS0PFA{Pyd-Mk[0OFgxOzd:L3G+
HCT116 MX3DfZRwfG:6aXPpeJkh[XO|YYm= M1zZPVQ5KGh? MmH2TWM2OCB;IECuNFAzQCEQvF2= NUDxNYVqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[0OFgxOzdpPkK2OFQ5ODN5PD;hQi=>
A549 M{jDXWN6fG:2b4jpZ4l1gSCjc4PhfS=> MoLGTWM2OCB;IECuNFA3OyEQvF2= Mlv4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ2NEiwN|coRjJ4NES4NFM4RC:jPh?=
HepG2 NH;XcIVEgXSxdH;4bYNqfHliYYPzZZk> NXfCco1pPDhiaB?= M4PaTGlEPTBiPTCxMlIyPyEQvF2= M2OzW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NES4NFM4Lz5{NkS0PFA{PzxxYU6=
H460 NV;1XHpWS3m2b4TvfIlkcXS7IHHzd4F6 MXK0PEBp NHTveGhKSzVyIE2gOE4zQDdizszN M{\4SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NES4NFM4Lz5{NkS0PFA{PzxxYU6=
cells after 48 hrs by SRB assay NH\LO45EgXSxdH;4bYNqfHliYYPzZZk> M1H4eWdKPTBiPTCwMlAxOTR6IN88US=> NH;RcIo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{NkS2NlA2Oid-Mk[0OlIxPTJ:L3G+
HeLa M4n3SmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MVS3NkBp NFvPb2ZKSzVyIE2gNk4zQSEQvF2= NITuVo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[wNlgzPyd-Mk[2NFI5Ojd:L3G+
184B5 NGnzc|BCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NYHHZWJLPzJiaB?= NXXQ[5JtUUN3MDC9JFIvOzJizszN M365WVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkCyPFI4Lz5{Nk[wNlgzPzxxYU6=
MDA-MB-231 M{j1ZmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MXe3NkBp NYn2SYFPUUN3MDC9JFIvPTZizszN NHjKZpE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[wNlgzPyd-Mk[2NFI5Ojd:L3G+
MDA-MB-468 Mli5RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MmfpO|IhcA>? MnnlTWM2OCB;IEOuPFch|ryP NIHsPVI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{Nk[wNlgzPyd-Mk[2NFI5Ojd:L3G+
MCF7 NFPLVFhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M2\ic|czKGh? M1G3SWlEPTBiPTCzMlk6KM7:TR?= MkLjQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ4MEK4NlcoRjJ4NkCyPFI4RC:jPh?=
Jurkat NX;TWZBnS3m2b4TvfIlkcXS7IHHzd4F6 M{[yN|Q5KGh? Ml3CTWM2OCB;IECuNFAxPSEQvF2= NXnHSphZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2N|gxPDFpPkK2OlM5ODRzPD;hQi=>
U937 MW\DfZRwfG:6aXPpeJkh[XO|YYm= MYm0PEBp MmPyTWM2OCB;IECuNFA3KM7:TR?= NVfsUmhMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2N|gxPDFpPkK2OlM5ODRzPD;hQi=>
HeLa MnexR5l1d3SxeHnjbZR6KGG|c3H5 MlTZOFghcA>? MYTJR|UxKD1iMD6wPVkh|ryP MUW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ|OEC0NUc,OjZ4M{iwOFE9N2F-
cells assessed as cell growth inhibition after 48 hrs by MTT assay M2TTfWN6fG:2b4jpZ4l1gSCjc4PhfS=> NEjKWohKSzVyIE2gNE43PSEQvF2= MXe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ|OEC0NUc,OjZ4M{iwOFE9N2F-
MDA-MB-231 MUjDfZRwfG:6aXPpeJkh[XO|YYm= MYS3NkBp M1HM[GlEPTBiPTCwMlAxOzlizszN M1PWUFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkmwNlc1Lz5{Nk[5NFI4PDxxYU6=
MCF7 MWPDfZRwfG:6aXPpeJkh[XO|YYm= NH:3dHg4OiCq NYHZPHhVUUN3MDC9JFAvODB5NDFOwG0> M3PT[lxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4NkmwNlc1Lz5{Nk[5NFI4PDxxYU6=
U937 MUjDfZRwfG:6aXPpeJkh[XO|YYm= M2LTXVczKGh? M134U2lEPTBiPTCwMlAxOTZ4IN88US=> MV28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ7N{exPEc,OjZ4OUe3NVg9N2F-
HL60 M4DsSWN6fG:2b4jpZ4l1gSCjc4PhfS=> NWfvd4dwPzJiaB?= MmrMTWM2OCB;IECuNFAyQTlizszN NYDDPVB5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2PVc4OThpPkK2Olk4PzF6PD;hQi=>
A549 M3\WbWN6fG:2b4jpZ4l1gSCjc4PhfS=> NGLoVpQ4OiCq NITWbI1KSzVyIE2gNE4xODJzMjFOwG0> M1r4TlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4Nkm3O|E5Lz5{Nk[5O|cyQDxxYU6=
DU145 MUXDfZRwfG:6aXPpeJkh[XO|YYm= MVy3NkBp MYLJR|UxKD1iMD6wNFI{KM7:TR?= M2n1VVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4Nkm3O|E5Lz5{Nk[5O|cyQDxxYU6=
HeLa MWDDfZRwfG:6aXPpeJkh[XO|YYm= MVm3NkBp NG\0RnhKSzVyIE2gNE4xODNyMTFOwG0> MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ7N{exPEc,OjZ4OUe3NVg9N2F-
HT-29 NHjhbGdEgXSxdH;4bYNqfHliYYPzZZk> M3G4bFczKGh? M4njPGlEPTBiPTCwMlAxOzB2IN88US=> NV7ERWNrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[2PVc4OThpPkK2Olk4PzF6PD;hQi=>
K562 MmnyR5l1d3SxeHnjbZR6KGG|c3H5 NVnGZ|R6PzJiaB?= MUTJR|UxKD1iMD6wNFcyPyEQvF2= MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ7N{exPEc,OjZ4OUe3NVg9N2F-
MCF7 MoKxR5l1d3SxeHnjbZR6KGG|c3H5 NELZUW44OiCq MmCyTWM2OCB;IECuNFA4OzJizszN MWO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjZ7N{exPEc,OjZ4OUe3NVg9N2F-
NCI-H292 MofLR5l1d3SxeHnjbZR6KGG|c3H5 M2rhTVczKGh? MlHFTWM2OCB;IECuNFA3KM7:TR?= MmDRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5MUKwPVgoRjJ4N{GyNFk5RC:jPh?=
KB NFf3WplIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3vmN|czKGh? NWXlXWRUT0l3MDC9JFAvODBzIN88US=> MoTXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ5N{i2NVIoRjJ4N{e4OlEzRC:jPh?=
DU145 MlHHRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MkHTOFghcA>? NIXrb4NKSzVyIE2gNE4xODN6IN88US=> MWe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjd6NUOwOkc,OjZ5OEWzNFY9N2F-
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A549 NVzsT2pwSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MXizJIRigXN? M4HBSmlEPTBiPTCwMlAxODB|IN88US=> M1jaUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ4OE[1NVc3Lz5{Nki2OVE4PjxxYU6=
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A549 NGjFNpBEgXSxdH;4bYNqfHliYYPzZZk> MVO0PEBp NFOzTJFKSzVyIE2gNE4xOTN{IN88US=> MlXXQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7OEWyPVYoRjJ4OUi1Nlk3RC:jPh?=
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HeLa M4T6V2N6fG:2b4jpZ4l1gSCjc4PhfS=> MYS0PEBp M1HBdWlEPTBiPTCwMlAyQDlizszN MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjl6NUK5Okc,OjZ7OEWyPVY9N2F-
WPMY-1 NULWXXVIS3m2b4TvfIlkcXS7IHHzd4F6 NWnnXpRsPDhiaB?= NES3[2lIUTVyIE2gNE4xOSEQvF2= NYTHSWFMRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[5PVQ3QTBpPkK2PVk1PjlyPD;hQi=>
A549 Mn7yRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MYC0PEBp NGHm[lNIUTVyIE2gNE4xOSEQvF2= Mlj5QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjZ7OUS2PVAoRjJ4OUm0OlkxRC:jPh?=
MDA-MB-231 NIrQTYtCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1vLSVQ5KGh? NHm4dmhIUTVyIE2gNE4xOSEQvF2= NXTpNmxRRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMk[5PVQ3QTBpPkK2PVk1PjlyPD;hQi=>
HeLa MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MXW0PEBp MnjNS2k2OCB;IECuNFI{KM7:TR?= MUG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPjl7NE[5NEc,OjZ7OUS2PVA9N2F-
HepG2 NFO2SVZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M3PUV|Q5KGh? MWTJR|UxKD1iMD6wNlE4OSEQvF2= NWHJbXJURGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkewNVczPjVpPkK3NFE4OjZ3PD;hQi=>
MCF7 M3TNOWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NX3BS4d1PDhiaB?= MknwTWM2OCB;IECuNFI2QDFizszN M{PEdVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MEG3NlY2Lz5{N{CxO|I3PTxxYU6=
HCT116 Ml:0RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M{XYRlQ5KGh? M1PpdWlEPTBiPTCwMlA3PzJ5IN88US=> NVLNU3BPRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkewNVczPjVpPkK3NFE4OjZ3PD;hQi=>
A2780 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NXvWbmY5PDhiaB?= MUTJR|UxKD1iMD6wNFUh|ryP MoHxQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzNEm2OFEoRjJ5MUS5OlQyRC:jPh?=
A549 M17YUGN6fG:2b4jpZ4l1gSCjc4PhfS=> NYm2[WE3PDhiaB?= MX7JR|UxKD1iMD6wNFkh|ryP MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzF2OU[0NUc,OjdzNEm2OFE9N2F-
MCF7 MWjDfZRwfG:6aXPpeJkh[XO|YYm= MYW0PEBp M2nrd2lEPTBiPTCwMlAyOiEQvF2= M2KzU|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUS5OlQyLz5{N{G0PVY1OTxxYU6=
HCT8 M2LaUmN6fG:2b4jpZ4l1gSCjc4PhfS=> M2LYWFQ5KGh? MmPFTWM2OCB;IECuNFE6KM7:TR?= M1i2flxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MUS5OlQyLz5{N{G0PVY1OTxxYU6=
A549/CDDP MmTYR5l1d3SxeHnjbZR6KGG|c3H5 NWry[GRbPDhiaB?= MlK1TWM2OCB;IECuNFI{KM7:TR?= NYe1V2JDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkexOFk3PDFpPkK3NVQ6PjRzPD;hQi=>
HCT8/VCT MWPDfZRwfG:6aXPpeJkh[XO|YYm= MYS0PEBp NXnlPWpbUUN3MDC9JFAvOTJ3IN88US=> Mn7ZQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjdzNEm2OFEoRjJ5MUS5OlQyRC:jPh?=
MCF7/DX M3\FOWN6fG:2b4jpZ4l1gSCjc4PhfS=> M160SlQ5KGh? MUPJR|UxKD1iMD6xN|Uh|ryP MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzF2OU[0NUc,OjdzNEm2OFE9N2F-
A2780/TAX MWHDfZRwfG:6aXPpeJkh[XO|YYm= NUjLPIdEPDhiaB?= MW\JR|UxKD1iNT62PEDPxE1? MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzF2OU[0NUc,OjdzNEm2OFE9N2F-
HeLa NFfB[GhCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NHrNbXo1QCCq NUTLbVRoT0l3MDC9JFAvODJ3IN88US=> MXG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzJyOUKzNkc,Ojd{MEmyN|I9N2F-
MiaPaCa M33zXGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NFfaNnY1QCCq NFvzPZdIUTVyIE2gNE4xPTZizszN MW[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzJyOUKzNkc,Ojd{MEmyN|I9N2F-
IMR32 NXzBV3loSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3\vflQ5KGh? MmixS2k2OCB;IECuNFc2KM7:TR?= MmT2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd{MEmyN|IoRjJ5MkC5NlMzRC:jPh?=
MDA-MB-231 NVXJS4h1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M{jMfVQ5KGh? NY\UemtpT0l3MDC9JFAvODlzIN88US=> MofUQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd{MEmyN|IoRjJ5MkC5NlMzRC:jPh?=
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MES-SA M4jYbmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NYnUe5IzPDhidH:gPVYhcA>? MYHHTVUxKD1iMD6wNFch|ryP M2f2XVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MkG4PFYxLz5{N{KxPFg3ODxxYU6=
NCI-H2073 NYe3NHJ3SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWrYd3Q1PDhidH:gPVYhcA>? NWLDS493T0l3MDC9JFIvPCEQvF2= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzJzOEi2NEc,Ojd{MUi4OlA9N2F-
KBVIN M3nlbGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NEi4S3U1QCCq NIrFXXlIUTVyIE2gNk43KM7:TR?= M4nE[FxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MkO4PFQzLz5{N{KzPFg1OjxxYU6=
A549 NG\0e3JCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MlnnOFghcA>? MW\HTVUxKD1iMj62JO69VQ>? M3PySVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5MkO4PFQzLz5{N{KzPFg1OjxxYU6=
MCF7 NVnITG9nS3m2b4TvfIlkcXS7IHHzd4F6 NGjwWXc4OiCq MX7JR|UxKD1iMD6wNFEzPSEQvF2= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzNzMUi5N{c,Ojd|MUG4PVM9N2F-
HeLa M3TtO2N6fG:2b4jpZ4l1gSCjc4PhfS=> M2fGb|czKGh? NFTpc3lKSzVyIE2gNE4xOTJ4MjFOwG0> MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzNzMUi5N{c,Ojd|MUG4PVM9N2F-
MDA-MB-231 NYjM[JdWSW62aXPhcoNmeiCjc4PhfS=> MYK3NkBp MmntTWM2OCB;IECuNFA{Ozh6IN88US=> NXLqZ3VJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkezNVc3PDVpPkK3N|E4PjR3PD;hQi=>
HeLa MUTBcpRq[2GwY3XyJIF{e2G7 NW[1fYZEPzJiaB?= M{TCTGlEPTBiPTCwMlAyQTh5IN88US=> MX68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzNzN{[0OUc,Ojd|MUe2OFU9N2F-
HT-29 M1v4e2N6fG:2b4jpZ4l1gSCjc4PhfS=> NWH1fnh5PzJiaB?= MkTrTWM2OCB;IECuNFIh|ryP Moi4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd|Mkm5N|goRjJ5M{K5PVM5RC:jPh?=
PC3 M{fDTWN6fG:2b4jpZ4l1gSCjc4PhfS=> Ml6wO|IhcA>? NIHyZVNKSzVyIE2gNE4xOyEQvF2= NXHGbGpORGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkezNlk6OzhpPkK3N|I6QTN6PD;hQi=>
HL-7702 M1y4bGN6fG:2b4jpZ4l1gSCjc4PhfS=> MX63NkBp NULpe5c{UUN3MDC9JFAvODZizszN NFTFZ409[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{OyPVk{QCd-MkezNlk6Ozh:L3G+
A549 MoT3R5l1d3SxeHnjbZR6KGG|c3H5 Mny0O|IhcA>? M1\ad2lEPTBiPTCwMlA5KM7:TR?= M3nRUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5M{K5PVM5Lz5{N{OyPVk{QDxxYU6=
HepG2 MXnDfZRwfG:6aXPpeJkh[XO|YYm= MlXCO|IhcA>? Mnq3TWM2OCB;IECuNkDPxE1? NFW0cos9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{OyPVk{QCd-MkezNlk6Ozh:L3G+
MCF7 MnHzR5l1d3SxeHnjbZR6KGG|c3H5 NF24bm46PiCq MWfJR|UxKD1iMD6wNFAzKM7:TR?= MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzR|NESyOkc,Ojd2M{S0NlY9N2F-
HeLa Mkf1R5l1d3SxeHnjbZR6KGG|c3H5 M3jQdFk3KGh? NGfwfIxKSzVyIE2gNE4xODZ2IN88US=> NVTMR5NIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke0N|Q1OjZpPkK3OFM1PDJ4PD;hQi=>
MCF7 NXX1T45XS3m2b4TvfIlkcXS7IHHzd4F6 MnnHTWM2OCB;IECuNFAxPiEQvF2= MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzR2MUi5Nkc,Ojd2NEG4PVI9N2F-
HCT116 MnL6R5l1d3SxeHnjbZR6KGG|c3H5 MojLTWM2OCB;IECuNFAxQSEQvF2= M4rzdFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NESxPFkzLz5{N{S0NVg6OjxxYU6=
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HepG2 MmizR5l1d3SxeHnjbZR6KGG|c3H5 NHnVfZBKSzVyIE2gNE4xOTJizszN M3[xWlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NESxPFkzLz5{N{S0NVg6OjxxYU6=
Capan2 MXfDfZRwfG:6aXPpeJkh[XO|YYm= M4e1UGlEPTBiPTCwMlAyPyEQvF2= NGDlelI9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{S0NVg6Oid-Mke0OFE5QTJ:L3G+
A375 NXPwXVZWS3m2b4TvfIlkcXS7IHHzd4F6 NG\Ec|dKSzVyIE2gNE4xOjJizszN NXS3W2Z5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke0OFE5QTJpPkK3OFQyQDl{PD;hQi=>
A549 MlKzR5l1d3SxeHnjbZR6KGG|c3H5 NVi5PFFQUUN3MDC9JFAvODJ|IN88US=> NH7jXoo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{S0NVg6Oid-Mke0OFE5QTJ:L3G+
A2780 Mn61R5l1d3SxeHnjbZR6KGG|c3H5 Mm[zTWM2OCB;IECuNFM5KM7:TR?= M3;TXFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NESxPFkzLz5{N{S0NVg6OjxxYU6=
NCI-H1650 NHHNW4VEgXSxdH;4bYNqfHliYYPzZZk> M{TGPWlEPTBiPTCwMlA3QCEQvF2= M3;UUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5NESxPFkzLz5{N{S0NVg6OjxxYU6=
NCI60 NHm0eW9EgXSxdH;4bYNqfHliYYPzZZk> NF7jb5E1QCCq MUfHTVUxKD1iMD6wN|E2KM7:TR?= NXniWWlqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke0OFg6OjRpPkK3OFQ5QTJ2PD;hQi=>
HepG2 MYHDfZRwfG:6aXPpeJkh[XO|YYm= NF3LWG01QCCq MXLJR|UxKD1iMD6wNFYh|ryP MlnWQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd4MkexN|AoRjJ5NkK3NVMxRC:jPh?=
Hep3B M3PqZWN6fG:2b4jpZ4l1gSCjc4PhfS=> MlHUOFghcA>? NHv4SI5KSzVyIE2gNE4xOiEQvF2= MXu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzZ{N{GzNEc,Ojd4MkexN|A9N2F-
A549 NWn1eYxYS3m2b4TvfIlkcXS7IHHzd4F6 NIrKZ3U1QCCq NH3tOWpKSzVyIE2gNE4xOyEQvF2= NWj0e|Z3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke2NlcyOzBpPkK3OlI4OTNyPD;hQi=>
MCF7 M2TGcGN6fG:2b4jpZ4l1gSCjc4PhfS=> M2LyNVQ5KGh? M3HveGlEPTBiPTCwMlA3KM7:TR?= NFTPUpY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{[yO|E{OCd-Mke2NlcyOzB:L3G+
A549 NYPxbJRJS3m2b4TvfIlkcXS7IHHzd4F6 MkPIOFghcA>? Ml71TWM2OCB;IECuNFA5KM7:TR?= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzdyNEiwO{c,Ojd5MES4NFc9N2F-
SW480 NFmwbJlEgXSxdH;4bYNqfHliYYPzZZk> NXLvc3RoPDhiaB?= MX3JR|UxKD1iMD6wNFgh|ryP MnnqQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5MES4NFcoRjJ5N{C0PFA4RC:jPh?=
HL60 MmLrR5l1d3SxeHnjbZR6KGG|c3H5 MXG0PEBp MlK2TWM2OCB;IECuNFA5KM7:TR?= NUTHOpdLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3NFQ5ODdpPkK3O|A1QDB5PD;hQi=>
SMMC7721 NHn2U3NEgXSxdH;4bYNqfHliYYPzZZk> M{jvZlQ5KGh? NX\rV3hLUUN3MDC9JFAvODB6IN88US=> NF\0NGQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{ewOFgxPyd-Mke3NFQ5ODd:L3G+
MCF7 NGXveVVEgXSxdH;4bYNqfHliYYPzZZk> MVO0PEBp NYXKcWpxUUN3MDC9JFAvODB6IN88US=> MVW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzdyNEiwO{c,Ojd5MES4NFc9N2F-
HeLa NHW3SWdEgXSxdH;4bYNqfHliYYPzZZk> M2\vdlQ5KGh? NHrnVlFKSzVyIE2gNE4xODhizszN NH;PW5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{ewOFgxPyd-Mke3NFQ5ODd:L3G+
A549 NEjGbZJEgXSxdH;4bYNqfHliYYPzZZk> MWS0PEBp NYTVdZJuUUN3MDC9JFAvODJizszN Mn7YQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5MES4NlIoRjJ5N{C0PFIzRC:jPh?=
MCF7 NHe0R|ZEgXSxdH;4bYNqfHliYYPzZZk> NYLSR2JsPDhiaB?= M1TWd2lEPTBiPTCwMlEh|ryP M1XkZVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{C0PFIzLz5{N{ewOFgzOjxxYU6=
HeLa Mkj3R5l1d3SxeHnjbZR6KGG|c3H5 MlvqO|IhcA>? MV7JR|UxKD1iMT63JO69VQ>? NGXlVHQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{e0PFU6PSd-Mke3OFg2QTV:L3G+
K562 M4XKZmN6fG:2b4jpZ4l1gSCjc4PhfS=> NVrWc4Z{PzJiaB?= MkX2TWM2OCB;IEKuO{DPxE1? MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd2OEW5OUc,Ojd5NEi1PVU9N2F-
HCT116 NHToZXlEgXSxdH;4bYNqfHliYYPzZZk> MVO3NkBp MWjJR|UxKD1iMz6zJO69VQ>? MVS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd2OEW5OUc,Ojd5NEi1PVU9N2F-
A549 NILmVVdEgXSxdH;4bYNqfHliYYPzZZk> MluzO|IhcA>? MmK5TWM2OCB;IEWuOUDPxE1? Mn7RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5NEi1PVUoRjJ5N{S4OVk2RC:jPh?=
HepG2 NYnwWHNzS3m2b4TvfIlkcXS7IHHzd4F6 NGDsfIw4OiCq MlnoTWM2OCB;IE[uO{DPxE1? M2mzZlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{S4OVk2Lz5{N{e0PFU6PTxxYU6=
HELF MUTDfZRwfG:6aXPpeJkh[XO|YYm= MV[yOEBp M4nmS2lEPTBiPTC3MlE1KM7:TR?= M4rET|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{[5NFMyLz5{N{e2PVA{OTxxYU6=
BGC823 NV2w[I5VS3m2b4TvfIlkcXS7IHHzd4F6 NYPjVJoyOjRiaB?= NYfPbm9WUUN3MDC9JFkvOjZizszN NUPSOYEyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke3OlkxOzFpPkK3O|Y6ODNzPD;hQi=>
KB Mly3R5l1d3SxeHnjbZR6KGG|c3H5 NHqxTIE1QCCq M2nzUWlEPTBiPTCwMlAxODhizszN MkS0QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd5OUexPVIoRjJ5N{m3NVkzRC:jPh?=
A549 MoHqR5l1d3SxeHnjbZR6KGG|c3H5 MYO0PEBp MU\JR|UxKD1iMD6wNFA6QSEQvF2= M17BTlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{m3NVkzLz5{N{e5O|E6OjxxYU6=
MDA-MB-231 Mn\2R5l1d3SxeHnjbZR6KGG|c3H5 NEDqW3k1QCCq NV74TGxJUUN3MDC9JFAvODB|MEWg{txO MVO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzd7N{G5Nkc,Ojd5OUexPVI9N2F-
MCF7 NHHjdlFEgXSxdH;4bYNqfHliYYPzZZk> M3TRdVQ5KGh? MnTZTWM2OCB;IECuNFIzPzVizszN M3OyfFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5N{m3NVkzLz5{N{e5O|E6OjxxYU6=
KBVIN MWLDfZRwfG:6aXPpeJkh[XO|YYm= MluzOFghcA>? NUXMfmVkUUN3MDC9JFEvQDl4IN88US=> NHvWWHU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{e5O|E6Oid-Mke3PVcyQTJ:L3G+
HCT116 MXPDfZRwfG:6aXPpeJkh[XO|YYm= MonIOFghcA>? MlLPTWM2OCB;IECuNUDPxE1? NGjidFY9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{i4O|g1Oyd-Mke4PFc5PDN:L3G+
Bel7402 M4DuS2N6fG:2b4jpZ4l1gSCjc4PhfS=> Mn:yOFghcA>? MYrJR|UxKD1iMD6xJO69VQ>? MWi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzh6N{i0N{c,Ojd6OEe4OFM9N2F-
OVCAR8 NFTFRYRIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVrGcIhiQTZiaB?= MnvhTWM2OCB;IEWg{txO M1zRcFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ5OEm0OVg6Lz5{N{i5OFU5QTxxYU6=
HeLa NX3tNXZxT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkC5PVYhcA>? M{n5dWlEPTBiPTC1MlMh|ryP MoXzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd6OUS1PFkoRjJ5OEm0OVg6RC:jPh?=
HeLa NWrMNYk5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MYi0PEBp MmHyS2k2OCB;IECuNFM5QSEQvF2= NUfzRnlLRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5OlQ5QDNpPkK3PVY1QDh|PD;hQi=>
MiaPaCa NGK1c4VIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MUe0PEBp MnWzS2k2OCB;IECuNFYh|ryP NXnYcVJTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5OlQ5QDNpPkK3PVY1QDh|PD;hQi=>
IMR32 NXrENYxQT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M1vDR|Q5KGh? NYPSb5IyT0l3MDC9JFAvODh4IN88US=> MoHLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd7NkS4PFMoRjJ5OU[0PFg{RC:jPh?=
MDA-MB-231 MXvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MUW0PEBp NGXnWIxIUTVyIE2gNE4xQTJizszN NUCyRXlSRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5OlQ5QDNpPkK3PVY1QDh|PD;hQi=>
DU145 NGe4XmpCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NGTuU5Q1QCCq MUXJR|UxKD1iMD6wNVEh|ryP NITlRYE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{m3PVU6Oyd-Mke5O|k2QTN:L3G+
HeLa M2rPNmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWi0PEBp Mo\jTWM2OCB;IECuNFM3KM7:TR?= NXLXU5dGRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5O|k2QTNpPkK3PVc6PTl|PD;hQi=>
MCF7 NVPLVnFRSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NUjpdmY{PDhiaB?= MmnOTWM2OCB;IECuOlMh|ryP NVfHZo83RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5O|k2QTNpPkK3PVc6PTl|PD;hQi=>
ECA109 M1PJdWFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWS0PEBp NYnoZZlqUUN3MDC9JFAvQTRizszN Mo\vQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjd7N{m1PVMoRjJ5OUe5OVk{RC:jPh?=
MDA-MB-435 M2TnSGN6fG:2b4jpZ4l1gSCjc4PhfS=> MlnJO|IhcA>? M1HNcmlEPTBiPTCwMlAxODJizszN NGHBWVk9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{N{m4N|g1Oid-Mke5PFM5PDJ:L3G+
HT-29 NULhRpVtS3m2b4TvfIlkcXS7IHHzd4F6 NYPUZ2hQPzJiaB?= MYDJR|UxKD1iMD6wNFA5KM7:TR?= MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzl6M{i0Nkc,Ojd7OEO4OFI9N2F-
MDA-MB-231 MmLBR5l1d3SxeHnjbZR6KGG|c3H5 MoCzO|IhcA>? MlXjTWM2OCB;IECuNFAzPyEQvF2= NVWwVHZqRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMke5PFM5PDJpPkK3PVg{QDR{PD;hQi=>
OVCAR3 NGj0SIREgXSxdH;4bYNqfHliYYPzZZk> MXm3NkBp M4r4NmlEPTBiPTCwMlAxOzNizszN MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzl6M{i0Nkc,Ojd7OEO4OFI9N2F-
H1299 MXLDfZRwfG:6aXPpeJkh[XO|YYm= MoLFNlQhcA>? MnXtTWM2OCB;IEGuOUDPxE1? MX28ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zPzl6M{i0Nkc,Ojd7OEO4OFI9N2F-
HEK-Blue MmW2SpVv[3Srb36gZZN{[Xl? MnzsN{Bp NF24fW9KSzVyIE2gO{46PDN{ODFOwG0> M1LCeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MEe1OVgyLz5{OEC3OVU5OTxxYU6=
A549 NWXze3pYSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NVvoV4ZMPzJiaB?= NXuwOGJGUUN3MDC9JFAvODB4MjFOwG0> MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDB7OUCwN{c,OjhyOUmwNFM9N2F-
KB NYjnT|dsSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NWi1Z2NqPzJiaB?= M3ezbWlEPTBiPTCwMlAxPjJ5IN88US=> MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDB7OUCwN{c,OjhyOUmwNFM9N2F-
MDA-MB-231 NVHGSVE2SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NV\JdVNNPzJiaB?= NWnPSXY6UUN3MDC9JFAvODB6OEKg{txO NYLPdnM1RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiwPVkxODNpPkK4NFk6ODB|PD;hQi=>
MCF7 NVfUNWs1SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M4HKdFczKGh? NV[xXYw3UUN3MDC9JFAvODFyNDFOwG0> M1n1e|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MEm5NFA{Lz5{OEC5PVAxOzxxYU6=
KBVIN MmXERY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MnvaO|IhcA>? Mn\4TWM2OCB;IEGuPVI3KM7:TR?= NXqyUIZIRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiwPVkxODNpPkK4NFk6ODB|PD;hQi=>
MDA-MB-435 NUO3V3RkSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= M3PDRmdKPTBiPTCwMlAxOSEQvF2= NV\mfGl{RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkixNVI2OTZpPkK4NVEzPTF4PD;hQi=>
A549 MljER5l1d3SxeHnjbZR6KGG|c3H5 MUS0PEBp Mn\ETWM2OCB;IE[uNVk2KM7:TR?= MX[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJ|N{[2Nkc,Ojh{M{e2OlI9N2F-
KB NX\IWHl2S3m2b4TvfIlkcXS7IHHzd4F6 NE\wW2Q1QCCq MWHJR|UxKD1iNj61PFch|ryP NYf6WFR[RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyN|c3PjJpPkK4NlM4PjZ{PD;hQi=>
MDA-MB-231 MV\DfZRwfG:6aXPpeJkh[XO|YYm= NHXkO4c1QCCq NH22fW5KSzVyIE2gPU4{QDRizszN NVHXNYVtRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyN|c3PjJpPkK4NlM4PjZ{PD;hQi=>
HeLa Mlz1R5l1d3SxeHnjbZR6KGG|c3H5 MlnTO|IhcA>? NUf5WItwUUN3MDC9JFAvODBzNDFOwG0> MknTQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh{NEC5NFkoRjJ6MkSwPVA6RC:jPh?=
MDA-MB-231 NFTOXGNEgXSxdH;4bYNqfHliYYPzZZk> MmjVO|IhcA>? NFrFW45KSzVyIE2gNE4xODJ4IN88US=> NED5Ooo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEK1Nlk3Oid-MkiyOVI6PjJ:L3G+
MDA-MB-435 MoTtR5l1d3SxeHnjbZR6KGG|c3H5 NUjERnhSPzJiaB?= NWjtXldQUUN3MDC9JFAvODB|MTFOwG0> M1XicVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6MkWyPVYzLz5{OEK1Nlk3OjxxYU6=
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MDA-MB-231 MkXiR5l1d3SxeHnjbZR6KGG|c3H5 NITmboc1QCCq M2\DdWlEPTBiPTCwMlA5KM7:TR?= NYPiSGprRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyOlI2OjZpPkK4NlYzPTJ4PD;hQi=>
HepG2 MYfDfZRwfG:6aXPpeJkh[XO|YYm= Ml;DTWM2OCB;IECuN{DPxE1? NFzEXms9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEK2NlUzPyd-MkiyOlI2Ojd:L3G+
Hep3B M4\6[mN6fG:2b4jpZ4l1gSCjc4PhfS=> MoPzTWM2OCB;IECuO|Mh|ryP MWm8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJ4MkWyO{c,Ojh{NkK1Nlc9N2F-
MRC5 NU\rOVl[S3m2b4TvfIlkcXS7IHHzd4F6 M33ObFczKGh? M4TI[mlEPTBiPTCwMlAxODV{IN88US=> NWTaNYdoRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyPFIyOjdpPkK4NlgzOTJ5PD;hQi=>
A549 NFfwRXRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{D6flczKGh? MWLJR|UxKD1iMD6wNFYzKM7:TR?= NX;0NmZTRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkiyPVA3QThpPkK4NlkxPjl6PD;hQi=>
KB MnziRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M1XkclczKGh? MnSxTWM2OCB;IECuNFA3OyEQvF2= MYq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJ7ME[5PEc,Ojh{OUC2PVg9N2F-
MDA-MB-231 MmqzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NInjV5o4OiCq MljuTWM2OCB;IECuNFA5QCEQvF2= MU[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJ7ME[5PEc,Ojh{OUC2PVg9N2F-
MCF7 NFTwZWVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NVPCV4ZXPzJiaB?= MnL0TWM2OCB;IECuNFExPCEQvF2= NFrKdWM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEK5NFY6QCd-MkiyPVA3QTh:L3G+
KBVIN M1viT2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M17Yb|czKGh? MkPCTWM2OCB;IEGuPVI3KM7:TR?= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDJ7ME[5PEc,Ojh{OUC2PVg9N2F-
PC3 NEXwdpdCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MWe3NkBp M1r1d2lEPTBiPTCwMlAxPCEQvF2= NImzVlE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEOzOVYxPid-MkizN|U3ODZ:L3G+
UACC62 NXf3dHBOSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NX7KeI1VPzJiaB?= MVPJR|UxKD1iMD6wNFYh|ryP NIf4d3I9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEOzOVYxPid-MkizN|U3ODZ:L3G+
M14 MXnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MYe3NkBp NFvsdpFKSzVyIE2gNE4xODdizszN NUDI[5ZwRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkizN|U3ODZpPkK4N|M2PjB4PD;hQi=>
SK-MEL-2 M{jD[GFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NFT6Vpo4OiCq M{PNTWlEPTBiPTCwMlAxQSEQvF2= NEfmb|E9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEOzOVYxPid-MkizN|U3ODZ:L3G+
NCI-H460 Mnr1RY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MVe3NkBp MmnrTWM2OCB;IECuNFEh|ryP NVzoOWZbRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkizN|U3ODZpPkK4N|M2PjB4PD;hQi=>
A375 NYTMcnJWSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= NUflZnptPzJiaB?= M3vhS2lEPTBiPTCwMlAyKM7:TR?= NGDQbo09[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEOzOVYxPid-MkizN|U3ODZ:L3G+
SF295 MoPHRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MXi3NkBp Mmr2TWM2OCB;IECuNFU3KM7:TR?= M{\kW|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{O1OlA3Lz5{OEOzOVYxPjxxYU6=
ACHN M3LqSmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 NW\ReG9UPzJiaB?= NVPhdmtvUUN3MDC9JFAvODZ4IN88US=> MlPzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh|M{W2NFYoRjJ6M{O1OlA3RC:jPh?=
HeLa NH;V[YFEgXSxdH;4bYNqfHliYYPzZZk> NUS0XIxwPDhiaB?= NVjrNJExUUN3MDC9JFAvODB6MkGg{txO MUi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDN2MESxNUc,Ojh|NEC0NVE9N2F-
A549 M3qxTGN6fG:2b4jpZ4l1gSCjc4PhfS=> MliyOFghcA>? NV;kUYV1UUN3MDC9JFAvODB7NUKg{txO NF24VWc9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEO0NFQyOSd-MkizOFA1OTF:L3G+
A549/TR MXLDfZRwfG:6aXPpeJkh[XO|YYm= MWW0PEBp M3zWNmlEPTBiPTCxMlUyKM7:TR?= Mn\iQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh|NEC0NVEoRjJ6M{SwOFEyRC:jPh?=
HeLa/TR NVm3SYlwS3m2b4TvfIlkcXS7IHHzd4F6 MlvWOFghcA>? NFOyWY9KSzVyIE2gNU42OyEQvF2= M37qblxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{SwOFEyLz5{OEO0NFQyOTxxYU6=
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A549 MVXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MVO3NkBp NG\uWm5KSzVyIE2gNE4xOjNizszN MYO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDN7NUG5PUc,Ojh|OUWxPVk9N2F-
HT-29 NGixTJFCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1HtTFczKGh? NF34S3hKSzVyIE2gNE4xOjVizszN Mki1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh|OUWxPVkoRjJ6M{m1NVk6RC:jPh?=
NCI-H596 NGL3W21CdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NEf0RYg4OiCq M4CzUWlEPTBiPTCwMlA{PSEQvF2= M1HIV|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6M{m1NVk6Lz5{OEO5OVE6QTxxYU6=
HT-29 NFyxWWlEgXSxdH;4bYNqfHliYYPzZZk> MU[zJIRigXN? Mon6TWM2OCB;IECuNFAyPCEQvF2= NV\FUVVkRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0NFk3OzdpPkK4OFA6PjN5PD;hQi=>
HeLa NWLMcmttSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MmrEOFghcA>? M{SxRmlEPTBiPTCwMlAxOTVizszN NHf2Z5c9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OESzN|UyOyd-Mki0N|M2OTN:L3G+
MDA-MB-435 MX3BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MlXOOFghcA>? MVXJR|UxKD1iMD6wNFIh|ryP M2r0e|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NEOzOVE{Lz5{OESzN|UyOzxxYU6=
SKOV3 NVzUPZFnSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MXO0PEBp NGi3VXVKSzVyIE2gNE4xODNizszN NHzsdJo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OESzN|UyOyd-Mki0N|M2OTN:L3G+
SKOV3-MDR1-M6/6 MW\BcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MV:0PEBp NE[zcWhKSzVyIE2gNk4{OyEQvF2= NXvOc4ZrRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki0N|M2OTNpPkK4OFM{PTF|PD;hQi=>
KB MXnBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MYTJR|UxKD1iMD6wNFU6KM7:TR?= MXW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDR3N{e1Okc,Ojh2NUe3OVY9N2F-
A549 M{PES2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MWPJR|UxKD1iMD6wNFY5PSEQvF2= MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDR3N{e1Okc,Ojh2NUe3OVY9N2F-
MDA-MB-231 NV3oWWtmSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MkC3TWM2OCB;IECuNFA6PjNizszN NEL3UmM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OES1O|c2Pid-Mki0OVc4PTZ:L3G+
MCF7 NFLtc|VCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NIPmXG1KSzVyIE2gNE4xOTF2NjFOwG0> NFTtO2U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OES1O|c2Pid-Mki0OVc4PTZ:L3G+
KBVIN NGrH[|hCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MnrmTWM2OCB;IEKuNFM2KM7:TR?= MorhQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2NUe3OVYoRjJ6NEW3O|U3RC:jPh?=
A2780 MXfBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NX71b|Y4OiCmYYnz NYD0OmV6UUN3MDC9JFAvODJ6IN88US=> Mor4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh2NkOwNFEoRjJ6NE[zNFAyRC:jPh?=
BGC823 NFzWVItEgXSxdH;4bYNqfHliYYPzZZk> Moe0PVYhcA>? MVnJR|UxKD1iMD6wNFA5KM7:TR?= NEHsW4Y9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEWzNFgzQCd-Mki1N|A5Ojh:L3G+
NCI-H460 MWTDfZRwfG:6aXPpeJkh[XO|YYm= NXPjZ3l{QTZiaB?= MWPJR|UxKD1iMD6wNFEh|ryP NXvDe4w5RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1N|A5OjhpPkK4OVMxQDJ6PD;hQi=>
HepG2 Mn75R5l1d3SxeHnjbZR6KGG|c3H5 NXT6VZc{QTZiaB?= NYTmNmN5UUN3MDC9JFAvODB4MzFOwG0> MlPIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3M{C4NlgoRjJ6NUOwPFI5RC:jPh?=
OVPF008 NWnOUGtvSW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MWm2JIRigXN? NGjHcolKSzVyIE2gNU4yKM7:TR?= NVrkdGFZRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1OFg5OjVpPkK4OVQ5QDJ3PD;hQi=>
OVPF038 NFW5VoVCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M1r3T|Yh\GG7cx?= NYHwU2ROUUN3MDC9JFEvPCEQvF2= MUC8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDV2OEiyOUc,Ojh3NEi4NlU9N2F-
KB MUPDfZRwfG:6aXPpeJkh[XO|YYm= NIjNSFQ4OiCq Ml\sTWM2OCB;IECuNFA{PiEQvF2= MkX6QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3OUCxNlQoRjJ6NUmwNVI1RC:jPh?=
KBv200 MXXDfZRwfG:6aXPpeJkh[XO|YYm= NV64[4JqPzJiaB?= MoD2TWM2OCB;IEKuNVE4KM7:TR?= MnflQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3OUCxNlQoRjJ6NUmwNVI1RC:jPh?=
MDA-MB-435 NXvEO|ZnS3m2b4TvfIlkcXS7IHHzd4F6 M2LuTFczKGh? NFvKcVhKSzVyIE2gNE4xODB3IN88US=> NYDSdZc4RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki1PVQyPjlpPkK4OVk1OTZ7PD;hQi=>
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MDA-MB-231 MV;DfZRwfG:6aXPpeJkh[XO|YYm= NX7VU3dLPzJiaB?= NUnrdWlFUUN3MDC9JFAvODB7IN88US=> Mm\RQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3OUSxOlkoRjJ6NUm0NVY6RC:jPh?=
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DU145 M4HCeGN6fG:2b4jpZ4l1gSCjc4PhfS=> MUO3NkBp MYrJR|UxKD1iMD6wNFI{KM7:TR?= MYK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDV7OE[zN{c,Ojh3OUi2N|M9N2F-
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HT-29 MkDQR5l1d3SxeHnjbZR6KGG|c3H5 Mo\3O|IhcA>? M4rzVWlEPTBiPTCwMlAxOyEQvF2= M1Th[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NUm4OlM{Lz5{OEW5PFY{OzxxYU6=
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MCF7 M{O2eGN6fG:2b4jpZ4l1gSCjc4PhfS=> NUH4R5ZLPzJiaB?= NUjTUVRrUUN3MDC9JFAvODB5MzFOwG0> MlHLQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh3OUi2N|MoRjJ6NUm4OlM{RC:jPh?=
A2780 MXHDfZRwfG:6aXPpeJkh[XO|YYm= MXG0PEBp MmnTTWM2OCB;IECuNFAyODdizszN NIrLSo49[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[yOFcxOyd-Mki2NlQ4ODN:L3G+
HeLa MYnDfZRwfG:6aXPpeJkh[XO|YYm= M2\EfFQ5KGh? NGfEToNKSzVyIE2gNE4xODFzIN88US=> NXe4OGl3RGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki2NlQ4ODNpPkK4OlI1PzB|PD;hQi=>
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Hela-beta3 NXjyOFQ1S3m2b4TvfIlkcXS7IHHzd4F6 MVW0PEBp M{i3N2lEPTBiPTCwMlAxQSEQvF2= M{TWd|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NkK0O|A{Lz5{OE[yOFcxOzxxYU6=
A2780AD NEiw[GpEgXSxdH;4bYNqfHliYYPzZZk> NVrWXlNuPDhiaB?= MnXmTWM2OCB;IEGuNlgzKM7:TR?= MY[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ{NEewN{c,Ojh4MkS3NFM9N2F-
KBV1 M1fqc2N6fG:2b4jpZ4l1gSCjc4PhfS=> MXq0PEBp Mn76TWM2OCB;IEmuPEDPxE1? MnLkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4MkS3NFMoRjJ6NkK0O|A{RC:jPh?=
BGC823 M3;CT2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M3;BbVMh\GG7cx?= M3rC[mlEPTBiPTCwMlAxOSEQvF2= NHHXemE9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[yOVM3Oyd-Mki2NlU{PjN:L3G+
HepG2 M3L2SGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MWGzJIRigXN? NV25TGRHUUN3MDC9JFAvODJizszN M1fFSFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NkK1N|Y{Lz5{OE[yOVM3OzxxYU6=
HCT116 NYn6cIZpT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MkjVN{Bl[Xm| MnvLTWM2OCB;IECuNFMh|ryP MkfRQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4MkWzOlMoRjJ6NkK1N|Y{RC:jPh?=
A2780 MoezS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGP0OY4{KGSjeYO= Mn3jTWM2OCB;IECuNFMh|ryP MWG8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ{NUO2N{c,Ojh4MkWzOlM9N2F-
NCI-H1650 MYPHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NHTnXXk{KGSjeYO= NHfvN3JKSzVyIE2gNE4xPyEQvF2= MmLNQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4MkWzOlMoRjJ6NkK1N|Y{RC:jPh?=
A2780 MUjBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MY[yJIRigXN? MXvJR|UxKD1iMD6wNVM4KM7:TR?= MWq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ2OES5NUc,Ojh4NEi0PVE9N2F-
KB MlTaR5l1d3SxeHnjbZR6KGG|c3H5 NHLMepI1QCCq NVjKPHl7T0l3MDC9JFAvODB3MUKg{txO MWW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ3M{i0Okc,Ojh4NUO4OFY9N2F-
A549 M1Lp[2N6fG:2b4jpZ4l1gSCjc4PhfS=> NH\adng1QCCq NILaeYhIUTVyIE2gNE4xODdyMzFOwG0> MYe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ3M{i0Okc,Ojh4NUO4OFY9N2F-
MDA-MB-231 NWO3WJBNS3m2b4TvfIlkcXS7IHHzd4F6 MWO0PEBp NYLqcGtLT0l3MDC9JFAvODFizszN M{nnWVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6NkWzPFQ3Lz5{OE[1N|g1PjxxYU6=
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MCF7 MlqxRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Mnr2OFghcA>? Ml\1TWM2OCB;IECuNFA5KM7:TR?= MnLzQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4NUSyOVYoRjJ6NkW0NlU3RC:jPh?=
HL60 NILQWGRCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MUW0PEBp MVLJR|UxKD1iMD6wNFgh|ryP Mo[wQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4NUSyOVYoRjJ6NkW0NlU3RC:jPh?=
SMMC7721 NEDZZ5ZCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= NUfnRXVKPDhiaB?= NUDOUFF1UUN3MDC9JFAvODB6IN88US=> NH;PVoU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[1OFI2Pid-Mki2OVQzPTZ:L3G+
A549 M3jkR2FvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M1;5fVQ5KGh? NXLWTJB7UUN3MDC9JFAvODB6IN88US=> NIPDfpo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[1OFI2Pid-Mki2OVQzPTZ:L3G+
SW480 MUPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NV3TOmdjPDhiaB?= MYTJR|UxKD1iMD6wNFgh|ryP NELxSpU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OE[1OFI2Pid-Mki2OVQzPTZ:L3G+
A375 MnPWRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NFzreno1QCCq MkWxTWM2OCB;IECuO{DPxE1? Mlr1QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh4Nke4O|IoRjJ6Nk[3PFczRC:jPh?=
MIAPaCa2 Mk[zRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? M3zoSlQ5KGh? MnfYTWM2OCB;IEKuOUDPxE1? MXi8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDZ4N{i3Nkc,Ojh4Nke4O|I9N2F-
HEY M4PJemN6fG:2b4jpZ4l1gSCjc4PhfS=> M12yeFQ5KGh? NEm5N2pKSzVyIE2gNE4yODRzIN88US=> MVe8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDdzOUKwOEc,Ojh5MUmyNFQ9N2F-
A2780 NFLjS29EgXSxdH;4bYNqfHliYYPzZZk> MX60PEBp MnLkTWM2OCB;IECuNVY1OiEQvF2= MYW8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDdzOUKwOEc,Ojh5MUmyNFQ9N2F-
HCT116 NYDPbVg5T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NYDqRm1IQTZiaB?= MmfrTWM2OCB;IECuNFAxOiEQvF2= NHLZUJM9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEezO|M6Pid-Mki3N|c{QTZ:L3G+
BGC823 M4rMUGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M1rrfFk3KGh? NEjvTXRKSzVyIE2gNE4xODB4IN88US=> Ml;EQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5M{ezPVYoRjJ6N{O3N|k3RC:jPh?=
HepG2 MXnHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NEHLeG46PiCq MV;JR|UxKD1iMD6wNFc3KM7:TR?= M2TRTFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{O3N|k3Lz5{OEezO|M6PjxxYU6=
A2780 MnTPS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MljYPVYhcA>? NHqwcZFKSzVyIE2gNE4xOjB2IN88US=> M2j6SlxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzJ6N{O3N|k3Lz5{OEezO|M6PjxxYU6=
A549 NHrBUZpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MlzlOEBl[Xm| MXjHTVUxKD1iMD6wNFM4KM7:TR?= MnXIQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NEC2NFEoRjJ6N{SwOlAyRC:jPh?=
PC3 Ml;iS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXj6T3prPCCmYYnz MUnHTVUxKD1iMD6wNFU5KM7:TR?= NYr1U4tmRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OFA3ODFpPkK4O|QxPjBzPD;hQi=>
NCI-H460 MmnGR5l1d3SxeHnjbZR6KGG|c3H5 M3HvWlczKGh? MmnnTWM2OCB;IECuNFA3KM7:TR?= NWX0VZhvRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OFA3OTNpPkK4O|QxPjF|PD;hQi=>
HT-29 NIfucVNEgXSxdH;4bYNqfHliYYPzZZk> NGDXUmU4OiCq MnHoTWM2OCB;IECuNFE1KM7:TR?= MXS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd2ME[xN{c,Ojh5NEC2NVM9N2F-
A2780S MljvRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? MnP2OFghcA>? MYTJR|UxKD1iMD6wNVI{KM7:TR?= NVXHXJhKRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki3OlM3PDZpPkK4O|Y{PjR4PD;hQi=>
HCT8 NH\BOHlCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MofNOFghcA>? MlznTWM2OCB;IECuNFE4PCEQvF2= MVK8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8zQDd4M{[0Okc,Ojh5NkO2OFY9N2F-
HCT8/T M3PhWGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 MmXTOFghcA>? MYLJR|UxKD1iOT64PFUh|ryP MmTkQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjh5NkO2OFYoRjJ6N{[zOlQ3RC:jPh?=
A549 NYTqcYR7S3m2b4TvfIlkcXS7IHHzd4F6 MojsNlQhcA>? MX\JR|UxKD1iMD6wNFQyKM7:TR?= NFHkTo89[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEizOVc6PCd-Mki4N|U4QTR:L3G+
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PA1 MXTBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? NGi2XnY4OiCq NYnxcXA1UUN3MDC9JFAvODB|IN88US=> NITEZmU9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OEi1O|U2QCd-Mki4OVc2PTh:L3G+
HCT116 NF7uR5VCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MnfuO|IhcA>? NFPBcYhKSzVyIE2gNE4xODRzIN88US=> NXqz[nUyRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMki4OVc2PThpPkK4PFU4PTV6PD;hQi=>
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HCT116 Mk\iS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mk\iO|IhcA>? MU\JR|UxKD1iMD6wNFQyKM7:TR?= NFzVWVQ9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUSzPVg6QSd-Mkm0N|k5QTl:L3G+
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paclitaxel-resistant MCF7 MnLKR5l1d3SxeHnjbZR6KGG|c3H5 MYm3NkBp M1\pe2lEPTBiPTCyMlI6ODh5IN88US=> NUDidY5mRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm0Olg5PzJpPkK5OFY5QDd{PD;hQi=>
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A549 NEK4ZZBCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{D6R|czKGh? NV3ufWxvUUN3MDC9JFAvODB5IN88US=> NHH4Xmg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9{OUWwNVk1Pyd-Mkm1NFE6PDd:L3G+
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A2780cis NFT2NVBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MV[3NkBp NXvsSpR2UUN3MDC9JFAvODB|IN88US=> MkTBQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOjl3MUm3N|coRjJ7NUG5O|M4RC:jPh?=
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ovarian epithelial MnHDS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MoHDOFghcA>? NH\iXJdKSzVyIE2gNE4xOyEQvF2= NWq3bGJDRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm1NVk4OzdpPkK5OVE6PzN5PD;hQi=>
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HL-60(TB) MkT6S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NF\yXo41QCCq M{HhbmdKPTBiPTCwMlAxPCEQvF2= NYTBV2loRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxMkm2OVU3OTBpPkK5OlU2PjFyPD;hQi=>
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MDA-MB-231 NV\6U5lXS3m2b4TvfIlkcXS7IHHzd4F6 NXTsXmtsPzJiaB?= NUTuVoxYUUN3MDC9JFAvODB{NjFOwG0> M2XNeVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyMUmyOVM4Lz5|MEG5NlU{PzxxYU6=
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OVCAR3 MlX0R5l1d3SxeHnjbZR6KGG|c3H5 M4Kx[|czKGh? M2OxTWlEPTBiPTCwMlAxPzVizszN Mkm4QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzBzOUK1N|coRjNyMUmyOVM4RC:jPh?=
MV411 MUPBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MW[3NkBp M3excWlEPTBiPTCwMlAyPyEQvF2= MoL2QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB{MUKxPVgoRjNyMkGyNVk5RC:jPh?=
HGC27 M3rFbGFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M{DNO|czKGh? NXTtNodFUUN3MDC9JFAvODJ6IN88US=> NH;X[3U9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEKxNlE6QCd-M{CyNVIyQTh:L3G+
HeLa NVHaWI1{SW62aYDyc4xq\mW{YYTpeoUh[WO2aY\peJkh[XO|YYm= MlzRO|IhcA>? NG\rZXNKSzVyIE2gNE4xPDZizszN MkHOQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB{MUKxPVgoRjNyMkGyNVk5RC:jPh?=
A549 MlXzRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? Mkn6O|IhcA>? MY\JR|UxKD1iMD6wOVEh|ryP Mlf3QIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB{MUKxPVgoRjNyMkGyNVk5RC:jPh?=
HeLa MojQRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NHHieJA1QCCq MmDGTWM2OCB;IECuNFAzQCEQvF2= MUO8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODJ7N{GxPEc,OzB{OUexNVg9N2F-
SKOV3 NF76c|RCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= Mki2OFghcA>? MY\JR|UxKD1iMD6wNFUh|ryP MWS8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODJ7N{GxPEc,OzB{OUexNVg9N2F-
SKOV3-MDR1-M6/6 NHvZTJNCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MlnJOFghcA>? M1jYSGlEPTBiPTCxMlIh|ryP MXy8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODJ7N{GxPEc,OzB{OUexNVg9N2F-
HCC1806 M4T0SmFvfGmycn;sbYZmemG2aY\lJIFkfGm4aYT5JIF{e2G7 M1H6WlI1KGh? NX;XSHFWUUN3MDC9JFAvODBzIN88US=> NIq4RXg9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEO5Nlk2Oyd-M{CzPVI6PTN:L3G+
BEAS2B MVXBcpRqeHKxbHnm[ZJifGm4ZTDhZ5Rqfmm2eTDhd5NigQ>? MW[yOEBp M3jufWlEPTBiPTCwMlAxPyEQvF2= NFvuOJo9[SC2YYLn[ZQ:L1:kbHHub{chcHKnZk2nbJR1eHN8Lz;weYJu\WRwbnPibU5vdG1wbnnoModwfi9|MEO5Nlk2Oyd-M{CzPVI6PTN:L3G+
HT-29 NEi2WYtCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= M{LMUlI1KGh? NIDkcIdKSzVyIE2gNE4xODhizszN MV68ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODN7Mkm1N{c,OzB|OUK5OVM9N2F-
HepG2 NFTyOplCdnSrcILvcIln\XKjdHn2[UBi[3Srdnn0fUBie3OjeR?= MW[yOEBp NEnPOY1KSzVyIE2gNE4xODlizszN M2LFUVxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyM{myPVU{Lz5|MEO5Nlk2OzxxYU6=
PANC1 MnzDRY51cXC{b3zp[oVz[XSrdnWgZYN1cX[rdImgZZN{[Xl? NHrSTZEzPCCq NFW4NpVKSzVyIE2gNE4xPCEQvF2= M4rWeFxiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyM{myPVU{Lz5|MEO5Nlk2OzxxYU6=
MDA-MB-231 MUfDfZRwfG:6aXPpeJkh[XO|YYm= MX[0PEBp Mn;nTWM2OCB;IECuNFA1KM7:TR?= NWjiS|hJRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C0N|M4QDNpPkOwOFM{Pzh|PD;hQi=>
A549 NHXvW|dEgXSxdH;4bYNqfHliYYPzZZk> MXO0PEBp M1X0XGlEPTBiPTCwMlAxPCEQvF2= MmHyQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB2M{O3PFMoRjNyNEOzO|g{RC:jPh?=
PANC1 MoPqR5l1d3SxeHnjbZR6KGG|c3H5 MlnqOFghcA>? NFXaRnVKSzVyIE2gNE4xPiEQvF2= MVq8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODR|M{e4N{c,OzB2M{O3PFM9N2F-
4T1 MYfDfZRwfG:6aXPpeJkh[XO|YYm= MVq0PEBp NEiwcppKSzVyIE2gNE4xQTRizszN Ml;yQIEhfGG{Z3X0QUdg[myjbnunJIhz\WZ;J3j0eJB{Qi9xcIXicYVlNm6lYnmucoxuNm6raD7nc5YwOzB2M{O3PFMoRjNyNEOzO|g{RC:jPh?=
A375 NYDGb25{S3m2b4TvfIlkcXS7IHHzd4F6 NH2zOVY1QCCq M1nmS2lEPTBiPTCwMlEh|ryP M1HI[|xiKHSjcnfleF0oZ2KuYX7rK{BpemWoPTfoeJRxezpxL4D1Zo1m\C6wY3LpMo5tdS6waXiu[493NzNyNEOzO|g{Lz5|MESzN|c5OzxxYU6=
LLC M2TqNGN6fG:2b4jpZ4l1gSCjc4PhfS=> NVTO[ZViPDhiaB?= M4DKUGlEPTBiPTCwMlE5QSEQvF2= MVu8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODR|M{e4N{c,OzB2M{O3PFM9N2F-
B16F10 NX7FTHNkS3m2b4TvfIlkcXS7IHHzd4F6 NFXzO4E1QCCq Mm\aTWM2OCB;IECuOVMh|ryP MV[8ZUB1[XKpZYS9K39jdGGwazegbJJm\j1paIT0dJM7Ny:ydXLt[YQvdmOkaT7ucI0vdmmqLnfvek8{ODR|M{e4N{c,OzB2M{O3PFM9N2F-
B16F10 spheroid M4HVNWN6fG:2b4jpZ4l1gSCjc4PhfS=> M{PBb|Q5KGh? MmLNTWM2OCB;IEiuNFEh|ryP NXPaO3ZHRGFidHHy[4V1RSehYnzhcosoKGi{ZX[9K4h1fHC|Oj:vdJVjdWWmLn7jZokvdmyvLn7pbE5od3ZxM{C0N|M4QDNpPkOwOFM{Pzh|PD;hQi=>

... Click to View More Cell Line Experimental Data

Assay
Methods Test Index PMID
Western blot
p-ERK / ERK; 

PubMed: 20068074     


Paclitaxel pulse induces phospho-ERK. Paclitaxel (6ug/mL) was pulsed over 10min to 4hr prior to cell harvesting. A biphasic activation is observed in the resistant cells.

MARCKS (pSer159/163); 

PubMed: 26015406     


Paclitaxel treatment induces activation of MARCKS and Src in TNBC cells. Cells were incubated with various doses of paclitaxel as indicated. After 24 hours, cells were collected and subjected to Western blot analysis.

Src (pTyr416); 

PubMed: 26015406     


Paclitaxel treatment induces activation of MARCKS and Src in TNBC cells. Cells were incubated with various doses of paclitaxel as indicated. After 24 hours, cells were collected and subjected to Western blot analysis.

p-JAK2 / p-STAT3 / p-AKT / p-MAPK / Bcl-xl / MCL-1; 

PubMed: 29849942     


OVCAR-8 and MDAH2774 cells were treated with ruxolitinib (20 μM), paclitaxel (10 nM) or the combination for 24 h. Whole cells were collected and determined for the change of STAT3, AKT and ERK pathways and expression of BCL-XL and MCL-1 by Western blot.

Id1; 

PubMed: 25344919     


(A) Paclitaxel suppressed Id1 expression in H520 cells in a time-dependent manner.

MARCKS; 

PubMed: 26015406     


Paclitaxel treatment induces activation of MARCKS and Src in TNBC cells. Cells were incubated with various doses of paclitaxel as indicated. After 24 hours, cells were collected and subjected to Western blot analysis.

20068074 26015406 29849942 25344919
Growth inhibition assay
Cell viability; 

PubMed: 28823711     


Paclitaxel reduces HeyA8 tumor cell viability in MTT assay.

28823711
Immunofluorescence
α-tubulin; 

PubMed: 22904633     


Cellular α-tubulin (red) was blotted by immunostaining and subsequent confocal microscopy 3 hours after A549 cells were treated with 12.5 nM of paclitaxel and 12.5 nM of PLGA-PEI-TAX, respectively. The same experiment was performed with 62.5 nM of paclitaxel and 62.5 nM of PLGA-PEI-TAX in A549/T12 cells. PLGA-PEI-TAX, poly(lactic-co-glycolic acid)-polyethylenimine nanoparticles loaded with paclitaxel.

Rab11a/BV9; 

PubMed: 29290815     


Paclitaxel reversed the DAVLBH-mediated inhibition of internalized VE-cadherin recycling back to the cell membrane. HUVECs pretreated with or without paclitaxel were treated with or without DAVLBH for 4 h. Quantification of BV9/Rab11a colocalization is shown (n = 3).

22904633 29290815
In vivo

The inhibition rations of Paclitaxel alone on BC-V and BC-ER tumors are 49.78% and 51.23%, respectively. Treatment of six cycles of 20 mg/kg Paclitaxel significantly reduces the percentages of Ki-67-positive cells to 20.4% in BC-V tumors and 25.1% in BC-ER tumors, respectively. [4]

Protocol

Cell Research:

[1]

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  • Cell lines: Cells including human neonatal dermal microvascular ECs (HMVECs), human umbilical vein ECs (HUVECs), human umbilical artery ECs (HUAVECs), normal human astrocytes (NHAs), normal human dermal fibroblasts (NHDFs), normal human epidermal keratinocytes (NHEKs
  • Concentrations: 0.1-100 pM
  • Incubation Time: 72 hours
  • Method:

    Cells including human neonatal dermal microvascular ECs (HMVECs), human umbilical vein ECs (HUVECs), human umbilical artery ECs (HUAVECs), normal human astrocytes (NHAs), normal human dermal fibroblasts (NHDFs), normal human epidermal keratinocytes (NHEKs), human mammary epithelial cells (HMEpCs), human prostate epithelial cells (PrEpCs) and human umbilical artery smooth muscle cells (UASMCs) are cultured. Cell proliferations are performed in 96-well plates using cells between passages 6 and 12. Cells are seeded at 3000–5000 cells/well and allowed to attach for 4 hours. Paclitaxel, diluted in culture medium, is added in quadruplicate wells and the cells ae incubated for 3 days before MTS reagents are added to quantitate the live cells in each well.


    (Only for Reference)
Animal Research:

[4]

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  • Animal Models: Female, 20-22 g homozygous nude athymic mice with BC-V and BC-ER tumors
  • Dosages: 20 mg/kg
  • Administration: Administered via i.v.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 171 mg/mL (200.25 mM)
Water Insoluble
Ethanol ''18 mg/mL
In vivo Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):
5% DMSO+40% PEG 300+5% Tween 80+ddH2O
For best results, use promptly after mixing.
6mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 853.91
Formula

C47H51NO14

CAS No. 33069-62-4
Storage powder
in solvent
Synonyms PTX, Taxol, Onxal, Abraxane
Smiles CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
CalculateReset

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04252768 Not yet recruiting Drug: Eftilagimod Alpha|Drug: Paclitaxel Metastatic Breast Cancer Immutep S.A.S. June 2022 Phase 1
NCT04675450 Not yet recruiting Drug: Placebo|Drug: NBP Softgel Capsules Breast Cancer|Peripheral Neuropathy Conjupro Biotherapeutics Inc.|CSPC-NBP Pharmaceutical Co. Ltd. June 30 2022 Phase 2
NCT04715542 Not yet recruiting Drug: Stibium metallicum praeparatum 6x|Drug: Placebo Chemotherapy Induced Peripheral Neuropathy (CIPN) University of Bern|University Hospital Inselspital Berne|Hospital of Thun January 2022 Phase 3
NCT04809844 Not yet recruiting Other: Concurrent chemoradiation Breast Cancer Assiut University December 2021 --
NCT04831320 Not yet recruiting Drug: nab-paclitaxel|Drug: Nivolumab Metastatic Head-and-neck Squamous-cell Carcinoma Washington University School of Medicine|Bristol-Myers Squibb September 30 2021 Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

Frequently Asked Questions

  • Question 1:

    I am interested in the product S1150 for in vivo studies, could you please give some suggestions for the formulation?

  • Answer:

    S1150 in 1% DMSO+30% polyethylene glycol+1% Tween 80 at 30mg/ml is a suspension. If the you want to inject it, there is another vehicle, 5% DMSO+5% Tween 80+ddH2O. S1150 can dissolve in it at 2.5mg/ml as a clear solution. It is a common formulation we used, but is not cited from reference.

  • Question 2:

    the compound was dissolved into 1ml DMSO and diluted with 1x PBS or water (500ul + 9.5 ml PBS or water). I found the white precipitation goes out. How to figure it out?

  • Answer:

    Paclitaxel has very low solubility in water based solution and that's why it precipitated out once you dilute the stock with water. The vehicle we suggest is: 1% DMSO+30% polyethylene glycol+1% Tween 80.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID