Numerous clinical trials evaluate the therapeutic efficacy and safety of paclitaxel across early- to late-phase investigations. These studies address conditions such as breast cancer, esophageal squamous cell carcinoma, recurrent high-grade uterine cancer, pancreatic cancer, chemotherapy-induced peripheral neuropathy, and coronary artery disease. Sponsored by academic medical centers, government institutes like the National Cancer Institute, and corporate entities such as Servier and Biotronik AG, their recruitment statuses include actively recruiting, completed, not yet recruiting, and withdrawn.
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT07528768 | NOT_YET_RECRUITING | Triple Negative Breast Cancer; Metastatic Triple-negative Breast Cancer |
AntiCancer Research Jamaica |
2026-06-01 | PHASE2 |
| NCT04198766 | RECRUITING | Solid Tumor; Non-Small Cell Lung Cancer; Head and Neck Cancer; Melanoma; Gastric Cancer; Renal Cell Carcinoma; Urothelial Carcinoma; Resectable Non-Small-Cell Lung Cancer |
Inhibrx Biosciences, Inc |
2019-12-10 | PHASE1; PHASE2 |
| NCT06714604 | RECRUITING | Locally Advanced Pancreatic Adenocarcinoma; Borderline Resectable Pancreatic Carcinoma; Pancreas Cancer; Neoadjuvant Chemotherapy; Surgery; Pancreatectomy |
Sahlgrenska University Hospital |
2023-10-18 | PHASE3 |
| NCT07629817 | RECRUITING | Esophageal Squamous Cell Carcinoma |
Henan Cancer Hospital |
2026-06-16 | PHASE3 |
| NCT07346196 | NOT_YET_RECRUITING | Squamous Cell Carcinoma |
University of Chicago |
2027-02-07 | PHASE2 |
| NCT05919537 | ACTIVE_NOT_RECRUITING | Non-Small Cell Lung Cancer; Pancreatic Cancer; Locally Advanced Solid Tumor; Metastatic Solid Tumor |
Hummingbird Bioscience |
2023-09-06 | PHASE1 |
| NCT01042379 | RECRUITING | Breast Neoplasms; Breast Cancer; Breast Tumors; Angiosarcoma; TNBC - Triple-Negative Breast Cancer; HER2-positive Breast Cancer; HER2-negative Breast Cancer; Hormone Receptor Positive Tumor; Hormone Receptor Negative Tumor; Early-stage Breast Cancer; Locally Advanced Breast Cancer |
QuantumLeap Healthcare Collaborative |
2010-03-01 | PHASE2 |
| NCT07001618 | RECRUITING | NSCLC (Advanced Non-small Cell Lung Cancer) |
Gustave Roussy, Cancer Campus, Grand Paris |
2025-11-17 | PHASE2 |
| NCT07155629 | NOT_YET_RECRUITING | Pancreatic Cancer Resectable |
Helsinki University Central Hospital |
2025-09-01 | PHASE3 |
| NCT05983276 | RECRUITING | Ovarian Cancer |
Loyola University |
2023-11-16 | PHASE2 |
| NCT07739199 | NOT_YET_RECRUITING | Squamous Non-small-cell Lung Cancer |
Sichuan Baili Pharmaceutical Co., Ltd. |
2026-08 | PHASE2; PHASE3 |
| NCT06647563 | NOT_YET_RECRUITING | Squamous Cell Carcinoma of Head and Neck |
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University |
2024-11-01 | PHASE3 |
| NCT05905315 | RECRUITING | Locally Advanced Vulvar Carcinoma; Squamous Cell Carcinoma of the Vulva |
The Netherlands Cancer Institute |
2024-01-01 | PHASE2 |
| NCT07683221 | NOT_YET_RECRUITING | Pancreatic Cancer |
Shandong Cancer Hospital and Institute |
2026-07-15 | PHASE2 |
| NCT06953323 | RECRUITING | Advanced Solid Tumor |
Wigen Biomedicine Technology (Shanghai) Co., Ltd. |
2025-07-10 | PHASE1; PHASE2 |
| NCT06486441 | ACTIVE_NOT_RECRUITING | Endometrial Cancer |
Gilead Sciences |
2024-08-28 | PHASE3 |
| NCT06245889 | RECRUITING | Triple Negative Breast Cancer |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2024-05-01 | PHASE2 |
| NCT07076121 | ACTIVE_NOT_RECRUITING | Pancreatic Ductal Adenocarcinoma |
Bristol-Myers Squibb |
2025-10-23 | PHASE2; PHASE3 |
| NCT06771154 | NOT_YET_RECRUITING | Recurrent/Metastatic Endometrial Cancer |
Peking Union Medical College Hospital |
2025-04-01 | PHASE2 |
| NCT07463313 | NOT_YET_RECRUITING | Thymoma and Thymic Carcinoma |
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine |
2026-03 | PHASE2; PHASE3 |
| NCT06996782 | RECRUITING | Advanced or Metastatic Non-small Cell Lung Cancer |
AstraZeneca |
2025-11-24 | PHASE1; PHASE2 |
| NCT07610525 | NOT_YET_RECRUITING | Triple Negative Breast Cancer; Blood and Image Guided; Optimization of Neoadjuvant Therapy; Phase 2 |
M.D. Anderson Cancer Center |
2026-11-05 | PHASE2 |
| NCT06712316 | RECRUITING | Non-small Cell Lung Cancer |
BioNTech SE |
2025-01-07 | PHASE2; PHASE3 |
| NCT07622797 | RECRUITING | Late-stage Resectable Esophageal Squamous Carcinoma |
The First Affiliated Hospital of Henan University of Science and Technology |
2025-11-21 | PHASE2 |
| NCT07277452 | NOT_YET_RECRUITING | Pancreatic Cancer, Adult |
The First Affiliated Hospital with Nanjing Medical University |
2025-12-10 | PHASE2 |
| NCT07226856 | RECRUITING | Metastatic Pancreatic Adenocarcinoma; Recurrent Pancreatic Adenocarcinoma; Stage IV Pancreatic Cancer AJCC v8 |
Mayo Clinic |
2025-12-12 | PHASE2 |
| NCT06535607 | RECRUITING | Sub-study 1 Cervical Cancer (Volrustomig Monotherapy); Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy); Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy); Sub-study 4 Esophageal Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy); Sub-study 5 Unresectable Pleural Mesothelioma (Volrustomig Monotherapy) |
AstraZeneca |
2024-08-22 | PHASE2 |
| NCT07213804 | RECRUITING | Ovarian Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Neoplasm Metastasis |
Eli Lilly and Company |
2025-10-22 | PHASE3 |
| NCT06904378 | RECRUITING | Metastatic Pancreatic Ductal Adenocarcinoma |
Washington University School of Medicine |
2026-03-25 | PHASE1; PHASE2 |
| NCT07784413 | NOT_YET_RECRUITING | Gastric Cancer Peritoneal Metastasis (GCPM) |
Zhejiang Cancer Hospital |
2026-09-01 | PHASE2 |
| NCT07016399 | RECRUITING | Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma |
Vandana Abramson |
2025-09-09 | PHASE2 |
| NCT06561763 | NOT_YET_RECRUITING | High Risk Locally Advanced Nasopharyngeal Carcinoma |
Sun Yat-sen University |
2024-08-20 | PHASE3 |
| NCT04715542 | NOT_YET_RECRUITING | Chemotherapy Induced Peripheral Neuropathy (CIPN) |
University of Bern |
2026-08 | PHASE3 |
| NCT06204614 | ENROLLING_BY_INVITATION | Muscle Invasive Bladder Urothelial Carcinoma |
Brigham and Women's Hospital |
2024-06-14 | EARLY_PHASE1 |
| NCT07445295 | NOT_YET_RECRUITING | Metastatic Pancreatic Ductal Adenocarcinoma |
Chipscreen Biosciences, Ltd. |
2026-03-31 | PHASE3 |
| NCT04241276 | ACTIVE_NOT_RECRUITING | Pancreatic Cancer |
Queen Mary University of London |
2020-04-30 | PHASE2 |
| NCT04811703 | RECRUITING | Metastatic Ovarian Carcinoma; Peritoneal Carcinomatosis; Stage III Ovarian Cancer; Stage IV Ovarian Cancer; Stage III Fallopian Tube Cancer; Stage IV Fallopian Tube Cancer; Metastatic Malignant Neoplasm in the Peritoneum |
Hospices Civils de Lyon |
2021-07-30 | PHASE1 |
| NCT05502237 | ACTIVE_NOT_RECRUITING | Non-small Cell Lung Cancer |
Gilead Sciences |
2022-10-12 | PHASE3 |
| NCT05365581 | RECRUITING | Gastric Adenocarcinoma; Gastroesophageal Junction (GEJ) Adenocarcinoma; Pancreatic Adenocarcinoma |
Astellas Pharma Global Development, Inc. |
2022-06-07 | PHASE1 |
| NCT07796126 | NOT_YET_RECRUITING | Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) |
Barbara Ann Karmanos Cancer Institute |
2026-09-30 | PHASE2 |
| NCT06835400 | NOT_YET_RECRUITING | Metastatic Breast Cancer |
Health Hope Pharma |
2025-09 | PHASE3 |
| NCT07465757 | NOT_YET_RECRUITING | Small Cell Lung Cancer ( SCLC ) |
Puma Biotechnology, Inc. |
2026-09-30 | PHASE2 |
| NCT07290140 | RECRUITING | Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps |
Airiver Medical, Inc. |
2026-06-01 | |
| NCT07045311 | RECRUITING | Triple-negative Breast Cancer |
Shanghai Junshi Bioscience Co., Ltd. |
2025-09-17 | PHASE2 |
| NCT05751668 | SUSPENDED | Anatomic Stage IV Breast Cancer AJCC v8; Chemotherapy-Induced Peripheral Neuropathy; Metastatic Breast Carcinoma |
Alliance for Clinical Trials in Oncology |
2023-11-02 | PHASE2 |
| NCT05684276 | ACTIVE_NOT_RECRUITING | NSCLC; Pancoast Tumor |
Fundación GECP |
2023-05-12 | PHASE2 |
| NCT04931342 | ACTIVE_NOT_RECRUITING | Ovarian Cancer |
Hoffmann-La Roche |
2021-10-07 | PHASE2 |
| NCT06771622 | ACTIVE_NOT_RECRUITING | Solid Cancer |
FBD Biologics Limited |
2025-03-13 | PHASE1; PHASE2 |
| NCT02726997 | ACTIVE_NOT_RECRUITING | Stage III Fallopian Tube Cancer AJCC v7; Stage III Ovarian Cancer AJCC v6 and v7; Stage III Primary Peritoneal Cancer AJCC v7; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7 |
M.D. Anderson Cancer Center |
2016-07-06 | PHASE1; PHASE2 |
| NCT07477743 | RECRUITING | Advanced Solid Tumor Cancer |
HC Biopharma Inc. |
2026-03-17 | PHASE1 |
| NCT07401654 | NOT_YET_RECRUITING | Ovarian Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2026-01-31 | PHASE2 |
| NCT07244978 | NOT_YET_RECRUITING | Esophageal Squamous Cell Carcinoma; Neoadjuvant Therapy |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2026-06-01 | PHASE2 |
| NCT06692491 | NOT_YET_RECRUITING | Rare Tumour |
Peking University Shenzhen Hospital |
2025-01-01 | PHASE2 |
| NCT06711094 | NOT_YET_RECRUITING | HR+/HER2- Advanced Breast Cancer |
Fujian Medical University |
2025-01-01 | |
| NCT06764355 | RECRUITING | ESCC; Total Neoadjuvant Treatment; Pathological Complete Response |
National Taiwan University Hospital |
2025-07-23 | PHASE2 |
| NCT07481058 | RECRUITING | Esophageal Squamous Cell Carcinoma (ESCC) |
Beijing Konruns Pharmaceutical Co., Ltd. |
2025-12-12 | PHASE2 |
| NCT07392346 | RECRUITING | Gastric Cancer Adenocarcinoma Metastatic |
Dai, Guanghai |
2025-12-01 | PHASE2 |
| NCT05256225 | RECRUITING | Endometrial Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Dedifferentiated Carcinoma; Endometrial Endometrioid Adenocarcinoma; Endometrial Mixed Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Undifferentiated Carcinoma; Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor |
National Cancer Institute (NCI) |
2022-11-16 | PHASE3 |
| NCT05296798 | ACTIVE_NOT_RECRUITING | Locally Advanced or Metastatic Breast Cancer |
Hoffmann-La Roche |
2022-07-18 | PHASE3 |
| NCT05487391 | RECRUITING | Carcinoma, Non-Small-Cell Lung |
Qilu Pharmaceutical Co., Ltd. |
2022-12-08 | PHASE3 |
| NCT06483555 | RECRUITING | Pancreatic Adenocarcinoma; Metastatic Pancreatic Cancer; Basal Cell Neoplasm |
UNC Lineberger Comprehensive Cancer Center |
2025-02-06 | PHASE1; PHASE2 |
| NCT06962267 | RECRUITING | Pancreatic Cancer |
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. |
2025-04-18 | PHASE2 |
| NCT07739485 | RECRUITING | Triple -Negative Breast Cancer |
Liu Shu |
2026-07-30 | PHASE1; PHASE2 |
| NCT07662746 | RECRUITING | Head and Neck Cancer |
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University |
2026-07-01 | PHASE2 |
| NCT06752811 | RECRUITING | Pancreatic Cancer Metastatic |
Shanghai Yizhong Pharmaceutical Co., Ltd. |
2025-02-05 | PHASE3 |
| NCT06942234 | RECRUITING | Inoperable Locally Advanced HER2-Negative Breast Cancer; Metastatic HER2-Negative Breast Cancer |
Jiangsu Alphamab Biopharmaceuticals Co., Ltd |
2025-06-01 | PHASE1; PHASE2 |
| NCT05420454 | RECRUITING | Breast Cancer |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2022-07-10 | PHASE4 |
| NCT06415318 | RECRUITING | Penile Cancer |
Sun Yat-sen University |
2024-05-31 | PHASE2 |
| NCT07669740 | NOT_YET_RECRUITING | Gastric Cancer (Diagnosis) |
The First Affiliated Hospital with Nanjing Medical University |
2026-07-01 | PHASE2 |
| NCT02297217 | RECRUITING | Esophageal Cancer |
AHS Cancer Control Alberta |
2019-11-21 | PHASE2 |
| NCT06407310 | NOT_YET_RECRUITING | Triple Negative Breast Cancer |
Tel Aviv Medical Center |
2024-07-01 | PHASE2 |
| NCT06494514 | RECRUITING | Locally Advanced Pancreatic Cancer |
Du Juan |
2024-04-01 | |
| NCT07549958 | RECRUITING | Pancreatic Cancer; Pancreatic Cancer Metastatic |
University of California, Irvine |
2026-03-24 | PHASE1 |
| NCT04158635 | SUSPENDED | Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Carcinoma |
City of Hope Medical Center |
2021-09-01 | PHASE1 |
| NCT06727565 | ACTIVE_NOT_RECRUITING | Head and Neck Squamous Cell Carcinoma |
Gilead Sciences |
2025-02-18 | PHASE2 |
| NCT05497778 | ACTIVE_NOT_RECRUITING | Pancreas Cancer |
M.D. Anderson Cancer Center |
2022-10-21 | PHASE1 |
| NCT06770452 | RECRUITING | Metastatic Pancreatic Carcinoma |
Zhejiang University |
2025-03-25 | PHASE2 |
| NCT05325632 | RECRUITING | HER2-positive Breast Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2021-10-28 | PHASE2 |
| NCT05969171 | RECRUITING | Pancreatic Cancer Metastatic |
Fudan University |
2023-12-05 | PHASE2 |
| NCT04460352 | RECRUITING | Esophageal Squamous Cell Carcinoma |
Karolinska University Hospital |
2020-11-27 | PHASE3 |
| NCT06751277 | NOT_YET_RECRUITING | Recurrent or Metastatic Endometrial Cancer |
xiang yang |
2025-02-01 | PHASE2 |
| NCT06684327 | RECRUITING | Paget Disease, Extramammary; Rhabdomyosarcoma; Testicular Cancer; Penile Cancer; Urachal Cancer |
Fudan University |
2024-11-30 | PHASE2 |
| NCT07245797 | NOT_YET_RECRUITING | Breast Cancer |
Zhimin Shao |
2025-12-15 | PHASE2 |
| NCT06400849 | RECRUITING | Non-metastatic Breast Cancer |
Centre Antoine Lacassagne |
2024-04-04 | |
| NCT06943820 | RECRUITING | Non-small Cell Lung Cancer Stage IIIB/IV; Head and Neck Squamous Cell Carcinoma (HNSCC); Colorectal Adenocarcinoma; Advanced Solid Tumors |
Akeso |
2025-05-21 | PHASE1; PHASE2 |
| NCT06202261 | RECRUITING | Metastatic Breast Cancer; Recurrent Breast Cancer; Advanced Malignancies |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2023-04-13 | PHASE1; PHASE2 |
| NCT07580833 | NOT_YET_RECRUITING | Metastatic Breast Cancer |
Health Hope Pharma |
2026-05 | PHASE1 |
| NCT02962063 | ACTIVE_NOT_RECRUITING | Esophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma |
Memorial Sloan Kettering Cancer Center |
2016-11 | PHASE1; PHASE2 |
| NCT07504770 | NOT_YET_RECRUITING | Paclitaxel-Induced Peripheral Neuropathy; Breast Cancer; Surgical Glove |
Necmettin Erbakan University |
2026-03-26 | |
| NCT06447662 | ACTIVE_NOT_RECRUITING | Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung |
Pfizer |
2024-06-27 | PHASE1 |
| NCT05451043 | RECRUITING | Pancreatic Cancer; Hepatocellular Cancer; Biliary Tract Cancer; Cholangiocarcinoma |
AHS Cancer Control Alberta |
2023-07-05 | PHASE2 |
| NCT05116462 | ACTIVE_NOT_RECRUITING | Non-Small Cell Lung Cancer |
Innovent Biologics (Suzhou) Co. Ltd. |
2024-03-15 | PHASE3 |
| NCT03085056 | ACTIVE_NOT_RECRUITING | Anaplastic Thyroid Cancer |
Memorial Sloan Kettering Cancer Center |
2017-03-15 | EARLY_PHASE1 |
| NCT05107674 | RECRUITING | Ovarian Cancer, Epithelial; Gastric Cancer; GastroEsophageal Junction (GEJ) Cancer; Head and Neck Squamous Cell Carcinoma; Metastatic or Unresectable Melanoma; Non-small Cell Lung Cancer (NSCLC); Metastatic Castration-resistant Prostate Cancer (mCRPC); Malignant Pleural Mesothelioma (MPM); Triple Negative Breast Cancer (TNBC); Metastatic Urothelial Carcinoma; Cervical Cancer; Diffuse Large B Cell Lymphoma (DLBCL); Richter Transformation; Microsatellite Stable Colorectal Carcinoma |
Nurix Therapeutics, Inc. |
2021-09-29 | PHASE1 |
| NCT05498896 | ACTIVE_NOT_RECRUITING | Triple Negative Breast Cancer |
Queen Mary University of London |
2018-12-19 | PHASE2 |
| NCT07125391 | RECRUITING | Ovarian Cancer |
Bai-Rong Xia |
2025-06-20 | PHASE2 |
| NCT06241469 | NOT_YET_RECRUITING | Gastric Cancer; GastroEsophageal Cancer; Adenocarcinoma |
Wu Jun |
2024-02-03 | PHASE2 |
| NCT04304248 | UNKNOWN | Non Small Cell Lung Cancer |
Hao Long |
2019-08-01 | PHASE2 |
| NCT06853678 | RECRUITING | Extensive Stage Small Cell Lung Cancer (ES-SCLC) |
Tianjin Medical University Cancer Institute and Hospital |
2025-02-28 | |
| NCT07699185 | RECRUITING | Esophageal Squamous Cell Carcinoma |
Tongji Hospital |
2024-01-29 | PHASE2 |
| NCT06690476 | RECRUITING | Esophageal Squamous Cell Carcinoma |
Peking University |
2024-10-10 | EARLY_PHASE1 |
| NCT06162468 | NOT_YET_RECRUITING | Intraductal Papillary Mucinous Neoplasm of Pancreas |
University of Auckland, New Zealand |
2025-05-31 | |
| NCT05298423 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Merck Sharp & Dohme LLC |
2022-05-03 | PHASE3 |
| NCT04862650 | ACTIVE_NOT_RECRUITING | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Metastatic Head and Neck Squamous Cell Carcinoma; Metastatic Hypopharyngeal Squamous Cell Carcinoma; Metastatic Laryngeal Squamous Cell Carcinoma; Metastatic Oral Cavity Squamous Cell Carcinoma; Metastatic Oropharyngeal Squamous Cell Carcinoma; Pathologic Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Recurrent Head and Neck Squamous Cell Carcinoma; Recurrent Hypopharyngeal Squamous Cell Carcinoma; Recurrent Laryngeal Squamous Cell Carcinoma; Recurrent Oral Cavity Squamous Cell Carcinoma; Recurrent Oropharyngeal Squamous Cell Carcinoma; Squamous Cell Carcinoma of Unknown Primary; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Oral Cavity Cancer AJCC v8; Stage IVA Hypopharyngeal Carcinoma AJCC v8; Stage IVA Laryngeal Cancer AJCC v8; Stage IVA Lip and Oral Cavity Cancer AJCC v8; Stage IVB Hypopharyngeal Carcinoma AJCC v8; Stage IVB Laryngeal Cancer AJCC v8; Stage IVB Lip and Oral Cavity Cancer AJCC v8; Stage IVC Hypopharyngeal Carcinoma AJCC v8; Stage IVC Laryngeal Cancer AJCC v8; Stage IVC Lip and Oral Cavity Cancer AJCC v8 |
Marcelo Bonomi |
2021-11-30 | PHASE2 |
| NCT06143748 | ACTIVE_NOT_RECRUITING | Esophagus Cancer |
Sun Yat-sen University |
2024-03-02 | PHASE2 |
| NCT06454435 | NOT_YET_RECRUITING | Gastric Cancer; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma |
Tianjin Medical University Cancer Institute and Hospital |
2024-06 | PHASE2 |
| NCT04015778 | ACTIVE_NOT_RECRUITING | Non Small Cell Lung Cancer |
Guangdong Association of Clinical Trials |
2019-08-08 | PHASE2 |
| NCT06398587 | WITHDRAWN | Locally Advanced Pancreatic Ductal Adenocarcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma |
OHSU Knight Cancer Institute |
2024-08-01 | PHASE2 |
| NCT04481204 | WITHDRAWN | Borderline Resectable Pancreatic Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma |
M.D. Anderson Cancer Center |
2023-04-18 | PHASE2 |
| NCT04638582 | TERMINATED | Lung Cancer, Nonsmall Cell |
McGill University Health Centre/Research Institute of the McGill University Health Centre |
2022-08-28 | PHASE2 |
| NCT05207709 | TERMINATED | Metastatic Breast Cancer |
SOLTI Breast Cancer Research Group |
2022-03-28 | PHASE3 |
| NCT05743270 | WITHDRAWN | Squamous Cell Carcinoma of Head and Neck; Locally Advanced Head and Neck Squamous Cell Carcinoma; Recurrent Head and Neck Squamous Cell Carcinoma |
Replimune, Inc. |
2024-01-30 | PHASE2 |
| NCT05978050 | UNKNOWN | Gastric or Esophagogastric Junction Adenocarcinoma |
Biotech Pharmaceutical Co., Ltd. |
2024-08-01 | PHASE3 |
| NCT05117476 | ACTIVE_NOT_RECRUITING | Advanced Solid Tumor; NSCLC |
Cullinan Therapeutics Inc. |
2021-10-29 | PHASE1 |
| NCT04872985 | ACTIVE_NOT_RECRUITING | Breast Cancer; Hormone-receptor Positive Breast Cancer |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2021-04-20 | PHASE2 |
| NCT05501665 | RECRUITING | Lung Non-Small Cell Carcinoma; Stage IV Lung Cancer AJCC v8; Stage III Lung Cancer |
Vanderbilt-Ingram Cancer Center |
2023-05-09 | PHASE1; PHASE2 |
| NCT05241249 | RECRUITING | Pancreas Cancer |
Susan E. Bates |
2022-02-01 | PHASE2 |
| NCT06140576 | NOT_YET_RECRUITING | Breast Neoplasms |
Zhejiang Cancer Hospital |
2023-11-30 | PHASE1; PHASE2 |
| NCT05640830 | RECRUITING | HER2-positive Advanced Gastric Cancer |
Kangbuk Samsung Hospital |
2023-01-01 | PHASE1; PHASE2 |
| NCT07117435 | RECRUITING | Colorectal Liver Metastases; First-line Treatment |
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. |
2025-05-13 | PHASE1 |
| NCT06867562 | NOT_YET_RECRUITING | Platinum-Resistant Primary Peritoneal Carcinoma; Platinum Resistant High Grade Epithelial Ovarian Cancer; Platinum Resistant High Grade Serous Ovarian Cancer |
Jina Pharmaceuticals Inc. |
2025-04 | PHASE3 |
| NCT02705196 | COMPLETED | Pancreatic Cancer |
Lokon Pharma AB |
2016-11 | PHASE1; PHASE2 |
| NCT06100497 | RECRUITING | Head and Neck Squamous Cell Carcinoma |
Beijing Tongren Hospital |
2023-10-01 | PHASE2 |
| NCT04649385 | COMPLETED | Advanced Solid Tumor |
BeiGene |
2021-03-04 | PHASE1 |
| NCT06679387 | RECRUITING | Breast Cancer Early Stage Breast Cancer (Stage 1-3) |
Ain Shams University |
2024-10-30 | PHASE2 |
| NCT05754853 | RECRUITING | Advanced or Metastatic Urothelium Cancer |
Shanghai Miracogen Inc. |
2023-04-06 | PHASE3 |
| NCT06786026 | RECRUITING | TNBC, Triple Negative Breast Cancer |
Fudan University |
2024-10-09 | PHASE2 |
| NCT06588335 | NOT_YET_RECRUITING | Esophageal Squamous Cell Carcinoma |
Henan Provincial People's Hospital |
2024-09-30 | PHASE2 |
| NCT05374512 | ACTIVE_NOT_RECRUITING | Breast Cancer |
AstraZeneca |
2022-05-16 | PHASE3 |
| NCT06018883 | UNKNOWN | Metastatic Pancreatic Adenocarcinoma |
Fudan University |
2023-08-20 | PHASE3 |
| NCT06486545 | UNKNOWN | Advanced Gastric Cancer |
Hunan Cancer Hospital |
2024-08-25 | |
| NCT06048926 | ENROLLING_BY_INVITATION | Esophageal Squamous Cell Carcinoma |
The First Affiliated Hospital with Nanjing Medical University |
2022-07-30 | |
| NCT05185869 | UNKNOWN | Pancreatic Cancer |
Ruijin Hospital |
2022-01 | PHASE2 |
| NCT03918278 | COMPLETED | Neoplasms |
Merck Sharp & Dohme LLC |
2019-06-19 | PHASE1 |
| NCT04046575 | ACTIVE_NOT_RECRUITING | Esophagus Cancer; Esophageal Cancer; Cancer of the Esophagus |
Washington University School of Medicine |
2019-11-07 | PHASE1 |
| NCT02520154 | COMPLETED | Stage III Fallopian Tube Cancer AJCC v7; Stage III Ovarian Cancer AJCC v6 and v7; Stage III Primary Peritoneal Cancer AJCC v7; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7 |
M.D. Anderson Cancer Center |
2016-07-05 | PHASE2 |
| NCT05908747 | COMPLETED | Pancreatic Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2023-05-31 | PHASE2 |
| NCT06472037 | UNKNOWN | Locally Advanced Pancreatic Ductal Adenocarcinoma |
Tianjin Medical University Cancer Institute and Hospital |
2024-07-01 | PHASE2 |
| NCT02429687 | RECRUITING | Ovarian Germ Cell Cancer; Ovarian Neoplasms; Ovarian Cancer |
Beihua Kong |
2015-04 | PHASE3 |
| NCT05312372 | Withdrawn | Esophageal Squamous Cell Carcinoma |
Institut de Recherches Internationales Servier|ADIR a Servier Group company|Servier |
2025-05 | Phase 1|Phase 2 |
| NCT03088540 | COMPLETED | Carcinoma,Non-Small-Cell Lung; Lung Carcinomas, Non-Small-Cell; Non-small-cell Lung Carcinoma; Nonsmall Cell Lung Cancer |
Regeneron Pharmaceuticals |
2017-05-29 | PHASE3 |
| NCT05673811 | COMPLETED | Pancreatic Adenocarcinoma; Metastatic |
Theriva Biologics SL |
2023-01-10 | PHASE2 |
| NCT05257408 | ACTIVE_NOT_RECRUITING | Ovarian Neoplasm; Fallopian Tube Neoplasms; Peritoneal Neoplasms |
Corcept Therapeutics |
2022-06-29 | PHASE3 |
| NCT04832854 | TERMINATED | Non-Small Cell Lung Cancer (NSCLC) |
Hoffmann-La Roche |
2021-04-23 | PHASE2 |
| NCT04222972 | TERMINATED | RET-fusion Non Small Cell Lung Cancer; Lung Neoplasm; Carcinoma, Non-Small-Cell Lung; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Disease; Carcinoma, Bronchogenic; Bronchial Diseases; Head and Neck Neoplasms; Adenocarcinoma; Carcinoma; Neoplasms by Histologic Type; Neoplasms, Germ Cell and Embryonal; Neoplasms, Nerve Tissue |
Hoffmann-La Roche |
2020-07-24 | PHASE3 |
| NCT03598426 | COMPLETED | Hypersensitivity Reactions |
Loma Linda University |
2018-08-08 | PHASE3 |
| NCT05178628 | UNKNOWN | Pancreatic Cancer; Thromboembolism |
Michalis Karamouzis |
2022-02-10 | PHASE3 |
| NCT05291910 | UNKNOWN | Breast Cancer |
Chinese Academy of Medical Sciences |
2022-03-12 | PHASE4 |
| NCT04547907 | RECRUITING | Breast Cancer,HER2-positive |
Henan Cancer Hospital |
2020-09-18 | PHASE3 |
| NCT04447092 | UNKNOWN | Pancreatic Cancer; Chemotherapy Effect |
Seoul National University Hospital |
2020-07-01 | PHASE2 |
| NCT06016413 | NOT_YET_RECRUITING | Head and Neck Squamous Cell Carcinoma |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2023-09-01 | PHASE2 |
| NCT06237257 | UNKNOWN | Locally Advanced Cervical Cancer |
Shanghai Shengdi Pharmaceutical Co., Ltd |
2024-03-20 | PHASE2 |
| NCT04876313 | UNKNOWN | Muscle-Invasive Bladder Carcinoma |
IRCCS San Raffaele |
2022-01-27 | PHASE2 |
| NCT01706120 | UNKNOWN | Ovarian Cancer |
National Cancer Institute, Naples |
2012-10 | PHASE4 |
| NCT02794571 | COMPLETED | Advanced/Metastatic Tumors |
Genentech, Inc. |
2016-05-23 | PHASE1 |
| NCT03750669 | COMPLETED | Pancreatic Adenocarcinoma Resectable; Neoadjuvant Chemotherapy |
Second Affiliated Hospital, Zhejiang University, School of Medicine |
2018-10-20 | PHASE3 |
| NCT05900921 | UNKNOWN | Advanced Squamous Non-Small-Cell Lung Cancer |
Sichuan University |
2023-07-01 | PHASE2 |
| NCT04958785 | TERMINATED | Triple-Negative Breast Cancer |
Gilead Sciences |
2021-12-14 | PHASE2 |
| NCT02584478 | UNKNOWN | Endometrial Carcinoma; Ovarian Carcinoma; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma; Cervical Carcinoma |
Advenchen Laboratories, LLC |
2015-12 | PHASE3 |
| NCT03107182 | COMPLETED | HPV-Related Squamous Cell Carcinoma; HNSCC |
University of Chicago |
2017-06-27 | PHASE2 |
| NCT04715542 | Not yet recruiting | Chemotherapy Induced Peripheral Neuropathy (CIPN) |
University of Bern|Insel Gruppe AG University Hospital Bern|Hospital of Thun|Tumor- und Brustzentrum ZeTuP St.Gallen|Gesundheitszentrum Fricktal AG|Kantonsspital Winterthur KSW|Kantonsspital Graubünden|Kantonsspital Aarau |
2024-08 | Phase 3 |
| NCT05715840 | UNKNOWN | Recurrent, or Metastatic Cervical Cancer With PD-L1 Positive (CPS≥1) |
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. |
2023-01-31 | PHASE3 |
| NCT04554524 | UNKNOWN | Thymoma and Thymic Carcinoma |
Tang-Du Hospital |
2020-08-27 | PHASE4 |
| NCT03393884 | ACTIVE_NOT_RECRUITING | Epithelial Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer |
Imunon |
2018-09-05 | PHASE1; PHASE2 |
| NCT05761470 | RECRUITING | Her-2 Negative Breast Cancer; HRR Gene Mutation |
Ying Lin |
2022-05-06 | PHASE2 |
| NCT04967417 | COMPLETED | Non-small Cell Lung Cancer |
Samsung Medical Center |
2022-05-26 | PHASE2 |
| NCT04643405 | TERMINATED | Advanced Pancreatic Cancer |
Ascentage Pharma Group Inc. |
2021-03-17 | PHASE1; PHASE2 |
| NCT05613088 | COMPLETED | Neoplasms, Ovarian |
Bristol-Myers Squibb |
2023-02-01 | PHASE2 |
| NCT04289792 | UNKNOWN | Pancreatic Neoplasms |
Fujian Medical University Union Hospital |
2020-05-09 | PHASE2 |
| NCT06387901 | Not yet recruiting | Breast Cancer|Paclitaxel Adverse Reaction|Chemotherapeutic Toxicity|Chemotherapeutic Agent Toxicity|Body Weight|Physical Inactivity |
Universitair Ziekenhuis Brussel|Vrije Universiteit Brussel|University Ghent |
2024-05-06 | -- |
| NCT05826015 | Not yet recruiting | Recurrent High Grade Uterine Cancer |
Washington University School of Medicine|National Cancer Institute (NCI)|Aravive Inc. |
2024-05-31 | Phase 1 |
| NCT05450042 | UNKNOWN | Peripheral Arterial Disease; Flow-mediated Dilation; Drug Eluting Balloon; Infrainguinal Peripheral Arterial Disease |
University Hospital, Essen |
2022-04-06 | |
| NCT05695313 | Recruiting | Breast Cancer |
Centre Georges Francois Leclerc |
2024-04-12 | Phase 2 |
| NCT05367206 | RECRUITING | Cervical Cancer; Neoadjuvant Chemotherapy; Bulky Neoplasm |
Sun Yat-sen University |
2022-03-14 | PHASE3 |
| NCT05872412 | UNKNOWN | Triple Negative Breast Cancer |
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
2023-06-01 | PHASE2 |
| NCT05159050 | TERMINATED | Peritoneal Carcinomatosis |
Carlos Chan |
2022-04-26 | PHASE1 |
| NCT05947201 | UNKNOWN | The Efficacy and Safety of Therapy Efficacy for Locally Advanced ESCC |
Weijia Fang, MD |
2023-05-08 | PHASE2 |
| NCT05611879 | UNKNOWN | NSCLC, Stage III |
Beijing Tsinghua Chang Gung Hospital |
2023-03-12 | PHASE2 |
| NCT01847326 | COMPLETED | Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Salivary Gland Squamous Cell Carcinoma; Tongue Cancer |
University of Chicago |
2013-03-26 | PHASE1 |
| NCT04077255 | UNKNOWN | Adenocarcinoma of the Stomach |
National Cancer Center, Korea |
2019-09-01 | PHASE2 |
| NCT05386888 | COMPLETED | NSCLC, Stage III |
Genfleet Therapeutics (Shanghai) Inc. |
2022-09-09 | PHASE2 |
| NCT00980954 | COMPLETED | Cervical Cancer |
Radiation Therapy Oncology Group |
2009-09 | PHASE3 |
| NCT04632992 | COMPLETED | Advanced Unresectable or Metastatic Solid Malignancy |
Genentech, Inc. |
2021-01-13 | PHASE2 |
| NCT02689427 | COMPLETED | Invasive Breast Carcinoma; Stage I Breast Cancer AJCC v7; Stage IA Breast Cancer AJCC v7; Stage IB Breast Cancer AJCC v7; Stage II Breast Cancer AJCC v6 and v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Triple-Negative Breast Carcinoma |
M.D. Anderson Cancer Center |
2016-09-22 | PHASE2 |
| NCT02501954 | COMPLETED | Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Stage IIIA Uterine Corpus Cancer; Stage IIIB Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer |
Women's Cancer Care Associates, LLC |
2015-03 | PHASE3 |
| NCT05669807 | UNKNOWN | Second Line Treatment of Gastric Cancer |
Zhejiang Cancer Hospital |
2022-12 | PHASE2 |
| NCT02436993 | ACTIVE_NOT_RECRUITING | Breast Carcinoma |
University of California, Irvine |
2015-04 | PHASE2 |
| NCT04865289 | COMPLETED | Endometrial Neoplasms |
Merck Sharp & Dohme LLC |
2019-10-22 | PHASE3 |
| NCT05552807 | UNKNOWN | Head and Neck Squamous Carcinoma |
Sinocelltech Ltd. |
2022-06-15 | PHASE1 |
| NCT03141359 | ACTIVE_NOT_RECRUITING | Lung Cancer Stage II; Lung Cancer Stage III; Non Small Cell Lung Cancer |
Wake Forest University Health Sciences |
2017-05-12 | PHASE2 |
| NCT04770272 | TERMINATED | Triple-negative Breast Cancer |
Palleos Healthcare GmbH |
2021-03-01 | PHASE2 |
| NCT04814485 | UNKNOWN | Pancreatic Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2021-04-22 | PHASE2 |
| NCT05449483 | UNKNOWN | Esophageal Squamous Cell Carcinoma by AJCC V8 Stage; Unresectable |
Tianjin Medical University Cancer Institute and Hospital |
2022-05-11 | PHASE2 |
| NCT05410847 | UNKNOWN | Gastric Cancer |
Hebei Medical University |
2022-06-30 | PHASE2 |
| NCT03815461 | UNKNOWN | Locally Advanced Pancreatic Cancer |
Chinese Academy of Medical Sciences |
2019-02-01 | PHASE2 |
| NCT04840290 | UNKNOWN | Non Small Cell Lung Cancer |
Tang-Du Hospital |
2019-06-01 | PHASE3 |
| NCT04310943 | COMPLETED | Lung Adenocarcinoma Stage IV |
Zhou Chengzhi |
2021-03-01 | PHASE2 |
| NCT05138159 | UNKNOWN | Metastatic Pancreatic Cancer |
Fudan University |
2021-12-01 | PHASE2 |
| NCT03003546 | COMPLETED | Recurrent Aggressive Non-Hodgkin Lymphoma; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Aggressive Non-Hodgkin Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Small Lymphocytic Lymphoma |
Mayo Clinic |
2019-04-25 | PHASE1 |
| NCT04038489 | WITHDRAWN | Breast Cancer; Estrogen Receptor-positive Breast Cancer |
University of Virginia |
2019-10-18 | PHASE2 |
| NCT05322499 | UNKNOWN | Stage IV Esophagus Squamous Cell Carcinoma |
Zhejiang Cancer Hospital |
2022-04-15 | PHASE2 |
| NCT04079192 | UNKNOWN | Coronary Artery Disease; In-Stent Restenosis |
Biosensors Europe SA |
2020-08-07 | |
| NCT00003927 | COMPLETED | Breast Cancer |
City of Hope Medical Center |
1999-05-18 | PHASE1 |
| NCT04209855 | COMPLETED | Epithelial Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer |
AbbVie |
2019-12-31 | PHASE3 |
| NCT04846634 | NOT_YET_RECRUITING | Resectable Locally Advanced Non-small Cell Lung Cancer |
Tianjin Medical University Cancer Institute and Hospital |
2021-08 | PHASE2 |
| NCT05566457 | UNKNOWN | Breast Cancer |
Chinese Academy of Medical Sciences |
2020-01-01 | PHASE2 |
| NCT04722718 | UNKNOWN | Breast Cancer |
Jiuda Zhao |
2021-02-01 | PHASE2 |
| NCT05207904 | UNKNOWN | Non-Small Cell Squamous Lung Cancer; Brain Metastases |
Sun Yat-sen University |
2021-06-17 | PHASE2 |
| NCT02390427 | COMPLETED | Metastatic Breast Cancer; Recurrent Breast Cancer |
Otto Metzger, MD |
2015-04-20 | PHASE1 |
| NCT03666832 | UNKNOWN | Metastatic Pancreatic Cancer |
Joon Oh Park |
2019-06-17 | PHASE1; PHASE2 |
| NCT02629718 | UNKNOWN | PFS; OS; Quality of Life |
Sun Yat-sen University |
2015-12 | PHASE3 |
| NCT04581343 | COMPLETED | Metastatic Pancreatic Ductal Adenocarcinoma |
Pancreatic Cancer Action Network |
2020-11-02 | PHASE1 |
| NCT05298696 | COMPLETED | Peripheral Neuropathy; Breast Cancer |
Mansoura University |
2022-03-28 | PHASE1; PHASE2 |
| NCT03535727 | COMPLETED | Adenocarcinoma; Pancreatic Neoplasms; Neoplasm, Glandular; Neoplasms; Neoplasms Pancreatic; Digestive System Neoplasm; Endocrine Gland Neoplasms; Digestive System Disease; Pancreatic Diseases; Endocrine System Diseases |
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins |
2018-06-21 | PHASE1; PHASE2 |
| NCT04422392 | TERMINATED | Non Small Cell Lung Cancer |
Shanghai Pulmonary Hospital, Shanghai, China |
2020-07-13 | PHASE2 |
| NCT02426281 | COMPLETED | Pancreatic Ductal Adenocarcinoma |
Samsung Medical Center |
2015-06-04 | PHASE2 |
| NCT03928314 | TERMINATED | Solid Tumor |
ORIC Pharmaceuticals |
2019-05-02 | PHASE1 |
| NCT03965689 | ACTIVE_NOT_RECRUITING | Metastatic Lung Non-Small Cell Squamous Carcinoma; Metastatic Lung Non-Squamous Non-Small Cell Carcinoma; Stage IIIB Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8; Unresectable Lung Non-Small Cell Carcinoma; Unresectable Lung Non-Squamous Non-Small Cell Carcinoma |
National Cancer Institute (NCI) |
2020-04-16 | PHASE2 |
| NCT04551950 | COMPLETED | Cervical Cancer |
EMD Serono Research & Development Institute, Inc. |
2020-10-19 | PHASE1 |
| NCT04825938 | NOT_YET_RECRUITING | Salivary Gland Malignant Neoplasms; Salivary Gland Tumors |
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
2021-04-30 | PHASE2 |
| NCT04390958 | UNKNOWN | Esophageal Squamous Cell Carcinoma |
Chinese Academy of Medical Sciences |
2020-05-15 | PHASE2 |
| NCT04659499 | UNKNOWN | Early Breast Cancer |
Peking Union Medical College Hospital |
2021-01 | PHASE2 |
| NCT04222790 | COMPLETED | Early Breast Cancer |
Henan Cancer Hospital |
2020-08-28 | PHASE2 |
| NCT03519308 | TERMINATED | Pancreatic Cancer |
Abramson Cancer Center at Penn Medicine |
2020-07-29 | EARLY_PHASE1 |
| NCT03539328 | UNKNOWN | Ovarian Cancer |
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano |
2018-06 | PHASE2 |
| NCT04203485 | UNKNOWN | PD-L1 Positive Non-small Cell Lung Cancer |
Jiangsu HengRui Medicine Co., Ltd. |
2020-06-15 | PHASE3 |
| NCT04063683 | UNKNOWN | Esophageal Squamous Cell Carcinoma |
Henan Cancer Hospital |
2019-10-07 | PHASE2 |
| NCT02564146 | COMPLETED | Metastatic Pancreatic Cancer; Adenocarcinoma of the Pancreas |
AIO-Studien-gGmbH |
2016-12 | PHASE2 |
| NCT04632342 | UNKNOWN | Radiation Pneumonitis; Lung Cancer |
Hanlim Pharm. Co., Ltd. |
2020-11 | PHASE2 |
| NCT02229149 | TERMINATED | Breast Neoplasms; Malignant Tumor of the Breast |
US Oncology Research |
2014-12 | PHASE2 |
| NCT04001569 | UNKNOWN | Solid Tumor; Stomach Cancer |
Seoul National University Bundang Hospital |
2019-05-14 | PHASE1; PHASE2 |
| NCT02420314 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Joseph J. Cullen, MD, FACS |
2015-04 | PHASE2 |
| NCT02617849 | UNKNOWN | Metastatic Malignant Melanoma |
Wilson Miller |
2016-05-19 | PHASE2 |
| NCT02684461 | COMPLETED | Non Small Cell Lung Cancer |
UNC Lineberger Comprehensive Cancer Center |
2016-09-13 | PHASE2 |
| NCT02954055 | COMPLETED | Breast Cancer |
ETOP IBCSG Partners Foundation |
2017-09-13 | PHASE2 |
| NCT03703063 | UNKNOWN | Pancreatic Adenocarcinoma |
Benaroya Research Institute |
2018-09-17 | PHASE1 |
| NCT01779050 | TERMINATED | Breast Neoplasms |
Washington University School of Medicine |
2013-12-19 | PHASE2 |
| NCT04210037 | TERMINATED | Small Cell Lung Cancer |
Ascentage Pharma Group Inc. |
2020-08-20 | PHASE1; PHASE2 |
| NCT04737967 | UNKNOWN | Oncology Pain; Chemotherapy-induced Peripheral Neuropathy |
Mendel AI |
2021-02-15 | PHASE2; PHASE3 |
| NCT04108013 | UNKNOWN | Lung Cancer Stage II; PD-1 Antibody; Non-small Cell Lung Cancer |
Xuanwu Hospital, Beijing |
2019-10-08 | PHASE2 |
| NCT04073537 | UNKNOWN | Squamous Non-small Cell Lung Cancer |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
2019-10-31 | PHASE3 |
| NCT02822157 | UNKNOWN | Ovarian Epithelial Cancer |
Universitaire Ziekenhuizen KU Leuven |
2016-08 | PHASE2 |
| NCT03019588 | TERMINATED | Gastric Neoplasms; Gastroesophageal Junction Adenocarcinoma |
Merck Sharp & Dohme LLC |
2017-02-16 | PHASE3 |
| NCT02550327 | COMPLETED | Pancreatic Adenocarcinoma |
Baylor Research Institute |
2016-01 | EARLY_PHASE1 |
| NCT01325441 | COMPLETED | Cancer |
Sumitomo Pharma America, Inc. |
2011-04 | PHASE1; PHASE2 |
| NCT03987867 | UNKNOWN | Non-small Cell Lung Cancer; First-line Treatment |
Tianjin Medical University Cancer Institute and Hospital |
2019-06-01 | PHASE1 |
| NCT04299880 | COMPLETED | Oncology |
Sumitomo Pharma America, Inc. |
2020-02-24 | PHASE1 |
| NCT04473716 | COMPLETED | Oral Cancer; Induction Chemotherapy; Programmed Cell Death 1 Inhibitor; Inductive Therapy |
Shanghai Jiao Tong University School of Medicine |
2020-07-30 | PHASE1 |
| NCT03314740 | COMPLETED | Ovarian Neoplasms |
Mario Negri Institute for Pharmacological Research |
2017-06-12 | PHASE2 |
| NCT03655080 | TERMINATED | Cord Compression |
Washington University School of Medicine |
2019-01-09 | PHASE2 |
| NCT03214250 | COMPLETED | Metastatic Pancreatic Adenocarcinoma |
Parker Institute for Cancer Immunotherapy |
2017-07-21 | PHASE1; PHASE2 |
| NCT04054362 | COMPLETED | Pancreatic Cancer |
Barts & The London NHS Trust |
2018-11-29 | PHASE2 |
| NCT03086369 | COMPLETED | Metastatic Pancreatic Cancer |
Eli Lilly and Company |
2017-06-22 | PHASE1; PHASE2 |
| NCT03901118 | COMPLETED | Ovarian Cancer |
Chipscreen Biosciences, Ltd. |
2019-07-01 | PHASE2 |
| NCT04239001 | UNKNOWN | Advanced Pancreatic Cancer |
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. |
2020-02 | |
| NCT03395080 | COMPLETED | Endometrial Cancer; Uterine Cancer; Ovarian Cancer; Carcinosarcoma |
Leap Therapeutics, Inc. |
2018-03-05 | PHASE2 |
| NCT02392637 | COMPLETED | Stage III Intrahepatic Cholangiocarcinoma AJCC v7; Stage IIIA Gallbladder Cancer AJCC v7; Stage IIIB Gallbladder Cancer AJCC v7; Stage IVA Gallbladder Cancer AJCC v7; Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7; Stage IVB Gallbladder Cancer AJCC v7; Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7; Unresectable Extrahepatic Bile Duct Carcinoma; Unresectable Gallbladder Carcinoma |
M.D. Anderson Cancer Center |
2015-04-02 | PHASE2 |
| NCT03636308 | UNKNOWN | Pancreatic Cancer |
Peking University |
2018-07-17 | PHASE2 |
| NCT03394885 | COMPLETED | Ovarian Cancer; Ovarian Neoplasms |
Duke University |
2018-06-19 | PHASE1; PHASE2 |
| NCT03912402 | UNKNOWN | Cervical Cancer; Cervical Cancer Metastatic; Cervical Cancer Recurrent |
Biocad |
2018-12-25 | PHASE2 |
| NCT03517176 | COMPLETED | Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma |
Lisata Therapeutics, Inc. |
2018-07-31 | PHASE1 |
| NCT02913274 | TERMINATED | Stenosis of Arteriovenous Dialysis Fistula |
Rennes University Hospital |
2017-03-20 | |
| NCT03117049 | COMPLETED | Non-Small Cell Lung Cancer |
Ono Pharmaceutical Co., Ltd. |
2017-06-13 | PHASE3 |
| NCT02628132 | COMPLETED | Breast Cancer |
King Faisal Specialist Hospital & Research Center |
2016-11 | PHASE1; PHASE2 |
| NCT03777579 | SUSPENDED | Triple Negative Breast Cancer |
CSPC ZhongQi Pharmaceutical Technology Co., Ltd. |
2018-12-21 | PHASE3 |
| NCT03057600 | COMPLETED | Triple Negative Breast Cancer; TNBC - Triple-Negative Breast Cancer |
Calithera Biosciences, Inc |
2017-05-01 | PHASE2 |
| NCT02427841 | COMPLETED | Pancreatic Adenocarcinoma; Resectable Pancreatic Carcinoma |
OHSU Knight Cancer Institute |
2016-01-21 | PHASE2 |
| NCT01270724 | COMPLETED | CNS Germ Cell Tumor |
Nationwide Children's Hospital |
2010-08 | PHASE2 |
| NCT02308553 | COMPLETED | Cutaneous Malignant Melanoma |
Prof. Dr. med. Dirk Schadendorf |
2015-03-17 | PHASE1; PHASE2 |
| NCT02551185 | COMPLETED | Advanced Solid Tumors |
Celgene |
2015-12-22 | PHASE1 |
| NCT01572038 | COMPLETED | Breast Neoplasms |
Hoffmann-La Roche |
2012-06-01 | PHASE3 |
| NCT02681432 | UNKNOWN | Epithelial Ovarian Cancer |
PEDRO VILLAREJO CAMPOS |
2012-01 | PHASE3 |
| NCT03625830 | UNKNOWN | Small Vessel Disease |
B. Braun Medical International Trading Company Ltd. |
2017-12-18 | |
| NCT03493854 | COMPLETED | Early Breast Cancer |
Hoffmann-La Roche |
2018-06-14 | PHASE3 |
| NCT02044601 | WITHDRAWN | Lung Cancer |
M.D. Anderson Cancer Center |
2014-06 | PHASE1; PHASE2 |
| NCT03344172 | TERMINATED | Pancreatic Cancer Resectable |
Nathan Bahary, MD |
2017-12-13 | PHASE2 |
| NCT02065687 | UNKNOWN | Endometrial Adenocarcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Undifferentiated Carcinoma; Recurrent Uterine Corpus Carcinoma; Stage III Uterine Corpus Cancer AJCC v7; Stage IIIA Uterine Corpus Cancer AJCC v7; Stage IIIB Uterine Corpus Cancer AJCC v7; Stage IIIC Uterine Corpus Cancer AJCC v7; Stage IV Uterine Corpus Cancer AJCC v7; Stage IVA Uterine Corpus Cancer AJCC v7; Stage IVB Uterine Corpus Cancer AJCC v7 |
Gynecologic Oncology Group |
2014-03-17 | PHASE2; PHASE3 |
| NCT02186847 | COMPLETED | Adenosquamous Lung Carcinoma; Bronchioloalveolar Carcinoma; Large Cell Lung Carcinoma; Lung Adenocarcinoma; Non-Small Cell Lung Carcinoma; Recurrent Non-Small Cell Lung Carcinoma; Squamous Cell Lung Carcinoma; Stage IIIA Non-Small Cell Lung Cancer; Stage IIIB Non-Small Cell Lung Cancer |
NRG Oncology |
2014-08 | PHASE2 |
| NCT03492047 | COMPLETED | Peripheral Neuropathy Due to Chemotherapy |
Ain Shams University |
2018-04-01 | PHASE1; PHASE2 |
| NCT03058939 | WITHDRAWN | Breast Cancer; Breast Cancer Stage II; Breast Cancer Stage III |
University of Chicago |
2018-11 | PHASE2 |
| NCT03307148 | COMPLETED | Pancreatic Adenocarcinoma |
Barts & The London NHS Trust |
2016-01-15 | PHASE1 |
| NCT03432598 | COMPLETED | Locally Advanced Lung Cancer; Metastatic Lung Cancer |
BeiGene |
2017-08-24 | PHASE2 |
| NCT02631876 | COMPLETED | Epithelial Ovarian Cancer; Primary Peritoneal Carcinoma; Fallopian Tube Cancer; Ovarian Cancer |
ImmunoGen, Inc. |
2016-03-02 | PHASE3 |
| NCT03169777 | WITHDRAWN | Colorectal Cancer |
ImmunityBio, Inc. |
2018-08 | PHASE1; PHASE2 |
| NCT02272790 | COMPLETED | Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation |
AstraZeneca |
2015-01-30 | PHASE2 |
| NCT03072992 | COMPLETED | Advanced Breast Cancer; Metastatic Breast Cancer |
National Center of Oncology, Armenia |
2017-03-20 | PHASE2 |
| NCT01367301 | TERMINATED | Stage IA Uterine Sarcoma; Stage IB Uterine Sarcoma; Stage IC Uterine Sarcoma; Stage IIA Uterine Sarcoma; Stage IIB Uterine Sarcoma; Stage IIIA Uterine Sarcoma; Stage IIIB Uterine Sarcoma; Stage IIIC Uterine Sarcoma; Stage IVA Uterine Sarcoma; Stage IVB Uterine Sarcoma; Uterine Carcinosarcoma |
Albert Einstein College of Medicine |
2011-07-08 | |
| NCT03574649 | WITHDRAWN | Non Small Cell Lung Cancer |
ImmunityBio, Inc. |
2018-06 | PHASE2 |
| NCT02194166 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2014-07-18 | PHASE3 |
| NCT01185171 | COMPLETED | Head and Neck Cancer |
University of Chicago |
2003-01-27 | PHASE2 |
| NCT02855788 | UNKNOWN | Metastatic Gastric Cancer; Locally Advanced Gastric Cancer |
Huashan Hospital |
2015-05 | PHASE2 |
| NCT02134067 | TERMINATED | Advanced Solid Tumors |
Taiho Oncology, Inc. |
2014-08 | PHASE1 |
| NCT02500810 | UNKNOWN | Neurotoxicity |
Peking University Cancer Hospital & Institute |
2015-07 | PHASE2 |
| NCT01628380 | UNKNOWN | Ovarian Neoplasms |
A.O. Ospedale Papa Giovanni XXIII |
2012-06 | PHASE3 |
| NCT02622074 | COMPLETED | Triple Negative Breast Neoplasms |
Merck Sharp & Dohme LLC |
2016-01-27 | PHASE1 |
| NCT02487277 | TERMINATED | Adenocarcinoma |
Andrew Ko |
2015-07-14 | PHASE2 |
| NCT01435018 | COMPLETED | HIV-1 Infection |
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections |
2013-10-01 | PHASE3 |
| NCT02685059 | COMPLETED | Breast Cancer |
GBG Forschungs GmbH |
2016-06 | PHASE2 |
| NCT02559674 | COMPLETED | Advanced Pancreatic Cancer |
Altor BioScience |
2016-07 | PHASE1 |
| NCT02967133 | TERMINATED | Non-Small-Cell Lung Cancer Metastatic; Non-Small Cell Carcinoma of Lung, TNM Stage 4; Nonsmall Cell Lung Cancer; Non Small Cell Lung Cancer Recurrent |
Alliance Foundation Trials, LLC. |
2016-12 | PHASE2 |
| NCT02470468 | COMPLETED | Stage IV Non-small Cell Lung Cancer |
SOTIO a.s. |
2014-12 | PHASE1; PHASE2 |
| NCT00997906 | UNKNOWN | Head and Neck Cancer |
National Cancer Centre, Singapore |
2009-09-15 | PHASE2; PHASE3 |
| NCT01971281 | UNKNOWN | Pancreatic Adenocarcinoma |
NovoCure Ltd. |
2013-11 | PHASE1; PHASE2 |
| NCT02012192 | TERMINATED | Epithelial Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer |
Medical University Innsbruck |
2014-07-04 | PHASE1; PHASE2 |
| NCT02539225 | COMPLETED | Metastatic Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma |
Eli Lilly and Company |
2015-10-05 | PHASE2 |
| NCT02344095 | COMPLETED | Epithelial Ovarian Carcinoma; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma |
Seoul National University Hospital |
2014-12 | PHASE1 |
| NCT02051868 | UNKNOWN | Squamous Cell Carcinoma of the Anus |
Royal Marsden NHS Foundation Trust |
2013-12 | PHASE2 |
| NCT03388892 | COMPLETED | Kidney Failure, Chronic; Angioplasty; Dialysis |
National Taiwan University Hospital Hsin-Chu Branch |
2015-01-29 | |
| NCT01862081 | COMPLETED | Breast Cancer, Non-small Lung Cancer |
Genentech, Inc. |
2013-07-16 | PHASE1 |
| NCT02506803 | UNKNOWN | Pancreatic Cancer |
Wakayama Medical University |
2015-07 | PHASE1 |
| NCT01654146 | UNKNOWN | Ovarian Cancer |
Medical Research Council |
2011-06 | PHASE3 |
| NCT01463072 | ACTIVE_NOT_RECRUITING | Locally Advanced Breast Carcinoma; Metastatic Breast Carcinoma; Recurrent Breast Carcinoma; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Stage IV Breast Cancer AJCC v6 and v7 |
City of Hope Medical Center |
2012-06-19 | PHASE2 |
| NCT01215136 | TERMINATED | Transitional Cell Carcinoma; Bladder Carcinoma; Urothelial Carcinoma |
Matthew Galsky |
2010-12 | PHASE2 |
| NCT02514421 | COMPLETED | Pancreatic Adenocarcinoma |
The University of Texas Health Science Center, Houston |
2015-07 | PHASE1 |
| NCT01701349 | WITHDRAWN | Anaplastic Thyroid Cancer |
Mateon Therapeutics |
2015-03 | PHASE3 |
| NCT02551055 | TERMINATED | Advanced and Metastatic Gastric or Gastroesophageal Adenocarcinoma |
Millennium Pharmaceuticals, Inc. |
2015-10-15 | PHASE1 |
| NCT01967199 | TERMINATED | Coronary Restenosis |
Seung-Jung Park |
2013-04-18 | PHASE4 |
| NCT00660218 | COMPLETED | Carcinoma, Squamous Cell |
State University of New York - Upstate Medical University |
2008-03 | PHASE1; PHASE2 |
| NCT02124317 | UNKNOWN | Advanced Pancreatic Cancer |
Chinese PLA General Hospital |
2014-04 | PHASE2 |
| NCT01953536 | WITHDRAWN | Breast Neoplasms |
Endocyte |
2014-04 | PHASE2 |
| NCT02429622 | COMPLETED | Esophageal Neoplasms |
Chinese Academy of Medical Sciences |
2015-01 | PHASE1; PHASE2 |
| NCT02772224 | UNKNOWN | Peripheral Arterial Disease |
Shanghai 10th People's Hospital |
2016-06 | PHASE1 |
| NCT01836432 | TERMINATED | Pancreatic Cancer; Pancreatic Carcinoma Non-resectable; Locally Advanced Malignant Neoplasm |
NewLink Genetics Corporation |
2013-05 | PHASE3 |
| NCT00575952 | COMPLETED | Endometrial Adenosquamous Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Mixed Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Squamous Cell Carcinoma; Endometrial Undifferentiated Carcinoma; Recurrent Uterine Corpus Carcinoma; Stage IIIA Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer; Stage IVB Uterine Corpus Cancer |
Gynecologic Oncology Group |
2008-01-17 | PHASE1 |
| NCT02319889 | TERMINATED | Stage I Non-Small Cell Lung Cancer; Stage II Non-Small Cell Lung Cancer |
Case Comprehensive Cancer Center |
2016-02-02 | EARLY_PHASE1 |
| NCT01962948 | TERMINATED | Recurrent Fallopian Tube Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Primary Peritoneal Cavity Cancer |
Fox Chase Cancer Center |
2013-10-09 | PHASE1; PHASE2 |
| NCT01216111 | COMPLETED | Triple Negative Breast Cancer |
Fudan University |
2011-01-01 | PHASE3 |
| NCT02570711 | TERMINATED | Metastatic Pancreatic Cancer |
Acerta Pharma BV |
2015-10-13 | PHASE2 |
| NCT01493843 | COMPLETED | Non-Small Cell Lung Cancer |
Genentech, Inc. |
2012-01-20 | PHASE2 |
| NCT01186991 | COMPLETED | Breast Cancer |
Genentech, Inc. |
2011-03 | PHASE2 |
| NCT01256268 | COMPLETED | Endometrial Cancer; Ovarian Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2011-06-13 | PHASE1 |
| NCT01858883 | COMPLETED | Solid Tumors; Pancreatic Cancer |
Incyte Corporation |
2013-06 | PHASE1; PHASE2 |
| NCT01280058 | COMPLETED | Pancreatic Acinar Cell Carcinoma; Pancreatic Ductal Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage IV Pancreatic Cancer |
National Cancer Institute (NCI) |
2010-12 | PHASE2 |
| NCT02016274 | UNKNOWN | Esophageal Squamous Cell Cancer |
Shen Lin |
2013-12 | PHASE2 |
| NCT00933426 | TERMINATED | Prostate Cancer |
M.D. Anderson Cancer Center |
2009-08 | PHASE1 |
| NCT01970579 | COMPLETED | Stenosis; Restenosis |
B. Braun Melsungen AG |
2013-10 | PHASE3 |
| NCT01496742 | COMPLETED | Non-Squamous Non-Small Cell Lung Cancer |
Genentech, Inc. |
2012-04 | PHASE2 |
| NCT00617409 | COMPLETED | Small Cell Lung Cancer |
H. Lee Moffitt Cancer Center and Research Institute |
2007-10-02 | PHASE2 |
| NCT01694576 | TERMINATED | Nasopharyngeal Carcinoma |
Jiangsu Cancer Institute & Hospital |
2012-09 | PHASE2 |
| NCT01936974 | TERMINATED | Ovarian Carcinoma; Fallopian Tube Carcinoma; Peritoneal Carcinoma |
Western Regional Medical Center |
2013-09 | PHASE2 |
| NCT01746771 | COMPLETED | HER-2 Positive Advanced Gastric Cancer |
Hanmi Pharmaceutical Company Limited |
2012-11 | PHASE1; PHASE2 |
| NCT02474186 | COMPLETED | Breast Cancer; Metastatic Breast Cancer; Solid Tumor |
NYU Langone Health |
2003-04 | PHASE2 |
| NCT01317615 | COMPLETED | Carcinoma, Large Cell; Neuroendocrine Tumors |
Novartis Pharmaceuticals |
2011-04 | PHASE4 |
| NCT01764022 | COMPLETED | Human Epithelial Receptor (HER)-2 Positive Breast Cancer |
Biocad |
2012-10 | PHASE3 |
| NCT00108745 | UNKNOWN | Fallopian Tube Clear Cell Adenocarcinoma; Fallopian Tube Endometrioid Adenocarcinoma; Fallopian Tube Mucinous Adenocarcinoma; Fallopian Tube Serous Adenocarcinoma; Fallopian Tube Transitional Cell Carcinoma; Fallopian Tube Undifferentiated Carcinoma; Ovarian Brenner Tumor; Ovarian Clear Cell Adenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Adenocarcinoma; Ovarian Seromucinous Carcinoma; Ovarian Serous Adenocarcinoma; Ovarian Transitional Cell Carcinoma; Ovarian Undifferentiated Carcinoma; Primary Peritoneal Serous Adenocarcinoma; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7 |
GOG Foundation |
2005-03-21 | PHASE3 |
| NCT02065466 | WITHDRAWN | Metastatic Melanoma; Brain Metastases |
University of Arizona |
2014-07 | PHASE1; PHASE2 |
| NCT01487226 | UNKNOWN | Cervical Cancer |
Korean Gynecologic Oncology Group |
2008-01 | PHASE2 |
| NCT01851174 | TERMINATED | Pancreatic Carcinoma Non-resectable; Stage IV Pancreatic Cancer |
Western Regional Medical Center |
2013-02 | PHASE2 |
| NCT01309607 | UNKNOWN | ErbB2-Positive Stage I-III Breast Cancer |
National University Hospital, Singapore |
2011-04 | PHASE2 |
| NCT01454778 | COMPLETED | Peripheral Vascular Disease |
Patrick Kelly |
2011-04 | |
| NCT01688791 | TERMINATED | Advanced Cancer |
Endocyte |
2012-12 | PHASE1 |
| NCT01086696 | TERMINATED | Breast Cancer; Lung Cancer; Renal Cancer; Adrenal Cancer |
National Cancer Institute (NCI) |
2010-03-09 | EARLY_PHASE1 |
| NCT00602797 | COMPLETED | Recurrent Non-Small Cell Lung Carcinoma; Stage IV Non-Small Cell Lung Cancer |
University of Nebraska |
2007-12-17 | PHASE2 |
| NCT00976911 | COMPLETED | Ovarian Cancer |
Hoffmann-La Roche |
2009-10-29 | PHASE3 |
| NCT01570582 | UNKNOWN | Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cancer |
Korean Gynecologic Oncology Group |
2010-03 | PHASE2 |
| NCT01594684 | UNKNOWN | Catherization |
Prof. Dr. med. Gunnar Tepe |
2012-01 | PHASE2; PHASE3 |
| NCT01236716 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Chinese Society of Lung Cancer |
2010-11 | PHASE2 |
| NCT01085136 | COMPLETED | Carcinoma, Non-Small-Cell Lung |
Boehringer Ingelheim |
2010-02 | PHASE3 |
| NCT01293630 | COMPLETED | Advanced Solid Tumors |
Sanofi |
2011-01 | PHASE1 |
| NCT01268059 | TERMINATED | Non-small Cell Lung Cancer |
MedImmune LLC |
2010-12-16 | PHASE1; PHASE2 |
| NCT01200342 | TERMINATED | Melanoma |
M.D. Anderson Cancer Center |
2010-12 | PHASE2 |
| NCT00998192 | COMPLETED | Metastatic or Recurrent Squamous Cell Carcinoma of the Lung |
Oncolytics Biotech |
2009-10 | PHASE2 |
| NCT00915018 | COMPLETED | Breast Cancer |
Puma Biotechnology, Inc. |
2009-08-21 | PHASE2 |
| NCT00887575 | COMPLETED | Breast Cancer |
SCRI Development Innovations, LLC |
2009-06 | PHASE1; PHASE2 |
| NCT01617928 | COMPLETED | Solid Tumors |
AbbVie (prior sponsor, Abbott) |
2012-05 | PHASE1 |
| NCT01263613 | COMPLETED | Breast Cancer |
University of Wisconsin, Madison |
2010-12 | EARLY_PHASE1 |
| NCT01579578 | TERMINATED | Metastatic, Gastric or Gastro-oesophageal Junction, Cancer |
AstraZeneca |
2012-04 | PHASE2 |
| NCT01321775 | UNKNOWN | Breast Cancer |
Hospital Universitario Madrid Sanchinarro |
2009-08 | PHASE2 |
| NCT00876486 | COMPLETED | Breast Cancer |
Samyang Biopharmaceuticals Corporation |
2008-12 | PHASE3 |
| NCT00948675 | COMPLETED | Advanced Non-Small Cell Lung Cancer |
Eli Lilly and Company |
2009-09-01 | PHASE3 |
| NCT01364012 | COMPLETED | Non-Small Cell Lung Cancer |
Hoffmann-La Roche |
2011-05-23 | PHASE3 |
| NCT01527864 | UNKNOWN | Non Small Cell Lung Cancer |
Beijing Protgen Biotechnology Development Co., Ltd. |
2011-05 | PHASE2 |
| NCT01229930 | COMPLETED | Cervical Cancer |
University of Glasgow |
2010-06 | PHASE2 |
| NCT01042925 | COMPLETED | Breast Cancer; Breast Neoplasms |
Sanofi |
2010-02 | PHASE1; PHASE2 |
| NCT00960297 | TERMINATED | Non-Small Cell Lung Cancer |
SCRI Development Innovations, LLC |
2009-08 | PHASE2 |
| NCT01196741 | COMPLETED | Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer |
University College, London |
2011-03 | PHASE2; PHASE3 |
| NCT01593306 | UNKNOWN | Carcinoma Cervix |
Indira Gandhi Medical College, Shimla |
2011-07 | PHASE3 |
| NCT01161186 | COMPLETED | Pancreatic Neoplasms; Pancreatic Cancer; Adenocarcinoma |
University of California, San Francisco |
2010-07 | PHASE1 |
| NCT01083537 | TERMINATED | Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer; Bowel Obstruction |
University Health Network, Toronto |
2010-02 | PHASE1; PHASE2 |
| NCT02133612 | COMPLETED | Esophageal Cancer |
Chinese Academy of Medical Sciences |
2007-12 | PHASE2 |
| NCT00823186 | UNKNOWN | Cervical Cancer |
Chang Gung Memorial Hospital |
2009-02 | PHASE1 |
| NCT00281515 | COMPLETED | Epithelial Ovarian Cancer |
AGO Study Group |
2006-01 | PHASE2 |
| NCT01336049 | UNKNOWN | Esophageal Squamous Cell Cancer |
Peking University |
2011-03 | PHASE2 |
| NCT00954642 | COMPLETED | Solid Cancers |
Genentech, Inc. |
2009-08 | PHASE1 |
| NCT00846027 | COMPLETED | Breast Cancer |
Hoffmann-La Roche |
2009-01 | PHASE2 |
| NCT01264328 | COMPLETED | Head and Neck Cancer |
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello |
2011-03-09 | PHASE2 |
| NCT00550537 | COMPLETED | Lung Cancer |
Vanderbilt-Ingram Cancer Center |
2007-10 | PHASE2 |
| NCT00301028 | COMPLETED | Head and Neck Cancer |
M.D. Anderson Cancer Center |
2006-04 | PHASE2 |
| NCT01329640 | TERMINATED | Locally Advanced HER2-positive Breast Cancer |
Instituto do Cancer do Estado de São Paulo |
2010-09 | PHASE2 |
| NCT00870038 | UNKNOWN | Angioplasty, Transluminal, Percutaneous Coronary; Percutaneous Coronary Intervention |
Ospedale della Misericordia |
2010-12 | PHASE4 |
| NCT00626561 | TERMINATED | Cervical Cancer; Uterine Cancer |
M.D. Anderson Cancer Center |
2008-02 | PHASE2 |
| NCT00231868 | COMPLETED | Uterine Cancer |
Montefiore Medical Center |
2001-12 | PHASE2 |
| NCT00334321 | COMPLETED | Endometrial Cancer |
Washington University School of Medicine |
2006-04 | PHASE1 |
| NCT00256243 | COMPLETED | Breast Cancer |
Rita Sanghvi, Mehta |
2004-04 | PHASE2 |
| NCT00572078 | COMPLETED | SOLID TUMORS |
Safi Shahda |
2008-01-23 | PHASE1 |
| NCT00634595 | UNKNOWN | Head and Neck Squamous Carcinoma; Nasopharyngeal Carcinoma |
Sun Yat-sen University |
2008-03 | PHASE2 |
| NCT01240642 | TERMINATED | Metastatic Cancer With Impaired Renal Function; Metastatic Cancer With Normal Renal Function |
Novartis Pharmaceuticals |
2010-01 | PHASE1 |
| NCT00584909 | TERMINATED | Uterine Cancer |
University of Alabama at Birmingham |
2006-03 | PHASE2 |
| NCT00517621 | COMPLETED | Ovarian Cancer; Fallopian Tube Cancer; Peritoneal Neoplasms |
ARCAGY/ GINECO GROUP |
2006-02 | PHASE2 |
| NCT00550771 | COMPLETED | Breast Neoplasm |
Merck Sharp & Dohme LLC |
2007-07-16 | PHASE2 |
| NCT00404144 | COMPLETED | Coronary Stenosis |
Heart Centre Rotenburg |
2006-01 | PHASE2 |
| NCT00662129 | COMPLETED | Breast Cancer |
Alliance for Clinical Trials in Oncology |
2008-11 | PHASE2 |
| NCT00716417 | COMPLETED | Neoplasms |
Boehringer Ingelheim |
2008-07-01 | PHASE1 |
| NCT00687817 | COMPLETED | Non-small Cell Lung Cancer |
Peregrine Pharmaceuticals |
2008-06 | PHASE2 |
| NCT00919880 | COMPLETED | Breast Cancer |
Tao OUYANG |
2009-07 | PHASE2 |
| NCT00934752 | COMPLETED | Coronary Artery Stenosis |
C. R. Bard |
2009-07 | PHASE1; PHASE2 |
| NCT00496028 | COMPLETED | Neoplasms |
AstraZeneca |
2007-03 | PHASE1 |
| NCT00455533 | COMPLETED | Breast Cancer |
Bristol-Myers Squibb |
2007-10 | PHASE2 |
| NCT00533936 | UNKNOWN | Breast Cancer |
Instituto Nacional de Cancerologia, Columbia |
2006-09 | PHASE2 |
| NCT00457119 | COMPLETED | Non Small Cell Lung Cancer |
Novartis Pharmaceuticals |
2007-02 | PHASE1 |
| NCT00495664 | COMPLETED | Acute Myocardial Infarction |
The Hospital District of Satakunta |
2005-12 | |
| NCT00786110 | UNKNOWN | Adrenocortical Carcinoma |
University of Turin, Italy |
2008-04 | PHASE2 |
| NCT00708812 | COMPLETED | Advanced Non-small Cell Lung Cancer |
Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd |
2007-07 | PHASE2 |
| NCT00704145 | COMPLETED | Coronary Artery Disease |
A.O. Ospedale Papa Giovanni XXIII |
2007-11 | PHASE4 |
| NCT00610714 | COMPLETED | Ovarian Neoplasms; Ovarian Cancer |
AstraZeneca |
2008-04 | PHASE2 |
| NCT00407888 | COMPLETED | Estrogen Receptor-positive Breast Cancer; HER2-positive Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer |
University of Washington |
2006-05 | PHASE2 |
| NCT00434252 | COMPLETED | Melanoma |
Genentech, Inc. |
2007-02 | PHASE2 |
| NCT00508625 | COMPLETED | Non-Small Cell Lung Cancer |
Amgen |
2006-06 | PHASE2 |
| NCT00113516 | COMPLETED | Non-small Cell Lung Cancer |
Pfizer |
2005-09 | PHASE2 |
| NCT00189553 | COMPLETED | Ovarian Cancer; Fallopian Tube Cancer |
ARCAGY/ GINECO GROUP |
2005-04 | PHASE3 |
| NCT00971867 | COMPLETED | Head and Neck Cancer |
Bristol-Myers Squibb |
2006-08-04 | PHASE2 |
| NCT00666692 | COMPLETED | Non-small Cell Lung Cancer |
Abbott |
2008-04 | PHASE1 |
| NCT02004093 | COMPLETED | Ovarian Cancer |
Hoffmann-La Roche |
2005-12 | PHASE2 |
| NCT00130546 | COMPLETED | Coronary Artery Disease |
University Hospital Freiburg |
2004-11 | PHASE3 |
| NCT00606125 | COMPLETED | Neoplasms |
Bayer |
2007-05 | PHASE1 |
| NCT00497367 | COMPLETED | Cardiovascular Diseases |
Boston Scientific Corporation |
2007-07 | PHASE1 |
| NCT00133237 | COMPLETED | Coronary Disease |
Deutsches Herzzentrum Muenchen |
2005-07 | PHASE4 |
| NCT00752362 | COMPLETED | Coronary Restenosis |
Sahajanand Medical Technologies Limited |
2006-03 | PHASE4 |
| NCT00369070 | TERMINATED | Advanced Non-squamous NSCLC |
Amgen |
2007-01-31 | PHASE2 |
| NCT00561795 | COMPLETED | Primary Peritoneal Carcinoma; Tumor; Epithelial Ovarian Cancer; Uterine Disease; Cervix Diseases; Neoplasms, Ovarian; Cancer |
GlaxoSmithKline |
2007-09 | PHASE2 |
| NCT00158379 | COMPLETED | Ovarian Cancer |
North Eastern German Society of Gynaecological Oncology |
2003-07 | PHASE2 |
| NCT00094861 | COMPLETED | Dysphagia; Non-Small Cell Lung Cancer; Lung Cancer |
Swedish Orphan Biovitrum |
2005-01 | PHASE2 |
| NCT00068757 | COMPLETED | Breast Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
2003-08 | PHASE1 |
| NCT00307255 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
UNC Lineberger Comprehensive Cancer Center |
2006-08 | PHASE1 |
| NCT00085501 | COMPLETED | Lung Cancer |
SWOG Cancer Research Network |
2004-07 | PHASE2 |
| NCT00387374 | COMPLETED | Adenosquamous Cell Lung Cancer; Drug/Agent Toxicity by Tissue/Organ; Hemoptysis; Squamous Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer |
National Cancer Institute (NCI) |
2006-10 | PHASE2 |
| NCT00004125 | COMPLETED | Breast Cancer |
Eastern Cooperative Oncology Group |
1999-11-16 | PHASE3 |
| NCT00095914 | COMPLETED | Unspecified Adult Solid Tumor, Protocol Specific |
National Institutes of Health Clinical Center (CC) |
2004-09 | PHASE1 |
| NCT00146562 | COMPLETED | Breast Cancer; Stage I Breast Cancer; Stage II Breast Cancer |
Harold J. Burstein, MD, PhD |
2003-07 | PHASE2 |
| NCT00085839 | COMPLETED | Non-Small Cell Lung Cancer |
OSI Pharmaceuticals |
2004-02 | PHASE2 |
| NCT00014118 | COMPLETED | Head and Neck Cancer |
Eastern Cooperative Oncology Group |
2001-06-06 | PHASE2 |
| NCT00094835 | COMPLETED | Lung Cancer; Non-Small Cell Lung Cancer |
Amgen |
2005-01 | PHASE1; PHASE2 |
| NCT00113438 | COMPLETED | Cancer; Tumor |
Mateon Therapeutics |
2005-03 | PHASE2 |
| NCT00301080 | TERMINATED | Neurotoxicity; Pain; Breast Cancer |
Northwestern University |
2006-02 | PHASE3 |
| NCT00005046 | COMPLETED | Ovarian Cancer; Primary Peritoneal Cavity Cancer |
Gynecologic Oncology Group |
2000-04 | PHASE1 |
| NCT00255762 | COMPLETED | Recurrent Melanoma; Stage IV Melanoma |
National Cancer Institute (NCI) |
2005-12 | PHASE2 |
| NCT00111787 | COMPLETED | Neoplasms, Breast |
GlaxoSmithKline |
2005-04-11 | PHASE2 |
| NCT00106587 | COMPLETED | Coronary Restenosis |
University Hospital, Saarland |
2003-12 | PHASE1; PHASE2 |
| NCT00039780 | COMPLETED | Breast Neoplasms; Breast Diseases; Metastases, Neoplasm |
BioNumerik Pharmaceuticals, Inc. |
2001-09 | PHASE3 |
| NCT00161278 | TERMINATED | Advanced Non-Small Cell Lung Cancer |
University of Michigan Rogel Cancer Center |
2004-12 | PHASE2 |
| NCT00026104 | COMPLETED | Adenocarcinoma of the Pancreas; Stage II Pancreatic Cancer; Stage III Pancreatic Cancer |
National Cancer Institute (NCI) |
2001-11 | PHASE2 |
| NCT00062062 | COMPLETED | Lung Cancer |
Alliance for Clinical Trials in Oncology |
2004-10 | PHASE2 |
| NCT00055835 | COMPLETED | Bladder Cancer; Urethral Cancer |
SWOG Cancer Research Network |
2002-11 | PHASE2 |
| NCT00002984 | COMPLETED | Esophageal Cancer |
UNC Lineberger Comprehensive Cancer Center |
1997-03 | PHASE1; PHASE2 |
| NCT00532285 | TERMINATED | Breast Cancer |
National Cancer Center, Korea |
2005-09 | PHASE2 |
| NCT00021333 | COMPLETED | Head and Neck Cancer; Lung Cancer |
Fox Chase Cancer Center |
1999-09 | PHASE2 |
| NCT00280787 | COMPLETED | Non Small Cell Lung Cancer |
UNC Lineberger Comprehensive Cancer Center |
2003-11 | PHASE2 |
| NCT00136175 | COMPLETED | Bladder Cancer |
University of Michigan Rogel Cancer Center |
1999-11 | PHASE2 |
| NCT01023204 | COMPLETED | Breast Cancer |
Bristol-Myers Squibb |
2002-10 | PHASE2 |
| NCT00006248 | COMPLETED | Head and Neck Cancer |
SWOG Cancer Research Network |
2000-11 | PHASE2 |
| NCT00003614 | COMPLETED | Prostate Cancer |
Eastern Cooperative Oncology Group |
1999-02-04 | PHASE2 |
| NCT00004055 | COMPLETED | Lung Cancer |
Alliance for Clinical Trials in Oncology |
1999-11 | PHASE2 |
| NCT00003691 | COMPLETED | Endometrial Cancer |
Gynecologic Oncology Group |
1998-12 | PHASE3 |
| NCT00038246 | COMPLETED | Prostate Cancer |
M.D. Anderson Cancer Center |
2000-10 | PHASE1; PHASE2 |
| NCT00003624 | TERMINATED | Cervical Cancer; Endometrial Cancer; Fallopian Tube Cancer; Neurotoxicity; Ovarian Cancer; Primary Peritoneal Cavity Cancer; Sarcoma |
Gynecologic Oncology Group |
1998-12 | PHASE2 |
| NCT00299026 | COMPLETED | Coronary Artery Disease |
Boston Scientific Corporation |
2001-06 | PHASE2 |
| NCT00170664 | COMPLETED | Ovarian Cancer |
North Eastern German Society of Gynaecological Oncology |
1999-01 | PHASE2 |
| NCT00003587 | COMPLETED | Lung Cancer |
SWOG Cancer Research Network |
1998-10 | PHASE2 |
| NCT00003589 | COMPLETED | Lung Cancer |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-08 | PHASE3 |
| NCT00003230 | COMPLETED | Leukemia |
Swiss Cancer Institute |
1998-01 | PHASE1; PHASE2 |
| NCT00003378 | TERMINATED | Ovarian Cancer; Primary Peritoneal Cavity Cancer |
Gynecologic Oncology Group |
1998-08 | PHASE1 |
| NCT00074854 | COMPLETED | Lung Neoplasms |
Pfizer |
2002-05 | PHASE1; PHASE2 |
| NCT00088088 | COMPLETED | Stage IIIB Non-Small Cell Lung Cancer; Stage IV Non-Small Cell Lung Cancer |
Synta Pharmaceuticals Corp. |
2004-03 | PHASE1; PHASE2 |
| NCT00340184 | COMPLETED | Cervical Cancer |
Korean Gynecologic Oncology Group |
2004-08 | PHASE2 |
| NCT00003327 | UNKNOWN | Head and Neck Cancer |
Theradex |
1997-09 | PHASE2 |
| NCT00006049 | UNKNOWN | Lung Cancer |
AstraZeneca |
2000-05 | PHASE3 |
| NCT00003643 | UNKNOWN | Extragonadal Germ Cell Tumor; Teratoma; Testicular Germ Cell Tumor |
European Organisation for Research and Treatment of Cancer - EORTC |
1998-10 | PHASE2; PHASE3 |
| NCT00002917 | COMPLETED | Bladder Cancer |
Mary Babb Randolph Cancer Center at West Virginia University Hospitals |
1996-11 | PHASE1; PHASE2 |
| NCT01224652 | UNKNOWN | Gastric Cancer |
Korean Cancer Study Group |
PHASE3 | |
| NCT00046514 | COMPLETED | Breast Neoplasms; Metastases, Neoplasm |
Celgene Corporation |
2001-06 | PHASE2 |
| NCT00301730 | COMPLETED | Breast Cancer; Metastatic Cancer |
National Cancer Institute (NCI) |
2005-10 | PHASE1 |
| NCT00189566 | COMPLETED | Ovarian Cancer; Fallopian Tube Cancer; Malignant Tumor of Peritoneum |
ARCAGY/ GINECO GROUP |
2004-04 | PHASE2 |
| NCT00019812 | COMPLETED | Breast Cancer |
National Institutes of Health Clinical Center (CC) |
1999-08 | PHASE2 |
| NCT00154778 | COMPLETED | Gastric Cancer |
National Taiwan University Hospital |
2003-03 | PHASE2 |
| NCT00477867 | WITHDRAWN | Ovarian Cancer |
Gynecologic Oncology Group |
(data from https://clinicaltrials.gov, updated on 2026-04-14)
Mechanism and Biochemical Profile
Appendix RUO and cGMP Quality Standards
| Quality Dimension | RUO (Research Use Only) | cGMP (Current Good Manufacturing Practice) |
|---|---|---|
| Clinical Applicability | Prohibited in human clinical trials or medical diagnostics. | Mandatory for human clinical trials (Phase I–III) and therapies. |
| Regulatory Status | Non-regulated grade; exempt from drug manufacturing laws. | Legally enforced by health authorities (e.g., FDA, EMA, NMPA). |
| Facility Environment | Unclassified analytical or research laboratories. | Validated Cleanrooms (ISO Class 5–8) with continuous monitoring. |
| Quality Control | Basic purity and activity testing. | Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma). |
| Process Validation | Basic equipment calibration; no process validation required. | Full qualification (IQ/OQ/PQ) and complete batch records. |
| Quality Assurance | Vendor self-declared without required formal QMS. | Mandatory QA/QC unit, Change Control, CAPA, and vendor audits. |
| Regulatory Impact | High risk of IND rejection if used as a critical raw material. | Required for IND/NDA filings, supported by Drug Master Files (DMF). |
Footnotes
Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).
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