Clinical Trials

Numerous clinical trials evaluate the therapeutic efficacy and safety of paclitaxel across early- to late-phase investigations. These studies address conditions such as breast cancer, esophageal squamous cell carcinoma, recurrent high-grade uterine cancer, pancreatic cancer, chemotherapy-induced peripheral neuropathy, and coronary artery disease. Sponsored by academic medical centers, government institutes like the National Cancer Institute, and corporate entities such as Servier and Biotronik AG, their recruitment statuses include actively recruiting, completed, not yet recruiting, and withdrawn.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07528768 NOT_YET_RECRUITING
Triple Negative Breast Cancer; Metastatic Triple-negative Breast Cancer
AntiCancer Research Jamaica
2026-06-01 PHASE2
NCT04198766 RECRUITING
Solid Tumor; Non-Small Cell Lung Cancer; Head and Neck Cancer; Melanoma; Gastric Cancer; Renal Cell Carcinoma; Urothelial Carcinoma; Resectable Non-Small-Cell Lung Cancer
Inhibrx Biosciences, Inc
2019-12-10 PHASE1; PHASE2
NCT06714604 RECRUITING
Locally Advanced Pancreatic Adenocarcinoma; Borderline Resectable Pancreatic Carcinoma; Pancreas Cancer; Neoadjuvant Chemotherapy; Surgery; Pancreatectomy
Sahlgrenska University Hospital
2023-10-18 PHASE3
NCT07629817 RECRUITING
Esophageal Squamous Cell Carcinoma
Henan Cancer Hospital
2026-06-16 PHASE3
NCT07346196 NOT_YET_RECRUITING
Squamous Cell Carcinoma
University of Chicago
2027-02-07 PHASE2
NCT05919537 ACTIVE_NOT_RECRUITING
Non-Small Cell Lung Cancer; Pancreatic Cancer; Locally Advanced Solid Tumor; Metastatic Solid Tumor
Hummingbird Bioscience
2023-09-06 PHASE1
NCT01042379 RECRUITING
Breast Neoplasms; Breast Cancer; Breast Tumors; Angiosarcoma; TNBC - Triple-Negative Breast Cancer; HER2-positive Breast Cancer; HER2-negative Breast Cancer; Hormone Receptor Positive Tumor; Hormone Receptor Negative Tumor; Early-stage Breast Cancer; Locally Advanced Breast Cancer
QuantumLeap Healthcare Collaborative
2010-03-01 PHASE2
NCT07001618 RECRUITING
NSCLC (Advanced Non-small Cell Lung Cancer)
Gustave Roussy, Cancer Campus, Grand Paris
2025-11-17 PHASE2
NCT07155629 NOT_YET_RECRUITING
Pancreatic Cancer Resectable
Helsinki University Central Hospital
2025-09-01 PHASE3
NCT05983276 RECRUITING
Ovarian Cancer
Loyola University
2023-11-16 PHASE2
NCT07739199 NOT_YET_RECRUITING
Squamous Non-small-cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd.
2026-08 PHASE2; PHASE3
NCT06647563 NOT_YET_RECRUITING
Squamous Cell Carcinoma of Head and Neck
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
2024-11-01 PHASE3
NCT05905315 RECRUITING
Locally Advanced Vulvar Carcinoma; Squamous Cell Carcinoma of the Vulva
The Netherlands Cancer Institute
2024-01-01 PHASE2
NCT07683221 NOT_YET_RECRUITING
Pancreatic Cancer
Shandong Cancer Hospital and Institute
2026-07-15 PHASE2
NCT06953323 RECRUITING
Advanced Solid Tumor
Wigen Biomedicine Technology (Shanghai) Co., Ltd.
2025-07-10 PHASE1; PHASE2
NCT06486441 ACTIVE_NOT_RECRUITING
Endometrial Cancer
Gilead Sciences
2024-08-28 PHASE3
NCT06245889 RECRUITING
Triple Negative Breast Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2024-05-01 PHASE2
NCT07076121 ACTIVE_NOT_RECRUITING
Pancreatic Ductal Adenocarcinoma
Bristol-Myers Squibb
2025-10-23 PHASE2; PHASE3
NCT06771154 NOT_YET_RECRUITING
Recurrent/Metastatic Endometrial Cancer
Peking Union Medical College Hospital
2025-04-01 PHASE2
NCT07463313 NOT_YET_RECRUITING
Thymoma and Thymic Carcinoma
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2026-03 PHASE2; PHASE3
NCT06996782 RECRUITING
Advanced or Metastatic Non-small Cell Lung Cancer
AstraZeneca
2025-11-24 PHASE1; PHASE2
NCT07610525 NOT_YET_RECRUITING
Triple Negative Breast Cancer; Blood and Image Guided; Optimization of Neoadjuvant Therapy; Phase 2
M.D. Anderson Cancer Center
2026-11-05 PHASE2
NCT06712316 RECRUITING
Non-small Cell Lung Cancer
BioNTech SE
2025-01-07 PHASE2; PHASE3
NCT07622797 RECRUITING
Late-stage Resectable Esophageal Squamous Carcinoma
The First Affiliated Hospital of Henan University of Science and Technology
2025-11-21 PHASE2
NCT07277452 NOT_YET_RECRUITING
Pancreatic Cancer, Adult
The First Affiliated Hospital with Nanjing Medical University
2025-12-10 PHASE2
NCT07226856 RECRUITING
Metastatic Pancreatic Adenocarcinoma; Recurrent Pancreatic Adenocarcinoma; Stage IV Pancreatic Cancer AJCC v8
Mayo Clinic
2025-12-12 PHASE2
NCT06535607 RECRUITING
Sub-study 1 Cervical Cancer (Volrustomig Monotherapy); Sub-study 2 Head and Neck Squamous Cell Carcinoma (Volrustomig Monotherapy); Sub-study 3 Head and Neck Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy); Sub-study 4 Esophageal Squamous Cell Carcinoma (Volrustomig in Combination With Chemotherapy); Sub-study 5 Unresectable Pleural Mesothelioma (Volrustomig Monotherapy)
AstraZeneca
2024-08-22 PHASE2
NCT07213804 RECRUITING
Ovarian Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Neoplasm Metastasis
Eli Lilly and Company
2025-10-22 PHASE3
NCT06904378 RECRUITING
Metastatic Pancreatic Ductal Adenocarcinoma
Washington University School of Medicine
2026-03-25 PHASE1; PHASE2
NCT07784413 NOT_YET_RECRUITING
Gastric Cancer Peritoneal Metastasis (GCPM)
Zhejiang Cancer Hospital
2026-09-01 PHASE2
NCT07016399 RECRUITING
Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Triple-Negative Breast Carcinoma
Vandana Abramson
2025-09-09 PHASE2
NCT06561763 NOT_YET_RECRUITING
High Risk Locally Advanced Nasopharyngeal Carcinoma
Sun Yat-sen University
2024-08-20 PHASE3
NCT04715542 NOT_YET_RECRUITING
Chemotherapy Induced Peripheral Neuropathy (CIPN)
University of Bern
2026-08 PHASE3
NCT06204614 ENROLLING_BY_INVITATION
Muscle Invasive Bladder Urothelial Carcinoma
Brigham and Women's Hospital
2024-06-14 EARLY_PHASE1
NCT07445295 NOT_YET_RECRUITING
Metastatic Pancreatic Ductal Adenocarcinoma
Chipscreen Biosciences, Ltd.
2026-03-31 PHASE3
NCT04241276 ACTIVE_NOT_RECRUITING
Pancreatic Cancer
Queen Mary University of London
2020-04-30 PHASE2
NCT04811703 RECRUITING
Metastatic Ovarian Carcinoma; Peritoneal Carcinomatosis; Stage III Ovarian Cancer; Stage IV Ovarian Cancer; Stage III Fallopian Tube Cancer; Stage IV Fallopian Tube Cancer; Metastatic Malignant Neoplasm in the Peritoneum
Hospices Civils de Lyon
2021-07-30 PHASE1
NCT05502237 ACTIVE_NOT_RECRUITING
Non-small Cell Lung Cancer
Gilead Sciences
2022-10-12 PHASE3
NCT05365581 RECRUITING
Gastric Adenocarcinoma; Gastroesophageal Junction (GEJ) Adenocarcinoma; Pancreatic Adenocarcinoma
Astellas Pharma Global Development, Inc.
2022-06-07 PHASE1
NCT07796126 NOT_YET_RECRUITING
Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
Barbara Ann Karmanos Cancer Institute
2026-09-30 PHASE2
NCT06835400 NOT_YET_RECRUITING
Metastatic Breast Cancer
Health Hope Pharma
2025-09 PHASE3
NCT07465757 NOT_YET_RECRUITING
Small Cell Lung Cancer ( SCLC )
Puma Biotechnology, Inc.
2026-09-30 PHASE2
NCT07290140 RECRUITING
Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps
Airiver Medical, Inc.
2026-06-01
NCT07045311 RECRUITING
Triple-negative Breast Cancer
Shanghai Junshi Bioscience Co., Ltd.
2025-09-17 PHASE2
NCT05751668 SUSPENDED
Anatomic Stage IV Breast Cancer AJCC v8; Chemotherapy-Induced Peripheral Neuropathy; Metastatic Breast Carcinoma
Alliance for Clinical Trials in Oncology
2023-11-02 PHASE2
NCT05684276 ACTIVE_NOT_RECRUITING
NSCLC; Pancoast Tumor
Fundación GECP
2023-05-12 PHASE2
NCT04931342 ACTIVE_NOT_RECRUITING
Ovarian Cancer
Hoffmann-La Roche
2021-10-07 PHASE2
NCT06771622 ACTIVE_NOT_RECRUITING
Solid Cancer
FBD Biologics Limited
2025-03-13 PHASE1; PHASE2
NCT02726997 ACTIVE_NOT_RECRUITING
Stage III Fallopian Tube Cancer AJCC v7; Stage III Ovarian Cancer AJCC v6 and v7; Stage III Primary Peritoneal Cancer AJCC v7; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7
M.D. Anderson Cancer Center
2016-07-06 PHASE1; PHASE2
NCT07477743 RECRUITING
Advanced Solid Tumor Cancer
HC Biopharma Inc.
2026-03-17 PHASE1
NCT07401654 NOT_YET_RECRUITING
Ovarian Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2026-01-31 PHASE2
NCT07244978 NOT_YET_RECRUITING
Esophageal Squamous Cell Carcinoma; Neoadjuvant Therapy
Second Affiliated Hospital, Zhejiang University, School of Medicine
2026-06-01 PHASE2
NCT06692491 NOT_YET_RECRUITING
Rare Tumour
Peking University Shenzhen Hospital
2025-01-01 PHASE2
NCT06711094 NOT_YET_RECRUITING
HR+/HER2- Advanced Breast Cancer
Fujian Medical University
2025-01-01
NCT06764355 RECRUITING
ESCC; Total Neoadjuvant Treatment; Pathological Complete Response
National Taiwan University Hospital
2025-07-23 PHASE2
NCT07481058 RECRUITING
Esophageal Squamous Cell Carcinoma (ESCC)
Beijing Konruns Pharmaceutical Co., Ltd.
2025-12-12 PHASE2
NCT07392346 RECRUITING
Gastric Cancer Adenocarcinoma Metastatic
Dai, Guanghai
2025-12-01 PHASE2
NCT05256225 RECRUITING
Endometrial Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Dedifferentiated Carcinoma; Endometrial Endometrioid Adenocarcinoma; Endometrial Mixed Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Undifferentiated Carcinoma; Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor
National Cancer Institute (NCI)
2022-11-16 PHASE3
NCT05296798 ACTIVE_NOT_RECRUITING
Locally Advanced or Metastatic Breast Cancer
Hoffmann-La Roche
2022-07-18 PHASE3
NCT05487391 RECRUITING
Carcinoma, Non-Small-Cell Lung
Qilu Pharmaceutical Co., Ltd.
2022-12-08 PHASE3
NCT06483555 RECRUITING
Pancreatic Adenocarcinoma; Metastatic Pancreatic Cancer; Basal Cell Neoplasm
UNC Lineberger Comprehensive Cancer Center
2025-02-06 PHASE1; PHASE2
NCT06962267 RECRUITING
Pancreatic Cancer
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd.
2025-04-18 PHASE2
NCT07739485 RECRUITING
Triple -Negative Breast Cancer
Liu Shu
2026-07-30 PHASE1; PHASE2
NCT07662746 RECRUITING
Head and Neck Cancer
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
2026-07-01 PHASE2
NCT06752811 RECRUITING
Pancreatic Cancer Metastatic
Shanghai Yizhong Pharmaceutical Co., Ltd.
2025-02-05 PHASE3
NCT06942234 RECRUITING
Inoperable Locally Advanced HER2-Negative Breast Cancer; Metastatic HER2-Negative Breast Cancer
Jiangsu Alphamab Biopharmaceuticals Co., Ltd
2025-06-01 PHASE1; PHASE2
NCT05420454 RECRUITING
Breast Cancer
Second Affiliated Hospital, Zhejiang University, School of Medicine
2022-07-10 PHASE4
NCT06415318 RECRUITING
Penile Cancer
Sun Yat-sen University
2024-05-31 PHASE2
NCT07669740 NOT_YET_RECRUITING
Gastric Cancer (Diagnosis)
The First Affiliated Hospital with Nanjing Medical University
2026-07-01 PHASE2
NCT02297217 RECRUITING
Esophageal Cancer
AHS Cancer Control Alberta
2019-11-21 PHASE2
NCT06407310 NOT_YET_RECRUITING
Triple Negative Breast Cancer
Tel Aviv Medical Center
2024-07-01 PHASE2
NCT06494514 RECRUITING
Locally Advanced Pancreatic Cancer
Du Juan
2024-04-01
NCT07549958 RECRUITING
Pancreatic Cancer; Pancreatic Cancer Metastatic
University of California, Irvine
2026-03-24 PHASE1
NCT04158635 SUSPENDED
Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Carcinoma
City of Hope Medical Center
2021-09-01 PHASE1
NCT06727565 ACTIVE_NOT_RECRUITING
Head and Neck Squamous Cell Carcinoma
Gilead Sciences
2025-02-18 PHASE2
NCT05497778 ACTIVE_NOT_RECRUITING
Pancreas Cancer
M.D. Anderson Cancer Center
2022-10-21 PHASE1
NCT06770452 RECRUITING
Metastatic Pancreatic Carcinoma
Zhejiang University
2025-03-25 PHASE2
NCT05325632 RECRUITING
HER2-positive Breast Cancer
H. Lee Moffitt Cancer Center and Research Institute
2021-10-28 PHASE2
NCT05969171 RECRUITING
Pancreatic Cancer Metastatic
Fudan University
2023-12-05 PHASE2
NCT04460352 RECRUITING
Esophageal Squamous Cell Carcinoma
Karolinska University Hospital
2020-11-27 PHASE3
NCT06751277 NOT_YET_RECRUITING
Recurrent or Metastatic Endometrial Cancer
xiang yang
2025-02-01 PHASE2
NCT06684327 RECRUITING
Paget Disease, Extramammary; Rhabdomyosarcoma; Testicular Cancer; Penile Cancer; Urachal Cancer
Fudan University
2024-11-30 PHASE2
NCT07245797 NOT_YET_RECRUITING
Breast Cancer
Zhimin Shao
2025-12-15 PHASE2
NCT06400849 RECRUITING
Non-metastatic Breast Cancer
Centre Antoine Lacassagne
2024-04-04
NCT06943820 RECRUITING
Non-small Cell Lung Cancer Stage IIIB/IV; Head and Neck Squamous Cell Carcinoma (HNSCC); Colorectal Adenocarcinoma; Advanced Solid Tumors
Akeso
2025-05-21 PHASE1; PHASE2
NCT06202261 RECRUITING
Metastatic Breast Cancer; Recurrent Breast Cancer; Advanced Malignancies
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2023-04-13 PHASE1; PHASE2
NCT07580833 NOT_YET_RECRUITING
Metastatic Breast Cancer
Health Hope Pharma
2026-05 PHASE1
NCT02962063 ACTIVE_NOT_RECRUITING
Esophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma
Memorial Sloan Kettering Cancer Center
2016-11 PHASE1; PHASE2
NCT07504770 NOT_YET_RECRUITING
Paclitaxel-Induced Peripheral Neuropathy; Breast Cancer; Surgical Glove
Necmettin Erbakan University
2026-03-26
NCT06447662 ACTIVE_NOT_RECRUITING
Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung
Pfizer
2024-06-27 PHASE1
NCT05451043 RECRUITING
Pancreatic Cancer; Hepatocellular Cancer; Biliary Tract Cancer; Cholangiocarcinoma
AHS Cancer Control Alberta
2023-07-05 PHASE2
NCT05116462 ACTIVE_NOT_RECRUITING
Non-Small Cell Lung Cancer
Innovent Biologics (Suzhou) Co. Ltd.
2024-03-15 PHASE3
NCT03085056 ACTIVE_NOT_RECRUITING
Anaplastic Thyroid Cancer
Memorial Sloan Kettering Cancer Center
2017-03-15 EARLY_PHASE1
NCT05107674 RECRUITING
Ovarian Cancer, Epithelial; Gastric Cancer; GastroEsophageal Junction (GEJ) Cancer; Head and Neck Squamous Cell Carcinoma; Metastatic or Unresectable Melanoma; Non-small Cell Lung Cancer (NSCLC); Metastatic Castration-resistant Prostate Cancer (mCRPC); Malignant Pleural Mesothelioma (MPM); Triple Negative Breast Cancer (TNBC); Metastatic Urothelial Carcinoma; Cervical Cancer; Diffuse Large B Cell Lymphoma (DLBCL); Richter Transformation; Microsatellite Stable Colorectal Carcinoma
Nurix Therapeutics, Inc.
2021-09-29 PHASE1
NCT05498896 ACTIVE_NOT_RECRUITING
Triple Negative Breast Cancer
Queen Mary University of London
2018-12-19 PHASE2
NCT07125391 RECRUITING
Ovarian Cancer
Bai-Rong Xia
2025-06-20 PHASE2
NCT06241469 NOT_YET_RECRUITING
Gastric Cancer; GastroEsophageal Cancer; Adenocarcinoma
Wu Jun
2024-02-03 PHASE2
NCT04304248 UNKNOWN
Non Small Cell Lung Cancer
Hao Long
2019-08-01 PHASE2
NCT06853678 RECRUITING
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Tianjin Medical University Cancer Institute and Hospital
2025-02-28
NCT07699185 RECRUITING
Esophageal Squamous Cell Carcinoma
Tongji Hospital
2024-01-29 PHASE2
NCT06690476 RECRUITING
Esophageal Squamous Cell Carcinoma
Peking University
2024-10-10 EARLY_PHASE1
NCT06162468 NOT_YET_RECRUITING
Intraductal Papillary Mucinous Neoplasm of Pancreas
University of Auckland, New Zealand
2025-05-31
NCT05298423 COMPLETED
Carcinoma, Non-Small-Cell Lung
Merck Sharp & Dohme LLC
2022-05-03 PHASE3
NCT04862650 ACTIVE_NOT_RECRUITING
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Metastatic Head and Neck Squamous Cell Carcinoma; Metastatic Hypopharyngeal Squamous Cell Carcinoma; Metastatic Laryngeal Squamous Cell Carcinoma; Metastatic Oral Cavity Squamous Cell Carcinoma; Metastatic Oropharyngeal Squamous Cell Carcinoma; Pathologic Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8; Recurrent Head and Neck Squamous Cell Carcinoma; Recurrent Hypopharyngeal Squamous Cell Carcinoma; Recurrent Laryngeal Squamous Cell Carcinoma; Recurrent Oral Cavity Squamous Cell Carcinoma; Recurrent Oropharyngeal Squamous Cell Carcinoma; Squamous Cell Carcinoma of Unknown Primary; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Oral Cavity Cancer AJCC v8; Stage IVA Hypopharyngeal Carcinoma AJCC v8; Stage IVA Laryngeal Cancer AJCC v8; Stage IVA Lip and Oral Cavity Cancer AJCC v8; Stage IVB Hypopharyngeal Carcinoma AJCC v8; Stage IVB Laryngeal Cancer AJCC v8; Stage IVB Lip and Oral Cavity Cancer AJCC v8; Stage IVC Hypopharyngeal Carcinoma AJCC v8; Stage IVC Laryngeal Cancer AJCC v8; Stage IVC Lip and Oral Cavity Cancer AJCC v8
Marcelo Bonomi
2021-11-30 PHASE2
NCT06143748 ACTIVE_NOT_RECRUITING
Esophagus Cancer
Sun Yat-sen University
2024-03-02 PHASE2
NCT06454435 NOT_YET_RECRUITING
Gastric Cancer; Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma
Tianjin Medical University Cancer Institute and Hospital
2024-06 PHASE2
NCT04015778 ACTIVE_NOT_RECRUITING
Non Small Cell Lung Cancer
Guangdong Association of Clinical Trials
2019-08-08 PHASE2
NCT06398587 WITHDRAWN
Locally Advanced Pancreatic Ductal Adenocarcinoma; Metastatic Pancreatic Ductal Adenocarcinoma; Stage II Pancreatic Cancer AJCC v8; Stage III Pancreatic Cancer AJCC v8; Stage IV Pancreatic Cancer AJCC v8; Unresectable Pancreatic Adenocarcinoma
OHSU Knight Cancer Institute
2024-08-01 PHASE2
NCT04481204 WITHDRAWN
Borderline Resectable Pancreatic Adenocarcinoma; Locally Advanced Pancreatic Ductal Adenocarcinoma; Resectable Pancreatic Ductal Adenocarcinoma
M.D. Anderson Cancer Center
2023-04-18 PHASE2
NCT04638582 TERMINATED
Lung Cancer, Nonsmall Cell
McGill University Health Centre/Research Institute of the McGill University Health Centre
2022-08-28 PHASE2
NCT05207709 TERMINATED
Metastatic Breast Cancer
SOLTI Breast Cancer Research Group
2022-03-28 PHASE3
NCT05743270 WITHDRAWN
Squamous Cell Carcinoma of Head and Neck; Locally Advanced Head and Neck Squamous Cell Carcinoma; Recurrent Head and Neck Squamous Cell Carcinoma
Replimune, Inc.
2024-01-30 PHASE2
NCT05978050 UNKNOWN
Gastric or Esophagogastric Junction Adenocarcinoma
Biotech Pharmaceutical Co., Ltd.
2024-08-01 PHASE3
NCT05117476 ACTIVE_NOT_RECRUITING
Advanced Solid Tumor; NSCLC
Cullinan Therapeutics Inc.
2021-10-29 PHASE1
NCT04872985 ACTIVE_NOT_RECRUITING
Breast Cancer; Hormone-receptor Positive Breast Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2021-04-20 PHASE2
NCT05501665 RECRUITING
Lung Non-Small Cell Carcinoma; Stage IV Lung Cancer AJCC v8; Stage III Lung Cancer
Vanderbilt-Ingram Cancer Center
2023-05-09 PHASE1; PHASE2
NCT05241249 RECRUITING
Pancreas Cancer
Susan E. Bates
2022-02-01 PHASE2
NCT06140576 NOT_YET_RECRUITING
Breast Neoplasms
Zhejiang Cancer Hospital
2023-11-30 PHASE1; PHASE2
NCT05640830 RECRUITING
HER2-positive Advanced Gastric Cancer
Kangbuk Samsung Hospital
2023-01-01 PHASE1; PHASE2
NCT07117435 RECRUITING
Colorectal Liver Metastases; First-line Treatment
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
2025-05-13 PHASE1
NCT06867562 NOT_YET_RECRUITING
Platinum-Resistant Primary Peritoneal Carcinoma; Platinum Resistant High Grade Epithelial Ovarian Cancer; Platinum Resistant High Grade Serous Ovarian Cancer
Jina Pharmaceuticals Inc.
2025-04 PHASE3
NCT02705196 COMPLETED
Pancreatic Cancer
Lokon Pharma AB
2016-11 PHASE1; PHASE2
NCT06100497 RECRUITING
Head and Neck Squamous Cell Carcinoma
Beijing Tongren Hospital
2023-10-01 PHASE2
NCT04649385 COMPLETED
Advanced Solid Tumor
BeiGene
2021-03-04 PHASE1
NCT06679387 RECRUITING
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Ain Shams University
2024-10-30 PHASE2
NCT05754853 RECRUITING
Advanced or Metastatic Urothelium Cancer
Shanghai Miracogen Inc.
2023-04-06 PHASE3
NCT06786026 RECRUITING
TNBC, Triple Negative Breast Cancer
Fudan University
2024-10-09 PHASE2
NCT06588335 NOT_YET_RECRUITING
Esophageal Squamous Cell Carcinoma
Henan Provincial People's Hospital
2024-09-30 PHASE2
NCT05374512 ACTIVE_NOT_RECRUITING
Breast Cancer
AstraZeneca
2022-05-16 PHASE3
NCT06018883 UNKNOWN
Metastatic Pancreatic Adenocarcinoma
Fudan University
2023-08-20 PHASE3
NCT06486545 UNKNOWN
Advanced Gastric Cancer
Hunan Cancer Hospital
2024-08-25
NCT06048926 ENROLLING_BY_INVITATION
Esophageal Squamous Cell Carcinoma
The First Affiliated Hospital with Nanjing Medical University
2022-07-30
NCT05185869 UNKNOWN
Pancreatic Cancer
Ruijin Hospital
2022-01 PHASE2
NCT03918278 COMPLETED
Neoplasms
Merck Sharp & Dohme LLC
2019-06-19 PHASE1
NCT04046575 ACTIVE_NOT_RECRUITING
Esophagus Cancer; Esophageal Cancer; Cancer of the Esophagus
Washington University School of Medicine
2019-11-07 PHASE1
NCT02520154 COMPLETED
Stage III Fallopian Tube Cancer AJCC v7; Stage III Ovarian Cancer AJCC v6 and v7; Stage III Primary Peritoneal Cancer AJCC v7; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7
M.D. Anderson Cancer Center
2016-07-05 PHASE2
NCT05908747 COMPLETED
Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
2023-05-31 PHASE2
NCT06472037 UNKNOWN
Locally Advanced Pancreatic Ductal Adenocarcinoma
Tianjin Medical University Cancer Institute and Hospital
2024-07-01 PHASE2
NCT02429687 RECRUITING
Ovarian Germ Cell Cancer; Ovarian Neoplasms; Ovarian Cancer
Beihua Kong
2015-04 PHASE3
NCT05312372 Withdrawn
Esophageal Squamous Cell Carcinoma
Institut de Recherches Internationales Servier|ADIR a Servier Group company|Servier
2025-05 Phase 1|Phase 2
NCT03088540 COMPLETED
Carcinoma,Non-Small-Cell Lung; Lung Carcinomas, Non-Small-Cell; Non-small-cell Lung Carcinoma; Nonsmall Cell Lung Cancer
Regeneron Pharmaceuticals
2017-05-29 PHASE3
NCT05673811 COMPLETED
Pancreatic Adenocarcinoma; Metastatic
Theriva Biologics SL
2023-01-10 PHASE2
NCT05257408 ACTIVE_NOT_RECRUITING
Ovarian Neoplasm; Fallopian Tube Neoplasms; Peritoneal Neoplasms
Corcept Therapeutics
2022-06-29 PHASE3
NCT04832854 TERMINATED
Non-Small Cell Lung Cancer (NSCLC)
Hoffmann-La Roche
2021-04-23 PHASE2
NCT04222972 TERMINATED
RET-fusion Non Small Cell Lung Cancer; Lung Neoplasm; Carcinoma, Non-Small-Cell Lung; Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Disease; Carcinoma, Bronchogenic; Bronchial Diseases; Head and Neck Neoplasms; Adenocarcinoma; Carcinoma; Neoplasms by Histologic Type; Neoplasms, Germ Cell and Embryonal; Neoplasms, Nerve Tissue
Hoffmann-La Roche
2020-07-24 PHASE3
NCT03598426 COMPLETED
Hypersensitivity Reactions
Loma Linda University
2018-08-08 PHASE3
NCT05178628 UNKNOWN
Pancreatic Cancer; Thromboembolism
Michalis Karamouzis
2022-02-10 PHASE3
NCT05291910 UNKNOWN
Breast Cancer
Chinese Academy of Medical Sciences
2022-03-12 PHASE4
NCT04547907 RECRUITING
Breast Cancer,HER2-positive
Henan Cancer Hospital
2020-09-18 PHASE3
NCT04447092 UNKNOWN
Pancreatic Cancer; Chemotherapy Effect
Seoul National University Hospital
2020-07-01 PHASE2
NCT06016413 NOT_YET_RECRUITING
Head and Neck Squamous Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2023-09-01 PHASE2
NCT06237257 UNKNOWN
Locally Advanced Cervical Cancer
Shanghai Shengdi Pharmaceutical Co., Ltd
2024-03-20 PHASE2
NCT04876313 UNKNOWN
Muscle-Invasive Bladder Carcinoma
IRCCS San Raffaele
2022-01-27 PHASE2
NCT01706120 UNKNOWN
Ovarian Cancer
National Cancer Institute, Naples
2012-10 PHASE4
NCT02794571 COMPLETED
Advanced/Metastatic Tumors
Genentech, Inc.
2016-05-23 PHASE1
NCT03750669 COMPLETED
Pancreatic Adenocarcinoma Resectable; Neoadjuvant Chemotherapy
Second Affiliated Hospital, Zhejiang University, School of Medicine
2018-10-20 PHASE3
NCT05900921 UNKNOWN
Advanced Squamous Non-Small-Cell Lung Cancer
Sichuan University
2023-07-01 PHASE2
NCT04958785 TERMINATED
Triple-Negative Breast Cancer
Gilead Sciences
2021-12-14 PHASE2
NCT02584478 UNKNOWN
Endometrial Carcinoma; Ovarian Carcinoma; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma; Cervical Carcinoma
Advenchen Laboratories, LLC
2015-12 PHASE3
NCT03107182 COMPLETED
HPV-Related Squamous Cell Carcinoma; HNSCC
University of Chicago
2017-06-27 PHASE2
NCT04715542 Not yet recruiting
Chemotherapy Induced Peripheral Neuropathy (CIPN)
University of Bern|Insel Gruppe AG University Hospital Bern|Hospital of Thun|Tumor- und Brustzentrum ZeTuP St.Gallen|Gesundheitszentrum Fricktal AG|Kantonsspital Winterthur KSW|Kantonsspital Graubünden|Kantonsspital Aarau
2024-08 Phase 3
NCT05715840 UNKNOWN
Recurrent, or Metastatic Cervical Cancer With PD-L1 Positive (CPS≥1)
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
2023-01-31 PHASE3
NCT04554524 UNKNOWN
Thymoma and Thymic Carcinoma
Tang-Du Hospital
2020-08-27 PHASE4
NCT03393884 ACTIVE_NOT_RECRUITING
Epithelial Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer
Imunon
2018-09-05 PHASE1; PHASE2
NCT05761470 RECRUITING
Her-2 Negative Breast Cancer; HRR Gene Mutation
Ying Lin
2022-05-06 PHASE2
NCT04967417 COMPLETED
Non-small Cell Lung Cancer
Samsung Medical Center
2022-05-26 PHASE2
NCT04643405 TERMINATED
Advanced Pancreatic Cancer
Ascentage Pharma Group Inc.
2021-03-17 PHASE1; PHASE2
NCT05613088 COMPLETED
Neoplasms, Ovarian
Bristol-Myers Squibb
2023-02-01 PHASE2
NCT04289792 UNKNOWN
Pancreatic Neoplasms
Fujian Medical University Union Hospital
2020-05-09 PHASE2
NCT06387901 Not yet recruiting
Breast Cancer|Paclitaxel Adverse Reaction|Chemotherapeutic Toxicity|Chemotherapeutic Agent Toxicity|Body Weight|Physical Inactivity
Universitair Ziekenhuis Brussel|Vrije Universiteit Brussel|University Ghent
2024-05-06 --
NCT05826015 Not yet recruiting
Recurrent High Grade Uterine Cancer
Washington University School of Medicine|National Cancer Institute (NCI)|Aravive Inc.
2024-05-31 Phase 1
NCT05450042 UNKNOWN
Peripheral Arterial Disease; Flow-mediated Dilation; Drug Eluting Balloon; Infrainguinal Peripheral Arterial Disease
University Hospital, Essen
2022-04-06
NCT05695313 Recruiting
Breast Cancer
Centre Georges Francois Leclerc
2024-04-12 Phase 2
NCT05367206 RECRUITING
Cervical Cancer; Neoadjuvant Chemotherapy; Bulky Neoplasm
Sun Yat-sen University
2022-03-14 PHASE3
NCT05872412 UNKNOWN
Triple Negative Breast Cancer
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
2023-06-01 PHASE2
NCT05159050 TERMINATED
Peritoneal Carcinomatosis
Carlos Chan
2022-04-26 PHASE1
NCT05947201 UNKNOWN
The Efficacy and Safety of Therapy Efficacy for Locally Advanced ESCC
Weijia Fang, MD
2023-05-08 PHASE2
NCT05611879 UNKNOWN
NSCLC, Stage III
Beijing Tsinghua Chang Gung Hospital
2023-03-12 PHASE2
NCT01847326 COMPLETED
Recurrent Salivary Gland Cancer; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Squamous Cell Carcinoma of the Nasopharynx; Recurrent Squamous Cell Carcinoma of the Oropharynx; Recurrent Squamous Cell Carcinoma of the Paranasal Sinus and Nasal Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Salivary Gland Squamous Cell Carcinoma; Tongue Cancer
University of Chicago
2013-03-26 PHASE1
NCT04077255 UNKNOWN
Adenocarcinoma of the Stomach
National Cancer Center, Korea
2019-09-01 PHASE2
NCT05386888 COMPLETED
NSCLC, Stage III
Genfleet Therapeutics (Shanghai) Inc.
2022-09-09 PHASE2
NCT00980954 COMPLETED
Cervical Cancer
Radiation Therapy Oncology Group
2009-09 PHASE3
NCT04632992 COMPLETED
Advanced Unresectable or Metastatic Solid Malignancy
Genentech, Inc.
2021-01-13 PHASE2
NCT02689427 COMPLETED
Invasive Breast Carcinoma; Stage I Breast Cancer AJCC v7; Stage IA Breast Cancer AJCC v7; Stage IB Breast Cancer AJCC v7; Stage II Breast Cancer AJCC v6 and v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Triple-Negative Breast Carcinoma
M.D. Anderson Cancer Center
2016-09-22 PHASE2
NCT02501954 COMPLETED
Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Stage IIIA Uterine Corpus Cancer; Stage IIIB Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer
Women's Cancer Care Associates, LLC
2015-03 PHASE3
NCT05669807 UNKNOWN
Second Line Treatment of Gastric Cancer
Zhejiang Cancer Hospital
2022-12 PHASE2
NCT02436993 ACTIVE_NOT_RECRUITING
Breast Carcinoma
University of California, Irvine
2015-04 PHASE2
NCT04865289 COMPLETED
Endometrial Neoplasms
Merck Sharp & Dohme LLC
2019-10-22 PHASE3
NCT05552807 UNKNOWN
Head and Neck Squamous Carcinoma
Sinocelltech Ltd.
2022-06-15 PHASE1
NCT03141359 ACTIVE_NOT_RECRUITING
Lung Cancer Stage II; Lung Cancer Stage III; Non Small Cell Lung Cancer
Wake Forest University Health Sciences
2017-05-12 PHASE2
NCT04770272 TERMINATED
Triple-negative Breast Cancer
Palleos Healthcare GmbH
2021-03-01 PHASE2
NCT04814485 UNKNOWN
Pancreatic Cancer
Tianjin Medical University Cancer Institute and Hospital
2021-04-22 PHASE2
NCT05449483 UNKNOWN
Esophageal Squamous Cell Carcinoma by AJCC V8 Stage; Unresectable
Tianjin Medical University Cancer Institute and Hospital
2022-05-11 PHASE2
NCT05410847 UNKNOWN
Gastric Cancer
Hebei Medical University
2022-06-30 PHASE2
NCT03815461 UNKNOWN
Locally Advanced Pancreatic Cancer
Chinese Academy of Medical Sciences
2019-02-01 PHASE2
NCT04840290 UNKNOWN
Non Small Cell Lung Cancer
Tang-Du Hospital
2019-06-01 PHASE3
NCT04310943 COMPLETED
Lung Adenocarcinoma Stage IV
Zhou Chengzhi
2021-03-01 PHASE2
NCT05138159 UNKNOWN
Metastatic Pancreatic Cancer
Fudan University
2021-12-01 PHASE2
NCT03003546 COMPLETED
Recurrent Aggressive Non-Hodgkin Lymphoma; Recurrent B-Cell Non-Hodgkin Lymphoma; Recurrent Small Lymphocytic Lymphoma; Refractory Aggressive Non-Hodgkin Lymphoma; Refractory B-Cell Non-Hodgkin Lymphoma; Refractory Small Lymphocytic Lymphoma
Mayo Clinic
2019-04-25 PHASE1
NCT04038489 WITHDRAWN
Breast Cancer; Estrogen Receptor-positive Breast Cancer
University of Virginia
2019-10-18 PHASE2
NCT05322499 UNKNOWN
Stage IV Esophagus Squamous Cell Carcinoma
Zhejiang Cancer Hospital
2022-04-15 PHASE2
NCT04079192 UNKNOWN
Coronary Artery Disease; In-Stent Restenosis
Biosensors Europe SA
2020-08-07
NCT00003927 COMPLETED
Breast Cancer
City of Hope Medical Center
1999-05-18 PHASE1
NCT04209855 COMPLETED
Epithelial Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer
AbbVie
2019-12-31 PHASE3
NCT04846634 NOT_YET_RECRUITING
Resectable Locally Advanced Non-small Cell Lung Cancer
Tianjin Medical University Cancer Institute and Hospital
2021-08 PHASE2
NCT05566457 UNKNOWN
Breast Cancer
Chinese Academy of Medical Sciences
2020-01-01 PHASE2
NCT04722718 UNKNOWN
Breast Cancer
Jiuda Zhao
2021-02-01 PHASE2
NCT05207904 UNKNOWN
Non-Small Cell Squamous Lung Cancer; Brain Metastases
Sun Yat-sen University
2021-06-17 PHASE2
NCT02390427 COMPLETED
Metastatic Breast Cancer; Recurrent Breast Cancer
Otto Metzger, MD
2015-04-20 PHASE1
NCT03666832 UNKNOWN
Metastatic Pancreatic Cancer
Joon Oh Park
2019-06-17 PHASE1; PHASE2
NCT02629718 UNKNOWN
PFS; OS; Quality of Life
Sun Yat-sen University
2015-12 PHASE3
NCT04581343 COMPLETED
Metastatic Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer Action Network
2020-11-02 PHASE1
NCT05298696 COMPLETED
Peripheral Neuropathy; Breast Cancer
Mansoura University
2022-03-28 PHASE1; PHASE2
NCT03535727 COMPLETED
Adenocarcinoma; Pancreatic Neoplasms; Neoplasm, Glandular; Neoplasms; Neoplasms Pancreatic; Digestive System Neoplasm; Endocrine Gland Neoplasms; Digestive System Disease; Pancreatic Diseases; Endocrine System Diseases
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2018-06-21 PHASE1; PHASE2
NCT04422392 TERMINATED
Non Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China
2020-07-13 PHASE2
NCT02426281 COMPLETED
Pancreatic Ductal Adenocarcinoma
Samsung Medical Center
2015-06-04 PHASE2
NCT03928314 TERMINATED
Solid Tumor
ORIC Pharmaceuticals
2019-05-02 PHASE1
NCT03965689 ACTIVE_NOT_RECRUITING
Metastatic Lung Non-Small Cell Squamous Carcinoma; Metastatic Lung Non-Squamous Non-Small Cell Carcinoma; Stage IIIB Lung Cancer AJCC v8; Stage IV Lung Cancer AJCC v8; Stage IVA Lung Cancer AJCC v8; Stage IVB Lung Cancer AJCC v8; Unresectable Lung Non-Small Cell Carcinoma; Unresectable Lung Non-Squamous Non-Small Cell Carcinoma
National Cancer Institute (NCI)
2020-04-16 PHASE2
NCT04551950 COMPLETED
Cervical Cancer
EMD Serono Research & Development Institute, Inc.
2020-10-19 PHASE1
NCT04825938 NOT_YET_RECRUITING
Salivary Gland Malignant Neoplasms; Salivary Gland Tumors
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
2021-04-30 PHASE2
NCT04390958 UNKNOWN
Esophageal Squamous Cell Carcinoma
Chinese Academy of Medical Sciences
2020-05-15 PHASE2
NCT04659499 UNKNOWN
Early Breast Cancer
Peking Union Medical College Hospital
2021-01 PHASE2
NCT04222790 COMPLETED
Early Breast Cancer
Henan Cancer Hospital
2020-08-28 PHASE2
NCT03519308 TERMINATED
Pancreatic Cancer
Abramson Cancer Center at Penn Medicine
2020-07-29 EARLY_PHASE1
NCT03539328 UNKNOWN
Ovarian Cancer
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
2018-06 PHASE2
NCT04203485 UNKNOWN
PD-L1 Positive Non-small Cell Lung Cancer
Jiangsu HengRui Medicine Co., Ltd.
2020-06-15 PHASE3
NCT04063683 UNKNOWN
Esophageal Squamous Cell Carcinoma
Henan Cancer Hospital
2019-10-07 PHASE2
NCT02564146 COMPLETED
Metastatic Pancreatic Cancer; Adenocarcinoma of the Pancreas
AIO-Studien-gGmbH
2016-12 PHASE2
NCT04632342 UNKNOWN
Radiation Pneumonitis; Lung Cancer
Hanlim Pharm. Co., Ltd.
2020-11 PHASE2
NCT02229149 TERMINATED
Breast Neoplasms; Malignant Tumor of the Breast
US Oncology Research
2014-12 PHASE2
NCT04001569 UNKNOWN
Solid Tumor; Stomach Cancer
Seoul National University Bundang Hospital
2019-05-14 PHASE1; PHASE2
NCT02420314 COMPLETED
Carcinoma, Non-Small-Cell Lung
Joseph J. Cullen, MD, FACS
2015-04 PHASE2
NCT02617849 UNKNOWN
Metastatic Malignant Melanoma
Wilson Miller
2016-05-19 PHASE2
NCT02684461 COMPLETED
Non Small Cell Lung Cancer
UNC Lineberger Comprehensive Cancer Center
2016-09-13 PHASE2
NCT02954055 COMPLETED
Breast Cancer
ETOP IBCSG Partners Foundation
2017-09-13 PHASE2
NCT03703063 UNKNOWN
Pancreatic Adenocarcinoma
Benaroya Research Institute
2018-09-17 PHASE1
NCT01779050 TERMINATED
Breast Neoplasms
Washington University School of Medicine
2013-12-19 PHASE2
NCT04210037 TERMINATED
Small Cell Lung Cancer
Ascentage Pharma Group Inc.
2020-08-20 PHASE1; PHASE2
NCT04737967 UNKNOWN
Oncology Pain; Chemotherapy-induced Peripheral Neuropathy
Mendel AI
2021-02-15 PHASE2; PHASE3
NCT04108013 UNKNOWN
Lung Cancer Stage II; PD-1 Antibody; Non-small Cell Lung Cancer
Xuanwu Hospital, Beijing
2019-10-08 PHASE2
NCT04073537 UNKNOWN
Squamous Non-small Cell Lung Cancer
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2019-10-31 PHASE3
NCT02822157 UNKNOWN
Ovarian Epithelial Cancer
Universitaire Ziekenhuizen KU Leuven
2016-08 PHASE2
NCT03019588 TERMINATED
Gastric Neoplasms; Gastroesophageal Junction Adenocarcinoma
Merck Sharp & Dohme LLC
2017-02-16 PHASE3
NCT02550327 COMPLETED
Pancreatic Adenocarcinoma
Baylor Research Institute
2016-01 EARLY_PHASE1
NCT01325441 COMPLETED
Cancer
Sumitomo Pharma America, Inc.
2011-04 PHASE1; PHASE2
NCT03987867 UNKNOWN
Non-small Cell Lung Cancer; First-line Treatment
Tianjin Medical University Cancer Institute and Hospital
2019-06-01 PHASE1
NCT04299880 COMPLETED
Oncology
Sumitomo Pharma America, Inc.
2020-02-24 PHASE1
NCT04473716 COMPLETED
Oral Cancer; Induction Chemotherapy; Programmed Cell Death 1 Inhibitor; Inductive Therapy
Shanghai Jiao Tong University School of Medicine
2020-07-30 PHASE1
NCT03314740 COMPLETED
Ovarian Neoplasms
Mario Negri Institute for Pharmacological Research
2017-06-12 PHASE2
NCT03655080 TERMINATED
Cord Compression
Washington University School of Medicine
2019-01-09 PHASE2
NCT03214250 COMPLETED
Metastatic Pancreatic Adenocarcinoma
Parker Institute for Cancer Immunotherapy
2017-07-21 PHASE1; PHASE2
NCT04054362 COMPLETED
Pancreatic Cancer
Barts & The London NHS Trust
2018-11-29 PHASE2
NCT03086369 COMPLETED
Metastatic Pancreatic Cancer
Eli Lilly and Company
2017-06-22 PHASE1; PHASE2
NCT03901118 COMPLETED
Ovarian Cancer
Chipscreen Biosciences, Ltd.
2019-07-01 PHASE2
NCT04239001 UNKNOWN
Advanced Pancreatic Cancer
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
2020-02
NCT03395080 COMPLETED
Endometrial Cancer; Uterine Cancer; Ovarian Cancer; Carcinosarcoma
Leap Therapeutics, Inc.
2018-03-05 PHASE2
NCT02392637 COMPLETED
Stage III Intrahepatic Cholangiocarcinoma AJCC v7; Stage IIIA Gallbladder Cancer AJCC v7; Stage IIIB Gallbladder Cancer AJCC v7; Stage IVA Gallbladder Cancer AJCC v7; Stage IVA Intrahepatic Cholangiocarcinoma AJCC v7; Stage IVB Gallbladder Cancer AJCC v7; Stage IVB Intrahepatic Cholangiocarcinoma AJCC v7; Unresectable Extrahepatic Bile Duct Carcinoma; Unresectable Gallbladder Carcinoma
M.D. Anderson Cancer Center
2015-04-02 PHASE2
NCT03636308 UNKNOWN
Pancreatic Cancer
Peking University
2018-07-17 PHASE2
NCT03394885 COMPLETED
Ovarian Cancer; Ovarian Neoplasms
Duke University
2018-06-19 PHASE1; PHASE2
NCT03912402 UNKNOWN
Cervical Cancer; Cervical Cancer Metastatic; Cervical Cancer Recurrent
Biocad
2018-12-25 PHASE2
NCT03517176 COMPLETED
Pancreatic Cancer; Pancreatic Ductal Adenocarcinoma
Lisata Therapeutics, Inc.
2018-07-31 PHASE1
NCT02913274 TERMINATED
Stenosis of Arteriovenous Dialysis Fistula
Rennes University Hospital
2017-03-20
NCT03117049 COMPLETED
Non-Small Cell Lung Cancer
Ono Pharmaceutical Co., Ltd.
2017-06-13 PHASE3
NCT02628132 COMPLETED
Breast Cancer
King Faisal Specialist Hospital & Research Center
2016-11 PHASE1; PHASE2
NCT03777579 SUSPENDED
Triple Negative Breast Cancer
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
2018-12-21 PHASE3
NCT03057600 COMPLETED
Triple Negative Breast Cancer; TNBC - Triple-Negative Breast Cancer
Calithera Biosciences, Inc
2017-05-01 PHASE2
NCT02427841 COMPLETED
Pancreatic Adenocarcinoma; Resectable Pancreatic Carcinoma
OHSU Knight Cancer Institute
2016-01-21 PHASE2
NCT01270724 COMPLETED
CNS Germ Cell Tumor
Nationwide Children's Hospital
2010-08 PHASE2
NCT02308553 COMPLETED
Cutaneous Malignant Melanoma
Prof. Dr. med. Dirk Schadendorf
2015-03-17 PHASE1; PHASE2
NCT02551185 COMPLETED
Advanced Solid Tumors
Celgene
2015-12-22 PHASE1
NCT01572038 COMPLETED
Breast Neoplasms
Hoffmann-La Roche
2012-06-01 PHASE3
NCT02681432 UNKNOWN
Epithelial Ovarian Cancer
PEDRO VILLAREJO CAMPOS
2012-01 PHASE3
NCT03625830 UNKNOWN
Small Vessel Disease
B. Braun Medical International Trading Company Ltd.
2017-12-18
NCT03493854 COMPLETED
Early Breast Cancer
Hoffmann-La Roche
2018-06-14 PHASE3
NCT02044601 WITHDRAWN
Lung Cancer
M.D. Anderson Cancer Center
2014-06 PHASE1; PHASE2
NCT03344172 TERMINATED
Pancreatic Cancer Resectable
Nathan Bahary, MD
2017-12-13 PHASE2
NCT02065687 UNKNOWN
Endometrial Adenocarcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Undifferentiated Carcinoma; Recurrent Uterine Corpus Carcinoma; Stage III Uterine Corpus Cancer AJCC v7; Stage IIIA Uterine Corpus Cancer AJCC v7; Stage IIIB Uterine Corpus Cancer AJCC v7; Stage IIIC Uterine Corpus Cancer AJCC v7; Stage IV Uterine Corpus Cancer AJCC v7; Stage IVA Uterine Corpus Cancer AJCC v7; Stage IVB Uterine Corpus Cancer AJCC v7
Gynecologic Oncology Group
2014-03-17 PHASE2; PHASE3
NCT02186847 COMPLETED
Adenosquamous Lung Carcinoma; Bronchioloalveolar Carcinoma; Large Cell Lung Carcinoma; Lung Adenocarcinoma; Non-Small Cell Lung Carcinoma; Recurrent Non-Small Cell Lung Carcinoma; Squamous Cell Lung Carcinoma; Stage IIIA Non-Small Cell Lung Cancer; Stage IIIB Non-Small Cell Lung Cancer
NRG Oncology
2014-08 PHASE2
NCT03492047 COMPLETED
Peripheral Neuropathy Due to Chemotherapy
Ain Shams University
2018-04-01 PHASE1; PHASE2
NCT03058939 WITHDRAWN
Breast Cancer; Breast Cancer Stage II; Breast Cancer Stage III
University of Chicago
2018-11 PHASE2
NCT03307148 COMPLETED
Pancreatic Adenocarcinoma
Barts & The London NHS Trust
2016-01-15 PHASE1
NCT03432598 COMPLETED
Locally Advanced Lung Cancer; Metastatic Lung Cancer
BeiGene
2017-08-24 PHASE2
NCT02631876 COMPLETED
Epithelial Ovarian Cancer; Primary Peritoneal Carcinoma; Fallopian Tube Cancer; Ovarian Cancer
ImmunoGen, Inc.
2016-03-02 PHASE3
NCT03169777 WITHDRAWN
Colorectal Cancer
ImmunityBio, Inc.
2018-08 PHASE1; PHASE2
NCT02272790 COMPLETED
Ovarian, Fallopian Tube, Peritoneal Cancer, P53 Mutation
AstraZeneca
2015-01-30 PHASE2
NCT03072992 COMPLETED
Advanced Breast Cancer; Metastatic Breast Cancer
National Center of Oncology, Armenia
2017-03-20 PHASE2
NCT01367301 TERMINATED
Stage IA Uterine Sarcoma; Stage IB Uterine Sarcoma; Stage IC Uterine Sarcoma; Stage IIA Uterine Sarcoma; Stage IIB Uterine Sarcoma; Stage IIIA Uterine Sarcoma; Stage IIIB Uterine Sarcoma; Stage IIIC Uterine Sarcoma; Stage IVA Uterine Sarcoma; Stage IVB Uterine Sarcoma; Uterine Carcinosarcoma
Albert Einstein College of Medicine
2011-07-08
NCT03574649 WITHDRAWN
Non Small Cell Lung Cancer
ImmunityBio, Inc.
2018-06 PHASE2
NCT02194166 COMPLETED
Breast Cancer
Hoffmann-La Roche
2014-07-18 PHASE3
NCT01185171 COMPLETED
Head and Neck Cancer
University of Chicago
2003-01-27 PHASE2
NCT02855788 UNKNOWN
Metastatic Gastric Cancer; Locally Advanced Gastric Cancer
Huashan Hospital
2015-05 PHASE2
NCT02134067 TERMINATED
Advanced Solid Tumors
Taiho Oncology, Inc.
2014-08 PHASE1
NCT02500810 UNKNOWN
Neurotoxicity
Peking University Cancer Hospital & Institute
2015-07 PHASE2
NCT01628380 UNKNOWN
Ovarian Neoplasms
A.O. Ospedale Papa Giovanni XXIII
2012-06 PHASE3
NCT02622074 COMPLETED
Triple Negative Breast Neoplasms
Merck Sharp & Dohme LLC
2016-01-27 PHASE1
NCT02487277 TERMINATED
Adenocarcinoma
Andrew Ko
2015-07-14 PHASE2
NCT01435018 COMPLETED
HIV-1 Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
2013-10-01 PHASE3
NCT02685059 COMPLETED
Breast Cancer
GBG Forschungs GmbH
2016-06 PHASE2
NCT02559674 COMPLETED
Advanced Pancreatic Cancer
Altor BioScience
2016-07 PHASE1
NCT02967133 TERMINATED
Non-Small-Cell Lung Cancer Metastatic; Non-Small Cell Carcinoma of Lung, TNM Stage 4; Nonsmall Cell Lung Cancer; Non Small Cell Lung Cancer Recurrent
Alliance Foundation Trials, LLC.
2016-12 PHASE2
NCT02470468 COMPLETED
Stage IV Non-small Cell Lung Cancer
SOTIO a.s.
2014-12 PHASE1; PHASE2
NCT00997906 UNKNOWN
Head and Neck Cancer
National Cancer Centre, Singapore
2009-09-15 PHASE2; PHASE3
NCT01971281 UNKNOWN
Pancreatic Adenocarcinoma
NovoCure Ltd.
2013-11 PHASE1; PHASE2
NCT02012192 TERMINATED
Epithelial Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer
Medical University Innsbruck
2014-07-04 PHASE1; PHASE2
NCT02539225 COMPLETED
Metastatic Gastric Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma
Eli Lilly and Company
2015-10-05 PHASE2
NCT02344095 COMPLETED
Epithelial Ovarian Carcinoma; Fallopian Tube Carcinoma; Primary Peritoneal Carcinoma
Seoul National University Hospital
2014-12 PHASE1
NCT02051868 UNKNOWN
Squamous Cell Carcinoma of the Anus
Royal Marsden NHS Foundation Trust
2013-12 PHASE2
NCT03388892 COMPLETED
Kidney Failure, Chronic; Angioplasty; Dialysis
National Taiwan University Hospital Hsin-Chu Branch
2015-01-29
NCT01862081 COMPLETED
Breast Cancer, Non-small Lung Cancer
Genentech, Inc.
2013-07-16 PHASE1
NCT02506803 UNKNOWN
Pancreatic Cancer
Wakayama Medical University
2015-07 PHASE1
NCT01654146 UNKNOWN
Ovarian Cancer
Medical Research Council
2011-06 PHASE3
NCT01463072 ACTIVE_NOT_RECRUITING
Locally Advanced Breast Carcinoma; Metastatic Breast Carcinoma; Recurrent Breast Carcinoma; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7; Stage IV Breast Cancer AJCC v6 and v7
City of Hope Medical Center
2012-06-19 PHASE2
NCT01215136 TERMINATED
Transitional Cell Carcinoma; Bladder Carcinoma; Urothelial Carcinoma
Matthew Galsky
2010-12 PHASE2
NCT02514421 COMPLETED
Pancreatic Adenocarcinoma
The University of Texas Health Science Center, Houston
2015-07 PHASE1
NCT01701349 WITHDRAWN
Anaplastic Thyroid Cancer
Mateon Therapeutics
2015-03 PHASE3
NCT02551055 TERMINATED
Advanced and Metastatic Gastric or Gastroesophageal Adenocarcinoma
Millennium Pharmaceuticals, Inc.
2015-10-15 PHASE1
NCT01967199 TERMINATED
Coronary Restenosis
Seung-Jung Park
2013-04-18 PHASE4
NCT00660218 COMPLETED
Carcinoma, Squamous Cell
State University of New York - Upstate Medical University
2008-03 PHASE1; PHASE2
NCT02124317 UNKNOWN
Advanced Pancreatic Cancer
Chinese PLA General Hospital
2014-04 PHASE2
NCT01953536 WITHDRAWN
Breast Neoplasms
Endocyte
2014-04 PHASE2
NCT02429622 COMPLETED
Esophageal Neoplasms
Chinese Academy of Medical Sciences
2015-01 PHASE1; PHASE2
NCT02772224 UNKNOWN
Peripheral Arterial Disease
Shanghai 10th People's Hospital
2016-06 PHASE1
NCT01836432 TERMINATED
Pancreatic Cancer; Pancreatic Carcinoma Non-resectable; Locally Advanced Malignant Neoplasm
NewLink Genetics Corporation
2013-05 PHASE3
NCT00575952 COMPLETED
Endometrial Adenosquamous Carcinoma; Endometrial Clear Cell Adenocarcinoma; Endometrial Mixed Adenocarcinoma; Endometrial Serous Adenocarcinoma; Endometrial Squamous Cell Carcinoma; Endometrial Undifferentiated Carcinoma; Recurrent Uterine Corpus Carcinoma; Stage IIIA Uterine Corpus Cancer; Stage IIIC Uterine Corpus Cancer; Stage IVA Uterine Corpus Cancer; Stage IVB Uterine Corpus Cancer
Gynecologic Oncology Group
2008-01-17 PHASE1
NCT02319889 TERMINATED
Stage I Non-Small Cell Lung Cancer; Stage II Non-Small Cell Lung Cancer
Case Comprehensive Cancer Center
2016-02-02 EARLY_PHASE1
NCT01962948 TERMINATED
Recurrent Fallopian Tube Cancer; Recurrent Ovarian Epithelial Cancer; Recurrent Primary Peritoneal Cavity Cancer
Fox Chase Cancer Center
2013-10-09 PHASE1; PHASE2
NCT01216111 COMPLETED
Triple Negative Breast Cancer
Fudan University
2011-01-01 PHASE3
NCT02570711 TERMINATED
Metastatic Pancreatic Cancer
Acerta Pharma BV
2015-10-13 PHASE2
NCT01493843 COMPLETED
Non-Small Cell Lung Cancer
Genentech, Inc.
2012-01-20 PHASE2
NCT01186991 COMPLETED
Breast Cancer
Genentech, Inc.
2011-03 PHASE2
NCT01256268 COMPLETED
Endometrial Cancer; Ovarian Cancer
H. Lee Moffitt Cancer Center and Research Institute
2011-06-13 PHASE1
NCT01858883 COMPLETED
Solid Tumors; Pancreatic Cancer
Incyte Corporation
2013-06 PHASE1; PHASE2
NCT01280058 COMPLETED
Pancreatic Acinar Cell Carcinoma; Pancreatic Ductal Adenocarcinoma; Recurrent Pancreatic Carcinoma; Stage IV Pancreatic Cancer
National Cancer Institute (NCI)
2010-12 PHASE2
NCT02016274 UNKNOWN
Esophageal Squamous Cell Cancer
Shen Lin
2013-12 PHASE2
NCT00933426 TERMINATED
Prostate Cancer
M.D. Anderson Cancer Center
2009-08 PHASE1
NCT01970579 COMPLETED
Stenosis; Restenosis
B. Braun Melsungen AG
2013-10 PHASE3
NCT01496742 COMPLETED
Non-Squamous Non-Small Cell Lung Cancer
Genentech, Inc.
2012-04 PHASE2
NCT00617409 COMPLETED
Small Cell Lung Cancer
H. Lee Moffitt Cancer Center and Research Institute
2007-10-02 PHASE2
NCT01694576 TERMINATED
Nasopharyngeal Carcinoma
Jiangsu Cancer Institute & Hospital
2012-09 PHASE2
NCT01936974 TERMINATED
Ovarian Carcinoma; Fallopian Tube Carcinoma; Peritoneal Carcinoma
Western Regional Medical Center
2013-09 PHASE2
NCT01746771 COMPLETED
HER-2 Positive Advanced Gastric Cancer
Hanmi Pharmaceutical Company Limited
2012-11 PHASE1; PHASE2
NCT02474186 COMPLETED
Breast Cancer; Metastatic Breast Cancer; Solid Tumor
NYU Langone Health
2003-04 PHASE2
NCT01317615 COMPLETED
Carcinoma, Large Cell; Neuroendocrine Tumors
Novartis Pharmaceuticals
2011-04 PHASE4
NCT01764022 COMPLETED
Human Epithelial Receptor (HER)-2 Positive Breast Cancer
Biocad
2012-10 PHASE3
NCT00108745 UNKNOWN
Fallopian Tube Clear Cell Adenocarcinoma; Fallopian Tube Endometrioid Adenocarcinoma; Fallopian Tube Mucinous Adenocarcinoma; Fallopian Tube Serous Adenocarcinoma; Fallopian Tube Transitional Cell Carcinoma; Fallopian Tube Undifferentiated Carcinoma; Ovarian Brenner Tumor; Ovarian Clear Cell Adenocarcinoma; Ovarian Endometrioid Adenocarcinoma; Ovarian Mucinous Adenocarcinoma; Ovarian Seromucinous Carcinoma; Ovarian Serous Adenocarcinoma; Ovarian Transitional Cell Carcinoma; Ovarian Undifferentiated Carcinoma; Primary Peritoneal Serous Adenocarcinoma; Stage IIIA Fallopian Tube Cancer AJCC v7; Stage IIIA Ovarian Cancer AJCC v6 and v7; Stage IIIA Primary Peritoneal Cancer AJCC v7; Stage IIIB Fallopian Tube Cancer AJCC v7; Stage IIIB Ovarian Cancer AJCC v6 and v7; Stage IIIB Primary Peritoneal Cancer AJCC v7; Stage IIIC Fallopian Tube Cancer AJCC v7; Stage IIIC Ovarian Cancer AJCC v6 and v7; Stage IIIC Primary Peritoneal Cancer AJCC v7; Stage IV Fallopian Tube Cancer AJCC v6 and v7; Stage IV Ovarian Cancer AJCC v6 and v7; Stage IV Primary Peritoneal Cancer AJCC v7
GOG Foundation
2005-03-21 PHASE3
NCT02065466 WITHDRAWN
Metastatic Melanoma; Brain Metastases
University of Arizona
2014-07 PHASE1; PHASE2
NCT01487226 UNKNOWN
Cervical Cancer
Korean Gynecologic Oncology Group
2008-01 PHASE2
NCT01851174 TERMINATED
Pancreatic Carcinoma Non-resectable; Stage IV Pancreatic Cancer
Western Regional Medical Center
2013-02 PHASE2
NCT01309607 UNKNOWN
ErbB2-Positive Stage I-III Breast Cancer
National University Hospital, Singapore
2011-04 PHASE2
NCT01454778 COMPLETED
Peripheral Vascular Disease
Patrick Kelly
2011-04
NCT01688791 TERMINATED
Advanced Cancer
Endocyte
2012-12 PHASE1
NCT01086696 TERMINATED
Breast Cancer; Lung Cancer; Renal Cancer; Adrenal Cancer
National Cancer Institute (NCI)
2010-03-09 EARLY_PHASE1
NCT00602797 COMPLETED
Recurrent Non-Small Cell Lung Carcinoma; Stage IV Non-Small Cell Lung Cancer
University of Nebraska
2007-12-17 PHASE2
NCT00976911 COMPLETED
Ovarian Cancer
Hoffmann-La Roche
2009-10-29 PHASE3
NCT01570582 UNKNOWN
Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cancer
Korean Gynecologic Oncology Group
2010-03 PHASE2
NCT01594684 UNKNOWN
Catherization
Prof. Dr. med. Gunnar Tepe
2012-01 PHASE2; PHASE3
NCT01236716 COMPLETED
Carcinoma, Non-Small-Cell Lung
Chinese Society of Lung Cancer
2010-11 PHASE2
NCT01085136 COMPLETED
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim
2010-02 PHASE3
NCT01293630 COMPLETED
Advanced Solid Tumors
Sanofi
2011-01 PHASE1
NCT01268059 TERMINATED
Non-small Cell Lung Cancer
MedImmune LLC
2010-12-16 PHASE1; PHASE2
NCT01200342 TERMINATED
Melanoma
M.D. Anderson Cancer Center
2010-12 PHASE2
NCT00998192 COMPLETED
Metastatic or Recurrent Squamous Cell Carcinoma of the Lung
Oncolytics Biotech
2009-10 PHASE2
NCT00915018 COMPLETED
Breast Cancer
Puma Biotechnology, Inc.
2009-08-21 PHASE2
NCT00887575 COMPLETED
Breast Cancer
SCRI Development Innovations, LLC
2009-06 PHASE1; PHASE2
NCT01617928 COMPLETED
Solid Tumors
AbbVie (prior sponsor, Abbott)
2012-05 PHASE1
NCT01263613 COMPLETED
Breast Cancer
University of Wisconsin, Madison
2010-12 EARLY_PHASE1
NCT01579578 TERMINATED
Metastatic, Gastric or Gastro-oesophageal Junction, Cancer
AstraZeneca
2012-04 PHASE2
NCT01321775 UNKNOWN
Breast Cancer
Hospital Universitario Madrid Sanchinarro
2009-08 PHASE2
NCT00876486 COMPLETED
Breast Cancer
Samyang Biopharmaceuticals Corporation
2008-12 PHASE3
NCT00948675 COMPLETED
Advanced Non-Small Cell Lung Cancer
Eli Lilly and Company
2009-09-01 PHASE3
NCT01364012 COMPLETED
Non-Small Cell Lung Cancer
Hoffmann-La Roche
2011-05-23 PHASE3
NCT01527864 UNKNOWN
Non Small Cell Lung Cancer
Beijing Protgen Biotechnology Development Co., Ltd.
2011-05 PHASE2
NCT01229930 COMPLETED
Cervical Cancer
University of Glasgow
2010-06 PHASE2
NCT01042925 COMPLETED
Breast Cancer; Breast Neoplasms
Sanofi
2010-02 PHASE1; PHASE2
NCT00960297 TERMINATED
Non-Small Cell Lung Cancer
SCRI Development Innovations, LLC
2009-08 PHASE2
NCT01196741 COMPLETED
Ovarian Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer
University College, London
2011-03 PHASE2; PHASE3
NCT01593306 UNKNOWN
Carcinoma Cervix
Indira Gandhi Medical College, Shimla
2011-07 PHASE3
NCT01161186 COMPLETED
Pancreatic Neoplasms; Pancreatic Cancer; Adenocarcinoma
University of California, San Francisco
2010-07 PHASE1
NCT01083537 TERMINATED
Ovarian Cancer; Peritoneal Cancer; Fallopian Tube Cancer; Bowel Obstruction
University Health Network, Toronto
2010-02 PHASE1; PHASE2
NCT02133612 COMPLETED
Esophageal Cancer
Chinese Academy of Medical Sciences
2007-12 PHASE2
NCT00823186 UNKNOWN
Cervical Cancer
Chang Gung Memorial Hospital
2009-02 PHASE1
NCT00281515 COMPLETED
Epithelial Ovarian Cancer
AGO Study Group
2006-01 PHASE2
NCT01336049 UNKNOWN
Esophageal Squamous Cell Cancer
Peking University
2011-03 PHASE2
NCT00954642 COMPLETED
Solid Cancers
Genentech, Inc.
2009-08 PHASE1
NCT00846027 COMPLETED
Breast Cancer
Hoffmann-La Roche
2009-01 PHASE2
NCT01264328 COMPLETED
Head and Neck Cancer
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello
2011-03-09 PHASE2
NCT00550537 COMPLETED
Lung Cancer
Vanderbilt-Ingram Cancer Center
2007-10 PHASE2
NCT00301028 COMPLETED
Head and Neck Cancer
M.D. Anderson Cancer Center
2006-04 PHASE2
NCT01329640 TERMINATED
Locally Advanced HER2-positive Breast Cancer
Instituto do Cancer do Estado de São Paulo
2010-09 PHASE2
NCT00870038 UNKNOWN
Angioplasty, Transluminal, Percutaneous Coronary; Percutaneous Coronary Intervention
Ospedale della Misericordia
2010-12 PHASE4
NCT00626561 TERMINATED
Cervical Cancer; Uterine Cancer
M.D. Anderson Cancer Center
2008-02 PHASE2
NCT00231868 COMPLETED
Uterine Cancer
Montefiore Medical Center
2001-12 PHASE2
NCT00334321 COMPLETED
Endometrial Cancer
Washington University School of Medicine
2006-04 PHASE1
NCT00256243 COMPLETED
Breast Cancer
Rita Sanghvi, Mehta
2004-04 PHASE2
NCT00572078 COMPLETED
SOLID TUMORS
Safi Shahda
2008-01-23 PHASE1
NCT00634595 UNKNOWN
Head and Neck Squamous Carcinoma; Nasopharyngeal Carcinoma
Sun Yat-sen University
2008-03 PHASE2
NCT01240642 TERMINATED
Metastatic Cancer With Impaired Renal Function; Metastatic Cancer With Normal Renal Function
Novartis Pharmaceuticals
2010-01 PHASE1
NCT00584909 TERMINATED
Uterine Cancer
University of Alabama at Birmingham
2006-03 PHASE2
NCT00517621 COMPLETED
Ovarian Cancer; Fallopian Tube Cancer; Peritoneal Neoplasms
ARCAGY/ GINECO GROUP
2006-02 PHASE2
NCT00550771 COMPLETED
Breast Neoplasm
Merck Sharp & Dohme LLC
2007-07-16 PHASE2
NCT00404144 COMPLETED
Coronary Stenosis
Heart Centre Rotenburg
2006-01 PHASE2
NCT00662129 COMPLETED
Breast Cancer
Alliance for Clinical Trials in Oncology
2008-11 PHASE2
NCT00716417 COMPLETED
Neoplasms
Boehringer Ingelheim
2008-07-01 PHASE1
NCT00687817 COMPLETED
Non-small Cell Lung Cancer
Peregrine Pharmaceuticals
2008-06 PHASE2
NCT00919880 COMPLETED
Breast Cancer
Tao OUYANG
2009-07 PHASE2
NCT00934752 COMPLETED
Coronary Artery Stenosis
C. R. Bard
2009-07 PHASE1; PHASE2
NCT00496028 COMPLETED
Neoplasms
AstraZeneca
2007-03 PHASE1
NCT00455533 COMPLETED
Breast Cancer
Bristol-Myers Squibb
2007-10 PHASE2
NCT00533936 UNKNOWN
Breast Cancer
Instituto Nacional de Cancerologia, Columbia
2006-09 PHASE2
NCT00457119 COMPLETED
Non Small Cell Lung Cancer
Novartis Pharmaceuticals
2007-02 PHASE1
NCT00495664 COMPLETED
Acute Myocardial Infarction
The Hospital District of Satakunta
2005-12
NCT00786110 UNKNOWN
Adrenocortical Carcinoma
University of Turin, Italy
2008-04 PHASE2
NCT00708812 COMPLETED
Advanced Non-small Cell Lung Cancer
Shandong Simcere-Medgenn Bio-pharmaceutical Co., Ltd
2007-07 PHASE2
NCT00704145 COMPLETED
Coronary Artery Disease
A.O. Ospedale Papa Giovanni XXIII
2007-11 PHASE4
NCT00610714 COMPLETED
Ovarian Neoplasms; Ovarian Cancer
AstraZeneca
2008-04 PHASE2
NCT00407888 COMPLETED
Estrogen Receptor-positive Breast Cancer; HER2-positive Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer
University of Washington
2006-05 PHASE2
NCT00434252 COMPLETED
Melanoma
Genentech, Inc.
2007-02 PHASE2
NCT00508625 COMPLETED
Non-Small Cell Lung Cancer
Amgen
2006-06 PHASE2
NCT00113516 COMPLETED
Non-small Cell Lung Cancer
Pfizer
2005-09 PHASE2
NCT00189553 COMPLETED
Ovarian Cancer; Fallopian Tube Cancer
ARCAGY/ GINECO GROUP
2005-04 PHASE3
NCT00971867 COMPLETED
Head and Neck Cancer
Bristol-Myers Squibb
2006-08-04 PHASE2
NCT00666692 COMPLETED
Non-small Cell Lung Cancer
Abbott
2008-04 PHASE1
NCT02004093 COMPLETED
Ovarian Cancer
Hoffmann-La Roche
2005-12 PHASE2
NCT00130546 COMPLETED
Coronary Artery Disease
University Hospital Freiburg
2004-11 PHASE3
NCT00606125 COMPLETED
Neoplasms
Bayer
2007-05 PHASE1
NCT00497367 COMPLETED
Cardiovascular Diseases
Boston Scientific Corporation
2007-07 PHASE1
NCT00133237 COMPLETED
Coronary Disease
Deutsches Herzzentrum Muenchen
2005-07 PHASE4
NCT00752362 COMPLETED
Coronary Restenosis
Sahajanand Medical Technologies Limited
2006-03 PHASE4
NCT00369070 TERMINATED
Advanced Non-squamous NSCLC
Amgen
2007-01-31 PHASE2
NCT00561795 COMPLETED
Primary Peritoneal Carcinoma; Tumor; Epithelial Ovarian Cancer; Uterine Disease; Cervix Diseases; Neoplasms, Ovarian; Cancer
GlaxoSmithKline
2007-09 PHASE2
NCT00158379 COMPLETED
Ovarian Cancer
North Eastern German Society of Gynaecological Oncology
2003-07 PHASE2
NCT00094861 COMPLETED
Dysphagia; Non-Small Cell Lung Cancer; Lung Cancer
Swedish Orphan Biovitrum
2005-01 PHASE2
NCT00068757 COMPLETED
Breast Cancer
European Organisation for Research and Treatment of Cancer - EORTC
2003-08 PHASE1
NCT00307255 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
UNC Lineberger Comprehensive Cancer Center
2006-08 PHASE1
NCT00085501 COMPLETED
Lung Cancer
SWOG Cancer Research Network
2004-07 PHASE2
NCT00387374 COMPLETED
Adenosquamous Cell Lung Cancer; Drug/Agent Toxicity by Tissue/Organ; Hemoptysis; Squamous Cell Lung Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IV Non-small Cell Lung Cancer
National Cancer Institute (NCI)
2006-10 PHASE2
NCT00004125 COMPLETED
Breast Cancer
Eastern Cooperative Oncology Group
1999-11-16 PHASE3
NCT00095914 COMPLETED
Unspecified Adult Solid Tumor, Protocol Specific
National Institutes of Health Clinical Center (CC)
2004-09 PHASE1
NCT00146562 COMPLETED
Breast Cancer; Stage I Breast Cancer; Stage II Breast Cancer
Harold J. Burstein, MD, PhD
2003-07 PHASE2
NCT00085839 COMPLETED
Non-Small Cell Lung Cancer
OSI Pharmaceuticals
2004-02 PHASE2
NCT00014118 COMPLETED
Head and Neck Cancer
Eastern Cooperative Oncology Group
2001-06-06 PHASE2
NCT00094835 COMPLETED
Lung Cancer; Non-Small Cell Lung Cancer
Amgen
2005-01 PHASE1; PHASE2
NCT00113438 COMPLETED
Cancer; Tumor
Mateon Therapeutics
2005-03 PHASE2
NCT00301080 TERMINATED
Neurotoxicity; Pain; Breast Cancer
Northwestern University
2006-02 PHASE3
NCT00005046 COMPLETED
Ovarian Cancer; Primary Peritoneal Cavity Cancer
Gynecologic Oncology Group
2000-04 PHASE1
NCT00255762 COMPLETED
Recurrent Melanoma; Stage IV Melanoma
National Cancer Institute (NCI)
2005-12 PHASE2
NCT00111787 COMPLETED
Neoplasms, Breast
GlaxoSmithKline
2005-04-11 PHASE2
NCT00106587 COMPLETED
Coronary Restenosis
University Hospital, Saarland
2003-12 PHASE1; PHASE2
NCT00039780 COMPLETED
Breast Neoplasms; Breast Diseases; Metastases, Neoplasm
BioNumerik Pharmaceuticals, Inc.
2001-09 PHASE3
NCT00161278 TERMINATED
Advanced Non-Small Cell Lung Cancer
University of Michigan Rogel Cancer Center
2004-12 PHASE2
NCT00026104 COMPLETED
Adenocarcinoma of the Pancreas; Stage II Pancreatic Cancer; Stage III Pancreatic Cancer
National Cancer Institute (NCI)
2001-11 PHASE2
NCT00062062 COMPLETED
Lung Cancer
Alliance for Clinical Trials in Oncology
2004-10 PHASE2
NCT00055835 COMPLETED
Bladder Cancer; Urethral Cancer
SWOG Cancer Research Network
2002-11 PHASE2
NCT00002984 COMPLETED
Esophageal Cancer
UNC Lineberger Comprehensive Cancer Center
1997-03 PHASE1; PHASE2
NCT00532285 TERMINATED
Breast Cancer
National Cancer Center, Korea
2005-09 PHASE2
NCT00021333 COMPLETED
Head and Neck Cancer; Lung Cancer
Fox Chase Cancer Center
1999-09 PHASE2
NCT00280787 COMPLETED
Non Small Cell Lung Cancer
UNC Lineberger Comprehensive Cancer Center
2003-11 PHASE2
NCT00136175 COMPLETED
Bladder Cancer
University of Michigan Rogel Cancer Center
1999-11 PHASE2
NCT01023204 COMPLETED
Breast Cancer
Bristol-Myers Squibb
2002-10 PHASE2
NCT00006248 COMPLETED
Head and Neck Cancer
SWOG Cancer Research Network
2000-11 PHASE2
NCT00003614 COMPLETED
Prostate Cancer
Eastern Cooperative Oncology Group
1999-02-04 PHASE2
NCT00004055 COMPLETED
Lung Cancer
Alliance for Clinical Trials in Oncology
1999-11 PHASE2
NCT00003691 COMPLETED
Endometrial Cancer
Gynecologic Oncology Group
1998-12 PHASE3
NCT00038246 COMPLETED
Prostate Cancer
M.D. Anderson Cancer Center
2000-10 PHASE1; PHASE2
NCT00003624 TERMINATED
Cervical Cancer; Endometrial Cancer; Fallopian Tube Cancer; Neurotoxicity; Ovarian Cancer; Primary Peritoneal Cavity Cancer; Sarcoma
Gynecologic Oncology Group
1998-12 PHASE2
NCT00299026 COMPLETED
Coronary Artery Disease
Boston Scientific Corporation
2001-06 PHASE2
NCT00170664 COMPLETED
Ovarian Cancer
North Eastern German Society of Gynaecological Oncology
1999-01 PHASE2
NCT00003587 COMPLETED
Lung Cancer
SWOG Cancer Research Network
1998-10 PHASE2
NCT00003589 COMPLETED
Lung Cancer
European Organisation for Research and Treatment of Cancer - EORTC
1998-08 PHASE3
NCT00003230 COMPLETED
Leukemia
Swiss Cancer Institute
1998-01 PHASE1; PHASE2
NCT00003378 TERMINATED
Ovarian Cancer; Primary Peritoneal Cavity Cancer
Gynecologic Oncology Group
1998-08 PHASE1
NCT00074854 COMPLETED
Lung Neoplasms
Pfizer
2002-05 PHASE1; PHASE2
NCT00088088 COMPLETED
Stage IIIB Non-Small Cell Lung Cancer; Stage IV Non-Small Cell Lung Cancer
Synta Pharmaceuticals Corp.
2004-03 PHASE1; PHASE2
NCT00340184 COMPLETED
Cervical Cancer
Korean Gynecologic Oncology Group
2004-08 PHASE2
NCT00003327 UNKNOWN
Head and Neck Cancer
Theradex
1997-09 PHASE2
NCT00006049 UNKNOWN
Lung Cancer
AstraZeneca
2000-05 PHASE3
NCT00003643 UNKNOWN
Extragonadal Germ Cell Tumor; Teratoma; Testicular Germ Cell Tumor
European Organisation for Research and Treatment of Cancer - EORTC
1998-10 PHASE2; PHASE3
NCT00002917 COMPLETED
Bladder Cancer
Mary Babb Randolph Cancer Center at West Virginia University Hospitals
1996-11 PHASE1; PHASE2
NCT01224652 UNKNOWN
Gastric Cancer
Korean Cancer Study Group
PHASE3
NCT00046514 COMPLETED
Breast Neoplasms; Metastases, Neoplasm
Celgene Corporation
2001-06 PHASE2
NCT00301730 COMPLETED
Breast Cancer; Metastatic Cancer
National Cancer Institute (NCI)
2005-10 PHASE1
NCT00189566 COMPLETED
Ovarian Cancer; Fallopian Tube Cancer; Malignant Tumor of Peritoneum
ARCAGY/ GINECO GROUP
2004-04 PHASE2
NCT00019812 COMPLETED
Breast Cancer
National Institutes of Health Clinical Center (CC)
1999-08 PHASE2
NCT00154778 COMPLETED
Gastric Cancer
National Taiwan University Hospital
2003-03 PHASE2
NCT00477867 WITHDRAWN
Ovarian Cancer
Gynecologic Oncology Group

(data from https://clinicaltrials.gov, updated on 2026-04-14)

Check the Paclitaxel product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Paclitaxel binds to and stabilizes microtubule polymers, disrupting normal dynamic instability during spindle assembly and arresting cells in the G2-M phase of the cell cycle. This inhibition of mitotic progression triggers apoptotic cell death and autophagy, providing the pharmacological basis for halting tumor cell proliferation in clinical indications such as breast cancer and esophageal squamous cell carcinoma.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

Note: Technical data last updated: Sep 1, 2026.