Minoxidil

For research use only.

Catalog No.S1383 Synonyms: U-10858

1 publication

Minoxidil Chemical Structure

CAS No. 38304-91-5

Minoxidil (U-10858) is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Minoxidil is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth.

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Selleck's Minoxidil has been cited by 1 publication

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  • Effect of Rhiz in combination with potassium channel openers Minox (A) on viability of PC-3 and DU145 cells. Cells were co-treated with indicated concentrations of the drugs for 48 h. Cell viability was measured by MTT assay.

    Oncotarget, 2016, 7(43):69703-69717. Minoxidil purchased from Selleck.

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Description Minoxidil (U-10858) is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Minoxidil is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth.

Protocol

References

Solubility (25°C)

In vitro DMSO 0.25 mg/mL (1.19 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 209.25
Formula

C9H15N5O

CAS No. 38304-91-5
Storage powder
in solvent
Synonyms U-10858
Smiles C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O

In vivo Formulation Calculator (Clear solution)

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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

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Molecular Weight Calculator

Molecular Weight Calculator

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Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT02198261 Completed Drug: 5% minoxidil topical foam Androgenetic Alopecia Applied Biology Inc. July 2014 --
NCT02206802 Completed Drug: 5% minoxidil topical foam Alopecia|Female Pattern Hair Loss Applied Biology Inc. July 2014 --
NCT01650272 Unknown status Drug: 5% MInoxidil milky lotion|Drug: 5% Minoxidil solution Objective (Goal)|Self-Assessment|Adverse Effects Siriraj Hospital June 2012 Phase 1|Phase 2
NCT01309191 Completed Drug: Minoxidil|Other: Placebo Androgenetic Alopecia University Hospitals Cleveland Medical Center|University of California San Francisco|Kaiser Permanente April 2011 Not Applicable

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Potassium Channel Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID