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6-Benzylaminopurine ROS chemical

Name: 6-Benzylaminopurine
Brand: Selleck Chemicals
SKU: S4511
Availability: InStock
Rating: 5 (1 reviews)

Cat.No.S4511

6-Benzylaminopurine is a first-generation synthetic cytokinin which could regulate the activities of the antioxidant defense system of plants.Its treatment elicits plant growth and development.

Chemical Structure

Molecular Weight: 225.25

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Quality Control

Batch: S451101 DMSO]45 mg/mL]false]Water]Insoluble]false]Ethanol]Insoluble]false Purity: 99.97%

Cited in Nature Medicine for its top-tier quality
COA
NMR
SDS
Datasheet

99.97

Related Targets	PD-1/PD-L1 CXCR STING AhR Immunology & Inflammation related CD markers Interleukins Anti-infection Antioxidant COX
Other ROS Inhibitors	Piperlongumine MitoQ (Mitoquinone) Mesylate H2DCFDA (DCFH-DA) Neohesperidin Carnosic acid Gallic acid (20R)Ginsenoside Rg3 Pyrogallol Idebenone Asiaticoside

Solubility

In vitro
Batch:

DMSO : 45 mg/mL (199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

% Tween 80

% ddH₂O

% DMSO

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	225.25	Formula	C₁₂H₁₁N₅	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	1214-39-7	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	N/A			Smiles	C1=CC=C(C=C1)CNC2=NC=NC3=C2NC=N3

Mechanism of Action

In vitro	6-BA promotes plant branching, increases resistance to disease, drought, cold, or high salt levels and increases flowering and fruit set by decreasing flower drop.
References	[1] http://www.planthormones.net/benzylaminopurine-6-ba/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT04333290	Not yet recruiting	Healthy	Robert Fox\|Case Western Reserve University\|The Cleveland Clinic	March 2025	Early Phase 1
NCT03335228	Not yet recruiting	Frontal Fibrosing Alopecia	University of Minnesota	March 1 2025	Not Applicable
NCT05744817	Not yet recruiting	Hypertension	University of Arizona\|American Heart Association	November 15 2024	Not Applicable

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