FTO

FTO Products

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  • FTO Inhibitors (6)
  • New FTO Products
Catalog No. Product Name Information Product Use Citations Product Validations
S8837 FB23-2 FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM.
J Exp Clin Cancer Res, 2023, 42(1):217
Cell Death Discov, 2023, 9(1):457
Int J Mol Sci, 2023, 24(2)1624
S4295 Meclofenamate Sodium Meclofenamate Sodium(CI 583) is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. Meclofenamate Sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor.
Adv Sci (Weinh), 2023, e2307206.
Int J Mol Sci, 2023, 24(2)1624
Gynecol Endocrinol, 2023, 10.1080/09513590.2023.2276167
S2400 Rheic Acid Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes.
Cell Chem Biol, 2016, 23(3):415-25
S9876 Dac51 Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation.
Int J Mol Sci, 2023, 24(9)7957
S6291 FB23 FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
Oncogene, 2022, 41(20):2860-2872
S9946 Bisantrene (CS1)

Bisantrene (CS1, NSC-337766, CL 216,942) is an anthracene derivative with anti-tumor activity. Bisantrene also is a potent and selective FTO inhibitor.

S8837 FB23-2 FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits FTO's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM.
J Exp Clin Cancer Res, 2023, 42(1):217
Cell Death Discov, 2023, 9(1):457
Int J Mol Sci, 2023, 24(2)1624
S4295 Meclofenamate Sodium Meclofenamate Sodium(CI 583) is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. Meclofenamate Sodium is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor.
Adv Sci (Weinh), 2023, e2307206.
Int J Mol Sci, 2023, 24(2)1624
Gynecol Endocrinol, 2023, 10.1080/09513590.2023.2276167
S2400 Rheic Acid Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes.
Cell Chem Biol, 2016, 23(3):415-25
S9876 Dac51 Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation.
Int J Mol Sci, 2023, 24(9)7957
S6291 FB23 FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. FB23 directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.
Oncogene, 2022, 41(20):2860-2872
S9946 Bisantrene (CS1)

Bisantrene (CS1, NSC-337766, CL 216,942) is an anthracene derivative with anti-tumor activity. Bisantrene also is a potent and selective FTO inhibitor.

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Tags: FTO inhibitor|FTO agonist|FTO activator|FTO inducer|FTO antagonist|FTO signaling pathway|FTO assay kit