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Australia
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Austria
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Belgium
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Brazil
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Canada
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China
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Czech Republic
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Denmark
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Finland
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France
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Germany
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Greece
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Hong Kong
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Hungary
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Iceland
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India
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Ireland
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Israel
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Italy
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Japan
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Korea
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Luxembourg
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Malaysia
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Netherlands
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New Zealand
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Norway
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Poland
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Qatar
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Romania
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Saudi Arabia
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Singapore
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Spain
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Sweden
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Switzerland
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Taiwan
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Turkey
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United Kingdom
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United States
FTO
| Cat.No. | Product Name | Information | Product Use Citations | Product Validations |
|---|---|---|---|---|
| S8837 | FB23-2 | FB23-2 is a potent and selective FTO inhibitor that directly binds to FTO and selectively inhibits this compound's N6-methyladenosine (m6A) demethylase activity with IC50 of 2.6 μM. |
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| S9876 | Dac51 | Dac51 is a potent FTO inhibitor with an IC50 of 0.4 μM for inhibiting FTO demethylation. |
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| S6291 | FB23 | FB23 is a potent and selective inhibitor of FTO demethylase with IC50 of 60 nM. This compound directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity. |
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| S2400 | Rheic Acid | Rhein (Monorhein, NSC 38629, Rheinic) is an anthraquinone compound enriched in the fresh rhizome of Rheum coreanum Nakai, showing anti-inflammation and antitumor activities. Rhein is an FTO (mRNA N6-methyladenine demethylase) inhibitor and also inhibits AlkB repair enzymes. |
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| S9946 | Bisantrene (CS1) |
Bisantrene (CS1, NSC-337766, CL 216,942) is an anthracene derivative with anti-tumor activity and a potent and selective FTO inhibitor. |
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| S4295 | Meclofenamate Sodium | Meclofenamate Sodium(CI 583) is a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively, used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. This compound is a non-selective gap-junction blocker and a highly selective inhibitor of fat mass and obesity-associated (FTO) enzyme inhibitor. |
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