COMT

Inhibitory Selectivity

COMT Products

All (2) COMT Inhibitors (2)

Catalog No.	Information	Product Use Citations	Product Validations
S3147	Entacapone Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.	bioRxiv, 2021, 10.1101/2021.03.22.436393
S4021	Tolcapone Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with K_i of 30 nM.	Viruses, 2021, 13(8)1533

Catalog No.

Information

Product Use Citations

Product Validations

S3147

Entacapone

Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.

bioRxiv, 2021, 10.1101/2021.03.22.436393

S4021

Tolcapone

Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with K_i of 30 nM.

Viruses, 2021, 13(8)1533

Catalog No.	Information	Product Use Citations	Product Validations
S3147	Entacapone Entacapone (OR-611) inhibits catechol-O-methyltransferase(COMT) with IC50 of 151 nM. Entacapone can be used for the research of Parkinson's disease. Entacapone serves as a inhibitor of FTO demethylation with an IC50 of 3.5 μM, can be used for the research of metabolic disorders.	bioRxiv, 2021, 10.1101/2021.03.22.436393
S4021	Tolcapone Tolcapone (Ro 40-7592) is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with K_i of 30 nM.	Viruses, 2021, 13(8)1533

Catalog No.

Information

Product Use Citations

Product Validations

S3147