| S1950 |
Metformin Hydrochloride
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Metformin Hydrochloride (1,1-Dimethylbiguanide Hydrochloride) is a highly effective Antihyperglycemic Agent, which primarily decreases hyperglycemia in hepatocytes by suppressing hepatic gluconeogenesis (glucose production by the liver). It also promotes mitophagy in mononuclear cells and induces apoptosis of lung cancer cells through activating the JNK/p38 MAPK pathway and GADD153.
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Cell Biosci, 2025, 15(1):156
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mBio, 2025, e0063425
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Placenta, 2025, 165:50-61
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| S1271 |
Acarbose
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Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.
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Cell Metabolism, March 13, 2026, S1550-4131(26)00055-0
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Biochemical and Biophysical Research Communications, February 05, 2024, 149467
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Communications Medicine, 2025, Article number: 1136
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