IPA-3

Catalog No.S7093

IPA-3 Chemical Structure

Molecular Weight(MW): 350.45

IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6).

Size Price Stock Quantity  
USD 70 In stock
USD 370 In stock
Bulk Discount

Free Overnight Delivery on orders over $ 500
Next day delivery by 10:00 a.m. Order now.

1 Customer Review

  • (e) Immunoblot analysis of p-ERM, p-Pak1 and Pak1 in Ishikawa cells treated with various doses of Pak1 inhibitor IPA-3 for 24 h. Actin serves as a loading control

    Cell Death Differ, 2016, 23(1):169-81. IPA-3 purchased from Selleck.

Purity & Quality Control

Choose Selective PAK Inhibitors

Biological Activity

Description IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6).
Features IPA-3 binds covalently to the Pak1 regulatory domain and prevents binding to the upstream activator Cdc42.
Targets
PAK1 [1]
(Cell-free assay)
2.5 μM
In vitro

IPA-3 is a non ATP-competitive, allosteric inhibitor of p21-activated kinase 1 (Pak1). PIR3.5 is the control compound of IPA-3. IPA-3 prevents Cdc42-stimulated Pak1 autophosphorylation on Thr423. IPA-3 also prevents sphingosine-dependent Pak1 autophosphorylation. IPA-3 does not target exposed cysteine residues on Pak1. The disulfide bond of IPA-3 is critical for inhibition of Pak1 and in vitro reduction by the reducing agent dithiothreitol (DTT) abolishes Pak1 inhibition by IPA-3. IPA-3 inhibits activation of Pak1 by diverse activators, but does not inhibit preactivated Pak1. IPA-3 inhibits PDGF-stimulated Pak activation in mouse embryonic fibroblasts. [1] IPA-3 inhibits Pak1 activation in part by binding covalently to the regulatory domain of Pak1. IPA-3 binds Pak1 covalently in a time- and temperature-dependent manner. IPA-3 prevents binding of the Pak1 activator Cdc42. IPA-3 binds directly to the Pak1 autoregulatory domain. IPA-3 reversibly inhibits PMA-induced membrane ruffling in cells. [2]

Cell Data
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
human NALM-6 cell NVXIRpF1T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\RcpN5UW6qaXLpeIlwdiCxZjDoeY1idiCQQVzNMVYh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0xNjl5Nkm0JO69VQ>? MoCzV2FPT0WU
human SW1710 cell MWDHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NInvO4VKdmirYnn0bY9vKG:oIHj1cYFvKFOZMUexNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVEvOTd6M{Og{txO M1PCfnNCVkeHUh?=
human YT cell MoO5S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? Mmi5TY5pcWKrdHnvckBw\iCqdX3hckB[XCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTFwM{mwN|Yh|ryP M{jvV3NCVkeHUh?=
human BL-70 cell NUGwT|ltT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MoTqTY5pcWKrdHnvckBw\iCqdX3hckBDVC15MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUKuNFM4QTZizszN MVrTRW5ITVJ?
human SIG-M5 cell NWLUOI03T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NU\5SGpQUW6qaXLpeIlwdiCxZjDoeY1idiCVSVetUVUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0zNjFyMkG5JO69VQ>? NGLHfmxUSU6JRWK=
human MCF7 cell M2ey[2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NHXzUZhKdmirYnn0bY9vKG:oIHj1cYFvKE2FRkegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlE5ODdizszN NYjBdY1nW0GQR1XS
human GB-1 cell NFe3VZBIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVnmXGFQUW6qaXLpeIlwdiCxZjDoeY1idiCJQj2xJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9Nk43OzR7NDFOwG0> MkXUV2FPT0WU
human KU812 cell NUDt[mdiT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M2j0UWlvcGmkaYTpc44hd2ZiaIXtZY4hU1V6MUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2yMlc2QTVizszN M4m5fHNCVkeHUh?=
human QIMR-WIL cell NGPvTHJIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NVLS[oNNUW6qaXLpeIlwdiCxZjDoeY1idiCTSV3SMXdKVCClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTJwOUC4PVEh|ryP M3HHenNCVkeHUh?=
human BL-41 cell NUD2W5hyT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MlW2TY5pcWKrdHnvckBw\iCqdX3hckBDVC12MTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuNFk5PDRizszN MXrTRW5ITVJ?
human CMK cell MXzHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NYDUW4VuUW6qaXLpeIlwdiCxZjDoeY1idiCFTVugZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2zMlE1PTl7IN88US=> NFvxNWtUSU6JRWK=
human U-698-M cell MUHHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M4LQeWlvcGmkaYTpc44hd2ZiaIXtZY4hXS14OUitUUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOjN6NU[g{txO MV\TRW5ITVJ?
human Daoy cell M2LQeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 Mk\LTY5pcWKrdHnvckBw\iCqdX3hckBF[W:7IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz6yOFY3OiEQvF2= MXTTRW5ITVJ?
human 786-0 cell MljnS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NXv4[XFLUW6qaXLpeIlwdiCxZjDoeY1idiB5OE[tNEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvOzF6MEWg{txO MYHTRW5ITVJ?
human REH cell NViybnBvT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIDBU4hKdmirYnn0bY9vKG:oIHj1cYFvKFKHSDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUOuN|Y3PTVizszN NGT1dIlUSU6JRWK=
human MHH-PREB-1 cell NHHqb4lIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NXi5bFFTUW6qaXLpeIlwdiCxZjDoeY1idiCPSFitVHJGSi1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz60OlY5PyEQvF2= NFu4e5VUSU6JRWK=
human KE-37 cell growth MlvZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NITqb2NKdmirYnn0bY9vKG:oIHj1cYFvKEuHLUO3JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9N{42ODJ|MTFOwG0> M3zPRXNCVkeHUh?=
human CAL-51 cell MlTuS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NEj0c|ZKdmirYnn0bY9vKG:oIHj1cYFvKEODTD21NUBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVMvPTR3MUmg{txO NH7KOYhUSU6JRWK=
human CA46 cell NE\y[5ZIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MnPITY5pcWKrdHnvckBw\iCqdX3hckBESTR4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;Mz62OlE5KM7:TR?= NYDhTJNnW0GQR1XS
human HEL cell M2q5OWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MmG2TY5pcWKrdHnvckBw\iCqdX3hckBJTUxiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkeyO|Y5KM7:TR?= MVPTRW5ITVJ?
human NB6 cell M2Tubmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 MoXqTY5pcWKrdHnvckBw\iCqdX3hckBPSjZiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD1|LkizO|UyKM7:TR?= MoS3V2FPT0WU
human 8305C cell M3\PN2dzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NUe0PGJyUW6qaXLpeIlwdiCxZjDoeY1idiB6M{C1R{Bk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVQvOTZ5NUig{txO NXjOVWIzW0GQR1XS
human EW-13 cell MVvHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MY\Jcohq[mm2aX;uJI9nKGi3bXHuJGVYNTF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND6yNFE1QCEQvF2= NWnqWVRIW0GQR1XS
human NB13 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MmT2TY5pcWKrdHnvckBw\iCqdX3hckBPSjF|IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND6yNlU3KM7:TR?= NFm3[HBUSU6JRWK=
human EB2 cell NXvnPJltT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= M{SxNWlvcGmkaYTpc44hd2ZiaIXtZY4hTUJ{IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND60PVE1OiEQvF2= NIPqTphUSU6JRWK=
human HOS cell NFTnPWFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MYjJcohq[mm2aX;uJI9nKGi3bXHuJGhQWyClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7 NWnjb3FpW0GQR1XS
human HLE cell M2PlTmdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 M4[wbmlvcGmkaYTpc44hd2ZiaIXtZY4hUEyHIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND61NlE1QSEQvF2= NHjWVmxUSU6JRWK=
human ST486 cell MkLZS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MV;Jcohq[mm2aX;uJI9nKGi3bXHuJHNVPDh4IHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;ND64OlU1KM7:TR?= NIGy[JpUSU6JRWK=
human NCI-H2009 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M1XTUGlvcGmkaYTpc44hd2ZiaIXtZY4hVkOLLViyNFA6KGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:PS5yNEO1OEDPxE1? NHv2eGFUSU6JRWK=
human NH-12 cell NFfxUYFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M4HQXGlvcGmkaYTpc44hd2ZiaIXtZY4hVkhvMUKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21MlEyPzZizszN MlfZV2FPT0WU
human BFTC-905 cell MU\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M{jQPGlvcGmkaYTpc44hd2ZiaIXtZY4hSk[WQz25NFUh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02NjF2N{[4JO69VQ>? M4KwNnNCVkeHUh?=
human RKO cell Mn\DS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? NGn3OFBKdmirYnn0bY9vKG:oIHj1cYFvKFKNTzDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuNlg1PzFizszN MVnTRW5ITVJ?
human PF-382 MlTJS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MWrJcohq[mm2aX;uJI9nKGi3bXHuJHBHNTN6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuN|UzOjZizszN NV7MUVVJW0GQR1XS
human SR cell NEH6b3JIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M3v3[2lvcGmkaYTpc44hd2ZiaIXtZY4hW1JiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD13LkO3NlU3KM7:TR?= NYLlOo94W0GQR1XS
human WSU-NHL cell MX7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NGiwSWhKdmirYnn0bY9vKG:oIHj1cYFvKFeVVT3OTGwh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF02NjV{ME[3JO69VQ>? MVPTRW5ITVJ?
human CAL-12T cell NHzEfXFIem:5dHigbY5pcWKrdHnvckBie3OjeR?= M1PZT2lvcGmkaYTpc44hd2ZiaIXtZY4hS0GOLUGyWEBk\WyuIHfyc5d1cCCrbjDhJINmdGxidnnhZoltcXS7IHHzd4F6NCCLQ{WwQVUvPjRzNDFOwG0> NIDXOXdUSU6JRWK=
human Daudi cell MmS2S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MofRTY5pcWKrdHnvckBw\iCqdX3hckBF[XWmaTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUWuOlg1PzdizszN NES3RmpUSU6JRWK=
human MC-CAR cell NFjsUIdIem:5dHigbY5pcWKrdHnvckBie3OjeR?= Mk\2TY5pcWKrdHnvckBw\iCqdX3hckBOSy2FQWKgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME21MlcxPjR2IN88US=> NUXDPZc6W0GQR1XS
human RPMI-8402 cell NWCzNGRLT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NInrdmpKdmirYnn0bY9vKG:oIHj1cYFvKFKSTVmtPFQxOiClZXzsJIdzd3e2aDDpckBiKGOnbHygeoli[mmuaYT5JIF{e2G7LDDJR|UxRTVwN{[4O|Yh|ryP MXnTRW5ITVJ?
human CCRF-CEM cell Mn[3S5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MUPJcohq[mm2aX;uJI9nKGi3bXHuJGNEWkZvQ1XNJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9OU46PzZ4NzFOwG0> MVPTRW5ITVJ?
human CHP-126 cell MlTwS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MVXJcohq[mm2aX;uJI9nKGi3bXHuJGNJWC1zMk[gZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22Mlc1OjZ6IN88US=> NFjucGtUSU6JRWK=
human NB69 cell NEHofYlIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NFTrPIhKdmirYnn0bY9vKG:oIHj1cYFvKE6ENkmgZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME22Mlc3OzV{IN88US=> MVrTRW5ITVJ?
human KS-1 cell MV7Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? M2G2fWlvcGmkaYTpc44hd2ZiaIXtZY4hU1NvMTDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPU[uPFg2PDlizszN NXHIXJpFW0GQR1XS
human J82 cell NXzDXXQ3T3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NH:3VVZKdmirYnn0bY9vKG:oIHj1cYFvKEp6MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuNFQ6PjVizszN NE\vdoZUSU6JRWK=
human SW872 cell MVXHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? MkfyTY5pcWKrdHnvckBw\iCqdX3hckBUXzh5MjDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUeuPFM2PThizszN NWq4XI41W0GQR1XS
human HC-1 cell NWHMbJBDT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= MULJcohq[mm2aX;uJI9nKGi3bXHuJGhENTFiY3XscEBoem:5dHigbY4h[SClZXzsJJZq[WKrbHn0fUBie3OjeTygTWM2OD16LkC2PFA2KM7:TR?= M{exenNCVkeHUh?=
human DU-145 cell MmfUS5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? M3PDdWlvcGmkaYTpc44hd2ZiaIXtZY4hTFVvMUS1JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE4zOTR4NDFOwG0> M4HpVnNCVkeHUh?=
human HL-60 cell NGP2RYpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= NF7WN2tKdmirYnn0bY9vKG:oIHj1cYFvKEiOLU[wJINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9PE45PDZyNTFOwG0> MWjTRW5ITVJ?
human MV-4-11 cell M1PCWWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NVi1VIpvUW6qaXLpeIlwdiCxZjDoeY1idiCPVj20MVEyKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:QS5zNkS5JO69VQ>? MVrTRW5ITVJ?
human SK-N-DZ cell NVfzRWxXT3Kxd4ToJIlvcGmkaYTpc44h[XO|YYm= NIXveFFKdmirYnn0bY9vKG:oIHj1cYFvKFONLV6tSHoh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF06NjJyNEKzJO69VQ>? Mne3V2FPT0WU
human HT-1197 cell NIfXdGpIem:5dHigbY5pcWKrdHnvckBie3OjeR?= MWPJcohq[mm2aX;uJI9nKGi3bXHuJGhVNTFzOUegZ4VtdCCpcn;3eIghcW5iYTDj[YxtKH[rYXLpcIl1gSCjc4PhfUwhUUN3ME2xNE4{ODd|IN88US=> M4Hve3NCVkeHUh?=
human NOS-1 cell MlnES5Jwf3SqIHnubIljcXSrb36gZZN{[Xl? MXjJcohq[mm2aX;uJI9nKGi3bXHuJG5QWy1zIHPlcIwh\3Kxd4ToJIlvKGFiY3XscEB3cWGkaXzpeJkh[XO|YYmsJGlEPTB;MUGuO|E2OiEQvF2= NGHrSHlUSU6JRWK=
human HT-1080 cell MW\Hdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? NFW2N4VKdmirYnn0bY9vKG:oIHj1cYFvKEiWLUGwPFAh[2WubDDndo94fGhiaX6gZUBk\WyuII\pZYJqdGm2eTDhd5NigSxiSVO1NF0yQC54MkizJO69VQ>? MXrTRW5ITVJ?
human SK-LU-1 cell M2\CeWdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYnkPGVqUW6qaXLpeIlwdiCxZjDoeY1idiCVSz3MWU0yKGOnbHyg[5Jwf3SqIHnuJIEh[2WubDD2bYFjcWyrdImgZZN{[XluIFnDOVA:OThwOEezNUDPxE1? MkeyV2FPT0WU
human SW48 cell M{D6bGdzd3e2aDDpcohq[mm2aX;uJIF{e2G7 NYHSVog3UW6qaXLpeIlwdiCxZjDoeY1idiCVV{S4JINmdGxiZ4Lve5RpKGmwIHGgZ4VtdCC4aXHibYxqfHliYYPzZZktKEmFNUC9NlEvQDh7NzFOwG0> NH;GRpBUSU6JRWK=
human A2780 cell MXjHdo94fGhiaX7obYJqfGmxbjDhd5NigQ>? Mn7YTY5pcWKrdHnvckBw\iCqdX3hckBCOjd6MDDj[YxtKGe{b4f0bEBqdiCjIHPlcIwhfmmjYnnsbZR6KGG|c3H5MEBKSzVyPUK4MlM4OSEQvF2= NHHjZ4hUSU6JRWK=

... Click to View More Cell Line Experimental Data

Protocol

Solubility (25°C)

In vitro DMSO 70 mg/mL (199.74 mM)
Ethanol 7 mg/mL (19.97 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 350.45
Formula

C20H14O2S2

CAS No. 42521-82-4
Storage powder
in solvent
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

  • * Indicates a Required Field

PAK Signaling Pathway Map

Tags: buy IPA-3 | IPA-3 supplier | purchase IPA-3 | IPA-3 cost | IPA-3 manufacturer | order IPA-3 | IPA-3 distributor
×
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID