Domvanalimab (Anti-TIGIT) | Read Reviews & Product Use Citations

Domvanalimab (Anti-TIGIT) is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting the co-inhibitory molecule and immune checkpoint inhibitor T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) with potential immune checkpoint inhibitory activity. MW : 145.12 KD.

Purity & Quality Control

Batch: A283201 Purity: 99% Protein concentration: 4.35mg/ml Endotoxin Level: ＜1EU/mg

99

Biological Activity

Description	Domvanalimab (Anti-TIGIT) is a humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting the co-inhibitory molecule and immune checkpoint inhibitor T-cell immunoreceptor with immunoglobulin (Ig) and immunoreceptor tyrosine-based inhibitory motif (ITIM) domains (TIGIT) with potential immune checkpoint inhibitory activity. MW : 145.12 KD.

References
[1] Dolgin E. et al. Nat Biotechnol. 2020;38(9):1007-1009.

References

[1] Dolgin E. et al. Nat Biotechnol. 2020;38(9):1007-1009.

Product Details

CAS No.	2368219-35-4
Molecular Weight	145.12
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100mMPro-Ac,20mMArg-Ac，pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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