Diphenidol HCl

Synonyms: Diphenidol hydrochloride

Diphenidol HCl(Diphenidol hydrochloride) is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.

Diphenidol HCl Chemical Structure

Diphenidol HCl Chemical Structure

CAS: 3254-89-5

Purity & Quality Control

Batch: S429201 DMSO] 69 mg/mL] false] Ethanol] 36 mg/mL] false] Water] 13 mg/mL] false Purity: 99.94%
99.94

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Biological Activity

Description Diphenidol HCl(Diphenidol hydrochloride) is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.
Targets
M2 mAChR [1] M2 mAChR [1] M3 mAChR [1]

Chemical Information & Solubility

Molecular Weight 345.91 Formula

C21H28ClNO

CAS No. 3254-89-5 SDF Download Diphenidol HCl SDF
Smiles C1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.Cl
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 69 mg/mL ( (199.47 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 36 mg/mL

Water : 13 mg/mL


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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