Diphenidol HCl

Catalog No.S4292

Diphenidol HCl Chemical Structure

Molecular Weight(MW): 345.91

Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.

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Biological Activity

Description Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.
Targets
M2 mAChR [1] M2 mAChR [1] M3 mAChR [1]

Protocol

References

Solubility (25°C)

In vitro DMSO 69 mg/mL (199.47 mM)
Ethanol 36 mg/mL warmed (104.07 mM)
Water 13 mg/mL (37.58 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 345.91
Formula

C21H28ClNO

CAS No. 3254-89-5
Storage powder
Synonyms N/A

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT01574313 Completed Vertigo|Meniere Disease Chi Mei Medical Hospital April 2010 Phase 4

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AChR Signaling Pathway Map

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