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BAY 61-3606

Cat.No.E7930

BAY 61-3606 is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM and an IC50 of 10 nM. This compound reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell. It induces a large decrease of Syk phosphorylation in K-rn cell lysates. This chemical sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells.
BAY 61-3606 Chemical Structure

Chemical Structure

Molecular Weight: 390.40

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Chemical Information, Storage & Stability

Molecular Weight 390.40 Formula Storage (From the date of receipt)
CAS No. 732983-37-8 -- Storage of Stock Solutions Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

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