Anti-mouse TIM-3 (CD366)-InVivo | Immunology & Inflammation related

Anti-mouse TIM-3 (CD366)-InVivo monoclonal antibody reacts with mouse TIM-3 (T cell immunoglobulin and mucin domain-3) also known as CD366. TIM-3 is specifically expressed at high levels on the surface of Th1 lymphocytes. This B8.2C12 antibody binds to the BALB/c allele of TIM-3 while reactivity to the C57Bl/6 allele. Inhibition of TIM-3 signaling in mice exacerbates experimental autoimmune encephalomyelitis and promotes IFNγ production and Th1 cell proliferation.

Purity & Quality Control

Batch: Purity: 99% Protein concentration: 5.49 mg/ml Endotoxin Level: ＜1EU/mg

99

Product Details

Molecular Weight	150 kDa
Clone	B8.2C12
Isotype	Rat IgG2a, κ
Application	Anti-mouse TIM-3 (CD366)-InVivo
Purification	Protein G
Sterility	0.2 μM filtered
Formulation	PBS, pH 7.0 Contains no stabilizers or preservatives
Storage (From the date of receipt)	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles

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